PL2510096T5 - Modyfikacja DNA zależna od efektora TAL - Google Patents

Modyfikacja DNA zależna od efektora TAL

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Publication number
PL2510096T5
PL2510096T5 PL10799163T PL10799163T PL2510096T5 PL 2510096 T5 PL2510096 T5 PL 2510096T5 PL 10799163 T PL10799163 T PL 10799163T PL 10799163 T PL10799163 T PL 10799163T PL 2510096 T5 PL2510096 T5 PL 2510096T5
Authority
PL
Poland
Prior art keywords
mediated dna
tal effector
dna modification
modification
tal
Prior art date
Application number
PL10799163T
Other languages
English (en)
Other versions
PL2510096T3 (pl
Inventor
Daniel F. Voytas
Adam Bogdanove
Feng Zhang
Michelle Christian
Tomas Cermak
Clarice Lauer Schmidt
Erin Doyle
Li Wang
Original Assignee
Regents Of The University Of Minnesota
Iowa State University Research Foundation, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43825298&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2510096(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regents Of The University Of Minnesota, Iowa State University Research Foundation, Inc. filed Critical Regents Of The University Of Minnesota
Publication of PL2510096T3 publication Critical patent/PL2510096T3/pl
Publication of PL2510096T5 publication Critical patent/PL2510096T5/pl

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1082—Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • C12N2810/00—Vectors comprising a targeting moiety
    • C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
    • C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
    • C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
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    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/21—Endodeoxyribonucleases producing 5'-phosphomonoesters (3.1.21)
    • C12Y301/21004—Type II site-specific deoxyribonuclease (3.1.21.4)
PL10799163T 2009-12-10 2010-12-10 Modyfikacja DNA zależna od efektora TAL PL2510096T5 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US28532409P 2009-12-10 2009-12-10
US35210810P 2010-06-07 2010-06-07
US36668510P 2010-07-22 2010-07-22
PCT/US2010/059932 WO2011072246A2 (en) 2009-12-10 2010-12-10 Tal effector-mediated dna modification
EP10799163.0A EP2510096B2 (en) 2009-12-10 2010-12-10 Tal effector-mediated dna modification

Publications (2)

Publication Number Publication Date
PL2510096T3 PL2510096T3 (pl) 2015-07-31
PL2510096T5 true PL2510096T5 (pl) 2018-06-29

Family

ID=43825298

Family Applications (2)

Application Number Title Priority Date Filing Date
PL10799163T PL2510096T5 (pl) 2009-12-10 2010-12-10 Modyfikacja DNA zależna od efektora TAL
PL14183521T PL2816112T3 (pl) 2009-12-10 2010-12-10 Modyfikacja DNA za pośrednictwem efektorów TAL

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL14183521T PL2816112T3 (pl) 2009-12-10 2010-12-10 Modyfikacja DNA za pośrednictwem efektorów TAL

Country Status (19)

Country Link
US (10) US8586363B2 (pl)
EP (3) EP2816112B1 (pl)
JP (3) JP2013513389A (pl)
KR (2) KR102110608B1 (pl)
CN (2) CN102770539B (pl)
AU (2) AU2010327998B2 (pl)
BR (1) BR112012014080A2 (pl)
CA (1) CA2783351C (pl)
DK (2) DK2816112T3 (pl)
ES (2) ES2696825T3 (pl)
HK (1) HK1205527A1 (pl)
HU (1) HUE041436T2 (pl)
IL (2) IL220234B (pl)
NO (1) NO2510096T3 (pl)
PL (2) PL2510096T5 (pl)
PT (2) PT2510096E (pl)
SG (1) SG181601A1 (pl)
TR (1) TR201815882T4 (pl)
WO (1) WO2011072246A2 (pl)

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