PL1922309T3 - Pochodne n-fenylo-2-pirymidynoaminy oraz sposób ich otrzymywania - Google Patents
Pochodne n-fenylo-2-pirymidynoaminy oraz sposób ich otrzymywaniaInfo
- Publication number
- PL1922309T3 PL1922309T3 PL05808814T PL05808814T PL1922309T3 PL 1922309 T3 PL1922309 T3 PL 1922309T3 PL 05808814 T PL05808814 T PL 05808814T PL 05808814 T PL05808814 T PL 05808814T PL 1922309 T3 PL1922309 T3 PL 1922309T3
- Authority
- PL
- Poland
- Prior art keywords
- pyrimidine
- phenyl
- preparation
- amine derivatives
- amine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020050071656A KR100674813B1 (ko) | 2005-08-05 | 2005-08-05 | Ｎ-페닐-2-피리미딘-아민 유도체 및 그의 제조방법 |
| EP05808814.7A EP1922309B1 (en) | 2005-08-05 | 2005-09-07 | N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof |
| PCT/KR2005/002962 WO2007018325A1 (en) | 2005-08-05 | 2005-09-07 | N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1922309T3 true PL1922309T3 (pl) | 2014-11-28 |
Family
ID=37727490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05808814T PL1922309T3 (pl) | 2005-08-05 | 2005-09-07 | Pochodne n-fenylo-2-pirymidynoaminy oraz sposób ich otrzymywania |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7501424B2 (pl) |
| EP (1) | EP1922309B1 (pl) |
| JP (1) | JP5094721B2 (pl) |
| KR (1) | KR100674813B1 (pl) |
| CN (1) | CN101155786B (pl) |
| AU (1) | AU2005335298C1 (pl) |
| CA (1) | CA2617991C (pl) |
| DK (1) | DK1922309T3 (pl) |
| EA (1) | EA015103B1 (pl) |
| ES (1) | ES2493627T3 (pl) |
| MX (1) | MX2008001221A (pl) |
| NZ (1) | NZ564908A (pl) |
| PL (1) | PL1922309T3 (pl) |
| PT (1) | PT1922309E (pl) |
| RS (1) | RS53379B (pl) |
| WO (1) | WO2007018325A1 (pl) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100654039B1 (ko) | 2005-11-14 | 2006-12-05 | 에스케이 텔레콤주식회사 | 무선 인터넷에서 서비스 서버의 인증방법 및 이를 이용한결제방법 |
| EP2684874B1 (en) | 2006-10-23 | 2017-05-17 | Cephalon, Inc. | Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and C-met inhibitors |
| RU2009120882A (ru) * | 2006-11-03 | 2010-12-10 | Айрм Ллк (Bm) | Соединения и композиции, как ингибиторы протеинкиназы |
| CA2686382C (en) * | 2007-05-04 | 2013-09-17 | Irm Llc | Phenylaminopyrimidine derivatives and compositions thereof as c-kit and pdgfr kinase inhibitors |
| ES2381318T3 (es) * | 2007-05-04 | 2012-05-25 | Irm Llc | Derivados de pirimidina y composiciones útiles como inhibidores de cinasas C-KIT y PDGFR |
| EP2152079A4 (en) | 2007-06-04 | 2011-03-09 | Avila Therapeutics Inc | HETEROCYCLIC COMPOUNDS AND USES THEREOF |
| KR101171488B1 (ko) | 2007-08-22 | 2012-08-07 | 아이알엠 엘엘씨 | 키나제 억제제로서의 2-헤테로아릴아미노-피리미딘 유도체 |
| EP2305667A3 (en) | 2008-07-17 | 2011-05-11 | Teva Pharmaceutical Industries Ltd. | Nilotinib intermediates and preparation thereof |
| KR20100021321A (ko) * | 2008-08-14 | 2010-02-24 | 일양약품주식회사 | Ν-페닐-2-피리미딘-아민 유도체의 제조방법 |
| EP2262793B1 (en) | 2008-11-05 | 2012-10-03 | Teva Pharmaceutical Industries Ltd. | Nilotinib hci crystalline forms |
| WO2010060074A1 (en) * | 2008-11-24 | 2010-05-27 | Teva Pharmaceutical Industries Ltd. | Preparation of nilotinib and intermediates thereof |
| CA2798578C (en) | 2010-05-21 | 2015-12-29 | Chemilia Ab | Novel pyrimidine derivatives |
| CA2830129C (en) | 2011-03-24 | 2016-07-19 | Chemilia Ab | Novel pyrimidine derivatives |
| KR101369584B1 (ko) | 2011-04-19 | 2014-03-06 | 일양약품주식회사 | 페닐-이속사졸 유도체 및 그의 제조방법 |
| RU2486180C1 (ru) * | 2011-11-02 | 2013-06-27 | Общество с ограниченной ответственностью "ТехноХим" (ООО "ТехноХим") | Способ получения 2-ариламино-4-гетарилпиримидинов |
| KR101956586B1 (ko) * | 2012-03-27 | 2019-03-11 | 일양약품주식회사 | 약제학적 조성물 및 이의 제조방법 |
| JP5910311B2 (ja) * | 2012-05-23 | 2016-04-27 | ニプロ株式会社 | 医薬錠剤およびその製造方法 |
| CN104940748A (zh) * | 2015-06-09 | 2015-09-30 | 林正兴 | 一种治疗胃癌的药物组合物 |
| EP3609882B1 (en) | 2017-03-17 | 2022-07-13 | Cardio Therapeutics Pty Ltd | Heterocyclic inhibitors of pcsk9 |
| CN107056713A (zh) * | 2017-05-18 | 2017-08-18 | 厦门大学 | 4‑((4‑取代芳基‑2‑嘧啶基)氨基)苯甲酰肼衍生物及其制备方法和应用 |
| CN111039932B (zh) * | 2019-12-13 | 2023-09-12 | 安徽峆一药业股份有限公司 | 一种拉多替尼的高收率合成方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CO4940418A1 (es) | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
| US6368651B1 (en) | 1999-05-13 | 2002-04-09 | The Nutrasweet Company | Use of additives to modify the taste characteristics of N-neohexyl-α-aspartyl-L-phenylalanine methyl ester |
| AU7322100A (en) | 1999-10-04 | 2001-05-10 | Ajinomoto Co., Inc. | Sweetener compositions with high degree of sweetness having improved sweetness, corrigents and utilization thereof |
| GB0021726D0 (en) * | 2000-09-05 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
| GB0022438D0 (en) * | 2000-09-13 | 2000-11-01 | Novartis Ag | Organic Compounds |
| DK1330452T3 (da) * | 2000-09-20 | 2009-03-16 | Ortho Mcneil Janssen Pharm | Pyrazinderivater som modulatorer af tyrosinkinaser |
| US7129242B2 (en) * | 2000-12-06 | 2006-10-31 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto |
| WO2002096905A1 (en) * | 2001-06-01 | 2002-12-05 | Vertex Pharmaceuticals Incorporated | Thiazole compounds useful as inhibitors of protein kinases |
| US6958340B2 (en) * | 2001-08-01 | 2005-10-25 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| JP4552650B2 (ja) * | 2002-06-28 | 2010-09-29 | 日本新薬株式会社 | アミド誘導体及び医薬 |
| GB0215676D0 (en) * | 2002-07-05 | 2002-08-14 | Novartis Ag | Organic compounds |
| ATE396731T1 (de) * | 2003-03-25 | 2008-06-15 | Vertex Pharma | Thiazole zur verwendung als inhibitoren von protein-kinasen |
| US20040235834A1 (en) * | 2003-03-25 | 2004-11-25 | Farmer Luc J. | Thiazoles useful as inhibitors of protein kinases |
| AU2003232650A1 (en) | 2003-05-06 | 2004-11-26 | Il Yang Pharm Co., Ltd. | N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof |
| CA2529090A1 (en) * | 2003-06-13 | 2004-12-23 | Novartis Ag | 2-aminopyrimidine derivatives as raf kinase inhibitors |
| DK1702917T3 (da) * | 2003-12-25 | 2017-11-13 | Nippon Shinyaku Co Ltd | Amidderivat og medicin |
| JPWO2005063720A1 (ja) * | 2003-12-25 | 2007-07-19 | 日本新薬株式会社 | アミド誘導体及び医薬 |
| WO2005113550A1 (ja) * | 2004-05-20 | 2005-12-01 | Mitsubishi Pharma Corporation | アミノピリミジン誘導体及びその医薬としての用途 |
-
2005
- 2005-08-05 KR KR1020050071656A patent/KR100674813B1/ko active Protection Beyond IP Right Term
- 2005-09-07 US US11/813,175 patent/US7501424B2/en active Active
- 2005-09-07 EA EA200800516A patent/EA015103B1/ru not_active IP Right Cessation
- 2005-09-07 CA CA2617991A patent/CA2617991C/en active Active
- 2005-09-07 DK DK05808814.7T patent/DK1922309T3/da active
- 2005-09-07 MX MX2008001221A patent/MX2008001221A/es active IP Right Grant
- 2005-09-07 PT PT58088147T patent/PT1922309E/pt unknown
- 2005-09-07 RS RS20080002A patent/RS53379B/en unknown
- 2005-09-07 ES ES05808814.7T patent/ES2493627T3/es active Active
- 2005-09-07 AU AU2005335298A patent/AU2005335298C1/en active Active
- 2005-09-07 PL PL05808814T patent/PL1922309T3/pl unknown
- 2005-09-07 CN CN2005800454145A patent/CN101155786B/zh active Active
- 2005-09-07 NZ NZ564908A patent/NZ564908A/en unknown
- 2005-09-07 EP EP05808814.7A patent/EP1922309B1/en active Active
- 2005-09-07 JP JP2008524874A patent/JP5094721B2/ja active Active
- 2005-09-07 WO PCT/KR2005/002962 patent/WO2007018325A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| RS20080002A (en) | 2009-07-15 |
| WO2007018325A1 (en) | 2007-02-15 |
| AU2005335298C1 (en) | 2010-11-25 |
| US7501424B2 (en) | 2009-03-10 |
| ES2493627T3 (es) | 2014-09-12 |
| AU2005335298B2 (en) | 2010-05-27 |
| US20080096899A1 (en) | 2008-04-24 |
| EP1922309A1 (en) | 2008-05-21 |
| DK1922309T3 (da) | 2014-08-25 |
| JP5094721B2 (ja) | 2012-12-12 |
| EA015103B1 (ru) | 2011-06-30 |
| KR100674813B1 (ko) | 2007-01-29 |
| EP1922309B1 (en) | 2014-05-21 |
| CA2617991A1 (en) | 2007-02-15 |
| RS53379B (en) | 2014-10-31 |
| MX2008001221A (es) | 2009-02-24 |
| CA2617991C (en) | 2011-08-09 |
| NZ564908A (en) | 2011-02-25 |
| EP1922309A4 (en) | 2009-10-14 |
| CN101155786B (zh) | 2012-08-29 |
| CN101155786A (zh) | 2008-04-02 |
| AU2005335298A1 (en) | 2007-02-15 |
| JP2009503060A (ja) | 2009-01-29 |
| EA200800516A1 (ru) | 2008-08-29 |
| PT1922309E (pt) | 2014-09-02 |
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