PE20091331A1 - Composiciones farmaceuticas que comprenden polimeros de amina reticulada - Google Patents
Composiciones farmaceuticas que comprenden polimeros de amina reticuladaInfo
- Publication number
- PE20091331A1 PE20091331A1 PE2008002075A PE2008002075A PE20091331A1 PE 20091331 A1 PE20091331 A1 PE 20091331A1 PE 2008002075 A PE2008002075 A PE 2008002075A PE 2008002075 A PE2008002075 A PE 2008002075A PE 20091331 A1 PE20091331 A1 PE 20091331A1
- Authority
- PE
- Peru
- Prior art keywords
- pharmaceutical compositions
- compositions including
- amine polymers
- reticulated
- including crosslink
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/08—Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/12—Macromolecular compounds
- B01J41/14—Macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
REFERIDA A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE UN POLIMERO DE AMINA RETICULADA QUE COMPRENDE UNIDADES DE REPETICION REPRESENTADAS POR LAS FORMULAS I Y/O II Y UN AGENTE RETICULANTE O UN RESIDUO DEL MISMO, DONDE m ES UN ENTERO DE 0 A 2, n ES UN NUMERO ENTERO, R1, R2, Y R3 SON H, ALQUILO C1-C6, ALQUILAMINO C1-C6, X- ES UN CONTRAION TAL COMO CARBONATO, BICARBONATO, CLORHIDRATO, ENTRE OTROS. EL POLIMERO DE AMINA RETICULADA TIENE UN VALOR DE ALANINA DE ENTRE 0,6 A 0,75 ppm, UN pH de ENTRE 9,3 A 9,7 Y UN PORCENTAJE DE OLIGOMEROS SOLUBLES MENOR A 0.1%. TAMBIEN ESTA REFERIDA A UN COMPRIMIDO QUE CONTIENE LA COMPOSICION Y A UN METODO DE PREPARACION
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US601907P | 2007-12-14 | 2007-12-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20091331A1 true PE20091331A1 (es) | 2009-09-18 |
Family
ID=40753579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2008002075A PE20091331A1 (es) | 2007-12-14 | 2008-12-12 | Composiciones farmaceuticas que comprenden polimeros de amina reticulada |
Country Status (9)
Country | Link |
---|---|
US (4) | US20090155368A1 (es) |
EP (1) | EP2222313A4 (es) |
JP (1) | JP2011506448A (es) |
AR (1) | AR072652A1 (es) |
PA (1) | PA8807201A1 (es) |
PE (1) | PE20091331A1 (es) |
TW (1) | TW200930384A (es) |
UY (1) | UY31530A (es) |
WO (1) | WO2009078956A1 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009154747A1 (en) * | 2008-06-20 | 2009-12-23 | Genzyme Corporation | Pharmaceutical compositions |
EP2773329B1 (en) * | 2011-11-04 | 2016-01-13 | Synthon BV | Pharmaceutical compositions comprising sevelamer |
WO2013087237A1 (en) * | 2011-12-13 | 2013-06-20 | Synthon Bv | Purification of sevelamer and related polyallylamines |
RU2014128587A (ru) * | 2011-12-13 | 2016-02-10 | Синтон Б.В. | Получение севеламера с пониженным содержанием аллиламина |
CN102895204B (zh) * | 2012-11-08 | 2014-12-31 | 南京生命能科技开发有限公司 | 一种用于制备片剂的碳酸司维拉姆原料药及其制备方法和应用 |
CN103864972A (zh) * | 2012-12-10 | 2014-06-18 | 天津泰普药品科技发展有限公司 | 一种碳酸司维拉姆的制备方法 |
US9566299B2 (en) * | 2013-02-08 | 2017-02-14 | Wockhardt Limited | Oral pharmaceutical composition of aliphatic amine polymer or salts thereof |
EP3578185B1 (en) | 2013-06-05 | 2020-08-05 | Tricida Inc. | Proton-binding polymers for oral administration |
BR112017011838B1 (pt) | 2014-12-10 | 2023-04-25 | Tricida, Inc | Polímeros de ligação a prótons para administração oral |
MA41202A (fr) * | 2014-12-18 | 2017-10-24 | Genzyme Corp | Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 |
SG11201809605PA (en) | 2016-05-06 | 2018-11-29 | Tricida Inc | Compositions for and method of treating acid-base disorders |
CA3039062A1 (en) | 2016-10-20 | 2018-04-26 | Colgate-Palmolive Company | Antimicrobial compositions for oral care or cleansing, and methods for anti-attachment polymers and coatings |
KR101853260B1 (ko) * | 2016-11-29 | 2018-06-14 | 주식회사 퍼슨 | 세벨라머 카보네이트의 제조방법 |
JP6792640B2 (ja) | 2016-12-28 | 2020-11-25 | 富士フイルム株式会社 | 窒素原子含有ポリマー又はその塩の乳化液、その製造方法、及び粒子の製造方法 |
TW201922267A (zh) * | 2017-10-16 | 2019-06-16 | 日商富士軟片股份有限公司 | 高磷血症治療劑 |
TW201922268A (zh) * | 2017-10-16 | 2019-06-16 | 日商富士軟片股份有限公司 | 高磷血症治療劑及粒子 |
EP3703706A4 (en) | 2017-11-03 | 2022-04-27 | Tricida Inc. | COMPOSITIONS AND METHOD FOR TREATING ACID-BASE DISORDERS |
CN109125273B (zh) * | 2018-09-28 | 2020-10-09 | 北京市中关村医院 | 一种磷结合剂及其制备方法和用途 |
CN112972407A (zh) * | 2019-12-18 | 2021-06-18 | 南京恒生制药有限公司 | 一种碳酸司维拉姆片剂组合物及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW474813B (en) * | 1994-06-10 | 2002-02-01 | Geltex Pharma Inc | Alkylated composition for removing bile salts from a patient |
US6423754B1 (en) * | 1997-06-18 | 2002-07-23 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with polyallylamine polymers |
TW568788B (en) * | 1998-10-12 | 2004-01-01 | Chugai Pharmaceutical Co Ltd | Polymer combining with phosphoric acid and preparation containing the same |
US7608674B2 (en) * | 2003-11-03 | 2009-10-27 | Ilypsa, Inc. | Pharmaceutical compositions comprising cross-linked small molecule amine polymers |
HUE026628T2 (en) * | 2005-09-15 | 2016-06-28 | Genzyme Corp | Pouches for amine polymers |
-
2008
- 2008-12-11 PA PA20088807201A patent/PA8807201A1/es unknown
- 2008-12-12 EP EP08863216A patent/EP2222313A4/en not_active Withdrawn
- 2008-12-12 AR ARP080105441A patent/AR072652A1/es unknown
- 2008-12-12 WO PCT/US2008/013673 patent/WO2009078956A1/en active Application Filing
- 2008-12-12 PE PE2008002075A patent/PE20091331A1/es not_active Application Discontinuation
- 2008-12-12 JP JP2010537975A patent/JP2011506448A/ja active Pending
- 2008-12-12 TW TW097148552A patent/TW200930384A/zh unknown
- 2008-12-12 US US12/314,554 patent/US20090155368A1/en not_active Abandoned
- 2008-12-12 UY UY0001031530A patent/UY31530A/es not_active Application Discontinuation
-
2014
- 2014-04-17 US US14/255,368 patent/US20140322319A1/en not_active Abandoned
-
2015
- 2015-12-14 US US14/968,170 patent/US20160158275A1/en not_active Abandoned
-
2019
- 2019-02-04 US US16/267,238 patent/US20190240252A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2222313A1 (en) | 2010-09-01 |
PA8807201A1 (es) | 2009-07-23 |
US20190240252A1 (en) | 2019-08-08 |
JP2011506448A (ja) | 2011-03-03 |
US20140322319A1 (en) | 2014-10-30 |
WO2009078956A1 (en) | 2009-06-25 |
UY31530A (es) | 2009-12-14 |
US20090155368A1 (en) | 2009-06-18 |
AR072652A1 (es) | 2010-09-15 |
US20160158275A1 (en) | 2016-06-09 |
TW200930384A (en) | 2009-07-16 |
EP2222313A4 (en) | 2011-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application declared void or lapsed |