NO991831L - Substituerte tricykliske forbindelser - Google Patents

Substituerte tricykliske forbindelser

Info

Publication number
NO991831L
NO991831L NO991831A NO991831A NO991831L NO 991831 L NO991831 L NO 991831L NO 991831 A NO991831 A NO 991831A NO 991831 A NO991831 A NO 991831A NO 991831 L NO991831 L NO 991831L
Authority
NO
Norway
Prior art keywords
tricyclic compounds
substituted tricyclic
substituted
compounds
tricyclic
Prior art date
Application number
NO991831A
Other languages
English (en)
Other versions
NO991831D0 (no
NO314899B1 (no
Inventor
Nicholas James Bach
Robert Delane Dillard
Susan Elizabeth Draheim
Jr John Michael Morin
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO991831D0 publication Critical patent/NO991831D0/no
Publication of NO991831L publication Critical patent/NO991831L/no
Publication of NO314899B1 publication Critical patent/NO314899B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572Five-membered rings
    • C07F9/5728Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fats And Perfumes (AREA)
  • Pyridine Compounds (AREA)
NO19991831A 1996-10-30 1999-04-16 Substituerte tricykliske forbindelser samt preparater inneholdende forbindelsene NO314899B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2984996P 1996-10-30 1996-10-30
PCT/US1997/019183 WO1998018464A1 (en) 1996-10-30 1997-10-23 Substituted tricyclics

Publications (3)

Publication Number Publication Date
NO991831D0 NO991831D0 (no) 1999-04-16
NO991831L true NO991831L (no) 1999-06-21
NO314899B1 NO314899B1 (no) 2003-06-10

Family

ID=21851210

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19991831A NO314899B1 (no) 1996-10-30 1999-04-16 Substituerte tricykliske forbindelser samt preparater inneholdende forbindelsene

Country Status (26)

Country Link
EP (1) EP0839806B1 (no)
JP (1) JP2001503055A (no)
KR (1) KR20000049210A (no)
CN (1) CN1233176A (no)
AR (1) AR010050A1 (no)
AT (1) ATE244703T1 (no)
AU (1) AU734096B2 (no)
BR (1) BR9713261A (no)
CA (1) CA2269203A1 (no)
CO (1) CO4920250A1 (no)
CZ (1) CZ136899A3 (no)
DE (1) DE69723393T2 (no)
DK (1) DK0839806T3 (no)
EA (1) EA003992B1 (no)
ES (1) ES2202560T3 (no)
ID (1) ID18685A (no)
IL (1) IL129481A0 (no)
NO (1) NO314899B1 (no)
NZ (1) NZ335246A (no)
PE (1) PE10999A1 (no)
PL (1) PL332896A1 (no)
PT (1) PT839806E (no)
TR (1) TR199900956T2 (no)
TW (1) TW513428B (no)
WO (1) WO1998018464A1 (no)
YU (1) YU19299A (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1011670A4 (en) * 1997-08-28 2004-10-27 Lilly Co Eli PROCESS FOR TREATING NON-RHUMATOID POLYARTHRITIS
CN1303384A (zh) 1998-03-31 2001-07-11 盐野义制药株式会社 吡咯并[1,2-a]吡嗪sPLA2抑制剂
ID23219A (id) * 1998-04-17 2000-03-30 Lilly Co Eli Trisiklik tersubstitusi
DZ2769A1 (fr) * 1998-04-17 2003-12-01 Lilly Co Eli Composés tricycliques substitués.
BR9910095A (pt) 1998-05-01 2000-12-26 Lilly Co Eli Compostos inibidores de spla2 para tratamento de doença
CN1302300A (zh) 1998-05-21 2001-07-04 盐野义制药株式会社 吡咯并[1,2-b]哒嗪sPLA2抑制剂
DE69931963D1 (de) * 1998-10-14 2006-07-27 Shionogi & Co Spla2-inhibitoren zur behandlung von ischämischen reperfusionsschäden
US6448284B1 (en) * 1998-12-22 2002-09-10 Eli Lilly And Company Substituted tricyclics
WO2001005789A1 (fr) 1999-07-19 2001-01-25 Shionogi & Co., Ltd. Composes tricycliques a action inhibitrice a l'encontre de spla¿2?
AU6023200A (en) 1999-08-02 2001-02-19 Shionogi & Co., Ltd. Tricyclic compounds having spla2-inhibitory activities
WO2001014378A1 (fr) 1999-08-23 2001-03-01 Shionogi & Co., Ltd. DERIVES DE PYRROLOTRIAZINE A ACTIVITES INHIBANT sPLA¿2?
MY125942A (en) 1999-09-07 2006-09-29 Upjohn Co Aminoalkoxy carbazoles for the treatment of cns diseases
US6756376B1 (en) 1999-11-15 2004-06-29 Shionogi & Co., Ltd. Tricyclic azaindolizine derivatives having an sPLA2-inhibitory activities
AU2728301A (en) * 2000-01-06 2001-07-16 Eli Lilly And Company Combination therapy for the treatment of inflammatory and respiratory diseases
WO2002000256A1 (en) 2000-06-29 2002-01-03 Shionogi & Co., Ltd. Remedies for cirrhosis
WO2002000621A1 (fr) 2000-06-29 2002-01-03 Shionogi & Co., Ltd. Composes inhibiteurs de la spla2 de type x
US6872743B2 (en) 2000-12-18 2005-03-29 Eli Lilly And Company sPLA2 inhibitors
TWI314457B (no) 2001-03-19 2009-09-11 Shionogi & Co
AUPS282602A0 (en) 2002-06-07 2002-06-27 Garvan Institute Of Medical Research Method of inhibiting cell proliferation
DK1852433T3 (da) 2004-10-29 2012-01-30 Zeria Pharm Co Ltd Carbazolderivat, solvate deraf eller farmaceutisk acceptabelt salt deraf
US10632102B2 (en) 2015-06-15 2020-04-28 Raziel Therapeutics Ltd Carbazole derivatives for the treatment of fibrotic diseases and related symptoms, and conditions thereof
CN112409493B (zh) * 2020-08-12 2022-09-30 浙江工业大学 一种重组融合酶及其在乙醛酸甲酯合成中的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3479391A (en) * 1966-10-03 1969-11-18 Squibb & Sons Inc Delta**3,14-17alpha-hydroxy-norprogesterone and esters
US3939177A (en) * 1972-11-22 1976-02-17 Sterling Drug Inc. 4-Aminomethyl-9-benzyl-1,2,3,4-tetrahydrocarbazoles
US3979391A (en) * 1972-11-22 1976-09-07 Sterling Drug Inc. 1,2,3,4-Tetrahydrocarbazoles
US5420289A (en) * 1989-10-27 1995-05-30 American Home Products Corporation Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
IL109311A0 (en) * 1993-04-16 1994-07-31 Lilly Co Eli 1H-indole-3-acetamide sPla2 inhibitors

Also Published As

Publication number Publication date
NO991831D0 (no) 1999-04-16
CA2269203A1 (en) 1998-05-07
EA003992B1 (ru) 2003-12-25
TW513428B (en) 2002-12-11
AR010050A1 (es) 2000-05-17
PE10999A1 (es) 1999-02-10
NZ335246A (en) 2001-09-28
ID18685A (id) 1998-04-30
TR199900956T2 (xx) 1999-07-21
AU5149498A (en) 1998-05-22
BR9713261A (pt) 2000-03-28
IL129481A0 (en) 2000-02-29
ATE244703T1 (de) 2003-07-15
CO4920250A1 (es) 2000-05-29
CN1233176A (zh) 1999-10-27
YU19299A (sh) 2000-03-21
AU734096B2 (en) 2001-06-07
EP0839806A1 (en) 1998-05-06
CZ136899A3 (cs) 1999-09-15
EP0839806B1 (en) 2003-07-09
PT839806E (pt) 2003-11-28
PL332896A1 (en) 1999-10-25
KR20000049210A (ko) 2000-07-25
NO314899B1 (no) 2003-06-10
EA199900305A1 (ru) 1999-12-29
JP2001503055A (ja) 2001-03-06
WO1998018464A1 (en) 1998-05-07
ES2202560T3 (es) 2004-04-01
DE69723393T2 (de) 2004-06-09
DE69723393D1 (de) 2003-08-14
DK0839806T3 (da) 2003-10-27

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