NO982989L - Use of inhibitors of the cellular Na + / H + exchanger (NHE) for the manufacture of a medicament for respiratory stimulation - Google Patents
Use of inhibitors of the cellular Na + / H + exchanger (NHE) for the manufacture of a medicament for respiratory stimulationInfo
- Publication number
- NO982989L NO982989L NO982989A NO982989A NO982989L NO 982989 L NO982989 L NO 982989L NO 982989 A NO982989 A NO 982989A NO 982989 A NO982989 A NO 982989A NO 982989 L NO982989 L NO 982989L
- Authority
- NO
- Norway
- Prior art keywords
- medicament
- nhe
- inhibitors
- exchanger
- cellular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60L—PROPULSION OF ELECTRICALLY-PROPELLED VEHICLES; SUPPLYING ELECTRIC POWER FOR AUXILIARY EQUIPMENT OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRODYNAMIC BRAKE SYSTEMS FOR VEHICLES IN GENERAL; MAGNETIC SUSPENSION OR LEVITATION FOR VEHICLES; MONITORING OPERATING VARIABLES OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRIC SAFETY DEVICES FOR ELECTRICALLY-PROPELLED VEHICLES
- B60L50/00—Electric propulsion with power supplied within the vehicle
- B60L50/50—Electric propulsion with power supplied within the vehicle using propulsion power supplied by batteries or fuel cells
- B60L50/60—Electric propulsion with power supplied within the vehicle using propulsion power supplied by batteries or fuel cells using power supplied by batteries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60L—PROPULSION OF ELECTRICALLY-PROPELLED VEHICLES; SUPPLYING ELECTRIC POWER FOR AUXILIARY EQUIPMENT OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRODYNAMIC BRAKE SYSTEMS FOR VEHICLES IN GENERAL; MAGNETIC SUSPENSION OR LEVITATION FOR VEHICLES; MONITORING OPERATING VARIABLES OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRIC SAFETY DEVICES FOR ELECTRICALLY-PROPELLED VEHICLES
- B60L7/00—Electrodynamic brake systems for vehicles in general
- B60L7/10—Dynamic electric regenerative braking
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60L—PROPULSION OF ELECTRICALLY-PROPELLED VEHICLES; SUPPLYING ELECTRIC POWER FOR AUXILIARY EQUIPMENT OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRODYNAMIC BRAKE SYSTEMS FOR VEHICLES IN GENERAL; MAGNETIC SUSPENSION OR LEVITATION FOR VEHICLES; MONITORING OPERATING VARIABLES OF ELECTRICALLY-PROPELLED VEHICLES; ELECTRIC SAFETY DEVICES FOR ELECTRICALLY-PROPELLED VEHICLES
- B60L7/00—Electrodynamic brake systems for vehicles in general
- B60L7/10—Dynamic electric regenerative braking
- B60L7/16—Dynamic electric regenerative braking for vehicles comprising converters between the power source and the motor
-
- E—FIXED CONSTRUCTIONS
- E01—CONSTRUCTION OF ROADS, RAILWAYS, OR BRIDGES
- E01C—CONSTRUCTION OF, OR SURFACES FOR, ROADS, SPORTS GROUNDS, OR THE LIKE; MACHINES OR AUXILIARY TOOLS FOR CONSTRUCTION OR REPAIR
- E01C19/00—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving
- E01C19/22—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving for consolidating or finishing laid-down unset materials
- E01C19/23—Rollers therefor; Such rollers usable also for compacting soil
- E01C19/26—Rollers therefor; Such rollers usable also for compacting soil self-propelled or fitted to road vehicles
-
- E—FIXED CONSTRUCTIONS
- E01—CONSTRUCTION OF ROADS, RAILWAYS, OR BRIDGES
- E01C—CONSTRUCTION OF, OR SURFACES FOR, ROADS, SPORTS GROUNDS, OR THE LIKE; MACHINES OR AUXILIARY TOOLS FOR CONSTRUCTION OR REPAIR
- E01C19/00—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving
- E01C19/22—Machines, tools or auxiliary devices for preparing or distributing paving materials, for working the placed materials, or for forming, consolidating, or finishing the paving for consolidating or finishing laid-down unset materials
- E01C19/23—Rollers therefor; Such rollers usable also for compacting soil
- E01C19/28—Vibrated rollers or rollers subjected to impacts, e.g. hammering blows
Abstract
De aktive ingrediensene identifisert som NHE-inhibitorer spesielt passende for fremstilling av et medikament for respiratorisk stimulering. De er spesielt godt egnet for behandling av søvnapnie og andre respiratoriske forstyrrelser.The active ingredients identified as NHE inhibitors are particularly suitable for the preparation of a medicament for respiratory stimulation. They are particularly suitable for the treatment of sleep apnea and other respiratory disorders.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19548812A DE19548812A1 (en) | 1995-12-27 | 1995-12-27 | Use of inhibitors of the cellular Na · + · / H · + · exchanger (NHE) for the manufacture of a medicament for respiratory stimulation |
PCT/EP1996/005614 WO1997024113A1 (en) | 1995-12-27 | 1996-12-13 | USE OF INHIBITORS OF THE CELLULAR Na+/H+ EXCHANGER (NHE) FOR THE PREPARATION OF A DRUG FOR RESPIRATORY STIMULATION |
Publications (2)
Publication Number | Publication Date |
---|---|
NO982989D0 NO982989D0 (en) | 1998-06-26 |
NO982989L true NO982989L (en) | 1998-08-06 |
Family
ID=7781474
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO982989A NO982989L (en) | 1995-12-27 | 1998-06-26 | Use of inhibitors of the cellular Na + / H + exchanger (NHE) for the manufacture of a medicament for respiratory stimulation |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0869779A1 (en) |
KR (1) | KR19990076802A (en) |
CN (1) | CN1207676A (en) |
AU (1) | AU717247B2 (en) |
BR (1) | BR9612287A (en) |
CA (1) | CA2241531A1 (en) |
CZ (1) | CZ202198DA3 (en) |
DE (1) | DE19548812A1 (en) |
HU (1) | HUP9900807A3 (en) |
IL (1) | IL125114A0 (en) |
MX (1) | MX9805141A (en) |
NO (1) | NO982989L (en) |
PL (1) | PL327693A1 (en) |
SK (1) | SK88398A3 (en) |
TR (1) | TR199801235T2 (en) |
WO (1) | WO1997024113A1 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9504537D0 (en) * | 1995-12-19 | 1995-12-19 | Jan Hedner | Ways of treating and diagnosing respiratory disorders during sleep and means of performing the method |
DE19945302A1 (en) * | 1999-09-22 | 2001-03-29 | Merck Patent Gmbh | Biphenyl derivatives as NHE-3 inhibitors |
DE10060292A1 (en) | 2000-12-05 | 2002-06-20 | Aventis Pharma Gmbh | Use of substituted benzimidazoles for the manufacture of a medicament for the treatment of diseases which can be influenced by inhibition of the Na + / H + exchanger and medicament containing them |
DE10163239A1 (en) * | 2001-12-21 | 2003-07-10 | Aventis Pharma Gmbh | Substituted imidazolidines, process for their preparation, their use as medicaments or diagnostic agents, and medicaments containing them |
KR101766619B1 (en) | 2008-12-31 | 2017-08-08 | 알데릭스, 인코포레이티드 | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
US10376481B2 (en) | 2012-08-21 | 2019-08-13 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
KR102138390B1 (en) | 2012-08-21 | 2020-07-27 | 알데릭스, 인코포레이티드 | Compounds and methods for inhibiting nhe-mediaded antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
EP2983667B1 (en) | 2013-04-12 | 2019-03-20 | Ardelyx, Inc. | Nhe3-binding compounds and methods for inhibiting phosphate transport |
CN106536502B (en) | 2014-07-25 | 2019-03-05 | 大正制药株式会社 | The phenyl tetrahydro isoquinoline compound being substituted by heteroaryl |
WO2018129552A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds useful for treating gastrointestinal tract disorders |
AU2018206479B2 (en) | 2017-01-09 | 2022-07-14 | Ardelyx, Inc. | Inhibitors of NHE-mediated antiport |
WO2019060051A1 (en) | 2017-08-04 | 2019-03-28 | Ardelyx, Inc. | Glycyrrhetinic acid derivatives for treating hyperkalemia |
WO2020163642A1 (en) | 2019-02-07 | 2020-08-13 | Ardelyx, Inc. | Glycyrrhetinic acid derivatives for use in treating hyperkalemia |
WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4325822A1 (en) * | 1993-07-31 | 1995-02-02 | Hoechst Ag | Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, and medicament containing them |
EP0639573A1 (en) * | 1993-08-03 | 1995-02-22 | Hoechst Aktiengesellschaft | Benzocondensed five membered heterocycles, process of their preparation, their use as drug, as diagnostic means and pharmaceuticals containing it |
DE4337609A1 (en) * | 1993-11-04 | 1995-05-11 | Boehringer Ingelheim Kg | Novel pyrazinecarboxamide derivatives, their preparation and their use in medicines |
DE4415873A1 (en) * | 1994-05-05 | 1995-11-09 | Hoechst Ag | Substituted bicyclic heteroaroylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicament containing them |
-
1995
- 1995-12-27 DE DE19548812A patent/DE19548812A1/en not_active Withdrawn
-
1996
- 1996-12-13 BR BR9612287-0A patent/BR9612287A/en unknown
- 1996-12-13 WO PCT/EP1996/005614 patent/WO1997024113A1/en not_active Application Discontinuation
- 1996-12-13 TR TR1998/01235T patent/TR199801235T2/en unknown
- 1996-12-13 EP EP96943956A patent/EP0869779A1/en not_active Withdrawn
- 1996-12-13 AU AU13720/97A patent/AU717247B2/en not_active Ceased
- 1996-12-13 CN CN96199403A patent/CN1207676A/en active Pending
- 1996-12-13 IL IL12511496A patent/IL125114A0/en unknown
- 1996-12-13 CA CA002241531A patent/CA2241531A1/en not_active Abandoned
- 1996-12-13 SK SK883-98A patent/SK88398A3/en unknown
- 1996-12-13 PL PL96327693A patent/PL327693A1/en unknown
- 1996-12-13 KR KR1019980704927A patent/KR19990076802A/en not_active Application Discontinuation
- 1996-12-13 HU HU9900807A patent/HUP9900807A3/en unknown
-
1998
- 1998-06-24 MX MX9805141A patent/MX9805141A/en unknown
- 1998-06-26 NO NO982989A patent/NO982989L/en not_active Application Discontinuation
-
2021
- 2021-03-03 CZ CZ982021A patent/CZ202198DA3/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE19548812A1 (en) | 1997-07-03 |
CZ202198DA3 (en) | 1998-11-11 |
PL327693A1 (en) | 1998-12-21 |
CA2241531A1 (en) | 1997-07-10 |
AU1372097A (en) | 1997-07-28 |
SK88398A3 (en) | 1999-03-12 |
TR199801235T2 (en) | 1998-10-21 |
IL125114A0 (en) | 1999-01-26 |
EP0869779A1 (en) | 1998-10-14 |
HUP9900807A2 (en) | 1999-07-28 |
BR9612287A (en) | 2005-05-24 |
KR19990076802A (en) | 1999-10-15 |
AU717247B2 (en) | 2000-03-23 |
MX9805141A (en) | 1998-10-31 |
HUP9900807A3 (en) | 2000-11-28 |
CN1207676A (en) | 1999-02-10 |
WO1997024113A1 (en) | 1997-07-10 |
NO982989D0 (en) | 1998-06-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |