PL3286325T3 - Sposób i zestaw testowy do izolowania kwasów nukleinowych za pomocą szorstkich powierzchni - Google Patents

Sposób i zestaw testowy do izolowania kwasów nukleinowych za pomocą szorstkich powierzchni

Info

Publication number
PL3286325T3
PL3286325T3 PL16711778.7T PL16711778T PL3286325T3 PL 3286325 T3 PL3286325 T3 PL 3286325T3 PL 16711778 T PL16711778 T PL 16711778T PL 3286325 T3 PL3286325 T3 PL 3286325T3
Authority
PL
Poland
Prior art keywords
nucleic acids
test kit
rough surfaces
rapid isolation
isolation
Prior art date
Application number
PL16711778.7T
Other languages
English (en)
Inventor
Timo Hillebrand
Thorsten Stroh
Original Assignee
Ist Innuscreen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102015211394.9A external-priority patent/DE102015211394B4/de
Priority claimed from DE102015211393.0A external-priority patent/DE102015211393A1/de
Application filed by Ist Innuscreen Gmbh filed Critical Ist Innuscreen Gmbh
Publication of PL3286325T3 publication Critical patent/PL3286325T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0275Interchangeable or disposable dispensing tips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/405Concentrating samples by adsorption or absorption
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02Adapting objects or devices to another
    • B01L2200/023Adapting objects or devices to another adapted for different sizes of tubes, tips or container
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0631Purification arrangements, e.g. solid phase extraction [SPE]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0848Specific forms of parts of containers
    • B01L2300/0854Double walls
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/16Surface properties and coatings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Saccharide Compounds (AREA)
PL16711778.7T 2015-04-23 2016-02-26 Sposób i zestaw testowy do izolowania kwasów nukleinowych za pomocą szorstkich powierzchni PL3286325T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102015207481 2015-04-23
DE102015211394.9A DE102015211394B4 (de) 2015-06-19 2015-06-19 Vorrichtung und Verfahren zur Extraktion von Nukleinsäuren
DE102015211393.0A DE102015211393A1 (de) 2015-06-19 2015-06-19 Vorrichtung und Verfahren zur automatisierten Extraktion von Nukleinsäuren
PCT/EP2016/054178 WO2016169677A1 (de) 2015-04-23 2016-02-26 Verfahren und testkit zur schnellen isolierung von nukleinsäuren mittels rauer oberflächen

Publications (1)

Publication Number Publication Date
PL3286325T3 true PL3286325T3 (pl) 2023-01-23

Family

ID=55628983

Family Applications (2)

Application Number Title Priority Date Filing Date
PL16711778.7T PL3286325T3 (pl) 2015-04-23 2016-02-26 Sposób i zestaw testowy do izolowania kwasów nukleinowych za pomocą szorstkich powierzchni
PL16711779.5T PL3286312T3 (pl) 2015-04-23 2016-02-26 Urządzenie i sposób do ekstrakcji kwasów nukleinowych

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL16711779.5T PL3286312T3 (pl) 2015-04-23 2016-02-26 Urządzenie i sposób do ekstrakcji kwasów nukleinowych

Country Status (8)

Country Link
US (3) US10704039B2 (pl)
EP (3) EP3286312B1 (pl)
JP (4) JP6979940B2 (pl)
CN (3) CN108076644B (pl)
CA (3) CA2983626C (pl)
ES (2) ES2928505T3 (pl)
PL (2) PL3286325T3 (pl)
WO (3) WO2016169679A1 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3286325T3 (pl) 2015-04-23 2023-01-23 Ist Innuscreen Gmbh Sposób i zestaw testowy do izolowania kwasów nukleinowych za pomocą szorstkich powierzchni
DE102017204267B4 (de) 2017-03-14 2021-05-27 Aj Innuscreen Gmbh Verfahren zur anreicherung von zellen aus einer probe und der nachfolgenden nukleinsäureisolierung aus diesen zellen
WO2020153248A1 (ja) 2019-01-25 2020-07-30 積水化学工業株式会社 核酸の単離方法、核酸の単離キット、及び検査チップ
DE102019201966B4 (de) * 2019-02-14 2023-07-27 Axagarius Gmbh & Co. Kg Probentransferwerkzeug
DE102019118332B4 (de) * 2019-07-07 2022-04-07 Ist Innuscreen Gmbh Verfahren und testkit zur bisulfitmodifizierung von dna
DE102020135124A1 (de) 2020-12-30 2022-06-30 Aj Innuscreen Gmbh Verfahren und System zur schnellen Isolierung von Nukleinsäuren direkt aus Vollblutproben
DE102021104319A1 (de) 2021-02-23 2022-08-25 Aj Innuscreen Gmbh Verfahren zur simultanen Isolierung von Nukleinsäuren aus sedimentierbaren und nicht sedimentierbaren Biomolekülen in Wasserproben
CN113546703A (zh) * 2021-07-30 2021-10-26 苏州含光微纳科技有限公司 一种离心式微流控芯片
DE102021130283B4 (de) 2021-11-19 2024-03-21 Ist Innuscreen Gmbh Verfahren und testkit zur preiswerten und ressourcensparenden extraktion von nukleinsäuren
CN113820195B (zh) * 2021-11-25 2022-03-08 成都宜乐芯生物科技有限公司 一种多通道并行前处理装置
DE102022115445B4 (de) 2022-06-21 2024-07-04 Ist Innuscreen Gmbh Verfahren und kit zur manuellen und automatisierten probenvorbereitung von long-read-sequenzierungen

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3717211A1 (de) * 1987-05-22 1988-12-01 Diagen Inst Molekularbio Vorrichtung und verfahren zur trennung und reinigung von molekuelen
US5234809A (en) 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
US5800992A (en) * 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US5871928A (en) * 1989-06-07 1999-02-16 Fodor; Stephen P. A. Methods for nucleic acid analysis
US5114858A (en) * 1990-06-26 1992-05-19 E. I. Du Pont De Nemours And Company Cellular component extraction process in a disposable filtration vessel
US5171537A (en) * 1991-05-06 1992-12-15 Richard E. MacDonald Activated immunodiagnostic pipette tips
DE4139664A1 (de) * 1991-12-02 1993-06-03 Diagen Inst Molekularbio Vorrichtung und verfahren zur isolierung und reinigung von nukleinsaeuren
DE4321904B4 (de) * 1993-07-01 2013-05-16 Qiagen Gmbh Verfahren zur chromatographischen Reinigung und Trennung von Nucleinsäuregemischen
ATE184013T1 (de) 1994-06-14 1999-09-15 Invitek Gmbh Universelles verfahren zur isolierung und reinigung von nukleinsäuren aus extrem geringen mengen sowie sehr stark verunreinigten unterschiedlichsten ausgangsmaterialien
JP3575116B2 (ja) * 1995-06-30 2004-10-13 日本製紙株式会社 印刷用紙及びその製造法
GB9517955D0 (en) * 1995-07-25 1995-11-08 Univ Strathclyde Nucleotide sequence detection and analysis
US6269846B1 (en) * 1998-01-13 2001-08-07 Genetic Microsystems, Inc. Depositing fluid specimens on substrates, resulting ordered arrays, techniques for deposition of arrays
GB9810865D0 (en) * 1998-05-20 1998-07-22 Zeneca Ltd Nucleic acid sequence identification
DE19856064C2 (de) 1998-12-04 2000-11-30 Invitek Gmbh Universelles Verfahren zur Isolierung von DNA aus beliebigen Ausgangsmaterialien
AU777180B2 (en) 1999-07-19 2004-10-07 Organon Teknika B.V. Device and method for mixing magnetic particles with a fluid
DE19937607A1 (de) * 1999-08-09 2001-02-15 Bilatec Ges Zur Entwicklung Bi Reagenzienkit zur Isolierung von Nukleinsäuren
DE29919506U1 (de) * 1999-11-05 2000-02-24 CREAVIS Gesellschaft für Technologie und Innovation mbH, 45772 Marl Mikrostruktuierte Pipetten als Dosiersysteme
WO2001062976A1 (en) 2000-02-23 2001-08-30 Wen Shao Rapid nucleic acid separation, isolation and purification methods
US6565728B1 (en) * 2000-06-08 2003-05-20 Elchrom Scientific Gel cutting and recovering device
CA2428532C (en) * 2000-11-13 2009-05-19 Promega Corporation Lysate clearance and nucleic acid isolation using silanized silica matrices
JP2002212198A (ja) * 2001-01-15 2002-07-31 Jsr Corp 核酸の分離方法および核酸分離用担体
JP2003204799A (ja) * 2002-01-11 2003-07-22 Jsr Corp 白血球含有試料からの核酸分離方法
DE20207793U1 (de) 2002-05-17 2002-08-22 GL BioTech GmbH, 28359 Bremen Kit zur Durchführung eines Verfahrens zur Nukleinsäure-Extraktion und Nukleinsäure-Reinigung
US7722820B2 (en) 2004-11-19 2010-05-25 Phynexus, Inc. Method and device for sample preparation
EP1767623A4 (en) * 2004-06-02 2008-09-17 Arkray Inc CONTAINER FOR NUCLEIC ACID EXTRACTION, METHOD OF CLEANING A SOLID MATRIX AND ASSOCIATED CLEANING MECHANISM, AND METHOD OF PURIFYING NUCLEIC ACID
EP1690938A1 (de) 2005-02-11 2006-08-16 Qiagen GmbH Verfahren zur Isolierung von Nukleinsäuren, wobei die Nukleinsäuren bei erhöhter Temperatur an einer Matrix immobilisiert werden
DE102005053463A1 (de) * 2005-11-06 2007-05-10 Aj Innuscreen Gmbh Vorrichtung und Verfahren zur automatisierten Isolierung und Aufreinigung von Nukleinsäuren aus beliebigen komplexen Ausgangsmaterialien
DE102005059217B4 (de) 2005-12-07 2011-03-17 Aj Innuscreen Gmbh Verfahren und Testkit zur Trennung, Aufreinigung und Wiedergewinnung von lang- und kurzkettigen Nukleinsäuren
US20070281303A1 (en) * 2006-06-05 2007-12-06 Dna Security, Inc. Dna storage and display vessel and method
US20090111193A1 (en) 2007-10-31 2009-04-30 Cooney Christopher G Sample preparation device
JP2011517773A (ja) * 2008-03-28 2011-06-16 バイオティクス, インコーポレイテッド サンプル調製デバイスおよび分析物の処理方法
CN101246178B (zh) * 2008-04-03 2010-05-12 马庆伟 用于吸附、分离、检测超微量靶蛋白的***及其用途
US8105513B2 (en) * 2008-06-06 2012-01-31 Alexander Bonn Pipette tip containing particle-filled polymer monolith
JP2012501177A (ja) * 2008-08-26 2012-01-19 和光純薬工業株式会社 生物学的試料の自動前処理用使い捨て器具
DE102008044721B4 (de) * 2008-08-28 2012-07-19 Forschungszentrum Jülich GmbH Verfahren zur Isolierung von Nukleinsäuren aus nukleinsäurehaltigen Proben sowie ein dazu geeignetes Testkit
EP2396399A4 (en) * 2009-02-14 2014-03-26 Diffinity Genomics Inc SYSTEMS AND METHOD FOR PURIFYING BIOLOGICAL MATERIALS
JP5789799B2 (ja) * 2009-08-21 2015-10-07 国立研究開発法人農業生物資源研究所 多孔質体の製造方法、細胞又は組織供給用支持体の製造方法、及び組織供給体の製造方法
DE102010031401A1 (de) * 2010-07-15 2012-01-19 Aj Innuscreen Gmbh Verfahren zur Anreicherung von Bakterien, Viren sowie Zellen und zur nachfolgenden Nukleinsäureisolierung
GB2502195B (en) * 2010-09-30 2015-02-11 Phynexus Inc Purification of nucleic acids
US20150210951A1 (en) * 2012-07-13 2015-07-30 President And Fellows Of Harvard College Multifunctional repellent materials
CA2883463A1 (en) * 2012-08-28 2014-03-06 Akonni Biosystems Inc. Method and kit for purifying nucleic acids
AU2013202778A1 (en) * 2013-03-14 2014-10-02 Gen-Probe Incorporated Systems, methods, and apparatuses for performing automated reagent-based assays
PL3286325T3 (pl) 2015-04-23 2023-01-23 Ist Innuscreen Gmbh Sposób i zestaw testowy do izolowania kwasów nukleinowych za pomocą szorstkich powierzchni

Also Published As

Publication number Publication date
US20180148766A1 (en) 2018-05-31
EP3286313A1 (de) 2018-02-28
PL3286312T3 (pl) 2022-11-21
CA2983623A1 (en) 2016-10-27
ES2928055T3 (es) 2022-11-15
ES2928505T3 (es) 2022-11-18
US20180133710A1 (en) 2018-05-17
EP3286325A1 (de) 2018-02-28
CA2983619A1 (en) 2016-10-27
WO2016169677A1 (de) 2016-10-27
EP3286312A1 (de) 2018-02-28
JP2018520696A (ja) 2018-08-02
JP2018524017A (ja) 2018-08-30
JP6979940B2 (ja) 2021-12-15
US10851368B2 (en) 2020-12-01
CN108076644A (zh) 2018-05-25
CA2983619C (en) 2022-08-30
EP3286325B1 (de) 2022-07-13
CN108064262A (zh) 2018-05-22
CA2983626C (en) 2023-08-29
JP2022058780A (ja) 2022-04-12
CN108076644B (zh) 2021-12-07
US10934540B2 (en) 2021-03-02
CA2983626A1 (en) 2016-10-27
CN108064262B (zh) 2021-08-31
JP7481376B2 (ja) 2024-05-10
CN108124454A (zh) 2018-06-05
US10704039B2 (en) 2020-07-07
JP6797185B2 (ja) 2020-12-09
CA2983623C (en) 2024-06-18
WO2016169678A1 (de) 2016-10-27
US20180148712A1 (en) 2018-05-31
EP3286312B1 (de) 2022-07-20
JP2018515132A (ja) 2018-06-14
WO2016169679A1 (de) 2016-10-27

Similar Documents

Publication Publication Date Title
PL3286325T3 (pl) Sposób i zestaw testowy do izolowania kwasów nukleinowych za pomocą szorstkich powierzchni
IL283353A (en) hpk1 inhibitors and methods of using them
IL248234A0 (en) A method for preparing nucleic acids, in particular long nucleic acids, use of the method and a kit for applying the method
EP3183367A4 (en) Compositions and methods for enrichment of nucleic acids
EP3256607A4 (en) METHOD FOR HIGH-PARALLEL AND ACCURATE MEASUREMENT OF NUCLEIC ACIDS
SG11201706087VA (en) Devices and methods for diagnostics based on analysis of nucleic acids
EP3607064A4 (en) METHOD AND KIT FOR TARGETED ENRICHMENT OF NUCLEIC ACIDS
EP3418560A4 (en) TEST BENCH AND METHOD FOR USE
HK1243421A1 (zh) 檢測核酸的組合物和方法
EP3402883A4 (en) COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING
EP3327444A4 (en) KIT FOR ANALYSIS AND ANALYSIS PROCEDURE THEREWITH
GB201612094D0 (en) System and method for contamination testing of high-touch surfaces
SG11201800894SA (en) Method for parallel quantification of protein variant
PT3277809T (pt) Isolamento de ácidos nucleicos
EP3173488A4 (en) Use of multiple target nucleic acid detection method using clamping probe and detection probe
EP3305912A4 (en) Detection kit for multiple target nucleic acids and detection method using same
GB2541786B (en) Jig and method of use thereof
SG11202004474XA (en) Method for isolation of nucleic acids
PL3462164T3 (pl) Układ i sposób kontroli ruchomych obiektów w kształcie płyty
PL3337897T3 (pl) Sposób i system do izolacji kwasów nukleinowych
EP3304053A4 (en) Method and apparatus for determining features of hot surface
EP3502275C0 (de) Verfahren zur anreicherung von nukleinsäuren
IL254205A0 (en) Reagents for the acylation of amino acids and methods for their use
GB2535624B (en) Driving simulator and method of use
GB201408204D0 (en) Methods and compositions for identifying nucleic acids