NO913176L - Morfolinylderivater av doxorubicin og deres fremstilling. - Google Patents
Morfolinylderivater av doxorubicin og deres fremstilling.Info
- Publication number
- NO913176L NO913176L NO91913176A NO913176A NO913176L NO 913176 L NO913176 L NO 913176L NO 91913176 A NO91913176 A NO 91913176A NO 913176 A NO913176 A NO 913176A NO 913176 L NO913176 L NO 913176L
- Authority
- NO
- Norway
- Prior art keywords
- doxorubicin
- preparation
- morpholinyl derivatives
- morpholinyl
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/313—Compounds having groups containing halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO940831A NO176911C (no) | 1989-12-19 | 1994-03-09 | Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898928654A GB8928654D0 (en) | 1989-12-19 | 1989-12-19 | Preparation of 2-methoxy-4-morpholinyl anthracyclines |
GB909007513A GB9007513D0 (en) | 1990-04-03 | 1990-04-03 | Morpholinyl derivatives of doxorubicin and process for their preparation |
PCT/EP1990/002229 WO1991009046A1 (en) | 1989-12-19 | 1990-12-18 | Morpholinyl derivatives of doxorubicin and process for their preparation |
Publications (4)
Publication Number | Publication Date |
---|---|
NO913176L true NO913176L (no) | 1991-08-14 |
NO913176D0 NO913176D0 (no) | 1991-08-14 |
NO175533B NO175533B (no) | 1994-07-18 |
NO175533C NO175533C (no) | 1994-10-26 |
Family
ID=26296395
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO913176A NO175533C (no) | 1989-12-19 | 1991-08-14 | Fremstilling av morfolinylderivater av doxorubicin |
NO940831A NO176911C (no) | 1989-12-19 | 1994-03-09 | Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO940831A NO176911C (no) | 1989-12-19 | 1994-03-09 | Diiodforbindelser for anvendelse ved fremstilling av morfolinylderivater av doxorubicin, og deres fremstilling |
Country Status (28)
Country | Link |
---|---|
EP (1) | EP0434960B1 (no) |
JP (1) | JP3300342B2 (no) |
KR (1) | KR0183033B1 (no) |
CN (2) | CN1024922C (no) |
AT (1) | ATE143023T1 (no) |
AU (1) | AU636429B2 (no) |
CA (1) | CA2046857C (no) |
CZ (1) | CZ281949B6 (no) |
DE (1) | DE69028610T2 (no) |
DK (1) | DK0434960T3 (no) |
ES (1) | ES2094136T3 (no) |
FI (1) | FI97389C (no) |
GR (1) | GR3021557T3 (no) |
HR (1) | HRP921226B1 (no) |
HU (2) | HU208148B (no) |
IE (1) | IE81174B1 (no) |
IL (3) | IL111527A (no) |
MY (1) | MY119192A (no) |
NO (2) | NO175533C (no) |
NZ (1) | NZ243695A (no) |
PT (1) | PT96226B (no) |
RU (1) | RU2100366C1 (no) |
SI (1) | SI9012379B (no) |
SK (1) | SK621990A3 (no) |
TW (1) | TW208019B (no) |
UA (1) | UA27108A1 (no) |
WO (1) | WO1991009046A1 (no) |
YU (1) | YU48136B (no) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5843903A (en) * | 1995-11-27 | 1998-12-01 | The Administrators Of The Tulane Educational Fund | Targeted cytotoxic anthracycline analogs |
DE60031793T2 (de) * | 1999-12-29 | 2007-08-23 | Immunogen Inc., Cambridge | Doxorubicin- und daunorubicin-enthaltende, zytotoxische mittel und deren therapeutische anwendung |
AU2003234670B2 (en) | 2002-05-24 | 2010-06-10 | Angiotech International Ag | Compositions and methods for coating medical implants |
MXPA05003183A (es) | 2002-09-26 | 2005-06-08 | Angiotech Int Ag | Evolturas perivasculares. |
EP1594459B1 (en) | 2002-12-30 | 2010-02-17 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
WO2004082689A1 (en) * | 2003-03-18 | 2004-09-30 | Pharmacia Italia Spa | Combined therapy comprising nemorubicin and a cyclooxygenase-2-inhibitor |
US20100069317A1 (en) * | 2006-07-12 | 2010-03-18 | Nerviano Medical Sciences S.R.L. | Crystalline nemorubicin hydrochloride |
EP2277884B1 (en) * | 2008-04-11 | 2017-08-23 | Tianjin Hemay Oncology Pharmaceutical Co., Ltd | Anthracycline antibiotic derivatives with high activity, preparation methods and uses thereof |
CN101353361B (zh) * | 2008-08-08 | 2011-06-01 | 中国人民解放军第四军医大学 | 一种阿霉素前体药物的制备方法及其应用 |
CA2818713C (en) * | 2010-12-02 | 2019-03-26 | Nerviano Medical Sciences S.R.L. | Process for the preparation of morpholinyl anthracycline derivatives |
WO2014177441A1 (en) | 2013-04-29 | 2014-11-06 | Nerviano Medical Sciences S.R.L. | New morpholinyl anthracycline derivatives |
EP3084445B1 (en) | 2013-12-11 | 2020-10-28 | University of Massachusetts | Compositions and methods for treating disease using salmonella t3ss effector protein (sipa) |
ES2735375T3 (es) | 2014-11-05 | 2019-12-18 | Nerviano Medical Sciences Srl | Derivados funcionalizados de morfolinil antraciclina |
CN115043895A (zh) * | 2022-07-15 | 2022-09-13 | 戊言医药科技(上海)有限公司 | 一种pnu-159682及其中间体的制备方法 |
WO2024038065A1 (en) * | 2022-08-15 | 2024-02-22 | Synaffix B.V. | Anthracyclins and conjugates thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2883443A (en) * | 1956-07-13 | 1959-04-21 | Ruetschi Karl | Lead-acid storage battery |
US4423123A (en) * | 1980-04-17 | 1983-12-27 | Shin-Kobe Electric Machinery Co., Ltd. | Electric storage battery and a method of making the same |
JPS57163393A (en) * | 1981-03-27 | 1982-10-07 | Microbial Chem Res Found | Novel anthracyclin derivative and its preparation |
US4363857A (en) * | 1981-10-16 | 1982-12-14 | General Motors Corporation | Laminated metal-plastic battery grid |
US4710564A (en) * | 1985-01-18 | 1987-12-01 | Microbial Chemistry Research Foundation | Anthracycline compounds |
GB2172594B (en) * | 1985-03-22 | 1988-06-08 | Erba Farmitalia | New morpholino derivatives of daunorubicin and doxorubicin |
JPS6215323A (ja) * | 1986-02-14 | 1987-01-23 | Dainippon Ink & Chem Inc | 微多孔中空繊維の製造法 |
US4861836A (en) * | 1986-12-23 | 1989-08-29 | Daikin Industries Ltd. | Novel, iodine-containing compound, preparation thereof and block copolymer comprising the same |
-
1990
- 1990-11-15 ES ES90121905T patent/ES2094136T3/es not_active Expired - Lifetime
- 1990-11-15 DK DK90121905.5T patent/DK0434960T3/da active
- 1990-11-15 AT AT90121905T patent/ATE143023T1/de not_active IP Right Cessation
- 1990-11-15 DE DE69028610T patent/DE69028610T2/de not_active Expired - Fee Related
- 1990-11-15 EP EP90121905A patent/EP0434960B1/en not_active Expired - Lifetime
- 1990-12-12 CZ CS906219A patent/CZ281949B6/cs not_active IP Right Cessation
- 1990-12-12 NZ NZ243695A patent/NZ243695A/xx unknown
- 1990-12-12 SK SK6219-90A patent/SK621990A3/sk unknown
- 1990-12-12 IL IL111527A patent/IL111527A/en not_active IP Right Cessation
- 1990-12-12 IL IL9664390A patent/IL96643A/en not_active IP Right Cessation
- 1990-12-14 TW TW079110518A patent/TW208019B/zh active
- 1990-12-17 MY MYPI94001426A patent/MY119192A/en unknown
- 1990-12-17 YU YU237990A patent/YU48136B/sh unknown
- 1990-12-17 SI SI9012379A patent/SI9012379B/sl not_active IP Right Cessation
- 1990-12-17 IE IE454390A patent/IE81174B1/en not_active IP Right Cessation
- 1990-12-17 PT PT96226A patent/PT96226B/pt not_active IP Right Cessation
- 1990-12-18 KR KR1019910700930A patent/KR0183033B1/ko not_active IP Right Cessation
- 1990-12-18 CN CN90110144A patent/CN1024922C/zh not_active Expired - Fee Related
- 1990-12-18 WO PCT/EP1990/002229 patent/WO1991009046A1/en active IP Right Grant
- 1990-12-18 AU AU69194/91A patent/AU636429B2/en not_active Ceased
- 1990-12-18 HU HU912994A patent/HU208148B/hu not_active IP Right Cessation
- 1990-12-18 CA CA002046857A patent/CA2046857C/en not_active Expired - Fee Related
- 1990-12-18 RU SU915001540A patent/RU2100366C1/ru not_active IP Right Cessation
- 1990-12-18 UA UA5001540A patent/UA27108A1/uk unknown
- 1990-12-18 JP JP50124491A patent/JP3300342B2/ja not_active Expired - Fee Related
- 1990-12-18 HU HU9200656A patent/HU209433B/hu unknown
-
1991
- 1991-08-14 NO NO913176A patent/NO175533C/no unknown
- 1991-08-16 FI FI913887A patent/FI97389C/fi active
-
1992
- 1992-11-11 HR HRP-2379/90A patent/HRP921226B1/xx not_active IP Right Cessation
-
1993
- 1993-03-05 CN CN93102413A patent/CN1039708C/zh not_active Expired - Fee Related
-
1994
- 1994-03-09 NO NO940831A patent/NO176911C/no unknown
- 1994-11-04 IL IL11152794A patent/IL111527A0/xx unknown
-
1996
- 1996-11-06 GR GR960402934T patent/GR3021557T3/el unknown
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