PA8495901A1 - Hidroxiamidas de acidos 3-(arilsulfonilamino)-tetrahidropiran-3-carboxilicos. - Google Patents
Hidroxiamidas de acidos 3-(arilsulfonilamino)-tetrahidropiran-3-carboxilicos.Info
- Publication number
- PA8495901A1 PA8495901A1 PA20008495901A PA8495901A PA8495901A1 PA 8495901 A1 PA8495901 A1 PA 8495901A1 PA 20008495901 A PA20008495901 A PA 20008495901A PA 8495901 A PA8495901 A PA 8495901A PA 8495901 A1 PA8495901 A1 PA 8495901A1
- Authority
- PA
- Panama
- Prior art keywords
- tetrahidropiran
- hydroxiamides
- carboxilicos
- arilsulfonilamino
- acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
Abstract
UN COMPUESTO DE FORMULA 1 EN LA QUE R1,R2,R3,R4 Y Q SON COMO SE HAN DEFINIDO ANTES, QUE ES UTIL EN EL TRATAMIENTO DE LA ARTRITIS (INCLUYENDO OSTEOARTRITIS Y ARTRITIS REUMATOIDE), EL CANCER Y OTRAS ENFERMEDADES. ADEMAS, LOS COMPUESTOS DE LA PRESENTE INVENCION SE PUEDEN USAR EN TERAPIA DE COMBINACION CON FARMACOS ANTIINFLAMATORIOS NO ESTEROIDEOS (AINE) , INHIBIDORES DE LA COX-2 Y ANALGESICOS CONVENCIONALES, Y EN COMBINACION CON FARMACOS CITOTOXICOS COMO ADRIAMICINA, DAUNOMICINA, CISPLATINO, ETOPOSIDO, TAXOL, TAXOTERO Y OTROS ALCALOIDES, COMO VINCRISTINA, EN EL TRATAMIENTO DEL CANCER.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13653099P | 1999-05-28 | 1999-05-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
PA8495901A1 true PA8495901A1 (es) | 2002-08-26 |
Family
ID=22473239
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PA20008495901A PA8495901A1 (es) | 1999-05-28 | 2000-05-19 | Hidroxiamidas de acidos 3-(arilsulfonilamino)-tetrahidropiran-3-carboxilicos. |
Country Status (22)
Country | Link |
---|---|
US (1) | US6197810B1 (es) |
EP (1) | EP1181286B1 (es) |
JP (1) | JP3784645B2 (es) |
AT (1) | ATE254119T1 (es) |
AU (1) | AU4424000A (es) |
BR (1) | BR0011539A (es) |
CA (1) | CA2375524C (es) |
DE (1) | DE60006523T2 (es) |
DK (1) | DK1181286T3 (es) |
DZ (1) | DZ3046A1 (es) |
ES (1) | ES2208315T3 (es) |
GT (1) | GT200000079A (es) |
HN (1) | HN2000000074A (es) |
MA (1) | MA26738A1 (es) |
MX (1) | MXPA01012265A (es) |
PA (1) | PA8495901A1 (es) |
PE (1) | PE20010170A1 (es) |
PT (1) | PT1181286E (es) |
SV (1) | SV2001000086A (es) |
TN (1) | TNSN00111A1 (es) |
UY (1) | UY26167A1 (es) |
WO (1) | WO2000073295A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040122011A1 (en) * | 1998-12-23 | 2004-06-24 | Pharmacia Corporation | Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy |
WO2001070693A2 (en) | 2000-03-21 | 2001-09-27 | The Procter & Gamble Company | Difluorobutyric acid derivatives and their use as metalloprotease inhibitors |
PL357250A1 (en) * | 2000-03-21 | 2004-07-26 | The Procter & Gamble Company | Heterocyclic side chain containing metalloprotease inhibitors |
CA2404131A1 (en) | 2000-03-21 | 2001-09-27 | The Procter & Gamble Company | Heterocyclic side chain containing, n-substituted metalloprotease inhibitors |
US7019376B2 (en) * | 2000-08-11 | 2006-03-28 | Reflectivity, Inc | Micromirror array device with a small pitch size |
US20030045449A1 (en) * | 2001-08-15 | 2003-03-06 | Pfizer, Inc. | Pharmaceutical combinations for the treatment of neurodegenerative diseases |
GB0319069D0 (en) * | 2003-08-14 | 2003-09-17 | Glaxo Group Ltd | Therapeutically useful compounds |
US20050058611A1 (en) * | 2003-08-22 | 2005-03-17 | L'oreal | Preventing and/or combating collagen fiber degradation induced under conditions of natural exposure to sunlight |
PL2385938T3 (pl) | 2009-01-12 | 2015-07-31 | Pfizer Ltd | Pochodne sulfonamidu |
CA2804173C (en) | 2010-07-09 | 2015-01-13 | Pfizer Limited | Sulfonamide nav1.7 inhibitors |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5455258A (en) * | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
IL131042A (en) | 1997-02-03 | 2004-07-25 | Pfizer Prod Inc | Derivatives of arylsulfonamic acid hydroxyamic acid and medicinal preparations containing them |
PA8469501A1 (es) * | 1998-04-10 | 2000-09-29 | Pfizer Prod Inc | Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico |
-
2000
- 2000-05-15 CA CA002375524A patent/CA2375524C/en not_active Expired - Fee Related
- 2000-05-15 AT AT00925520T patent/ATE254119T1/de not_active IP Right Cessation
- 2000-05-15 MX MXPA01012265A patent/MXPA01012265A/es active IP Right Grant
- 2000-05-15 PT PT00925520T patent/PT1181286E/pt unknown
- 2000-05-15 WO PCT/IB2000/000647 patent/WO2000073295A1/en active IP Right Grant
- 2000-05-15 HN HN2000000074A patent/HN2000000074A/es unknown
- 2000-05-15 DE DE60006523T patent/DE60006523T2/de not_active Expired - Fee Related
- 2000-05-15 AU AU44240/00A patent/AU4424000A/en not_active Abandoned
- 2000-05-15 BR BR0011539-8A patent/BR0011539A/pt not_active IP Right Cessation
- 2000-05-15 JP JP2000621361A patent/JP3784645B2/ja not_active Expired - Fee Related
- 2000-05-15 DK DK00925520T patent/DK1181286T3/da active
- 2000-05-15 ES ES00925520T patent/ES2208315T3/es not_active Expired - Lifetime
- 2000-05-15 EP EP00925520A patent/EP1181286B1/en not_active Expired - Lifetime
- 2000-05-19 PA PA20008495901A patent/PA8495901A1/es unknown
- 2000-05-24 TN TNTNSN00111A patent/TNSN00111A1/fr unknown
- 2000-05-24 DZ DZ000090A patent/DZ3046A1/xx active
- 2000-05-24 MA MA25988A patent/MA26738A1/fr unknown
- 2000-05-25 GT GT200000079A patent/GT200000079A/es unknown
- 2000-05-26 PE PE2000000507A patent/PE20010170A1/es not_active Application Discontinuation
- 2000-05-26 US US09/579,059 patent/US6197810B1/en not_active Expired - Fee Related
- 2000-05-26 SV SV2000000086A patent/SV2001000086A/es not_active Application Discontinuation
- 2000-05-26 UY UY26167A patent/UY26167A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2375524A1 (en) | 2000-12-07 |
ATE254119T1 (de) | 2003-11-15 |
AU4424000A (en) | 2000-12-18 |
SV2001000086A (es) | 2001-11-08 |
DK1181286T3 (da) | 2004-02-16 |
JP3784645B2 (ja) | 2006-06-14 |
MXPA01012265A (es) | 2002-07-30 |
CA2375524C (en) | 2006-11-28 |
PE20010170A1 (es) | 2001-02-27 |
JP2003500485A (ja) | 2003-01-07 |
EP1181286B1 (en) | 2003-11-12 |
WO2000073295A1 (en) | 2000-12-07 |
DE60006523D1 (de) | 2003-12-18 |
BR0011539A (pt) | 2002-02-26 |
HN2000000074A (es) | 2001-02-02 |
TNSN00111A1 (fr) | 2002-05-30 |
UY26167A1 (es) | 2000-12-29 |
MA26738A1 (fr) | 2004-12-20 |
GT200000079A (es) | 2001-11-16 |
DE60006523T2 (de) | 2004-08-12 |
ES2208315T3 (es) | 2004-06-16 |
US6197810B1 (en) | 2001-03-06 |
EP1181286A1 (en) | 2002-02-27 |
DZ3046A1 (fr) | 2004-03-27 |
PT1181286E (pt) | 2004-02-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PA8479901A1 (es) | Inhibidores de tace | |
YU5201A (sh) | Derivati hidroksipipekolathidroksamske kiseline kao inhibitori mmp | |
AP9801174A0 (en) | Cyclic sulfone derivatives. | |
TR200002951T2 (tr) | (4-Arilsülfonilamino)-tetrahidropiran-4-karboksilik asit hidroksamitler | |
MY121754A (en) | Arylsulfonylamino hydroxamic acid derivatives | |
EA199900641A1 (ru) | Производные арилсульфонилгидроксамовой кислоты | |
HN2000000074A (es) | Hidroxiamidas de acidos 3- (arilsulfonilamino)-tetrahidropiran-3-carboxilicos. | |
HN2000000052A (es) | Hidroxiamidas de acidos 3- (arilsulfonilamino)- tetrahidrofuran-3-carboxilicos. | |
ECSP003494A (es) | Hidroxiamidas de acidos 3- ( arilsulfonilamino)-tetrahidropiran-3-carboxilicos |