PL1939204T6 - Skondensowana pochodna heterocykliczna, zawierająca ją kompozycja oraz jej zastosowanie medyczne - Google Patents

Skondensowana pochodna heterocykliczna, zawierająca ją kompozycja oraz jej zastosowanie medyczne

Info

Publication number
PL1939204T6
PL1939204T6 PL06811925.4T PL06811925T PL1939204T6 PL 1939204 T6 PL1939204 T6 PL 1939204T6 PL 06811925 T PL06811925 T PL 06811925T PL 1939204 T6 PL1939204 T6 PL 1939204T6
Authority
PL
Poland
Prior art keywords
medicinal
same
composition containing
fused heterocyclic
heterocyclic derivative
Prior art date
Application number
PL06811925.4T
Other languages
English (en)
Other versions
PL1939204T3 (pl
Inventor
Kohsuke Ohno
Takashi Miyagi
Tomonaga Ozawa
Nobuhiko Fushimi
Original Assignee
Kissei Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co., Ltd. filed Critical Kissei Pharmaceutical Co., Ltd.
Publication of PL1939204T3 publication Critical patent/PL1939204T3/pl
Publication of PL1939204T6 publication Critical patent/PL1939204T6/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28Antiandrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL06811925.4T 2005-10-19 2006-10-17 Skondensowana pochodna heterocykliczna, zawierająca ją kompozycja oraz jej zastosowanie medyczne PL1939204T6 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2005304395 2005-10-19
JP2006147019 2006-05-26
PCT/JP2006/320681 WO2007046392A1 (ja) 2005-10-19 2006-10-17 縮合複素環誘導体、それを含有する医薬組成物及びその医薬用途
EP06811925.4A EP1939204B3 (en) 2005-10-19 2006-10-17 Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof

Publications (2)

Publication Number Publication Date
PL1939204T3 PL1939204T3 (pl) 2013-06-28
PL1939204T6 true PL1939204T6 (pl) 2024-03-25

Family

ID=37962485

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06811925.4T PL1939204T6 (pl) 2005-10-19 2006-10-17 Skondensowana pochodna heterocykliczna, zawierająca ją kompozycja oraz jej zastosowanie medyczne

Country Status (21)

Country Link
US (1) US9040693B2 (pl)
EP (1) EP1939204B3 (pl)
JP (2) JP4955566B2 (pl)
KR (1) KR101384132B1 (pl)
AU (1) AU2006305271B2 (pl)
BR (1) BRPI0617436B8 (pl)
CA (1) CA2624492C (pl)
CY (1) CY1113898T1 (pl)
DK (1) DK1939204T6 (pl)
ES (1) ES2398917T7 (pl)
HK (1) HK1125110A1 (pl)
IL (1) IL190754A (pl)
NL (1) NL301202I2 (pl)
NO (1) NO343185B1 (pl)
NZ (1) NZ567300A (pl)
PL (1) PL1939204T6 (pl)
PT (1) PT1939204E (pl)
RU (1) RU2418803C2 (pl)
SI (1) SI1939204T1 (pl)
TW (1) TWI400074B (pl)
WO (1) WO2007046392A1 (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008124614A1 (en) * 2007-04-06 2008-10-16 Neurocrine Biosciences, Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
AR065948A1 (es) 2007-04-06 2009-07-15 Neurocrine Biosciences Inc Antagonistas del receptor de la hormona liberadora de gonadotropina y procedimientos relacionados con los mismos
JP5352449B2 (ja) * 2007-04-18 2013-11-27 キッセイ薬品工業株式会社 縮合へテロ環誘導体、それを含有する医薬組成物及びその医薬用途
CA2682400A1 (en) * 2007-04-18 2008-11-06 Kissei Pharmaceutical Co., Ltd. Fused heterocyclic derivative, pharmaceutical composition comprising the derivative, and use of the composition for medical purposes
CN102753557B (zh) 2010-02-10 2015-10-14 橘生药品工业株式会社 稠合杂环衍生物的盐及其晶体
US20150299188A1 (en) 2012-08-24 2015-10-22 Takeda Pharmaceutical Company Limited Heterocyclic compound
JP6268093B2 (ja) * 2012-09-14 2018-01-24 キッセイ薬品工業株式会社 縮合複素環誘導体の製造方法およびその製造中間体
US9771320B2 (en) * 2014-01-06 2017-09-26 Bristol-Myers Squibb Company Carbocyclic sulfone RORγ modulators
TWI746613B (zh) 2016-08-08 2021-11-21 日商橘生藥品工業股份有限公司 子宮內膜病症治療劑之用法及用量
HUE058207T2 (hu) * 2017-01-31 2022-07-28 Veru Inc Készítmények és módszerek gonadotropin felszabadító hormon (GNRH) antagonisták elnyújtott idejû felszabadítására
MX2019014482A (es) 2017-06-05 2020-08-17 ObsEva SA Régimenes de dosificación de antagonistas de hormona liberadora de gonadotropina para tratar miomas uterinos y reducir la menstruación.
MA49256A (fr) 2017-06-05 2021-05-26 ObsEva SA Schémas posologiques comprenant un antagoniste de l'hormone de libération des gonadotrophines pour le traitement de l'endométriose
EP3746429B1 (en) * 2018-01-30 2022-03-09 Incyte Corporation Processes for preparing (1-(3-fluoro-2-(trifluoromethyl)isonicotinyl)piperidine-4-one)
WO2020089190A2 (en) 2018-10-29 2020-05-07 ObsEva S.A. Compositions and methods for the treatment of adenomyosis and rectovaginal endometriosis
EP3876943A2 (en) 2018-11-07 2021-09-15 ObsEva S.A. Compositions and methods for the treatment of estrogen-dependent disorders
AU2020325721A1 (en) * 2019-08-08 2022-03-03 ObsEva S.A. GnRH antagonists for the treatment of estrogen-dependent disorders
WO2021023877A2 (en) 2019-08-08 2021-02-11 ObsEva S.A. Compositions and methods for the treatment of estrogen-dependent disorders
TWI796144B (zh) * 2021-02-23 2023-03-11 大陸商南京明德新藥研發有限公司 噻吩並嘧啶二酮類化合物及其應用
JP2024507408A (ja) * 2021-02-23 2024-02-19 ソーター・バイオファーマ・プライベイト・リミテッド 縮合多環式置換5-カルボン酸チエノピリミジンジオン化合物およびその使用
WO2024037532A1 (zh) * 2022-08-16 2024-02-22 深圳市康哲生物科技有限公司 一种噻吩并嘧啶酮衍生物的盐型及晶型

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2192283A1 (en) * 1995-12-08 1997-06-09 Nobuhiro Suzuki Prolactin production inhibitory agent
WO1997040846A1 (en) 1996-04-30 1997-11-06 Takeda Chemical Industries, Ltd. COMBINED USE OF GnRH AGONIST AND ANTAGONIST
CA2254769A1 (en) * 1996-05-20 1997-11-27 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone
GB0124627D0 (en) * 2001-10-15 2001-12-05 Smithkline Beecham Plc Novel compounds
US20070135454A1 (en) 2003-11-14 2007-06-14 Tracy Bayliss Bicyclic pyrimidin-4(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1-receptor(vr1)
JP2007514757A (ja) * 2003-12-19 2007-06-07 メルク エンド カムパニー インコーポレーテッド 有糸***キネシン阻害剤
US20090062258A1 (en) * 2005-02-03 2009-03-05 Takeda Pharmaceutical Company Limited Fused pyrimidine derivative and use thereof

Also Published As

Publication number Publication date
NZ567300A (en) 2010-11-26
CY1113898T1 (el) 2016-07-27
EP1939204B3 (en) 2022-08-24
IL190754A (en) 2012-10-31
DK1939204T3 (da) 2013-03-11
BRPI0617436A2 (pt) 2011-07-26
BRPI0617436B1 (pt) 2021-04-06
CA2624492C (en) 2014-02-18
NO343185B1 (no) 2018-11-26
US9040693B2 (en) 2015-05-26
JP4955566B2 (ja) 2012-06-20
NO20082249L (no) 2008-07-18
US20090325900A1 (en) 2009-12-31
JP5319797B2 (ja) 2013-10-16
IL190754A0 (en) 2008-11-03
ES2398917T7 (es) 2022-10-26
RU2418803C2 (ru) 2011-05-20
KR101384132B1 (ko) 2014-04-10
WO2007046392A1 (ja) 2007-04-26
EP1939204B1 (en) 2013-01-02
RU2008119462A (ru) 2009-11-27
EP1939204A4 (en) 2010-09-01
ES2398917T3 (es) 2013-03-22
DK1939204T6 (da) 2022-09-05
HK1125110A1 (en) 2009-07-31
TW200732309A (en) 2007-09-01
PT1939204E (pt) 2013-03-14
TWI400074B (zh) 2013-07-01
KR20080063827A (ko) 2008-07-07
CA2624492A1 (en) 2007-04-26
NL301202I1 (nl) 2022-11-09
NL301202I2 (nl) 2023-01-24
JPWO2007046392A1 (ja) 2009-04-23
AU2006305271A1 (en) 2007-04-26
AU2006305271B2 (en) 2011-11-17
BRPI0617436B8 (pt) 2021-05-25
PL1939204T3 (pl) 2013-06-28
EP1939204A1 (en) 2008-07-02
SI1939204T1 (sl) 2013-05-31
JP2012102140A (ja) 2012-05-31

Similar Documents

Publication Publication Date Title
HK1099556A1 (en) Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof
HK1125110A1 (en) Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof
ZA200608028B (en) Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof
IL191623A0 (en) Fused heterocyclic compounds and pharmaceutical compositions containing the same
IL192184A0 (en) Heterocyclic derivatives and pharmaceutical compositions containing the same
EP1885369A4 (en) FUSED HETEROCYCLIC COMPOUNDS, COMPOSITIONS THEREOF AND USES THEREOF
IL191141A0 (en) Heterocyclic compounds and pharmaceutical compositions containing the same
IL186665A0 (en) Heterocyclic compounds and pharmaceutical compositions containing the same
IL187434A0 (en) Heterocyclic compounds and pharmaceutical compositions containing the same
IL192298A (en) Heterocyclic Compounds, Their Acceptable Salts, Pharmaceuticals Containing and Using Them
EP1932833A4 (en) NITROGENATED HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF
IL225206A (en) A derivative of multinuclear carbamoylpyridone, its pharmaceutical composition and its use
IL187163A0 (en) Novel fluorene derivatives, composition containing said derivatives and the use thereof
IL188941A0 (en) Pyrazinolyguanidine derivatives and pharmaceutical compositions containing the same
IL186738A0 (en) Pyrizole derivatives and pharmaceutical compositions containing the same
IL189782A (en) The history of sulfonylpyrol and its medicinal products and their use
IL189697A0 (en) Pyridazinone derivatives and pharmaceutical compositions containing the same
IL183919A0 (en) Triazolophthalazine derivatives and pharmaceutical compositions containing the same
IL177168A0 (en) N-sulphonylpyrrole derivatives and pharmaceutical compositions containing the same
IL221323A0 (en) 1-methyl-1h- pyridin-2-one- phenanthridine derivatives and pharmaceutical compositions containing the same
IL187603A0 (en) Piperazine derivatives and pharmaceutical compositions containing the same
IL187534A0 (en) Thiazole derivatives, use thereof and pharmaceutical compositions containing them
IL184996A0 (en) Dihydroimidazothiazole derivatives and pharmaceutical compositions containing the same
PL394604A1 (pl) Pochodna winyloazacykloalkanowa, jej zastosowanie oraz kompozycja farmaceutyczna
IL181730A0 (en) Benzodiazinone derivatives and pharmaceutical compositions containing the same