PL3319611T3 - Oksysterole i sposoby ich stosowania - Google Patents

Oksysterole i sposoby ich stosowania

Info

Publication number
PL3319611T3
PL3319611T3 PL16821924T PL16821924T PL3319611T3 PL 3319611 T3 PL3319611 T3 PL 3319611T3 PL 16821924 T PL16821924 T PL 16821924T PL 16821924 T PL16821924 T PL 16821924T PL 3319611 T3 PL3319611 T3 PL 3319611T3
Authority
PL
Poland
Prior art keywords
oxysterols
methods
Prior art date
Application number
PL16821924T
Other languages
English (en)
Inventor
Francesco G. Salituro
Albert Jean Robichaud
Gabriel Martinez Botella
Original Assignee
Sage Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sage Therapeutics, Inc. filed Critical Sage Therapeutics, Inc.
Publication of PL3319611T3 publication Critical patent/PL3319611T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
PL16821924T 2015-07-06 2016-07-06 Oksysterole i sposoby ich stosowania PL3319611T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562189048P 2015-07-06 2015-07-06
US201662280394P 2016-01-19 2016-01-19
EP16821924.4A EP3319611B1 (en) 2015-07-06 2016-07-06 Oxysterols and methods of use thereof
PCT/US2016/041168 WO2017007836A1 (en) 2015-07-06 2016-07-06 Oxysterols and methods of use thereof

Publications (1)

Publication Number Publication Date
PL3319611T3 true PL3319611T3 (pl) 2021-07-12

Family

ID=57686105

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16821924T PL3319611T3 (pl) 2015-07-06 2016-07-06 Oksysterole i sposoby ich stosowania

Country Status (28)

Country Link
US (3) US10201550B2 (pl)
EP (2) EP3828194A1 (pl)
JP (3) JP2018519351A (pl)
KR (1) KR20180026743A (pl)
CN (2) CN108135912B (pl)
AU (3) AU2016289967B2 (pl)
BR (3) BR122021005552B1 (pl)
CA (1) CA2991214A1 (pl)
CO (1) CO2018000660A2 (pl)
CY (1) CY1124496T1 (pl)
DK (1) DK3319611T3 (pl)
ES (1) ES2865258T3 (pl)
HR (1) HRP20210526T8 (pl)
HU (1) HUE053778T2 (pl)
IL (2) IL256710B2 (pl)
LT (1) LT3319611T (pl)
MA (2) MA55097A (pl)
MD (1) MD3319611T2 (pl)
MX (2) MX2020011449A (pl)
PE (1) PE20180483A1 (pl)
PH (1) PH12018500065A1 (pl)
PL (1) PL3319611T3 (pl)
PT (1) PT3319611T (pl)
RS (1) RS61718B1 (pl)
RU (2) RU2744267C2 (pl)
SG (1) SG10202010553XA (pl)
SI (1) SI3319611T1 (pl)
WO (1) WO2017007836A1 (pl)

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MX2020010690A (es) 2015-07-06 2022-02-25 Sage Therapeutics Inc Oxiesteroles y metodos de uso de los mismos.
PL3436022T3 (pl) 2016-04-01 2022-08-08 Sage Therapeutics, Inc. Oksysterole i sposoby ich stosowania
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WO2023028278A2 (en) * 2021-08-25 2023-03-02 Sage Therapeutics, Inc. Positive nmda-modulating compounds and methods of use thereof
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WO2023114224A1 (en) 2021-12-13 2023-06-22 Sage Therapeutics, Inc. Combination of muscarinic receptor positive modulators and nmda positive allosteric modulators

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Also Published As

Publication number Publication date
IL256710B1 (en) 2023-09-01
CO2018000660A2 (es) 2018-07-10
CA2991214A1 (en) 2017-01-12
JP2018519351A (ja) 2018-07-19
EP3319611A1 (en) 2018-05-16
PH12018500065A1 (en) 2018-07-09
MD3319611T2 (ro) 2021-06-30
AU2021218228A1 (en) 2021-09-09
RS61718B1 (sr) 2021-05-31
RU2744267C2 (ru) 2021-03-04
US20190125764A1 (en) 2019-05-02
EP3319611B1 (en) 2021-01-20
DK3319611T3 (da) 2021-04-12
WO2017007836A1 (en) 2017-01-12
BR122023021450A2 (pt) 2023-12-26
CY1124496T1 (el) 2022-07-22
US20180200267A1 (en) 2018-07-19
KR20180026743A (ko) 2018-03-13
EP3319611A4 (en) 2019-03-06
SG10202010553XA (en) 2020-12-30
AU2021218228B2 (en) 2023-11-16
HUE053778T2 (hu) 2021-07-28
CN113292623A (zh) 2021-08-24
US20210145848A1 (en) 2021-05-20
BR112018000129B1 (pt) 2024-01-09
HRP20210526T1 (hr) 2021-05-28
MX2020011449A (es) 2022-02-28
EP3828194A1 (en) 2021-06-02
BR112018000129A2 (pt) 2018-09-04
MA42410B1 (fr) 2021-04-30
US10765685B2 (en) 2020-09-08
CN108135912A (zh) 2018-06-08
RU2018104278A (ru) 2019-08-06
MX2018000282A (es) 2018-03-08
AU2024200268A1 (en) 2024-02-01
ES2865258T3 (es) 2021-10-15
HRP20210526T8 (hr) 2021-08-20
AU2016289967B2 (en) 2021-09-09
MA42410A (fr) 2018-05-16
AU2016289967A1 (en) 2018-02-01
BR122021005552B1 (pt) 2024-01-02
IL305404A (en) 2023-10-01
JP2021054864A (ja) 2021-04-08
MA55097A (fr) 2022-01-05
RU2018104278A3 (pl) 2019-10-31
SI3319611T1 (sl) 2021-08-31
CN108135912B (zh) 2021-07-02
LT3319611T (lt) 2021-05-10
PE20180483A1 (es) 2018-03-07
JP2022120062A (ja) 2022-08-17
IL256710A (en) 2018-03-29
RU2021100620A (ru) 2021-01-29
IL256710B2 (en) 2024-01-01
PT3319611T (pt) 2021-04-22
US10201550B2 (en) 2019-02-12

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