GB1141606A - Improvements in alkyl ethers of substituted phenylaminoethanols - Google Patents
Improvements in alkyl ethers of substituted phenylaminoethanolsInfo
- Publication number
- GB1141606A GB1141606A GB15501/65A GB1550165A GB1141606A GB 1141606 A GB1141606 A GB 1141606A GB 15501/65 A GB15501/65 A GB 15501/65A GB 1550165 A GB1550165 A GB 1550165A GB 1141606 A GB1141606 A GB 1141606A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- oxides
- april
- bases
- heterocyclic bases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
1,141,606. Basic ethers. SOC. D'ETUDES DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES ET MEDICALES. 4 April, 1966 [12 April, 1965], No. 15501/65. Heading C2C. Racemic and optically active compounds of the general formula (R = C 4 _ 12 alkyl, R 1 , 2 = H, halogen, C 1-4 alkyl, C 1-4 alkoxy or cycloalkyl having up to 6 carbon atoms, R 3 = H and R 4 = benzyl or -NR 3 R 4 = 1-pyrrolidinyl, piperidino, 1- piperazinyl or morpholino, optionally substituted by one or more C 1-4 alkyl or hydroxyalkyl radicals), N-oxides of the heterocyclic bases, acid addition salts of the bases and N-oxides and quaternary ammonium salts of the heterocyclic bases and N-oxides derived from alkyl halides and dialkyl sulphates are prepared by (a) etherification or (b) reacting the corresponding #-alkoxyphenethyl bromide with R 3 R 4 NH, optionally followed in either case by oxidation and/or salt formation. The preparation of alcohol starting materials for process (a) is described. The compounds of the invention exhibit varied pharmacological activity, and may be administered in the form of pharmaceutical preparations containing them together with a carrier.
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB15501/65A GB1141606A (en) | 1965-04-12 | 1965-04-12 | Improvements in alkyl ethers of substituted phenylaminoethanols |
BE678973D BE678973A (en) | 1965-04-12 | 1966-04-04 | |
FR56780A FR5935M (en) | 1965-04-12 | 1966-04-07 | |
ES0325355A ES325355A1 (en) | 1965-04-12 | 1966-04-09 | Procedure for the preparation of alternative etheries of fenilaminoetanol. (Machine-translation by Google Translate, not legally binding) |
CH526666A CH463538A (en) | 1965-04-12 | 1966-04-12 | Process for the preparation of new alkyl ethers of phenylaminoethanol |
NL6604841A NL6604841A (en) | 1965-04-12 | 1966-04-12 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB15501/65A GB1141606A (en) | 1965-04-12 | 1965-04-12 | Improvements in alkyl ethers of substituted phenylaminoethanols |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1141606A true GB1141606A (en) | 1969-01-29 |
Family
ID=10060250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB15501/65A Expired GB1141606A (en) | 1965-04-12 | 1965-04-12 | Improvements in alkyl ethers of substituted phenylaminoethanols |
Country Status (6)
Country | Link |
---|---|
BE (1) | BE678973A (en) |
CH (1) | CH463538A (en) |
ES (1) | ES325355A1 (en) |
FR (1) | FR5935M (en) |
GB (1) | GB1141606A (en) |
NL (1) | NL6604841A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0026298A1 (en) * | 1979-08-16 | 1981-04-08 | American Cyanamid Company | Method for promoting growth and reducing fat in animals using phenylethanolamine derivatives |
EP0049728A2 (en) * | 1980-08-25 | 1982-04-21 | American Cyanamid Company | Method for enhancing the growth rate of meat-producing animals and for improving the lean meat to fat ratio thereof |
US4419364A (en) | 1980-07-09 | 1983-12-06 | Aktiebolaget Draco | Bronchospasmolytic carbamate derivatives |
-
1965
- 1965-04-12 GB GB15501/65A patent/GB1141606A/en not_active Expired
-
1966
- 1966-04-04 BE BE678973D patent/BE678973A/xx unknown
- 1966-04-07 FR FR56780A patent/FR5935M/fr not_active Expired
- 1966-04-09 ES ES0325355A patent/ES325355A1/en not_active Expired
- 1966-04-12 CH CH526666A patent/CH463538A/en unknown
- 1966-04-12 NL NL6604841A patent/NL6604841A/xx unknown
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0026298A1 (en) * | 1979-08-16 | 1981-04-08 | American Cyanamid Company | Method for promoting growth and reducing fat in animals using phenylethanolamine derivatives |
US4419364A (en) | 1980-07-09 | 1983-12-06 | Aktiebolaget Draco | Bronchospasmolytic carbamate derivatives |
EP0049728A2 (en) * | 1980-08-25 | 1982-04-21 | American Cyanamid Company | Method for enhancing the growth rate of meat-producing animals and for improving the lean meat to fat ratio thereof |
EP0049728A3 (en) * | 1980-08-25 | 1982-08-04 | American Cyanamid Company | Phenylethane derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals, improving the efficiency of feed utilization thereby and/or improving the lean meat to fat ratio thereof |
Also Published As
Publication number | Publication date |
---|---|
NL6604841A (en) | 1966-10-13 |
CH463538A (en) | 1968-10-15 |
BE678973A (en) | 1966-09-16 |
FR5935M (en) | 1968-04-08 |
ES325355A1 (en) | 1967-04-01 |
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