NO812311L - Bronchospasmolytisk virksomme forbindelser og fremgangsmaate for deres fremstilling - Google Patents

Bronchospasmolytisk virksomme forbindelser og fremgangsmaate for deres fremstilling

Info

Publication number
NO812311L
NO812311L NO812311A NO812311A NO812311L NO 812311 L NO812311 L NO 812311L NO 812311 A NO812311 A NO 812311A NO 812311 A NO812311 A NO 812311A NO 812311 L NO812311 L NO 812311L
Authority
NO
Norway
Prior art keywords
sup
sub
group
preparation
groups containing
Prior art date
Application number
NO812311A
Other languages
English (en)
Other versions
NO152130C (no
NO152130B (no
Inventor
Otto Agne Torsten Olsson
Leif Aake Svensson
Kjell Ingvar Leopold Wetterlin
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Publication of NO812311L publication Critical patent/NO812311L/no
Priority to NO841882A priority Critical patent/NO156897C/no
Publication of NO152130B publication Critical patent/NO152130B/no
Publication of NO152130C publication Critical patent/NO152130C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Luminescent Compositions (AREA)
NO812311A 1980-07-09 1981-07-07 Analogifremgangsmaate for fremstilling av bronchospasmolytisk virksomme forbindelser NO152130C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO841882A NO156897C (no) 1980-07-09 1984-05-10 Mellomprodukter for bruk ved fremstilling av bronkospasmolytisk virksomme forbindelser.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8022439 1980-07-09
GB8116441 1981-05-29

Publications (3)

Publication Number Publication Date
NO812311L true NO812311L (no) 1982-01-11
NO152130B NO152130B (no) 1985-04-29
NO152130C NO152130C (no) 1985-08-07

Family

ID=26276161

Family Applications (2)

Application Number Title Priority Date Filing Date
NO812311A NO152130C (no) 1980-07-09 1981-07-07 Analogifremgangsmaate for fremstilling av bronchospasmolytisk virksomme forbindelser
NO1996008C NO1996008I1 (no) 1980-07-09 1996-06-27 Bambuterol

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO1996008C NO1996008I1 (no) 1980-07-09 1996-06-27 Bambuterol

Country Status (29)

Country Link
US (2) US4419364A (no)
EP (1) EP0043807B1 (no)
KR (3) KR850000301B1 (no)
AT (1) ATE7689T1 (no)
AU (1) AU539976B2 (no)
CA (1) CA1180021A (no)
CS (1) CS221845B2 (no)
CY (1) CY1273A (no)
DD (1) DD202001A5 (no)
DE (1) DE3163871D1 (no)
DK (1) DK157678C (no)
ES (3) ES8300678A1 (no)
FI (1) FI73666C (no)
GR (1) GR74291B (no)
HK (1) HK5385A (no)
HU (2) HU184959B (no)
IE (1) IE51373B1 (no)
IS (1) IS1262B6 (no)
LU (1) LU88304I2 (no)
MX (1) MX9203239A (no)
MY (1) MY8700026A (no)
NO (2) NO152130C (no)
NZ (1) NZ197628A (no)
PH (2) PH16535A (no)
PL (1) PL128513B1 (no)
PT (1) PT73336B (no)
SG (1) SG79784G (no)
SU (1) SU1128830A3 (no)
YU (3) YU42116B (no)

Families Citing this family (34)

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SE8904064D0 (sv) * 1989-12-01 1989-12-01 Astra Ab Improved method of preparing an intermediate for the manufacture of bambuterol
SE9000948D0 (sv) * 1990-03-16 1990-03-16 Draco Ab New use
US5830422A (en) * 1995-06-23 1998-11-03 Ormiston Mining And Smelting Co. Ltd. Method for production of sodium bicarbonate, sodium carbonate and ammonium sulfate from sodium sulfate
CA2247953A1 (en) * 1996-01-29 1997-07-31 E. Charles Pesterfield Jr. Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists
SE9604752D0 (sv) * 1996-12-20 1996-12-20 Astra Ab Formulation and use
KR20030085658A (ko) * 2002-04-30 2003-11-07 한올제약주식회사 밤부테롤의 개선된 합성방법
US7495028B2 (en) * 2002-08-08 2009-02-24 Wen Tan R-bambuterol, its preparation and therapeutic uses
JP4979889B2 (ja) * 2002-08-08 2012-07-18 タン，ダブリュー． Ｒ型バンブテロール又はその薬学的に許容される塩の製造方法
CA2537185A1 (en) * 2003-08-29 2005-03-10 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type-iv
US20070259874A1 (en) * 2003-11-26 2007-11-08 Palle Venkata P Phosphodiesterase Inhibitors
WO2006081986A1 (en) * 2005-02-07 2006-08-10 F.Hoffmann-La Roche Ag Bambuterol and integrin inhibitor combination
WO2007031838A1 (en) 2005-09-16 2007-03-22 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
JP2009512677A (ja) * 2005-10-19 2009-03-26 ランバクシー ラボラトリーズ リミテッド ホスホジエステラーゼタイプｉｖ阻害剤の組成物
RU2008119323A (ru) 2005-10-19 2009-11-27 Рэнбакси Лабораториз Лимитед (In) Фармацевтические композиции мускаринового рецептора
SG174089A1 (en) * 2006-08-22 2011-09-29 Ranbaxy Lab Ltd Matrix metalloproteinase inhibitors
EP2066661A2 (en) * 2006-09-22 2009-06-10 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
EA200900472A1 (ru) * 2006-09-22 2009-10-30 Ранбакси Лабораторис Лимитед Ингибиторы фосфодиэстеразы iv типа
EP1958947A1 (en) 2007-02-15 2008-08-20 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type 4
EP2124943A1 (en) * 2007-03-14 2009-12-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b]pyridine derivatives as phosphodiesterase inhibitors
CA2680625C (en) 2007-03-14 2016-02-23 Ranbaxy Laboratories Limited Pyrazolo (3, 4-b) pyridine derivatives as phosphodiesterase inhibitors
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
WO2012014114A1 (en) 2010-07-30 2012-02-02 Ranbaxy Laboratories Limited Matrix metalloproteinase inhibitors
MX2013003364A (es) 2010-09-24 2013-06-05 Ranbaxy Lab Ltd Inhibidores de metaloproteinasa de matriz.
CN104854093B (zh) 2012-12-03 2016-10-12 辉瑞大药厂 新的选择性雄激素受体调节剂
WO2014108449A1 (en) 2013-01-08 2014-07-17 Atrogi Ab A screening method, a kit, a method of treatment and a compound for use in a method of treatment
CN104557614B (zh) * 2014-12-15 2017-01-04 广东东阳光药业有限公司 一种胺的还原方法
CN105622461B (zh) * 2016-01-29 2018-06-19 华南理工大学 一种化合物及其制备方法与应用
CN105859589B (zh) * 2016-04-05 2018-09-28 深圳市康立生生物科技有限公司 一种制备班布特罗杂质c的方法
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
CN109942462B (zh) * 2019-03-06 2022-01-14 宏冠生物药业有限公司 一种盐酸班布特罗的合成工艺
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

Family Cites Families (30)

* Cited by examiner, † Cited by third party
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SE178032C1 (no) 1961-01-01
DE1643488U (de) 1949-11-28 1952-09-11 G E Hilge Fa Brutgeraet.
DK85789C (da) 1955-07-05 1958-06-30 Cilag Ag Fremgangsmåde til fremstilling af d,1- eller 1-isopropyl-aminometyl-(3,4-dihydroksy-fenyl)-karbinol eller salte deraf.
DE1768167U (de) 1958-04-02 1958-06-04 Artur O Herrmann Warngeraet bei strassenhindernissen.
DE1275069B (de) 1960-02-15 1968-08-14 Boehringer Sohn Ingelheim 1-(3', 5'-Dihydroxyphenyl)-1-hydroxy-2-isopropylaminoalkane und Verfahren zu ihrer Herstellung
NL123439C (no) 1961-09-14
FR1324857A (fr) * 1962-06-14 1963-04-19 Chemie Linz Ag Procédé pour la préparation de dérivés de la phényléthanolamine
GB1141606A (en) 1965-04-12 1969-01-29 Rech S Et D Applic Scient Et M Improvements in alkyl ethers of substituted phenylaminoethanols
DE1543372A1 (de) 1966-10-18 1971-04-01 Boehringer Sohn Ingelheim Verfahren zur Herstellung von o-substituierten 3,4-Dioxyphenylalkanolaminen
US3937838A (en) * 1966-10-19 1976-02-10 Aktiebolaget Draco Orally active bronchospasmolytic compounds and their preparation
NO132866C (no) 1966-10-19 1976-01-21 Draco Ab
SE358633B (no) 1966-10-19 1973-08-06 Draco Ab
SE335359B (no) 1966-10-19 1971-05-24 Draco Ab
FR6087M (no) 1967-01-10 1968-06-04
SE369299B (no) 1967-10-18 1974-08-19 Draco Ab
SE338324B (no) 1967-12-19 1971-09-06 Haessle Ab
NO129903B (no) 1969-04-01 1974-06-10 Sterling Drug Inc
AT294046B (de) 1969-07-08 1971-11-10 Chemie Linz Ag Verfahren zur Herstellung des N,N'-Bis[2-(3',4'-dihydroxyphenyl)-2-hydroxyäthyl]-hexamethylendiamins, seiner optisch aktiven Formen und der Salze derselben
US3657319A (en) * 1970-05-05 1972-04-18 Smith Kline French Lab Alpha-aminoalkyl-4-hydroxy-3-carboalkoxyaminobenzyl alcohols
NO126437B (no) 1970-08-05 1973-02-05 Draco Ab
NL7112938A (no) 1970-09-30 1972-04-05
CH550771A (de) 1970-10-30 1974-06-28 Hoffmann La Roche Verfahren zur herstellung von phenaethylaminderivaten.
US3876679A (en) 1970-12-09 1975-04-08 Aldrich Chem Co Inc Di-substituted phenethylcarbamic acid esters
FI55988C (fi) 1971-10-19 1979-11-12 Klinge Co Chem Pharm Fab Foerfarande foer framstaellning av terapeutiskt anvaendbara o-acylfenoletanolaminer
US4011258A (en) 1973-06-21 1977-03-08 Aktiebolaget Draco Orally active bronchospasmolytic compounds
FI56673C (fi) 1974-03-29 1981-02-04 Huhtamaeki Yhthymae Oy Nytt foerfarande foer framstaellning av alfa-tert-bytylaminometyl-4-hydroxy-m-xylen-alfa1 alfa3-diol
JPS556625B2 (no) * 1974-05-16 1980-02-18
US4063025A (en) * 1975-02-05 1977-12-13 Yamanouchi Pharmaceutical Co., Ltd. 4-Substituted amino-α-aminomethylbenzyl alcohol derivatives
SE7510988L (sv) 1975-10-01 1977-04-02 Draco Ab Nya farmaceutiskt aktiva foreningar
DE2710997C3 (de) * 1977-03-14 1980-08-14 Dr. Karl Thomae Gmbh, 7950 Biberach 4-Alkoxy carbonylamino-phenyläthanolamine, deren Herstellung und deren Verwendung als Arzneimittel

Also Published As

Publication number Publication date
SU1128830A3 (ru) 1984-12-07
NO152130C (no) 1985-08-07
HU184959B (en) 1984-11-28
HK5385A (en) 1985-01-25
DE3163871D1 (en) 1984-07-05
CA1180021A (en) 1984-12-27
FI73666C (fi) 1987-11-09
LU88304I2 (fr) 1994-05-04
YU43168B (en) 1989-04-30
IE811522L (en) 1982-01-09
YU86383A (en) 1983-12-31
SG79784G (en) 1985-04-26
NO1996008I1 (no) 1996-06-27
HU187611B (en) 1986-02-28
IS2657A7 (is) 1982-01-10
AU7261881A (en) 1982-01-14
GR74291B (no) 1984-06-21
MX9203239A (es) 1992-07-01
YU170481A (en) 1983-12-31
DK157678C (da) 1990-06-18
FI812158L (fi) 1982-01-10
EP0043807B1 (en) 1984-05-30
IE51373B1 (en) 1986-12-10
KR830006174A (ko) 1983-09-20
PL128513B1 (en) 1984-02-29
KR850000870B1 (ko) 1985-06-22
DD202001A5 (de) 1983-08-24
US4419364A (en) 1983-12-06
ES8304072A1 (es) 1983-02-16
US4451663A (en) 1984-05-29
DK303481A (da) 1982-01-10
ATE7689T1 (de) 1984-06-15
IS1262B6 (is) 1987-03-27
ES503768A0 (es) 1982-11-01
PT73336B (en) 1983-09-01
EP0043807A2 (en) 1982-01-13
PH16535A (en) 1983-11-10
YU42116B (en) 1988-04-30
KR850002740A (ko) 1985-05-15
AU539976B2 (en) 1984-10-25
CS221845B2 (en) 1983-04-29
KR850000301B1 (ko) 1985-03-18
MY8700026A (en) 1987-12-31
NO152130B (no) 1985-04-29
ES8304534A1 (es) 1983-03-01
EP0043807A3 (en) 1982-09-22
FI73666B (fi) 1987-07-31
ES513109A0 (es) 1983-03-01
DK157678B (da) 1990-02-05
NZ197628A (en) 1985-07-12
YU43169B (en) 1989-04-30
PT73336A (en) 1981-08-01
CY1273A (en) 1985-03-08
PH19447A (en) 1986-04-18
KR850000871B1 (ko) 1985-06-22
ES8300678A1 (es) 1982-11-01
KR850002741A (ko) 1985-05-15
PL232108A1 (no) 1982-08-02
ES513108A0 (es) 1983-02-16
YU86483A (en) 1983-12-31

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