NO963350L - 3'-substituert nukleosid-derivat - Google Patents

3'-substituert nukleosid-derivat

Info

Publication number: NO963350L
Authority: NO; Norway
Prior art keywords: group; nucleoside derivative; substituted nucleoside; substituted; chem
Prior art date: 1994-12-13

Application number

NO963350A

Other languages

English (en)

Other versions

NO305702B1 (no

NO963350D0 (no

Inventor

Akira Matsuda

Takuma Sasaki

Original Assignee

Akira Matsuda

Takuma Sasaki

Taiho Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-13

Filing date

1996-08-12

Publication date

1996-10-11

1996-08-12 Application filed by Akira Matsuda, Takuma Sasaki, Taiho Pharmaceutical Co Ltd filed Critical Akira Matsuda

1996-08-12 Publication of NO963350D0 publication Critical patent/NO963350D0/no

1996-10-11 Publication of NO963350L publication Critical patent/NO963350L/no

1999-07-12 Publication of NO305702B1 publication Critical patent/NO305702B1/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO963350A 1994-12-13 1996-08-12 3'-substituert nukleosid-derivat eller et av dets farmas°ytisk akseptable salter, anvendelse derav og medisinsk preparat NO305702B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP30891294		1994-12-13
JP20864595		1995-08-16
PCT/JP1995/002554 WO1996018636A1 (fr)	1994-12-13	1995-12-13	Derives de nucleoside substitues en 3'

Publications (3)

Publication Number	Publication Date
NO963350D0 NO963350D0 (no)	1996-08-12
NO963350L true NO963350L (no)	1996-10-11
NO305702B1 NO305702B1 (no)	1999-07-12

Family

ID=26516961

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO963350A NO305702B1 (no)	1994-12-13	1996-08-12	3'-substituert nukleosid-derivat eller et av dets farmas°ytisk akseptable salter, anvendelse derav og medisinsk preparat

Country Status (18)

Country	Link
US (2)	USRE38090E1 (no)
EP (1)	EP0747389B1 (no)
JP (1)	JP3142874B2 (no)
KR (1)	KR0177372B1 (no)
CN (1)	CN1195768C (no)
AT (1)	ATE249471T1 (no)
AU (1)	AU674639B2 (no)
CA (1)	CA2182707C (no)
DE (1)	DE69531729T2 (no)
DK (1)	DK0747389T3 (no)
ES (1)	ES2206522T3 (no)
FI (1)	FI118967B (no)
HU (1)	HU217772B (no)
NO (1)	NO305702B1 (no)
NZ (1)	NZ297100A (no)
PT (1)	PT747389E (no)
RU (1)	RU2130029C1 (no)
WO (1)	WO1996018636A1 (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
USRE38090E1 (en) *	1994-12-13	2003-04-22	Akira Matsuda	3′-substituted nucleoside derivative
CA2172471C (en) *	1995-03-29	1999-01-26	Hua Qi	Apparatus for and method of simulating ocular optical system
US6235776B1 (en)	1998-11-12	2001-05-22	Cell Pathways, Inc.	Method for treating a patient with neoplasia by treatment with a paclitaxel derivative
US6235782B1 (en)	1998-11-12	2001-05-22	Rifat Pamukcu	Method for treating a patient with neoplasia by treatment with a platinum coordination complex
MY164523A (en)	2000-05-23	2017-12-29	Univ Degli Studi Cagliari	Methods and compositions for treating hepatitis c virus
EA200601591A1 (ru)	2000-05-26	2007-02-27	Айденикс (Кайман) Лимитед	Применение рибонуклеозидных соединений для лечения флавивирусных и пестивирусных инфекций
WO2003026589A2 (en)	2001-09-28	2003-04-03	Idenix (Cayman) Limited	Methods and compositions for treating hepatitis c virus using 4'-modified nucleosides
US7012100B1 (en)	2002-06-04	2006-03-14	Avolix Pharmaceuticals, Inc.	Cell migration inhibiting compositions and methods and compositions for treating cancer
BR0312278A (pt) *	2002-06-28	2007-06-19	Idenix Cayman Ltd	éster 2'-c-metil-3'-o-l-valina de ribofuranosil citidina para tratamento de infecções por flaviviridae
CN101172993A (zh) *	2002-06-28	2008-05-07	埃迪尼克斯(开曼)有限公司	用于治疗黄病毒感染的2′－c－甲基－3′－o－l－缬氨酸酯核糖呋喃基胞苷
KR20050055630A (ko) *	2002-06-28	2005-06-13	이데닉스 (케이만) 리미티드	플라비비리다에 감염 치료를 위한 1'-, 2'- 및 3'-변형된뉴클레오시드 유도체
US7608600B2 (en) *	2002-06-28	2009-10-27	Idenix Pharmaceuticals, Inc.	Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
SI1576138T1 (sl)	2002-11-15	2017-07-31	Idenix Pharmaceuticals Llc	2'-metil nukleozidi v kombinaciji z interferon in flaviviridae mutacijo
US7598373B2 (en) *	2002-12-12	2009-10-06	Idenix Pharmaceuticals, Inc.	Process for the production of 2-C-methyl-D-ribonolactone
WO2005011709A1 (en) *	2003-02-19	2005-02-10	Yale University	Anti-viral nucleoside analogs and methods for treating viral infections, especially hiv infections
EP1912643A2 (en) *	2004-06-23	2008-04-23	Idenix (Cayman) Limited	5-aza-7-deazapurine derivatives for treating infections with flaviviridae
JP4516863B2 (ja) *	2005-03-11	2010-08-04	株式会社ケンウッド	音声合成装置、音声合成方法及びプログラム
EP1976382B1 (en) *	2005-12-23	2013-04-24	IDENIX Pharmaceuticals, Inc.	Process for preparing a synthetic intermediate for preparation of branched nucleosides
EP2045258B1 (en) *	2006-07-24	2011-09-21	Taiho Pharmaceutical Co., Ltd.	3'-ethynylcytidine derivative
JP5066737B2 (ja)	2007-04-06	2012-11-07	大鵬薬品工業株式会社	シチジン誘導体を含有する持続静脈内投与用抗腫瘍剤
JP4954004B2 (ja)	2007-08-09	2012-06-13	株式会社バイオダイナミクス研究所	任意の化合物が導入された新規核酸誘導体、及びその製造方法
EP2258378A4 (en)	2008-03-27	2012-01-04	Taiho Pharmaceutical Co Ltd	ANTICROBIAL AGENTS WITH A CYTIDINE DERIVATIVE AND CARBOPLATIN
EP2890704B1 (en)	2012-08-31	2018-02-28	Novartis AG	2'-ethynyl nucleoside derivatives for treatment of viral infections
JP7138351B2 (ja) *	2016-12-22	2022-09-16	キャリセラバイオサイエンシーズ，インコーポレイテッド	エクトヌクレオチダーゼ阻害剤およびその使用方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3480613A (en) *	1967-07-03	1969-11-25	Merck & Co Inc	2-c or 3-c-alkylribofuranosyl - 1-substituted compounds and the nucleosides thereof
FR2019943A1 (no) *	1968-10-04	1970-07-10	Esco Corp
DE3924424A1 (de) *	1989-07-24	1991-01-31	Boehringer Mannheim Gmbh	Nucleosid-derivate, verfahren zu deren herstellung, deren verwendung als arzneimittel sowie deren verwendung bei der nucleinsaeure-sequenzierung
DE4204032A1 (de) *	1992-02-12	1993-08-19	Boehringer Mannheim Gmbh	Neue liponucleotide, deren herstellunmg sowie deren verwendung als antivirale arzneimittel
WO1993018051A1 (en) *	1992-03-11	1993-09-16	Japan Tobacco Inc.	Process for producing nucleoside derivative
DE4418690A1 (de) *	1994-05-28	1996-01-11	Boehringer Mannheim Gmbh	Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel
US5681940A (en) *	1994-11-02	1997-10-28	Icn Pharmaceuticals	Sugar modified nucleosides and oligonucleotides
USRE38090E1 (en) *	1994-12-13	2003-04-22	Akira Matsuda	3′-substituted nucleoside derivative

1995
- 1995-12-13 US US09/584,171 patent/USRE38090E1/en not_active Expired - Lifetime
- 1995-12-13 CA CA002182707A patent/CA2182707C/en not_active Expired - Lifetime
- 1995-12-13 DK DK95940427T patent/DK0747389T3/da active
- 1995-12-13 RU RU96118248A patent/RU2130029C1/ru active
- 1995-12-13 ES ES95940427T patent/ES2206522T3/es not_active Expired - Lifetime
- 1995-12-13 PT PT95940427T patent/PT747389E/pt unknown
- 1995-12-13 AU AU41884/96A patent/AU674639B2/en not_active Expired
- 1995-12-13 AT AT95940427T patent/ATE249471T1/de active
- 1995-12-13 EP EP95940427A patent/EP0747389B1/en not_active Expired - Lifetime
- 1995-12-13 CN CNB95191605XA patent/CN1195768C/zh not_active Expired - Lifetime
- 1995-12-13 WO PCT/JP1995/002554 patent/WO1996018636A1/ja active IP Right Grant
- 1995-12-13 HU HU9602214A patent/HU217772B/hu unknown
- 1995-12-13 KR KR1019960704407A patent/KR0177372B1/ko not_active IP Right Cessation
- 1995-12-13 JP JP08518600A patent/JP3142874B2/ja not_active Expired - Lifetime
- 1995-12-13 NZ NZ297100A patent/NZ297100A/en not_active IP Right Cessation
- 1995-12-13 DE DE69531729T patent/DE69531729T2/de not_active Expired - Lifetime
- 1995-12-13 US US08/693,161 patent/US5763418A/en not_active Ceased
1996
- 1996-08-12 NO NO963350A patent/NO305702B1/no not_active IP Right Cessation
- 1996-08-12 FI FI963148A patent/FI118967B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
RU2130029C1 (ru)	1999-05-10
DK0747389T3 (da)	2004-01-26
WO1996018636A1 (fr)	1996-06-20
ATE249471T1 (de)	2003-09-15
AU674639B2 (en)	1997-01-02
NO305702B1 (no)	1999-07-12
CN1195768C (zh)	2005-04-06
CN1140453A (zh)	1997-01-15
HU217772B (hu)	2000-04-28
JP3142874B2 (ja)	2001-03-07
PT747389E (pt)	2003-12-31
EP0747389A1 (en)	1996-12-11
KR0177372B1 (ko)	1999-04-01
HUT75227A (en)	1997-04-28
DE69531729T2 (de)	2004-08-05
HU9602214D0 (en)	1996-11-28
FI963148A (fi)	1996-08-12
FI118967B (fi)	2008-05-30
KR970701198A (ko)	1997-03-17
CA2182707C (en)	2000-05-30
AU4188496A (en)	1996-07-03
NZ297100A (en)	1997-10-24
DE69531729D1 (de)	2003-10-16
FI963148A0 (fi)	1996-08-12
NO963350D0 (no)	1996-08-12
USRE38090E1 (en)	2003-04-22
EP0747389A4 (en)	1998-12-30
EP0747389B1 (en)	2003-09-10
ES2206522T3 (es)	2004-05-16
US5763418A (en)	1998-06-09

Legal Events

Date	Code	Title	Description
2015-12-21	MK1K	Patent expired

Publication	Publication Date	Title
NO963350D0 (no)	1996-08-12	"3'-substituert nukleosid-derivat
DK0536936T3 (da)	1997-01-13	Pyrimidinnukleosidderivater med anti-tumor-aktivitet, deres fremstilling og anvendelse
ES2118069T3 (es)	1998-09-16	Profarmacos de fosfonatos.
DK535789A (da)	1990-04-30	Pyrimidindionderivater, fremgangsmaade til fremstilling heraf og antiarytmika omfattende samme
PL351500A1 (en)	2003-04-22	Use of cytidine derivatives for the treatment of leukaemia
DE69814375D1 (de)	2003-06-12	Fungizide trifluoromethylalkylamino-triazolopyrimidine-derivate
NL300247I2 (nl)	2007-02-01	2-Halogeen-9-(2-desoxy-2-fluor-bêta-D-arabinofuranosyl)-adeninenucleosiderivaten.
ATE134644T1 (de)	1996-03-15	Weitere antivirale pyrimidin-nukleosiden
CA2117883A1 (en)	1993-12-09	Erythromycin derivatives
HUT62582A (en)	1993-05-28	Process for producing pyrimidine nucleoside derivatives and pharmaceutical compositions comprising same as active ingredient
YU47802A (sh)	2006-03-03	Postupci i kompozicije za levovirin
DE69813231T2 (de)	2003-12-04	Natürliche antitumor- oder antivirale substanzen und ihre anwendung
DE3683836D1 (de)	1992-03-19	Glucopyranose-derivate.
DE68901443D1 (de)	1992-06-11	Derivate von nukleosiden.
ES2164013A1 (es)	2002-02-01	Glicosidos de n-acetil-6-o-(2,2-bis(hidroximetil)-3-hidroxipropil)-d-glucosamina, procedimiento de obtencion y uso en el tratamiento de tumores cerebrales.