YU47802A - Postupci i kompozicije za levovirin - Google Patents
Postupci i kompozicije za levovirinInfo
- Publication number
- YU47802A YU47802A YU47802A YUP47802A YU47802A YU 47802 A YU47802 A YU 47802A YU 47802 A YU47802 A YU 47802A YU P47802 A YUP47802 A YU P47802A YU 47802 A YU47802 A YU 47802A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- compound
- compounds
- levovirin
- compositions
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/12—Triazine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Biomedical Technology (AREA)
- Environmental Sciences (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Microbiology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
Abstract
Dobijena su nukleozidna i nukleotidna jedinjenja i njihovi analozi/prolekovi. Naročito razmatrana jedinjenja uključuju 1-β-L-ribofuranozil-1,2,4-triazol-3-karboksamid, koji može biti modifikovan i/ili fosforilovan. Razmatrana jedinjenja mogu dalje biti kombinovana sa drugim farmakološkim jedinjenjima nariočito uključujući Ribavirin, antitela i citokine. Poželjne upotrebe jedinjenja uključuju upotrebu kao antivirusnog jedinjenja, anti-inflamatornog jedinjenja, antineoplastičnog jedinjenja i jedinjenja koje stimuliše rast ćelija.[Nucleoside and nucleotide compounds and their analogs/prodrugs are provided. Particularly contemplated compounds include 1-β-L-ribofuranosyl-1,2,4-triazole-3-carboxamide, which may be modified and/or phosphorylated. Contemplated compounds may further be combined with other pharmacological compounds, especially including Ribavirin, antibodies, and cytokines. Preferred uses of contemplated compounds include use as an antiviral compound, anti-inflammatory compound, antineoplastic compound, and as a compound to stimulate cellular growth.
Applications Claiming Priority (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17209799P | 1999-12-23 | 1999-12-23 | |
US17344699P | 1999-12-29 | 1999-12-29 | |
US17511100P | 2000-01-06 | 2000-01-06 | |
US19075800P | 2000-03-20 | 2000-03-20 | |
US22687500P | 2000-08-22 | 2000-08-22 | |
US22694700P | 2000-08-22 | 2000-08-22 | |
US23382300P | 2000-09-19 | 2000-09-19 | |
US23354800P | 2000-09-19 | 2000-09-19 | |
US23382200P | 2000-09-19 | 2000-09-19 | |
US23382100P | 2000-09-19 | 2000-09-19 | |
US23546500P | 2000-09-26 | 2000-09-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
YU47802A true YU47802A (sh) | 2006-03-03 |
Family
ID=27582702
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU47802A YU47802A (sh) | 1999-12-23 | 2000-12-19 | Postupci i kompozicije za levovirin |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP1244356A4 (sh) |
JP (1) | JP2003523957A (sh) |
KR (1) | KR20030032908A (sh) |
CN (1) | CN1420723A (sh) |
AU (1) | AU2442201A (sh) |
BR (1) | BR0016162A (sh) |
CA (1) | CA2384326A1 (sh) |
CZ (1) | CZ20022112A3 (sh) |
HK (1) | HK1049944A1 (sh) |
HR (1) | HRP20020485A2 (sh) |
HU (1) | HUP0300219A3 (sh) |
IL (1) | IL148514A0 (sh) |
MX (1) | MXPA02006251A (sh) |
NO (1) | NO20022969L (sh) |
NZ (1) | NZ517634A (sh) |
PL (1) | PL364927A1 (sh) |
SI (1) | SI20976A (sh) |
SK (1) | SK8612002A3 (sh) |
WO (1) | WO2001045509A1 (sh) |
YU (1) | YU47802A (sh) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI332507B (en) | 2002-11-19 | 2010-11-01 | Hoffmann La Roche | Antiviral nucleoside derivatives |
US6930093B2 (en) * | 2003-07-10 | 2005-08-16 | Valeant Research & Development | Use of ribofuranose derivatives against inflammatory bowel diseases |
EP1664074A2 (en) | 2003-09-11 | 2006-06-07 | F.Hoffmann-La Roche Ag | Polymorphic nucleoside compounds |
US20050182252A1 (en) | 2004-02-13 | 2005-08-18 | Reddy K. R. | Novel 2'-C-methyl nucleoside derivatives |
EA016830B1 (ru) * | 2006-09-11 | 2012-07-30 | Саузерн Рисерч Инститьют | Азольные нуклеозиды и их применение в качестве ингибиторов вариальных рнк- и днк-полимераз |
CN102952104A (zh) * | 2011-08-17 | 2013-03-06 | 黑龙江省松花江药业有限公司 | 一种呋喃类化合物 |
WO2015123352A1 (en) | 2014-02-13 | 2015-08-20 | Ligand Pharmaceuticals, Inc. | Prodrug compounds and their uses |
CN106687118A (zh) | 2014-07-02 | 2017-05-17 | 配体药物公司 | 前药化合物及其用途 |
CN104387431A (zh) * | 2014-10-24 | 2015-03-04 | 江南大学 | 一种高特异性的利巴韦林人工抗原的制备方法 |
EP3156050A1 (en) * | 2015-10-16 | 2017-04-19 | Universitat Autònoma De Barcelona | New combination therapies for treating neurological damage |
CN111788196A (zh) | 2018-01-09 | 2020-10-16 | 配体药物公司 | 缩醛化合物及其治疗用途 |
CN109528638B (zh) * | 2018-12-20 | 2021-07-06 | 江西润泽药业有限公司 | 利巴韦林衍生物制剂及其制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3798209A (en) * | 1971-06-01 | 1974-03-19 | Icn Pharmaceuticals | 1,2,4-triazole nucleosides |
ATE135914T1 (de) * | 1986-03-27 | 1996-04-15 | Gensia Inc | Aica riboside zur prophylaktischen behandlung von krankheiten mit einer verminderten durchblutung. |
GB9019812D0 (en) * | 1990-09-11 | 1990-10-24 | Scotgen Ltd | Novel antibodies for treatment and prevention of infection in animals and man |
US6387365B1 (en) * | 1995-05-19 | 2002-05-14 | Schering Corporation | Combination therapy for chronic hepatitis C infection |
WO1997021452A2 (en) * | 1995-12-14 | 1997-06-19 | Advanced Magnetics, Inc. | Macromolecular prodrugs of nucleotide analogs |
CZ120699A3 (cs) * | 1996-10-16 | 1999-09-15 | Icn Pharmaceuticals, Inc. | Monocyklická L-nukleosidová analoga a jejich využití |
SK288038B6 (en) * | 1998-05-15 | 2013-01-02 | Merck Sharp & Dohme | Use of ribavirin and interferon alpha for manufacture pharmaceutical compositions for treating chronic hepatitis C infection |
US6277830B1 (en) * | 1998-10-16 | 2001-08-21 | Schering Corporation | 5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon |
AU2026900A (en) * | 1998-11-20 | 2000-06-13 | Salk Institute For Biological Studies, The | Neuron stimulation by ribavirin, and analogs thereof |
-
2000
- 2000-12-19 KR KR1020027008069A patent/KR20030032908A/ko not_active Application Discontinuation
- 2000-12-19 JP JP2001546256A patent/JP2003523957A/ja active Pending
- 2000-12-19 SK SK861-2002A patent/SK8612002A3/sk not_active Application Discontinuation
- 2000-12-19 SI SI200020047A patent/SI20976A/sl not_active IP Right Cessation
- 2000-12-19 HU HU0300219A patent/HUP0300219A3/hu unknown
- 2000-12-19 MX MXPA02006251A patent/MXPA02006251A/es unknown
- 2000-12-19 IL IL14851400A patent/IL148514A0/xx unknown
- 2000-12-19 AU AU24422/01A patent/AU2442201A/en not_active Abandoned
- 2000-12-19 NZ NZ517634A patent/NZ517634A/en not_active Application Discontinuation
- 2000-12-19 EP EP00988189A patent/EP1244356A4/en not_active Withdrawn
- 2000-12-19 YU YU47802A patent/YU47802A/sh unknown
- 2000-12-19 CZ CZ20022112A patent/CZ20022112A3/cs unknown
- 2000-12-19 PL PL00364927A patent/PL364927A1/xx not_active Application Discontinuation
- 2000-12-19 WO PCT/US2000/034605 patent/WO2001045509A1/en not_active Application Discontinuation
- 2000-12-19 BR BR0016162-4A patent/BR0016162A/pt not_active IP Right Cessation
- 2000-12-19 CN CN00817416A patent/CN1420723A/zh active Pending
- 2000-12-19 CA CA002384326A patent/CA2384326A1/en not_active Abandoned
-
2002
- 2002-06-03 HR HR20020485A patent/HRP20020485A2/hr not_active Application Discontinuation
- 2002-06-20 NO NO20022969A patent/NO20022969L/no not_active Application Discontinuation
-
2003
- 2003-03-28 HK HK03102255.3A patent/HK1049944A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP1244356A1 (en) | 2002-10-02 |
HK1049944A1 (zh) | 2003-06-06 |
WO2001045509A1 (en) | 2001-06-28 |
CA2384326A1 (en) | 2001-06-28 |
CZ20022112A3 (cs) | 2003-05-14 |
NO20022969D0 (no) | 2002-06-20 |
PL364927A1 (en) | 2004-12-27 |
HRP20020485A2 (en) | 2005-10-31 |
HUP0300219A2 (hu) | 2003-06-28 |
NZ517634A (en) | 2004-06-25 |
MXPA02006251A (es) | 2003-01-28 |
SI20976A (sl) | 2003-02-28 |
JP2003523957A (ja) | 2003-08-12 |
IL148514A0 (en) | 2002-09-12 |
BR0016162A (pt) | 2002-08-13 |
CN1420723A (zh) | 2003-05-28 |
EP1244356A4 (en) | 2003-03-19 |
KR20030032908A (ko) | 2003-04-26 |
HUP0300219A3 (en) | 2005-07-28 |
AU2442201A (en) | 2001-07-03 |
NO20022969L (no) | 2002-06-20 |
SK8612002A3 (en) | 2003-03-04 |
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