ES2058351T3 - Un procedimiento para producir una formulacion de liberacion sostenida que es adecuada para el uso humano y veterinario. - Google Patents
Un procedimiento para producir una formulacion de liberacion sostenida que es adecuada para el uso humano y veterinario.Info
- Publication number
- ES2058351T3 ES2058351T3 ES89101428T ES89101428T ES2058351T3 ES 2058351 T3 ES2058351 T3 ES 2058351T3 ES 89101428 T ES89101428 T ES 89101428T ES 89101428 T ES89101428 T ES 89101428T ES 2058351 T3 ES2058351 T3 ES 2058351T3
- Authority
- ES
- Spain
- Prior art keywords
- producing
- human
- procedure
- release formulation
- sustained release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2063—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Abstract
FORMULACION DE LIBERACION CONTROLADA QUE CONTIENE UN COMPUESTO ORGANICO ACIDO O UN ANHIDRIDO DE ACIDO O UN ESTER CAPAZ DE GENERAR UNO DE LOS COMPUESTOS ORGANICOSA ACIDOS POR HIDROLISIS, JUNTO CON UN INGREDIENTE ACTIVO Y COLAGENO COMO VEHICULO, SIENDO DICHA FORMULACION CAPAZ DE EXHIBIR UN PERFIL DE LIBERACION PREDETERMINADO DEL INGREDIENTE ACTIVO. SE INCLUYE UN PROCESO PARA PRODUCIR DICHA FORMULACION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2045988 | 1988-01-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2058351T3 true ES2058351T3 (es) | 1994-11-01 |
Family
ID=12027662
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES89101428T Expired - Lifetime ES2058351T3 (es) | 1988-01-29 | 1989-01-27 | Un procedimiento para producir una formulacion de liberacion sostenida que es adecuada para el uso humano y veterinario. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5236704A (es) |
EP (1) | EP0326151B1 (es) |
AT (1) | ATE90570T1 (es) |
CA (1) | CA1338839C (es) |
DE (1) | DE68907066T2 (es) |
ES (1) | ES2058351T3 (es) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5422340A (en) * | 1989-09-01 | 1995-06-06 | Ammann; Arthur J. | TGF-βformulation for inducing bone growth |
IE912365A1 (en) * | 1990-07-23 | 1992-01-29 | Zeneca Ltd | Continuous release pharmaceutical compositions |
JP3179538B2 (ja) * | 1990-12-11 | 2001-06-25 | ノバルティス アクチエンゲゼルシャフト | 安定なヒトカルシトニンの水性溶液 |
GR1002610B (el) * | 1991-01-02 | 1997-02-20 | Johnson & Johnson Consumer Products Inc. | Θεραπευτικες συνθεσεις πληγων που περιεχουν παραγοντα αναπτυξης ινοβλαστων και ασκορβικον οξυ. |
KR100225153B1 (ko) * | 1991-04-08 | 1999-10-15 | 다께우찌 마사야쓰 | 단백성 생리학적 활성 물질을 함유하는 다공성 고형 제제 |
US5571788A (en) * | 1991-12-09 | 1996-11-05 | Ciba-Geigy Corporation | Stable calcitonin pharmaceutical compositions |
WO1995002411A1 (en) * | 1993-07-16 | 1995-01-26 | Mallinckrodt Veterinary Limited | Stabilised polypeptide growth factor formulation at low ph |
US6270757B1 (en) * | 1994-04-21 | 2001-08-07 | Genetics Institute, Inc. | Formulations for IL-11 |
DE4414755C2 (de) * | 1994-04-27 | 2000-11-16 | Lohmann Therapie Syst Lts | Kollagenzubereitung zur gesteuerten Abgabe von Wirkstoffen, Verfahren und Verwendung |
DE69527141T2 (de) | 1994-04-29 | 2002-11-07 | Scimed Life Systems Inc | Stent mit kollagen |
US6126933A (en) * | 1995-06-27 | 2000-10-03 | Genetics Institute | Methods of treating inflammatory bowel diseases by administering IL-11 |
US6540993B1 (en) | 1995-06-27 | 2003-04-01 | Wyeth | Method of treating inflammatory bowel disease using a topical formulation of IL-11 |
US6998268B2 (en) * | 1995-07-03 | 2006-02-14 | Dainippon Sumitomo Pharma Co. Ltd. | Gene preparations |
HUP9602024A3 (en) * | 1996-07-25 | 1999-05-28 | Toth Sandor | Pharmaceutical composition containing aminoacid for external use |
CA2217134A1 (en) * | 1996-10-09 | 1998-04-09 | Sumitomo Pharmaceuticals Co., Ltd. | Sustained release formulation |
TW586934B (en) * | 1997-05-19 | 2004-05-11 | Sumitomo Pharma | Immunopotentiating composition |
DE19739031A1 (de) * | 1997-09-05 | 1999-03-11 | Suwelack Nachf Dr Otto | Mittel zur peroralen Verabreichung, seine Herstellung und Verwendung |
EP1069912B1 (en) * | 1998-04-03 | 2007-07-25 | Novartis Vaccines and Diagnostics, Inc. | Injectable igf-formulations containing succinate as buffering agent |
AU755126B2 (en) * | 1998-05-22 | 2002-12-05 | Dainippon Sumitomo Pharma Co., Ltd. | Stable gene preparations |
WO2001068124A2 (en) | 2000-03-15 | 2001-09-20 | The Brigham And Women's Hospital, Inc. | Suppression of vascular disorders by mucosal administration of heat shock protein peptides |
US20020114795A1 (en) | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
US20030211095A1 (en) * | 2002-05-08 | 2003-11-13 | Abd. Al-Roof Higazi | Peptide for regulation of urokinase plasminogen activator and method of optimizing therapeutic efficacy |
WO2003066083A1 (fr) * | 2002-02-04 | 2003-08-14 | Sumitomo Pharmaceuticals Company, Limited | Preparations pour le traitement de fracture osseuse de deperdition osseuse ou d'augmentation la densite osseuse |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
PL1684782T3 (pl) | 2003-10-03 | 2016-03-31 | Thorn Bioscience Llc | Sposób synchronizacji owulacji dla zsynchronizowanego rozmnażania bez wykrywania rui |
EP1682537B1 (en) | 2003-11-05 | 2012-03-28 | SARcode Bioscience Inc. | Modulators of cellular adhesion |
EP1874334A4 (en) * | 2005-04-15 | 2011-03-30 | Vascular Biogenics Ltd | COMPOSITIONS WITH BETA 2-GLYCOPROTEIN I-PEPTIDES FOR THE PREVENTION AND / OR TREATMENT OF VASCULAR DISEASES |
PL2444079T3 (pl) | 2005-05-17 | 2017-07-31 | Sarcode Bioscience Inc. | Kompozycje i sposoby leczenia chorób oczu |
US7718616B2 (en) | 2006-12-21 | 2010-05-18 | Zimmer Orthobiologics, Inc. | Bone growth particles and osteoinductive composition thereof |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
CA2688161C (en) | 2007-06-04 | 2020-10-20 | Kunwar Shailubhai | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US20090155176A1 (en) | 2007-10-19 | 2009-06-18 | Sarcode Corporation | Compositions and methods for treatment of diabetic retinopathy |
US20090258069A1 (en) * | 2008-04-15 | 2009-10-15 | John Burnier | Delivery of LFA-1 antagonists to the gastrointestinal system |
WO2009139817A2 (en) | 2008-04-15 | 2009-11-19 | Sarcode Corporation | Crystalline pharmaceutical and methods of preparation and use thereof |
ES2522968T3 (es) | 2008-06-04 | 2014-11-19 | Synergy Pharmaceuticals Inc. | Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
BRPI1014362A2 (pt) | 2009-04-23 | 2016-04-05 | Pennatek Llc | método e composição para sincronizar o tempo de inseminação |
WO2011050175A1 (en) | 2009-10-21 | 2011-04-28 | Sarcode Corporation | Crystalline pharmaceutical and methods of preparation and use thereof |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
JP2013542837A (ja) | 2010-11-15 | 2013-11-28 | ジンマー オーソバイオロジクス,インコーポレイティド | 骨空隙充填剤 |
EP3715345B1 (en) | 2012-07-25 | 2024-04-10 | Novartis AG | Preparation of lfa-1 inhibitor |
CA2892762C (en) | 2012-11-28 | 2022-07-19 | Jbs United Animal Health Ii Llc | Method for synchronizing time of insemination in gilts |
WO2014131024A2 (en) | 2013-02-25 | 2014-08-28 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
EP3054969B1 (en) | 2013-10-10 | 2021-03-10 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions |
CN108884130B (zh) | 2016-01-11 | 2022-09-13 | 博士医疗爱尔兰有限公司 | 用于治疗溃疡性结肠炎的制剂和方法 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4294241A (en) * | 1977-06-09 | 1981-10-13 | Teruo Miyata | Collagen skin dressing |
US4164559A (en) * | 1977-09-21 | 1979-08-14 | Cornell Research Foundation, Inc. | Collagen drug delivery device |
DE2843963A1 (de) * | 1978-10-09 | 1980-04-24 | Merck Patent Gmbh | Im koerper resorbierbare geformte masse auf basis von kollagen und ihre verwendung in der medizin |
JPS56122317A (en) * | 1980-02-29 | 1981-09-25 | Koken:Kk | Drug transporting material and its preparation |
DE3171774D1 (en) * | 1980-03-31 | 1985-09-19 | Teijin Ltd | Pharmaceutical composition for intrarectal administration, and suppository prepared therefrom |
CA1184492A (en) * | 1981-01-14 | 1985-03-26 | Masataka Morishita | Preparation having excellent absorption property |
EP0082481B2 (en) * | 1981-12-23 | 1990-09-12 | Schering Corporation | Stabilised alpha-interferon formulations and their preparation |
US4409332A (en) * | 1982-01-12 | 1983-10-11 | Jefferies Steven R | Collagen-enzyme conjugates that exhibit no inflammatory response and method for making the same |
JPS597684A (ja) * | 1982-07-05 | 1984-01-14 | 株式会社日立製作所 | エスカレ−タ− |
JPS5919925A (ja) * | 1982-07-27 | 1984-02-01 | Stanley Electric Co Ltd | 2層式液晶セルの製造方法 |
EP0138216B1 (en) * | 1983-10-14 | 1993-01-07 | Sumitomo Pharmaceuticals Company, Limited | Sustained-release ifn preparation for parenteral administration |
DE3484951D1 (de) * | 1983-10-14 | 1991-09-26 | Sumitomo Pharma | Verlaengerte praeparate mit verzoegerter abgabe. |
DE3484584D1 (de) * | 1983-10-14 | 1991-06-20 | Sumitomo Pharma | Injektionen mit verzoegerter abgabe. |
US4774091A (en) * | 1983-10-14 | 1988-09-27 | Sumitomo Pharmaceuticals Company, Ltd. | Long-term sustained-release preparation |
JPS60100516A (ja) * | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
DE3409372A1 (de) * | 1984-03-14 | 1985-09-19 | Dr. Ruhland Nachf. GmbH, 8425 Neustadt | Material zum vitalisieren von implantatoberflaechen |
DE3688188T2 (de) * | 1985-12-27 | 1993-10-14 | Sumitomo Pharma | Verfahren zur Herstellung einer Formulierung mit verzögerter Freisetzung. |
US4816568A (en) * | 1986-05-16 | 1989-03-28 | International Minerals & Chemical Corp. | Stabilization of growth hormones |
US5057317A (en) * | 1987-03-24 | 1991-10-15 | Chugai Seiyaku Kabushiki Kaisha | Slow-release pharmaceutical agent |
JPH0720483B2 (ja) * | 1987-05-29 | 1995-03-08 | 住友製薬株式会社 | 高粘度糊状組成物成形体の乾燥法 |
-
1989
- 1989-01-27 US US07/302,476 patent/US5236704A/en not_active Expired - Lifetime
- 1989-01-27 ES ES89101428T patent/ES2058351T3/es not_active Expired - Lifetime
- 1989-01-27 CA CA000589427A patent/CA1338839C/en not_active Expired - Fee Related
- 1989-01-27 DE DE89101428T patent/DE68907066T2/de not_active Expired - Fee Related
- 1989-01-27 AT AT89101428T patent/ATE90570T1/de not_active IP Right Cessation
- 1989-01-27 EP EP89101428A patent/EP0326151B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE90570T1 (de) | 1993-07-15 |
EP0326151A3 (en) | 1991-03-13 |
DE68907066T2 (de) | 1993-12-16 |
CA1338839C (en) | 1997-01-14 |
US5236704A (en) | 1993-08-17 |
EP0326151A2 (en) | 1989-08-02 |
EP0326151B1 (en) | 1993-06-16 |
DE68907066D1 (de) | 1993-07-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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