PE20081635A1 - Agentes para suprimir la reaccion de rechazo cronica - Google Patents

Agentes para suprimir la reaccion de rechazo cronica

Info

Publication number
PE20081635A1
PE20081635A1 PE2008000168A PE2008000168A PE20081635A1 PE 20081635 A1 PE20081635 A1 PE 20081635A1 PE 2008000168 A PE2008000168 A PE 2008000168A PE 2008000168 A PE2008000168 A PE 2008000168A PE 20081635 A1 PE20081635 A1 PE 20081635A1
Authority
PE
Peru
Prior art keywords
suppress
chronic rejection
rejection reaction
agents
antibody
Prior art date
Application number
PE2008000168A
Other languages
English (en)
Inventor
Masafumi Takahashi
Atsushi Izawa
Original Assignee
Chugai Pharmaceutical Co Ltd
Univ Shinshu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd, Univ Shinshu filed Critical Chugai Pharmaceutical Co Ltd
Publication of PE20081635A1 publication Critical patent/PE20081635A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

SE REFIERE A UN AGENTE PARA SUPRIMIR LA REACCION DE RECHAZO CRONICA ESPECIALMENTE EN TRANSPLANTES DE CORAZON QUE TIENE COMO COMPONENTE ACTIVO UN INHIBIDOR DE LA IL-6 O FACTOR ESTIMULANTE DE LINFOCITOS B2 (BSF2) QUE ES UN ANTICUERPO MONOCLONAL HUMANIZADO RECOMBINANTE QUE RECONOCE A LA IL-6 HUMANA O AL RECEPTOR DE IL-6 HUMANO. SE REFIERE TAMBIEN A UN METODO DE TRATAMIENTO QUE CONSISTE EN ADMINISTRAR DICHO ANTICUERPO
PE2008000168A 2007-01-23 2008-01-23 Agentes para suprimir la reaccion de rechazo cronica PE20081635A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007012572 2007-01-23

Publications (1)

Publication Number Publication Date
PE20081635A1 true PE20081635A1 (es) 2009-01-07

Family

ID=39644475

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2008000168A PE20081635A1 (es) 2007-01-23 2008-01-23 Agentes para suprimir la reaccion de rechazo cronica

Country Status (17)

Country Link
US (1) US9725514B2 (es)
EP (1) EP2123302B1 (es)
JP (1) JP5254807B2 (es)
KR (1) KR101508019B1 (es)
CN (1) CN101646459B (es)
AR (1) AR065004A1 (es)
AU (1) AU2008208321B2 (es)
BR (1) BRPI0806812B8 (es)
CA (1) CA2675625C (es)
CL (1) CL2008000188A1 (es)
ES (1) ES2564392T3 (es)
HK (1) HK1140134A1 (es)
MX (1) MX2009007830A (es)
PE (1) PE20081635A1 (es)
RU (1) RU2450829C2 (es)
TW (1) TWI438208B (es)
WO (1) WO2008090901A1 (es)

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JP6442404B2 (ja) 2013-06-11 2018-12-19 国立研究開発法人国立精神・神経医療研究センター 再発寛解型多発性硬化症（ｒｒｍｓ）患者の治療予後予測方法、及び新規治療適応判断方法
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TW202339800A (zh) 2015-02-27 2023-10-16 日商中外製藥股份有限公司 Il-6受體抗體用於製備醫藥組成物的用途
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US11484591B2 (en) 2016-02-22 2022-11-01 Ohio State Innovation Foundation Chemoprevention using controlled-release formulations of anti-interleukin 6 agents, synthetic vitamin A analogues or metabolites, and estradiol metabolites
AU2018234844B2 (en) 2017-03-17 2024-01-25 Ohio State Innovation Foundation Nanoparticles for delivery of chemopreventive agents
JP7185884B2 (ja) 2017-05-02 2022-12-08 国立研究開発法人国立精神・神経医療研究センター Ｉｌ－６及び好中球の関連する疾患の治療効果の予測及び判定方法
KR20200074160A (ko) 2017-10-20 2020-06-24 가꼬우호우징 효고 이카다이가쿠 항il-6 수용체 항체를 함유하는 수술 후의 유착을 억제하기 위한 의약 조성물
WO2020201362A2 (en) 2019-04-02 2020-10-08 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of predicting and preventing cancer in patients having premalignant lesions

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