PL2780373T3 - Przeciwciała anty il-36r - Google Patents
Przeciwciała anty il-36rInfo
- Publication number
- PL2780373T3 PL2780373T3 PL12788410T PL12788410T PL2780373T3 PL 2780373 T3 PL2780373 T3 PL 2780373T3 PL 12788410 T PL12788410 T PL 12788410T PL 12788410 T PL12788410 T PL 12788410T PL 2780373 T3 PL2780373 T3 PL 2780373T3
- Authority
- PL
- Poland
- Prior art keywords
- antibodies
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/715—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons
- G01N2333/7155—Assays involving receptors, cell surface antigens or cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/20—Dermatological disorders
- G01N2800/205—Scaling palpular diseases, e.g. psoriasis, pytiriasis
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161560554P | 2011-11-16 | 2011-11-16 | |
US201261644111P | 2012-05-08 | 2012-05-08 | |
US201261713713P | 2012-10-15 | 2012-10-15 | |
PCT/US2012/064933 WO2013074569A1 (en) | 2011-11-16 | 2012-11-14 | Anti il-36r antibodies |
EP12788410.4A EP2780373B1 (en) | 2011-11-16 | 2012-11-14 | Anti il-36r antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2780373T3 true PL2780373T3 (pl) | 2020-03-31 |
Family
ID=47215803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL12788410T PL2780373T3 (pl) | 2011-11-16 | 2012-11-14 | Przeciwciała anty il-36r |
Country Status (38)
Country | Link |
---|---|
US (3) | US9023995B2 (pl) |
EP (2) | EP3536710A1 (pl) |
JP (3) | JP6289375B2 (pl) |
KR (3) | KR20200110476A (pl) |
CN (3) | CN112812183A (pl) |
AP (1) | AP2014007571A0 (pl) |
AR (1) | AR089178A1 (pl) |
AU (1) | AU2012339734B2 (pl) |
BR (1) | BR112014011594B1 (pl) |
CA (1) | CA2852994C (pl) |
CL (1) | CL2014001123A1 (pl) |
CO (1) | CO7020871A2 (pl) |
CY (1) | CY1122278T1 (pl) |
DK (1) | DK2780373T3 (pl) |
EA (1) | EA031948B1 (pl) |
EC (1) | ECSP14004976A (pl) |
ES (1) | ES2755732T3 (pl) |
FI (1) | FIC20230020I1 (pl) |
FR (1) | FR23C1023I2 (pl) |
HR (1) | HRP20191835T1 (pl) |
HU (2) | HUE047437T2 (pl) |
IL (2) | IL232100B (pl) |
LT (2) | LT2780373T (pl) |
MX (1) | MX347164B (pl) |
MY (1) | MY195289A (pl) |
NL (1) | NL301233I2 (pl) |
PE (1) | PE20142041A1 (pl) |
PH (1) | PH12014501108A1 (pl) |
PL (1) | PL2780373T3 (pl) |
PT (1) | PT2780373T (pl) |
RS (1) | RS59248B1 (pl) |
SG (1) | SG11201402283PA (pl) |
SI (1) | SI2780373T1 (pl) |
TW (1) | TWI573804B (pl) |
UA (1) | UA115540C2 (pl) |
UY (1) | UY34456A (pl) |
WO (1) | WO2013074569A1 (pl) |
ZA (1) | ZA201402491B (pl) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012097313A2 (en) | 2011-01-14 | 2012-07-19 | The Regents Of The University Of California | Therapeutic antibodies against ror-1 protein and methods for use of same |
CN112812183A (zh) | 2011-11-16 | 2021-05-18 | 勃林格殷格翰国际有限公司 | 抗il-36r抗体 |
DK2817338T3 (en) | 2012-02-24 | 2017-10-23 | Abbvie Stemcentrx Llc | DLL3 modulators and methods of use |
CN106103484B (zh) * | 2014-03-14 | 2021-08-20 | 诺华股份有限公司 | 针对lag-3的抗体分子及其用途 |
RU2582569C2 (ru) * | 2014-07-24 | 2016-04-27 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт особо чистых биопрепаратов" Федерального медико-биологического агентства | Днк, кодирующая полноразмерный антагонист рецептора интерлейкина-36 человека, днк, кодирующая полноразмерный антагонист рецептора интерлейкина-36 человека с с-концевым полигистидиновым тагом, плазмидный экспрессионный вектор (варианты), штамм бактерий escherichia coli bl21 star[de3] (рет-il36raf), - продуцент полноразмерного рецепторного антагониста интерлейкина-36 и штамм бактерий escherichia coli bl21 star[de3] (pet-il36raf-his), - продуцент полноразмерного рецепторного антагониста интерлейкина-36 с с-концевым полигистидиновым тагом |
MA41867A (fr) | 2015-04-01 | 2018-02-06 | Anaptysbio Inc | Anticorps dirigés contre l'immunoglobuline de cellule t et protéine 3 de mucine (tim-3) |
WO2016168542A1 (en) | 2015-04-15 | 2016-10-20 | Anaptysbio, Inc. | Antibodies directed against interleukin 36 receptor (il-36r) |
US10723793B2 (en) * | 2015-06-12 | 2020-07-28 | Ludwig Institute For Cancer Research, Ltd. | TGF-β3 specific antibodies and methods and uses thereof |
JP6654773B2 (ja) * | 2015-12-25 | 2020-02-26 | 国立大学法人名古屋大学 | インターロイキン36受容体アンタゴニスト欠損症の治療薬 |
MA50677A (fr) | 2016-11-01 | 2021-07-14 | Anaptysbio Inc | Anticorps dirigés contre la protéine d'immunoglobuline de lymphocytes t et mucine 3 (tim-3) |
MA47206A (fr) | 2017-01-09 | 2019-11-13 | Tesaro Inc | Méthodes de traitement du cancer au moyen d'anticorps anti-tim-3 |
CN110461877A (zh) * | 2017-03-27 | 2019-11-15 | 勃林格殷格翰国际有限公司 | 抗il-36r抗体联合治疗 |
AU2019205786B2 (en) * | 2018-01-08 | 2023-12-14 | Chemocentryx, Inc. | Methods of treating generalized pustular psoriasis with an antagonist of CCR6 or CXCR2 |
CA3090421A1 (en) * | 2018-03-14 | 2019-09-19 | Boehringer Ingelheim International Gmbh | Use of anti-il-36r antibodies for treatment of inflammatory bowel disease |
KR20200131871A (ko) * | 2018-03-14 | 2020-11-24 | 베링거 인겔하임 인터내셔날 게엠베하 | 전신성 농포 건선의 치료를 위한 항-il-36r 항체의 용도 |
WO2020018503A2 (en) * | 2018-07-16 | 2020-01-23 | Regeneron Pharmaceuticals, Inc. | Anti-il36r antibodies |
CN116200426A (zh) | 2018-07-16 | 2023-06-02 | 瑞泽恩制药公司 | Ditra疾病的非人动物模型及其用途 |
CN112638946A (zh) | 2018-08-16 | 2021-04-09 | 坎塔吉亚有限责任公司 | 抗il1rap抗体组合物 |
AU2019349958A1 (en) * | 2018-09-28 | 2021-05-06 | Kyowa Kirin Co., Ltd. | IL-36 antibodies and uses thereof |
JP2022514950A (ja) * | 2018-12-21 | 2022-02-16 | 23アンドミー・インコーポレイテッド | 抗il-36抗体およびその使用方法 |
CA3124996A1 (en) | 2018-12-27 | 2020-07-02 | Boehringer Ingelheim International Gmbh | Il-36r antibodies for treatment of palmoplantar pustulosis |
JP7420827B2 (ja) | 2019-03-08 | 2024-01-23 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 抗il-36r抗体製剤 |
US20220162326A1 (en) * | 2019-05-13 | 2022-05-26 | Regeneron Pharmaceuticals, Inc. | Anti-il36r antibodies |
WO2021112196A1 (ja) * | 2019-12-05 | 2021-06-10 | 学校法人東京薬科大学 | 筋組織の減少を抑制するための組成物 |
AR120913A1 (es) * | 2019-12-27 | 2022-03-30 | Teijin Pharma Ltd | Anticuerpo que inhibe específicamente la señalización de il-36r |
JP2023526359A (ja) | 2020-05-19 | 2023-06-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | アトピー性皮膚炎の処置のための抗il-36r抗体 |
TW202225190A (zh) | 2020-07-17 | 2022-07-01 | 德商百靈佳殷格翰國際股份有限公司 | 用於治療嗜中性球性皮膚病之抗-il-36r抗體 |
EP4188441A1 (en) | 2020-07-30 | 2023-06-07 | AnaptysBio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for ichthyosis |
WO2022026829A1 (en) | 2020-07-30 | 2022-02-03 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for skin toxicity |
MX2023003723A (es) | 2020-09-30 | 2023-04-24 | Boehringer Ingelheim Int | Anticuerpos anti-il-36r para el tratamiento de dolor inflamatorio cronico. |
CN112094349B (zh) * | 2020-11-04 | 2021-02-09 | 上海华奥泰生物药业股份有限公司 | 靶向于白介素36r的抗体及其制备方法和应用 |
WO2022127842A1 (zh) * | 2020-12-17 | 2022-06-23 | 上海华奥泰生物药业股份有限公司 | 靶向il-17a和il-36r的双特异性抗体及其应用 |
WO2022150644A1 (en) | 2021-01-08 | 2022-07-14 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for acne |
US20240084021A1 (en) | 2021-01-08 | 2024-03-14 | Anaptysbio, Inc. | Anti-interleukin 36 receptor (il-36r) therapy for hidradenitis suppurativa |
WO2022166977A1 (zh) * | 2021-02-08 | 2022-08-11 | 上海普铭生物科技有限公司 | 抗人il-36r抗体及其应用 |
BR112023014103A2 (pt) | 2021-03-04 | 2023-10-10 | Boehringer Ingelheim Int | Métodos para o tratamento de gpp |
US20220290239A1 (en) | 2021-03-12 | 2022-09-15 | Boehringer Ingelheim International Gmbh | Biomarkers associated with anti-il-36r antibody treatment in generalized pustular psoriasis |
KR20240004718A (ko) * | 2021-05-03 | 2024-01-11 | 베링거 인겔하임 인터내셔날 게엠베하 | 스페솔리맙의 제조방법 |
EP4357361A1 (en) * | 2021-06-18 | 2024-04-24 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Anti-il-36r antibody and use thereof |
WO2023285362A1 (en) | 2021-07-12 | 2023-01-19 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of il-36 inhibitors for the treatment of netherton syndrome |
WO2023019232A1 (en) | 2021-08-13 | 2023-02-16 | Boehringer Ingelheim International Gmbh | Anti-il-36r antibodies for the treatment of a fibrotic condition |
WO2023052222A2 (en) | 2021-09-28 | 2023-04-06 | Boehringer Ingelheim International Gmbh | System and method for assessing severity of neutrophilic dermatoses with visible skin manifestation |
TW202334200A (zh) | 2021-10-28 | 2023-09-01 | 美商艾伯維有限公司 | 抗澱粉樣蛋白β抗體及其使用方法 |
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