PL3096798T3 - Białka wiążące kalikreinę osocza i ich zastosowanie w leczeniu obrzęku naczynioruchowego - Google Patents

Białka wiążące kalikreinę osocza i ich zastosowanie w leczeniu obrzęku naczynioruchowego

Info

Publication number
PL3096798T3
PL3096798T3 PL15740774T PL15740774T PL3096798T3 PL 3096798 T3 PL3096798 T3 PL 3096798T3 PL 15740774 T PL15740774 T PL 15740774T PL 15740774 T PL15740774 T PL 15740774T PL 3096798 T3 PL3096798 T3 PL 3096798T3
Authority
PL
Poland
Prior art keywords
binding proteins
plasma kallikrein
hereditary angioedema
kallikrein binding
treating hereditary
Prior art date
Application number
PL15740774T
Other languages
English (en)
Inventor
Yung CHYUNG
Daniel J. Sexton
Christopher Tenhoor
Jon A. Kenniston
Ryan Faucette
Ryan Iarrobino
Joseph BIEDENKAPP
Burt Adelman
Original Assignee
Takeda Pharmaceutical Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Company Limited filed Critical Takeda Pharmaceutical Company Limited
Publication of PL3096798T3 publication Critical patent/PL3096798T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/03Phosphotransferases with a nitrogenous group as acceptor (2.7.3)
    • C12Y207/03002Creatine kinase (2.7.3.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21034Plasma kallikrein (3.4.21.34)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL15740774T 2014-01-21 2015-01-21 Białka wiążące kalikreinę osocza i ich zastosowanie w leczeniu obrzęku naczynioruchowego PL3096798T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461929716P 2014-01-21 2014-01-21
US201461944361P 2014-02-25 2014-02-25
US201462021397P 2014-07-07 2014-07-07
EP15740774.3A EP3096798B1 (en) 2014-01-21 2015-01-21 Plasma kallikrein binding proteins and uses thereof in treating hereditary angioedema
PCT/US2015/012212 WO2015112578A1 (en) 2014-01-21 2015-01-21 Plasma kallikrein binding proteins and uses thereof in treating hereditary angioedema

Publications (1)

Publication Number Publication Date
PL3096798T3 true PL3096798T3 (pl) 2021-07-26

Family

ID=53681890

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15740774T PL3096798T3 (pl) 2014-01-21 2015-01-21 Białka wiążące kalikreinę osocza i ich zastosowanie w leczeniu obrzęku naczynioruchowego

Country Status (18)

Country Link
US (2) US11084884B2 (pl)
EP (2) EP3096798B1 (pl)
JP (3) JP6845012B2 (pl)
KR (4) KR102424183B1 (pl)
CN (2) CN116585468A (pl)
AU (3) AU2015209481C1 (pl)
BR (1) BR112016016916B1 (pl)
CA (1) CA2937329C (pl)
DK (1) DK3096798T3 (pl)
EA (1) EA038532B1 (pl)
ES (1) ES2856076T3 (pl)
IL (3) IL246864B (pl)
MX (2) MX2016009428A (pl)
NZ (2) NZ761006A (pl)
PL (1) PL3096798T3 (pl)
PT (1) PT3096798T (pl)
WO (1) WO2015112578A1 (pl)
ZA (2) ZA201605342B (pl)

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EP3459564B1 (en) 2010-01-06 2021-10-27 Takeda Pharmaceutical Company Limited Plasma kallikrein binding proteins
KR102169651B1 (ko) 2011-01-06 2020-10-23 다이액스 코포레이션 혈장 칼리크레인 결합 단백질
US11156612B2 (en) 2013-01-20 2021-10-26 Takeda Pharmaceutical Company Limited Methods of determining levels of cleaved and/or intact kininogen
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ES2856076T3 (es) 2014-01-21 2021-09-27 Takeda Pharmaceuticals Co Proteínas de unión a calicreína plasmática y usos de las mismas en el tratamiento de angioedema hereditario
IL247942B (en) 2014-03-27 2022-09-01 Dyax Corp Compositions and methods for drops in macular edema as a result of diabetes
EP3916020A1 (en) * 2015-03-30 2021-12-01 Dyax Corp. Plasma kallikrein inhibitors and uses thereof for preventing hereditary angioedema attack
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IL311156A (en) 2015-12-11 2024-04-01 Takeda Pharmaceuticals Co Plasma kallikrein inhibitors and their uses in the treatment of hereditary angioedema attack
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CN110997917B (zh) 2017-12-01 2024-04-09 苏州瑞博生物技术股份有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
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IL247942B (en) 2014-03-27 2022-09-01 Dyax Corp Compositions and methods for drops in macular edema as a result of diabetes
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Also Published As

Publication number Publication date
KR102424183B1 (ko) 2022-07-26
MX2016009428A (es) 2017-04-13
KR20160122169A (ko) 2016-10-21
JP2020002171A (ja) 2020-01-09
CN106132442A (zh) 2016-11-16
JP6845012B2 (ja) 2021-03-17
US20210087293A1 (en) 2021-03-25
AU2015209481C1 (en) 2020-10-29
DK3096798T3 (da) 2021-03-01
EP3848057A1 (en) 2021-07-14
US20170002094A1 (en) 2017-01-05
CN106132442B (zh) 2023-07-14
ZA201605342B (en) 2020-11-25
BR112016016916B1 (pt) 2023-12-19
NZ761006A (en) 2023-04-28
JP2017503820A (ja) 2017-02-02
ZA202004653B (en) 2022-01-26
AU2024203436A1 (en) 2024-06-13
JP7164502B2 (ja) 2022-11-01
CA2937329A1 (en) 2015-07-30
IL278062A (en) 2020-11-30
US11084884B2 (en) 2021-08-10
AU2015209481A1 (en) 2016-08-25
AU2020244370A1 (en) 2020-10-29
BR112016016916A8 (pt) 2018-05-02
AU2020244370B2 (en) 2024-03-07
IL263669B (en) 2020-10-29
EP3096798A1 (en) 2016-11-30
BR112016016916A2 (pt) 2018-01-23
NZ723369A (en) 2022-12-23
KR20240033156A (ko) 2024-03-12
IL278062B (en) 2022-06-01
EP3096798B1 (en) 2020-11-25
PT3096798T (pt) 2021-02-25
MX2021013665A (es) 2021-12-10
CA2937329C (en) 2022-05-31
EP3096798A4 (en) 2017-08-23
EA201691470A1 (ru) 2016-12-30
KR20220107077A (ko) 2022-08-01
KR20240049627A (ko) 2024-04-16
CN116585468A (zh) 2023-08-15
IL246864B (en) 2018-12-31
IL263669A (en) 2019-01-31
ES2856076T3 (es) 2021-09-27
JP2023015087A (ja) 2023-01-31
WO2015112578A1 (en) 2015-07-30
EA038532B1 (ru) 2021-09-10
AU2015209481B2 (en) 2020-07-30

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