OA07282A - Composition pharmaceutique lyophilisée contenant de l'interféron procédé pour la préparation et procédé pour sa stabilisation. - Google Patents
Composition pharmaceutique lyophilisée contenant de l'interféron procédé pour la préparation et procédé pour sa stabilisation.Info
- Publication number
- OA07282A OA07282A OA57876A OA57876A OA07282A OA 07282 A OA07282 A OA 07282A OA 57876 A OA57876 A OA 57876A OA 57876 A OA57876 A OA 57876A OA 07282 A OA07282 A OA 07282A
- Authority
- OA
- OAPI
- Prior art keywords
- stabilization
- preparation
- pharmaceutical composition
- composition containing
- lyophilized pharmaceutical
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 102000014150 Interferons Human genes 0.000 title 1
- 108010050904 Interferons Proteins 0.000 title 1
- 229940079322 interferon Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33405281A | 1981-12-23 | 1981-12-23 | |
ZA828580A ZA828580B (en) | 1981-12-23 | 1982-11-19 | Interferon formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
OA07282A true OA07282A (fr) | 1984-11-30 |
Family
ID=26989028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA57876A OA07282A (fr) | 1981-12-23 | 1982-12-21 | Composition pharmaceutique lyophilisée contenant de l'interféron procédé pour la préparation et procédé pour sa stabilisation. |
Country Status (18)
Country | Link |
---|---|
US (1) | US4496537A (de) |
EP (1) | EP0082481B2 (de) |
AU (1) | AU558966B2 (de) |
CA (1) | CA1207665A (de) |
DE (1) | DE3262575D1 (de) |
DK (1) | DK158873C (de) |
FI (1) | FI70794C (de) |
HK (1) | HK94487A (de) |
HU (1) | HU190649B (de) |
IE (1) | IE54468B1 (de) |
IL (1) | IL67517A (de) |
MY (1) | MY8700705A (de) |
NO (1) | NO161036C (de) |
NZ (1) | NZ202856A (de) |
OA (1) | OA07282A (de) |
PH (1) | PH19869A (de) |
PT (1) | PT76013B (de) |
SG (1) | SG70687G (de) |
Families Citing this family (74)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4600583A (en) * | 1982-09-07 | 1986-07-15 | Tetra Consultants Inc. | Pharmaceutical compositions |
US4469228A (en) * | 1983-05-31 | 1984-09-04 | Schering Corporation | Interferon kit |
JPH0651641B2 (ja) * | 1983-08-29 | 1994-07-06 | 株式会社ミドリ十字 | ガンマ・インターフェロン組成物 |
JPS6034919A (ja) * | 1983-08-04 | 1985-02-22 | Green Cross Corp:The | ガンマ・インタ−フェロン組成物 |
US4855134A (en) * | 1983-10-14 | 1989-08-08 | Sumitomo Pharmaceuticals Company, Limited | Sustained-release preparation |
JPS60243028A (ja) * | 1984-04-28 | 1985-12-03 | Kyowa Hakko Kogyo Co Ltd | インタ−フエロンの可溶化方法 |
EP0168008A3 (de) * | 1984-07-10 | 1986-12-30 | Takeda Chemical Industries, Ltd. | Stabile Gamma-Interferonzusammensetzung |
US5196323A (en) * | 1985-04-27 | 1993-03-23 | Boehringer Ingelheim International Gmbh | Process for preparing and purifying alpha-interferon |
US4847079A (en) * | 1985-07-29 | 1989-07-11 | Schering Corporation | Biologically stable interferon compositions comprising thimerosal |
DE3628468A1 (de) * | 1986-08-21 | 1988-03-03 | Thomae Gmbh Dr K | Neue applikationsformen fuer (alpha)-interferone |
CA1320905C (en) * | 1986-11-06 | 1993-08-03 | Joseph M. Cummins | Treatment of immuno-resistant disease |
US4851220A (en) * | 1986-11-26 | 1989-07-25 | Schering Corporation | Stable oleaginous gel |
US4853218A (en) * | 1987-02-24 | 1989-08-01 | Schering Corporation | Zinc-protamine-alpha interferon complex |
US4895716A (en) * | 1987-06-09 | 1990-01-23 | Biogen, Inc. | Stabilized formulations of gamma interferons |
US4871538A (en) * | 1987-07-13 | 1989-10-03 | Schering Corporation | Insoluble copper-alpha interferon complex |
US5151265A (en) * | 1987-11-03 | 1992-09-29 | Genentech, Inc. | Gamma interferon formulation |
US5004605A (en) * | 1987-12-10 | 1991-04-02 | Cetus Corporation | Low pH pharmaceutical compositions of recombinant β-interferon |
ES2058351T3 (es) * | 1988-01-29 | 1994-11-01 | Sumitomo Pharma | Un procedimiento para producir una formulacion de liberacion sostenida que es adecuada para el uso humano y veterinario. |
US5078997A (en) * | 1988-07-13 | 1992-01-07 | Cetus Corporation | Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers |
US5165921A (en) * | 1989-01-23 | 1992-11-24 | National Geno Sciences, Inc. | Method for treating condyloma acuminatum with interferon |
IT1240314B (it) * | 1989-09-28 | 1993-12-07 | Immunobiology Research Institutes, Inc. | Formulazioni acquose stabilizzate di piccoli peptidi. |
US5863530A (en) * | 1991-10-11 | 1999-01-26 | Spruson & Ferguson | Treating ophthalmic fibrosis using interferon-α |
JPH07501320A (ja) * | 1991-10-11 | 1995-02-09 | ギリーズ,マーク・セドリック | インタ−フェロン・アルファによる眼線維症の治療 |
AU669132B2 (en) * | 1991-10-11 | 1996-05-30 | Mark Cedric Gillies | Treating ophthalmic fibrosis using interferon-alpha |
US5236707A (en) * | 1991-11-08 | 1993-08-17 | Dallas Biotherapeutics, Inc. | Stabilization of human interferon |
LT3987B (en) | 1992-02-17 | 1996-06-25 | Fermentas Biotech Inst | Stabilized interferon compositions |
US5358708A (en) * | 1993-01-29 | 1994-10-25 | Schering Corporation | Stabilization of protein formulations |
US6270757B1 (en) * | 1994-04-21 | 2001-08-07 | Genetics Institute, Inc. | Formulations for IL-11 |
US6399296B1 (en) * | 1994-07-20 | 2002-06-04 | The General Hospital Corporation | Interaction trap systems for detecting protein interactions |
US5766582A (en) * | 1994-10-11 | 1998-06-16 | Schering Corporation | Stable, aqueous alfa interferon solution formulations |
ATE216590T1 (de) * | 1995-02-06 | 2002-05-15 | Genetics Inst | Arzneimittelformulierungen für il-12 |
US5656730A (en) * | 1995-04-07 | 1997-08-12 | Enzon, Inc. | Stabilized monomeric protein compositions |
US6126933A (en) * | 1995-06-27 | 2000-10-03 | Genetics Institute | Methods of treating inflammatory bowel diseases by administering IL-11 |
US6540993B1 (en) | 1995-06-27 | 2003-04-01 | Wyeth | Method of treating inflammatory bowel disease using a topical formulation of IL-11 |
EE04266B1 (et) * | 1996-12-24 | 2004-04-15 | Biogen, Incorporated | Interferooni stabiilne vedelkompositsioon |
US20030190307A1 (en) | 1996-12-24 | 2003-10-09 | Biogen, Inc. | Stable liquid interferon formulations |
ATE224726T1 (de) † | 1997-09-23 | 2002-10-15 | Rentschler Biotech Gmbh | Flüssige interferon-beta-formulierungen |
WO1999018959A1 (en) * | 1997-10-14 | 1999-04-22 | Eisai Co., Ltd. | Pharmaceutical formulation comprising glycine as a stabilizer |
US7230014B1 (en) | 1997-10-14 | 2007-06-12 | Eisai Co., Ltd. | Pharmaceutical formulation comprising glycine as a stabilizer |
US7511120B2 (en) * | 1997-10-16 | 2009-03-31 | Synageva Biopharma Corp. | Glycosylated G-CSF obtained from a transgenic chicken |
US20090074718A1 (en) * | 1997-10-16 | 2009-03-19 | Ivarie Robert D | Avian derived erythropoietin |
US8563803B2 (en) * | 1997-10-16 | 2013-10-22 | Synageva Biopharma Corp. | Method of making protein in an egg of a transgenic chicken |
US20040019923A1 (en) * | 1997-10-16 | 2004-01-29 | Ivarie Robert D. | Exogenous proteins expressed in avians and their eggs |
US7129390B2 (en) * | 1997-10-16 | 2006-10-31 | Avigenics, Inc | Poultry Derived Glycosylated Interferon Alpha 2b |
US20030166525A1 (en) * | 1998-07-23 | 2003-09-04 | Hoffmann James Arthur | FSH Formulation |
US6281337B1 (en) | 1998-11-12 | 2001-08-28 | Schering Corporation | Methods for conversion of protein isoforms |
ES2348104T3 (es) | 1998-11-12 | 2010-11-30 | Schering Corporation | Metodo para la conversion de isoformas de interferon y productos de las mismas. |
CN1286969C (zh) * | 1999-12-14 | 2006-11-29 | 热生物之星公司 | 多肽和抗原的稳定稀释剂 |
WO2002036627A2 (en) | 2000-11-03 | 2002-05-10 | Pbl Biomedical Laboratories | Interferons, uses and compositions related thereto |
EP1356809A4 (de) * | 2000-12-28 | 2008-05-14 | Takeda Pharmaceutical | Retardzubereitungen |
AR034749A1 (es) * | 2001-07-09 | 2004-03-17 | Schering Ag | Formulaciones de interferon beta humano |
DK3025726T3 (da) | 2002-01-18 | 2019-12-09 | Biogen Ma Inc | Polyalkylenpolymerforbindelser og anvendelser deraf |
US20050232899A1 (en) * | 2002-05-31 | 2005-10-20 | Aradigm Corporation | Compositions methods and systems for pulmonary delivery of recombinant human interferon alpha-2b |
US6830744B2 (en) | 2002-05-31 | 2004-12-14 | Aradigm Corporation | Compositions methods and systems for pulmonary delivery of recombinant human interferon alpha-2b |
US7803362B2 (en) * | 2003-01-24 | 2010-09-28 | Synageva Biopharma Corp. | Glycosylated interferon alpha |
JP4699991B2 (ja) * | 2003-04-02 | 2011-06-15 | アレス トレーディング ソシエテ アノニム | 非イオン性界面活性剤を一緒に伴うfsh及びlhの液体医薬組成物 |
EP1638595B1 (de) * | 2003-06-20 | 2013-03-20 | Ares Trading S.A. | Gefriergetrocknete fsh / lh formulierungen |
WO2006020720A2 (en) * | 2004-08-12 | 2006-02-23 | Schering Corporation | Stable pegylated interferon formulation |
US20080064862A1 (en) | 2004-12-29 | 2008-03-13 | Avigenics, Inc. | Transgene expression in a avians |
JP2008531553A (ja) * | 2005-02-25 | 2008-08-14 | メディジーンズ カンパニー リミテッド | 血漿または血清を含むアベリノ角膜ジストロフィー治療用の医薬組成物 |
US8124732B2 (en) | 2005-06-24 | 2012-02-28 | Synageva Biopharma Corp. | Composition comprising isolated human CTLA4-Fc fusion protein produced in a transgenic chicken |
US20070003564A1 (en) * | 2005-06-30 | 2007-01-04 | Hurley John K | Diluent for immunohistochemistry |
WO2008048228A2 (en) * | 2005-08-12 | 2008-04-24 | Department Of The Army | Glycine stabilized lyophilized plasma |
CU23432B6 (es) | 2005-11-02 | 2009-10-16 | Ct Ingenieria Genetica Biotech | Formulaciones estabilizadas que contienen a los interferones gamma y alfa en proporciones potenciadoras |
US7812127B2 (en) | 2006-03-17 | 2010-10-12 | Synageva Biopharma Corp. | Glycosylated human G-CSF |
US20090105462A1 (en) * | 2006-11-09 | 2009-04-23 | Ivarie Robert D | Glycosylated erythropoietin |
ES2431054T3 (es) * | 2006-11-24 | 2013-11-22 | Cadila Healthcare Limited | Formulaciones de los conjugados de PEG-interferón alfa |
EP2170268A2 (de) | 2007-06-25 | 2010-04-07 | Amgen, Inc. | Zusammensetzungen von spezifischen bindungsmitteln für den hepatozyten-wachstumsfaktor |
WO2009079837A1 (fr) * | 2007-12-18 | 2009-07-02 | Hangzhou Jiuyuan Gene Engineering Co., Ltd. | Formulation pharmaceutique contenant une protéine de fusion sérum albumine humaine recombinante-interféron alpha |
NZ599783A (en) | 2009-11-03 | 2013-10-25 | Grifols Therapeutics Inc | Composition and use for alpha-1 proteinase inhibitor |
PT2503995T (pt) | 2009-11-24 | 2017-11-23 | Grifols Therapeutics Inc | Métodos de liofilização, composições e kits |
US20130008191A1 (en) * | 2011-07-07 | 2013-01-10 | Suchak Naresh J | Methods for freezing and thawing proteins |
WO2017030563A1 (en) | 2014-08-19 | 2017-02-23 | Biogen Ma Inc | Pegylation method |
CN106421755A (zh) * | 2016-11-03 | 2017-02-22 | 广州凯耀资产管理有限公司 | 一种干扰素组合物及其制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2553497A (en) * | 1946-02-04 | 1951-05-15 | L Inst De Serotherapie Hemopoi | Hemostatic composition of thrombin and glycocoll |
US2806815A (en) * | 1955-04-12 | 1957-09-17 | Ortho Pharma Corp | Stabilized hyaluronidase |
GB866423A (en) * | 1958-03-21 | 1961-04-26 | Armour & Co | Improvements in or relating to chymotrypsin solutions |
US3016398A (en) * | 1959-04-06 | 1962-01-09 | Staley Mfg Co A E | Stabilized phytic acid solutions and methods of preparation thereof |
GB900115A (en) * | 1960-06-15 | 1962-07-04 | Armour & Co | Improvements in or relating to trypsin solutions |
JPS5495795A (en) * | 1978-01-13 | 1979-07-28 | Toray Ind Inc | Production of interferon |
IN150740B (de) * | 1978-11-24 | 1982-12-04 | Hoffmann La Roche | |
JPS55102519A (en) * | 1979-01-31 | 1980-08-05 | Green Cross Corp:The | Stabilization of interferon |
US4198479A (en) * | 1979-03-30 | 1980-04-15 | Merck & Co., Inc. | Replacement of animal serum proteins by human albumin for growth and interferon production by Namalva cells |
US4252791A (en) * | 1979-10-19 | 1981-02-24 | The Medical College Of Wisconsin, Inc. | Interferon stabilization |
US4337242A (en) * | 1980-02-05 | 1982-06-29 | Merck & Co., Inc. | Vaccine stabilizer containing L-glutamic acid and L-arginine |
FR2505657A1 (fr) * | 1981-05-13 | 1982-11-19 | Pasteur Institut | Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation |
-
1982
- 1982-12-15 EP EP82111665A patent/EP0082481B2/de not_active Expired - Lifetime
- 1982-12-15 DE DE8282111665T patent/DE3262575D1/de not_active Expired
- 1982-12-20 FI FI824366A patent/FI70794C/fi not_active IP Right Cessation
- 1982-12-20 IL IL67517A patent/IL67517A/xx not_active IP Right Cessation
- 1982-12-20 PH PH28296A patent/PH19869A/en unknown
- 1982-12-20 AU AU91688/82A patent/AU558966B2/en not_active Expired
- 1982-12-20 NO NO82824285A patent/NO161036C/no not_active IP Right Cessation
- 1982-12-20 NZ NZ202856A patent/NZ202856A/en unknown
- 1982-12-21 OA OA57876A patent/OA07282A/xx unknown
- 1982-12-21 DK DK565882A patent/DK158873C/da not_active IP Right Cessation
- 1982-12-21 IE IE3046/82A patent/IE54468B1/en not_active IP Right Cessation
- 1982-12-21 CA CA000418237A patent/CA1207665A/en not_active Expired
- 1982-12-21 PT PT76013A patent/PT76013B/pt unknown
- 1982-12-22 HU HU824137A patent/HU190649B/hu unknown
-
1983
- 1983-09-16 US US06/532,886 patent/US4496537A/en not_active Expired - Lifetime
-
1987
- 1987-08-27 SG SG706/87A patent/SG70687G/en unknown
- 1987-12-10 HK HK944/87A patent/HK94487A/xx not_active IP Right Cessation
- 1987-12-30 MY MY705/87A patent/MY8700705A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DK565882A (da) | 1983-06-24 |
EP0082481B1 (de) | 1985-03-13 |
EP0082481B2 (de) | 1990-09-12 |
IE54468B1 (en) | 1989-10-25 |
US4496537A (en) | 1985-01-29 |
NO824285L (no) | 1983-06-24 |
HK94487A (en) | 1987-12-18 |
IL67517A0 (en) | 1983-05-15 |
FI824366A0 (fi) | 1982-12-20 |
FI824366L (fi) | 1983-06-24 |
AU9168882A (en) | 1983-06-30 |
IE823046L (en) | 1983-06-23 |
FI70794B (fi) | 1986-07-18 |
DK158873B (da) | 1990-07-30 |
FI70794C (fi) | 1986-10-27 |
EP0082481A1 (de) | 1983-06-29 |
DE3262575D1 (en) | 1985-04-18 |
NZ202856A (en) | 1985-12-13 |
CA1207665A (en) | 1986-07-15 |
SG70687G (en) | 1988-02-19 |
PH19869A (en) | 1986-08-13 |
IL67517A (en) | 1988-11-30 |
NO161036B (no) | 1989-03-20 |
NO161036C (no) | 1989-06-28 |
MY8700705A (en) | 1987-12-31 |
DK158771B (da) | 1990-07-16 |
DK158873C (da) | 1990-12-31 |
HU190649B (en) | 1986-09-29 |
PT76013B (en) | 1986-03-11 |
PT76013A (en) | 1983-01-01 |
AU558966B2 (en) | 1987-02-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
OA07282A (fr) | Composition pharmaceutique lyophilisée contenant de l'interféron procédé pour la préparation et procédé pour sa stabilisation. | |
OA07103A (fr) | Nouvelles 1,2-diaminocyclobutène-3,4-diones, leur procédé de préparation et composition pharmaceutique les contenant. | |
OA08647A (fr) | Dérivés d'imidazole, procédés pour leur préparation et composition pharmaceutique les contenant. | |
BE890574A (fr) | Derive d'aminoalcoyl-furanne, procede pour sa preparation et composition pharmaceutique le contenant | |
FR2531087B1 (fr) | Nouvelle forme d'ester de cefuroxime, procede pour sa preparation et composition pharmaceutique la contenant | |
PT84964A (en) | Process for the preparation of 1,5-diaryl-3-substituted-pyrazoles and of pharmaceutical compositions containing them | |
FR2569402B1 (fr) | Derives d'acide 3,5-pyridine-dicarboxylique, procede pour leur preparation et composition pharmaceutique les contenant | |
PT87492A (pt) | Process for the preparation of benzo ]b" pyrrans and pyranopyridines and pharmaceutical compositions containing them | |
FR2567131B1 (fr) | Nouveaux derives de ganglioside, procede pour leur obtention et composition pharmaceutique les contenant | |
FR2518095B1 (fr) | Nouveaux l-oxa-, thia- et aza-spirocyclo-benzene-acetamides et benzamides, leur procede de preparation et composition pharmaceutique les contenant | |
IL67172A (en) | Derivatives of cis,endo-2-azabicyclo-(3.3.0)-octane-3-carboxylic acid,process for their preparation and pharmaceutical agents containing these compounds | |
MC1915A1 (fr) | Procédés pour la préparation de 2',3'-didésoxynucléosides et de formulations pharmaceutiques en contenant | |
OA09441A (fr) | "Procédés de préparation de ptéridin-4(3H)-ones, et de compositions médicamenteuses les contenant". | |
FR2569702B1 (fr) | Nouvelle 4'-deschlororebeccamycine, composition pharmaceutique la contenant et procede pour sa preparation | |
BE892552A (fr) | Nouveaux amido-aminoacides, compositions pharmaceutiques les contenant et procede de preparation de ces amido-aminoacides | |
OA07341A (fr) | Nouveaux oximéthers, procédé pour leur préparation, agents contenant les nouveaux oximéthers et leur application. | |
PT75042A (en) | Process for the preparation of apovincaminates and pharmaceutical compositions containing them | |
FR2600061B1 (fr) | Derives d'indole, composition pharmaceutique les contenant et procede pour leur preparation | |
PT84184A (pt) | Process for the preparation of 8 alpha-acylaminoergolines and of pharmaceutical compositions containing them | |
PT76870A (en) | Process for the preparation of 1,4-dihydropiridine derivatives and pharmaceutical compositions containing them | |
FR2519021B1 (fr) | Procede de stabilisation de la serrapeptase, composition contenant cette serrapeptase stabilisee et preparation de cette composition | |
FR2563519B1 (fr) | Derives d'iminothiazolidine, procede pour leur preparation et compositions pharmaceutiques les contenant | |
PT75265B (en) | Process for the preparation of diazabicyclicononanes substituted and pharmaceutical composition containing them | |
FR2528422B1 (fr) | Nouveaux derives du 1,2,3,4-tetrahydronaphtalene, procede pour leur preparation et composition pharmaceutique contenant ces derives | |
HU901579D0 (en) | Process for the preparation of substituted /quinolin-2-yl-methoxy/-phenyl-n'n-sulfonyl-ureas and pharmaceutical compositions containing such compounds |