PE20020793A1 - Agente preventivo y/o terapeutico de enfermedades inflamatorias del tracto respiratorio - Google Patents

Agente preventivo y/o terapeutico de enfermedades inflamatorias del tracto respiratorio

Info

Publication number
PE20020793A1
PE20020793A1 PE2001001303A PE2001001303A PE20020793A1 PE 20020793 A1 PE20020793 A1 PE 20020793A1 PE 2001001303 A PE2001001303 A PE 2001001303A PE 2001001303 A PE2001001303 A PE 2001001303A PE 20020793 A1 PE20020793 A1 PE 20020793A1
Authority
PE
Peru
Prior art keywords
inflammatory diseases
respiratory tract
preventive
therapeutic agent
cyclopropanocarboxylate
Prior art date
Application number
PE2001001303A
Other languages
English (en)
Inventor
Teruo Komoto
Hiroyuki Mizuno
Koichi Takahashi
Yoshinori Takahashi
Susumu Sato
Original Assignee
Hisamitsu Medical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Medical Co Ltd filed Critical Hisamitsu Medical Co Ltd
Publication of PE20020793A1 publication Critical patent/PE20020793A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE AL USO DE DERIVADOS ESTEROIDES TAL COMO 9-FLUOR-11ß,17,21-TRIHIDROXI-16O-METIL-1,4-PREGNADIEN-3,20-DIONA; 17-CICLOPROPANOCARBOXILATO; 9-FLUOR-11ß,17,21-TRIHIDROXI-16O-METIL-1,4-PREGNADIEN-3,20-DIONA, 21-CICLOHEXANOCARBOXILATO, 17 CICLOPROPANOCARBOXILATO. LA FORMA FARMACEUTICA ES UNA COMPOSICION LIQUIDA O EN POLVO PARA INHALACION ORAL O ADMINISTRACION INTRANASAL. LOS COMPUESTOS INHIBEN LA INFLAMACION DE LOS CONDUCTOS RESPIRATORIOS Y PUEDEN SER UTILES PARA EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS DEL TRACTO RESPIRATORIO TAL COMO ASMA, HIPERSENSIBILIDAD, NASAL, ALERGIA, LARINGEA, SINUSITIS
PE2001001303A 2000-12-22 2001-12-26 Agente preventivo y/o terapeutico de enfermedades inflamatorias del tracto respiratorio PE20020793A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000390941 2000-12-22

Publications (1)

Publication Number Publication Date
PE20020793A1 true PE20020793A1 (es) 2002-09-06

Family

ID=18857198

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2001001303A PE20020793A1 (es) 2000-12-22 2001-12-26 Agente preventivo y/o terapeutico de enfermedades inflamatorias del tracto respiratorio

Country Status (16)

Country Link
US (1) US7214672B2 (es)
EP (1) EP1344526B1 (es)
JP (1) JP3691487B2 (es)
KR (1) KR100833157B1 (es)
CN (2) CN1481246A (es)
AR (2) AR031969A1 (es)
AT (1) ATE396733T1 (es)
CA (1) CA2438799C (es)
DE (1) DE60134267D1 (es)
DK (1) DK1344526T3 (es)
ES (1) ES2305029T3 (es)
MX (1) MXPA03005660A (es)
PE (1) PE20020793A1 (es)
PT (1) PT1344526E (es)
TW (1) TWI290145B (es)
WO (1) WO2002051422A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7576001A (en) * 2000-08-05 2002-02-18 Glaxo Group Ltd 6.alpha., 9.alpha.-difluoro-17.alpha.-`(2-furanylcarboxyl) oxy]-11.beta.-hydroxy-16.alpha.-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid s-fluoromethyl ester as an anti-inflammatory agent
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6777399B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
EP1383786B1 (en) * 2001-04-30 2008-10-15 Glaxo Group Limited Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha
DE60227254D1 (de) * 2001-06-12 2008-08-07 Glaxo Group Ltd Neue anti inflammatorische 17.alpha.-heterozyklische ester von 17.beta.-carbothioat androstan derivativen
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
JP3691459B2 (ja) * 2002-06-14 2005-09-07 久光メディカル株式会社 粉末状吸入剤組成物
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
EP1645266A1 (en) * 2004-10-08 2006-04-12 Hisamitsu Medical Co., Ltd. Aqueous suspension for nasal drops
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639434A (en) * 1967-02-02 1972-02-01 Boots Pure Drug Co Ltd 17-acyloxysteroids and their manufacture
SE418294B (sv) * 1974-03-27 1981-05-18 Plurichemie Anstalt Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester
US4933168A (en) * 1975-05-27 1990-06-12 Syntex Pharmaceuticals International Limited Stable, crystalline flunisolide
IL66432A0 (en) * 1981-08-04 1982-12-31 Plurichemie Anstalt Process for the preparation of steroidal esters
JPH07116215B2 (ja) * 1989-04-19 1995-12-13 エスエス製薬株式会社 新規なステロイド化合物
PE44995A1 (es) 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias

Also Published As

Publication number Publication date
DE60134267D1 (de) 2008-07-10
ATE396733T1 (de) 2008-06-15
US7214672B2 (en) 2007-05-08
EP1344526B1 (en) 2008-05-28
JP3691487B2 (ja) 2005-09-07
US20040053904A1 (en) 2004-03-18
CA2438799A1 (en) 2002-07-04
DK1344526T3 (da) 2008-09-15
MXPA03005660A (es) 2004-12-03
KR100833157B1 (ko) 2008-05-28
CA2438799C (en) 2009-09-01
WO2002051422A1 (fr) 2002-07-04
AR097737A2 (es) 2016-04-13
CN101518537A (zh) 2009-09-02
EP1344526A1 (en) 2003-09-17
EP1344526A4 (en) 2005-03-16
JPWO2002051422A1 (ja) 2004-04-22
TWI290145B (en) 2007-11-21
CN1481246A (zh) 2004-03-10
PT1344526E (pt) 2008-06-18
KR20030064414A (ko) 2003-07-31
ES2305029T3 (es) 2008-11-01
AR031969A1 (es) 2003-10-08

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