PL3533792T3 - Postacie krystaliczne modulatora receptora androgenowego - Google Patents

Postacie krystaliczne modulatora receptora androgenowego

Info

Publication number: PL3533792T3
Authority: PL; Poland
Prior art keywords: androgen receptor; crystalline forms; receptor modulator; modulator; androgen
Prior art date: 2012-06-07

Application number

PL19169275T

Other languages

English (en)

Inventor

Anna Dilhas

Ouathek Ouerfelli

Nicholas D. Smith

Mark R. Herbert

Original Assignee

Aragon Pharmaceuticals, Inc.

Sloan Kettering Institute For Cancer Research

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-06-07

Filing date

2013-06-04

Publication date

2021-11-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49712550&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3533792(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2013-06-04 Application filed by Aragon Pharmaceuticals, Inc., Sloan Kettering Institute For Cancer Research filed Critical Aragon Pharmaceuticals, Inc.

2021-11-29 Publication of PL3533792T3 publication Critical patent/PL3533792T3/pl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

PL19169275T 2012-06-07 2013-06-04 Postacie krystaliczne modulatora receptora androgenowego PL3533792T3 (pl)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US201261656888P	2012-06-07	2012-06-07
EP19169275.5A EP3533792B1 (en)	2012-06-07	2013-06-04	Crystalline forms of an androgen receptor modulator
EP13800681.2A EP2858985B1 (en)	2012-06-07	2013-06-04	Crystalline forms of an androgen receptor modulator
PCT/US2013/044116 WO2013184681A1 (en)	2012-06-07	2013-06-04	Crystalline forms of an androgen receptor modulator
EP18157435.1A EP3348553B1 (en)	2012-06-07	2013-06-04	Crystalline forms of an androgen receptor modulator

Publications (1)

Publication Number	Publication Date
PL3533792T3 true PL3533792T3 (pl)	2021-11-29

Family

ID=49712550

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
PL13800681T PL2858985T3 (pl)	2012-06-07	2013-06-04	Postacie krystaliczne modulatora receptora androgenowego
PL19169275T PL3533792T3 (pl)	2012-06-07	2013-06-04	Postacie krystaliczne modulatora receptora androgenowego
PL18157435T PL3348553T3 (pl)	2012-06-07	2013-06-04	Postacie krystaliczne modulatora receptora androgenowego

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
PL13800681T PL2858985T3 (pl)	2012-06-07	2013-06-04	Postacie krystaliczne modulatora receptora androgenowego

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL18157435T PL3348553T3 (pl)	2012-06-07	2013-06-04	Postacie krystaliczne modulatora receptora androgenowego

Country Status (42)

Country	Link
US (8)	US9481663B2 (pl)
EP (4)	EP3922629A1 (pl)
JP (3)	JP6182209B2 (pl)
KR (2)	KR102195916B1 (pl)
CN (3)	CN105693692A (pl)
AU (3)	AU2013271751B2 (pl)
BR (1)	BR112014030678A2 (pl)
CA (4)	CA3055660A1 (pl)
CL (1)	CL2014003331A1 (pl)
CO (1)	CO7240407A2 (pl)
CR (2)	CR20190331A (pl)
CY (3)	CY1120393T1 (pl)
DK (3)	DK3533792T3 (pl)
EA (3)	EA028791B1 (pl)
EC (1)	ECSP14030098A (pl)
ES (3)	ES2809738T3 (pl)
FR (1)	FR21C1050I1 (pl)
GT (1)	GT201400283A (pl)
HK (2)	HK1210175A1 (pl)
HR (3)	HRP20180902T1 (pl)
HU (4)	HUE038082T2 (pl)
IL (4)	IL236055A0 (pl)
IN (1)	IN2014DN10084A (pl)
LT (4)	LT3348553T (pl)
ME (2)	ME03081B (pl)
MX (1)	MX356754B (pl)
MY (1)	MY187500A (pl)
NI (1)	NI201400142A (pl)
NO (1)	NO2021046I1 (pl)
NZ (2)	NZ702203A (pl)
PE (2)	PE20150631A1 (pl)
PH (2)	PH12014502714B1 (pl)
PL (3)	PL2858985T3 (pl)
PT (3)	PT2858985T (pl)
RS (3)	RS60617B1 (pl)
SG (3)	SG10201610248SA (pl)
SI (3)	SI3348553T1 (pl)
TR (1)	TR201808939T4 (pl)
TW (1)	TWI532732B (pl)
UA (2)	UA123142C2 (pl)
WO (1)	WO2013184681A1 (pl)
ZA (1)	ZA201500076B (pl)

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US8461343B2 (en)	2007-03-27	2013-06-11	Sloan-Kettering Institute For Cancer Research	Synthesis of thiohydantoins
JP5638003B2 (ja)	2009-01-12	2014-12-10	ユニバーシティオブマサチューセッツローウェル	ポリイソブチレン系ポリウレタン
MD20140054A2 (ro)	2011-12-16	2014-10-31	Olema Pharmaceuticals, Inc.	Compuşi noi de benzopiran, compoziţii şi utilizări ale acestora
DK3533792T3 (da)	2012-06-07	2021-06-28	Aragon Pharmaceuticals Inc	Krystallinske former af en androgenreceptormodulator
SI3725778T1 (sl)	2012-09-11	2022-02-28	Medivation Prostate Therapeutics Llc	Formulacije enzalutamida
MY180834A (en)	2012-09-26	2020-12-10	Aragon Pharmaceuticals Inc	Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
EP2922888B1 (en)	2012-11-21	2021-08-18	The University of Massachusetts	High strength polyisobutylene polyurethanes
JOP20200097A1 (ar) *	2013-01-15	2017-06-16	Aragon Pharmaceuticals Inc	معدل مستقبل أندروجين واستخداماته
JP2017525727A (ja) *	2014-08-26	2017-09-07	アスターバイオテックリミテッドライアビリティカンパニー	プロテインキナーゼ阻害剤
DK3226842T3 (da)	2014-12-05	2021-01-25	Aragon Pharmaceuticals Inc	Anticancersammensætninger
MA41107A (fr)	2014-12-05	2017-10-10	Aragon Pharmaceuticals Inc	Compositions anti-cancéreuses
MD3226843T2 (ro) *	2014-12-05	2021-10-31	Aragon Pharmaceuticals Inc	Compoziții anticancer
WO2016100905A1 (en)	2014-12-19	2016-06-23	Lutron Electronics Co., Inc.	Multi-channel lighting fixture having multiple light-emitting diode drivers
AU2017275396A1 (en)	2016-06-03	2018-11-22	Aragon Pharmaceuticals, Inc.	Anticancer compositions
EP3555061B1 (en)	2016-12-13	2023-06-07	Watson Laboratories Inc.	Solid state forms of apalutamide
EP3592786B1 (en)	2017-03-07	2023-05-10	Cardiac Pacemakers, Inc.	Hydroboration/oxidation of allyl-terminated polyisobutylene
EP3668912B1 (en)	2017-08-17	2021-06-30	Cardiac Pacemakers, Inc.	Photocrosslinked polymers for enhanced durability
AU2018351714A1 (en)	2017-10-16	2020-04-30	Aragon Pharmaceuticals, Inc.	Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer
WO2019135254A1 (en) *	2018-01-02	2019-07-11	Mylan Laboratories Limited	Apalutamide polymorphs and their preparation thereof
EP3740253B1 (en)	2018-01-17	2023-08-16	Cardiac Pacemakers, Inc.	End-capped polyisobutylene polyurethane
US20200270226A1 (en) *	2018-06-20	2020-08-27	Crystal Pharmaceutical (Suzhou) Co., Ltd.	Crystalline forms of arn-509, preparation method and use thereof
WO2020049598A2 (en)	2018-09-08	2020-03-12	Cipla Limited	Apalutamide polymorphs
IT201900003839A1 (it)	2019-03-15	2020-09-15	Olon Spa	Sintesi di apalutamide amorfa stabile
WO2020234817A1 (en) *	2019-05-21	2020-11-26	Laurus Labs Limited	Polymorphic forms of apalutamide and its preparation thereof
IT201900010593A1 (it) *	2019-07-01	2021-01-01	Dipharma Francis Srl	Forma cristallina di un inibitore di recettori degli androgeni
WO2021033098A1 (en) *	2019-08-22	2021-02-25	Dr. Reddy’S Laboratories Limited	Process for the preparation of apalutamide
IT201900015974A1 (it)	2019-09-10	2021-03-10	Olon Spa	Apalutamide cristallina stabile in forma pura e processo per la sua preparazione
CN110590740A (zh) *	2019-09-20	2019-12-20	武汉大学	一种阿帕鲁胺化合物及其药物制剂
WO2022049265A1 (en)	2020-09-04	2022-03-10	Synthon B.V.	Improved process for preparation of apalutamide
WO2023143090A1 (zh) *	2022-01-25	2023-08-03	成都苑东生物制药股份有限公司	一种阿帕他胺溶剂化物新晶型及其制备方法
CN115536634A (zh) *	2022-10-17	2022-12-30	上海博悦生物科技有限公司	一种阿帕他胺的合成方法

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US5323907A (en)	1992-06-23	1994-06-28	Multi-Comp, Inc.	Child resistant package assembly for dispensing pharmaceutical medications
US7709517B2 (en) *	2005-05-13	2010-05-04	The Regents Of The University Of California	Diarylhydantoin compounds
CN101032483B (zh) *	2006-03-09	2011-05-04	陈德桂	调节雄激素受体活性的乙内酰脲衍生物及其应用
EP3412290B1 (en) *	2006-03-27	2021-03-03	The Regents of The University of California	Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases
CN101460467B (zh)	2006-03-29	2012-09-19	加利福尼亚大学董事会	二芳基硫代乙内酰脲化合物
US8461343B2 (en)	2007-03-27	2013-06-11	Sloan-Kettering Institute For Cancer Research	Synthesis of thiohydantoins
SI3124481T1 (en) *	2010-02-16	2018-06-29	Aragon Pharmaceuticals, Inc.	Androgen receptor modulators and their use
DK3533792T3 (da)	2012-06-07	2021-06-28	Aragon Pharmaceuticals Inc	Krystallinske former af en androgenreceptormodulator
US20200270226A1 (en)	2018-06-20	2020-08-27	Crystal Pharmaceutical (Suzhou) Co., Ltd.	Crystalline forms of arn-509, preparation method and use thereof

2013
- 2013-06-04 DK DK19169275.5T patent/DK3533792T3/da active
- 2013-06-04 CR CR20190331A patent/CR20190331A/es unknown
- 2013-06-04 DK DK13800681.2T patent/DK2858985T3/en active
- 2013-06-04 LT LTEP18157435.1T patent/LT3348553T/lt unknown
- 2013-06-04 WO PCT/US2013/044116 patent/WO2013184681A1/en active Application Filing
- 2013-06-04 SI SI201331788T patent/SI3348553T1/sl unknown
- 2013-06-04 CN CN201610202980.2A patent/CN105693692A/zh active Pending
- 2013-06-04 SG SG10201610248SA patent/SG10201610248SA/en unknown
- 2013-06-04 PL PL13800681T patent/PL2858985T3/pl unknown
- 2013-06-04 HU HUE13800681A patent/HUE038082T2/hu unknown
- 2013-06-04 NZ NZ702203A patent/NZ702203A/en unknown
- 2013-06-04 CA CA3055660A patent/CA3055660A1/en not_active Abandoned
- 2013-06-04 UA UAA201702779A patent/UA123142C2/uk unknown
- 2013-06-04 ME MEP-2018-158A patent/ME03081B/me unknown
- 2013-06-04 EP EP21171579.2A patent/EP3922629A1/en active Pending
- 2013-06-04 JP JP2015516121A patent/JP6182209B2/ja active Active
- 2013-06-04 EA EA201492272A patent/EA028791B1/ru unknown
- 2013-06-04 MX MX2014015005A patent/MX356754B/es active IP Right Grant
- 2013-06-04 ES ES18157435T patent/ES2809738T3/es active Active
- 2013-06-04 CN CN201380041652.3A patent/CN104619692A/zh active Pending
- 2013-06-04 CA CA3114726A patent/CA3114726A1/en active Pending
- 2013-06-04 EP EP19169275.5A patent/EP3533792B1/en active Active
- 2013-06-04 CA CA2875767A patent/CA2875767C/en active Active
- 2013-06-04 SG SG10201610249TA patent/SG10201610249TA/en unknown
- 2013-06-04 LT LTEP13800681.2T patent/LT2858985T/lt unknown
- 2013-06-04 KR KR1020197033592A patent/KR102195916B1/ko active IP Right Grant
- 2013-06-04 MY MYPI2014703627A patent/MY187500A/en unknown
- 2013-06-04 RS RS20200913A patent/RS60617B1/sr unknown
- 2013-06-04 HU HUE19169275A patent/HUE054595T2/hu unknown
- 2013-06-04 RS RS20210739A patent/RS61988B1/sr unknown
- 2013-06-04 IN IN10084DEN2014 patent/IN2014DN10084A/en unknown
- 2013-06-04 EP EP13800681.2A patent/EP2858985B1/en active Active
- 2013-06-04 SI SI201331010T patent/SI2858985T1/sl unknown
- 2013-06-04 TR TR2018/08939T patent/TR201808939T4/tr unknown
- 2013-06-04 EP EP18157435.1A patent/EP3348553B1/en active Active
- 2013-06-04 EA EA201992010A patent/EA201992010A1/ru unknown
- 2013-06-04 US US14/406,520 patent/US9481663B2/en active Active
- 2013-06-04 CN CN202110417935.XA patent/CN113135892A/zh active Pending
- 2013-06-04 RS RS20180680A patent/RS57370B1/sr unknown
- 2013-06-04 PT PT138006812T patent/PT2858985T/pt unknown
- 2013-06-04 CA CA3008345A patent/CA3008345C/en active Active
- 2013-06-04 PL PL19169275T patent/PL3533792T3/pl unknown
- 2013-06-04 HU HUE18157435A patent/HUE050357T2/hu unknown
- 2013-06-04 NZ NZ717683A patent/NZ717683A/en unknown
- 2013-06-04 DK DK18157435.1T patent/DK3348553T3/da active
- 2013-06-04 SI SI201331894T patent/SI3533792T1/sl unknown
- 2013-06-04 ES ES13800681.2T patent/ES2670683T3/es active Active
- 2013-06-04 PE PE2014002383A patent/PE20150631A1/es active IP Right Grant
- 2013-06-04 PE PE2019002096A patent/PE20200725A1/es unknown
- 2013-06-04 EA EA201791592A patent/EA033956B1/ru unknown
- 2013-06-04 PT PT191692755T patent/PT3533792T/pt unknown
- 2013-06-04 AU AU2013271751A patent/AU2013271751B2/en active Active
- 2013-06-04 ES ES19169275T patent/ES2875932T3/es active Active
- 2013-06-04 LT LTEP19169275.5T patent/LT3533792T/lt unknown
- 2013-06-04 SG SG11201408140QA patent/SG11201408140QA/en unknown
- 2013-06-04 PL PL18157435T patent/PL3348553T3/pl unknown
- 2013-06-04 ME MEP-2020-163A patent/ME03815B/me unknown
- 2013-06-04 TW TW102119817A patent/TWI532732B/zh active
- 2013-06-04 BR BR112014030678A patent/BR112014030678A2/pt not_active Application Discontinuation
- 2013-06-04 KR KR1020157000266A patent/KR102062024B1/ko active IP Right Grant
- 2013-06-04 PT PT181574351T patent/PT3348553T/pt unknown
- 2013-06-04 UA UAA201500086A patent/UA115665C2/uk unknown
2014
- 2014-12-01 CR CR20140549A patent/CR20140549A/es unknown
- 2014-12-04 NI NI201400142A patent/NI201400142A/es unknown
- 2014-12-04 PH PH12014502714A patent/PH12014502714B1/en unknown
- 2014-12-04 IL IL236055A patent/IL236055A0/en unknown
- 2014-12-05 EC ECIEPI201430098A patent/ECSP14030098A/es unknown
- 2014-12-05 CL CL2014003331A patent/CL2014003331A1/es unknown
- 2014-12-05 GT GT201400283A patent/GT201400283A/es unknown
- 2014-12-09 CO CO14270612A patent/CO7240407A2/es unknown
2015
- 2015-01-06 ZA ZA2015/00076A patent/ZA201500076B/en unknown
- 2015-11-11 HK HK15111086.5A patent/HK1210175A1/xx unknown
2016
- 2016-07-26 PH PH12016501470A patent/PH12016501470A1/en unknown
- 2016-09-12 US US15/262,522 patent/US9994545B2/en active Active
- 2016-12-19 HK HK16114389A patent/HK1226066A1/zh unknown
2017
- 2017-01-17 AU AU2017200298A patent/AU2017200298B2/en active Active
- 2017-02-15 JP JP2017025746A patent/JP6345821B2/ja active Active
- 2017-12-22 AU AU2017279807A patent/AU2017279807B2/en active Active
2018
- 2018-05-09 US US15/975,449 patent/US10308630B2/en active Active
- 2018-05-23 JP JP2018098638A patent/JP2018141009A/ja active Pending
- 2018-05-31 IL IL259738A patent/IL259738B/en active IP Right Grant
- 2018-06-11 HR HRP20180902TT patent/HRP20180902T1/hr unknown
- 2018-07-06 CY CY20181100712T patent/CY1120393T1/el unknown
2019
- 2019-04-15 US US16/384,002 patent/US10526310B2/en active Active
- 2019-06-24 IL IL267608A patent/IL267608A/en unknown
- 2019-07-10 US US16/507,780 patent/US10556882B2/en active Active
- 2019-12-11 US US16/710,785 patent/US10766875B2/en active Active
2020
- 2020-06-15 IL IL275413A patent/IL275413A/en unknown
- 2020-07-29 US US16/942,069 patent/US10934271B2/en active Active
- 2020-08-31 HR HRP20201387TT patent/HRP20201387T1/hr unknown
- 2020-09-23 CY CY20201100901T patent/CY1123427T1/el unknown
2021
- 2021-01-26 US US17/158,806 patent/US20210163441A1/en active Pending
- 2021-06-08 HR HRP20210909TT patent/HRP20210909T1/hr unknown
- 2021-07-02 CY CY20211100595T patent/CY1124831T1/el unknown
- 2021-11-02 NO NO2021046C patent/NO2021046I1/no unknown
- 2021-11-03 LT LTPA2021525C patent/LTPA2021525I1/lt unknown
- 2021-11-03 FR FR21C1050C patent/FR21C1050I1/fr active Active
- 2021-11-04 HU HUS2100047C patent/HUS2100047I1/hu unknown

Also Published As

Publication number	Publication date
HRP20201387T1 (hr)	2020-11-27
IL236055A0 (en)	2015-02-01
ME03081B (me)	2019-01-20
SG10201610248SA (en)	2017-02-27
SG11201408140QA (en)	2015-01-29
IN2014DN10084A (pl)	2015-08-21
KR20150021993A (ko)	2015-03-03
HUE054595T2 (hu)	2021-09-28
PE20150631A1 (es)	2015-05-11
KR102195916B1 (ko)	2020-12-30
US20190241539A1 (en)	2019-08-08
IL275413A (en)	2020-07-30
KR102062024B1 (ko)	2020-01-03
IL259738A (en)	2018-07-31
NO2021046I1 (no)	2021-11-02
HRP20180902T1 (hr)	2018-08-24
TR201808939T4 (tr)	2018-07-23
EP3922629A1 (en)	2021-12-15
CA3055660A1 (en)	2013-12-12
EA033956B1 (ru)	2019-12-13
JP2018141009A (ja)	2018-09-13
PH12014502714A1 (en)	2015-02-02
CO7240407A2 (es)	2015-04-17
CY1120393T1 (el)	2019-07-10
LTPA2021525I1 (pl)	2021-11-25
PL3348553T3 (pl)	2021-02-08
CY1124831T1 (el)	2022-03-24
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HUS2100047I1 (hu)	2021-11-29	Egy androgén receptor modulátor kristályos formái
HK1258404A1 (zh)	2019-11-08	雄激素受體表達的調節
EP2911666A4 (en)	2016-10-12	ANDROGENO-RESISTANT ANDROGEN RECEPTOR MODULATORS
IL266446A (en)	2019-06-30	Androgen synthesis modulators
HK1208867A1 (en)	2016-03-18	Indolecarbonitriles as selective androgen receptor modulators