NO333265B3 - Substituerte dihydrokinazoliner, fremgangsmåte for fremstilling derav, anvendelse av en slik forbindelse samt medikament inneholdende denne. - Google Patents

Substituerte dihydrokinazoliner, fremgangsmåte for fremstilling derav, anvendelse av en slik forbindelse samt medikament inneholdende denne.

Info

Publication number
NO333265B3
NO333265B3 NO20055649A NO20055649A NO333265B3 NO 333265 B3 NO333265 B3 NO 333265B3 NO 20055649 A NO20055649 A NO 20055649A NO 20055649 A NO20055649 A NO 20055649A NO 333265 B3 NO333265 B3 NO 333265B3
Authority
NO
Norway
Prior art keywords
compound
preparation
drug containing
dihydroquinazolines
substituted
Prior art date
Application number
NO20055649A
Other languages
English (en)
Other versions
NO20055649L (no
NO20055649D0 (no
NO333265B1 (no
Inventor
Rudolf Schohe-Loop
Rolf Grosser
Kerstin Henninger
Jörg Keldenich
Thomas Lampe
Holger Zimmermann
Tobias Wunberg
Judith Baumeister
Ulrich Betz
Mario Jeske
Susanne Nikolic
Jürgen Reefschlager
Frank Süssmeier
Guy Hewlett
Dieter Lang
Peter Nell
Original Assignee
Aicuris Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aicuris Gmbh & Co Kg filed Critical Aicuris Gmbh & Co Kg
Publication of NO20055649D0 publication Critical patent/NO20055649D0/no
Publication of NO20055649L publication Critical patent/NO20055649L/no
Publication of NO333265B1 publication Critical patent/NO333265B1/no
Publication of NO333265B3 publication Critical patent/NO333265B3/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/78Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20055649A 2003-05-02 2005-11-30 Substituerte dihydrokinazoliner, fremgangsmåte for fremstilling derav, anvendelse av en slik forbindelse samt medikament inneholdende denne. NO333265B3 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10319612A DE10319612A1 (de) 2003-05-02 2003-05-02 Substituierte Dihydrochinazoline
PCT/EP2004/004103 WO2004096778A1 (de) 2003-05-02 2004-04-17 Substituierte dihydrochinazoline mit antiviralen eigenschaften

Publications (4)

Publication Number Publication Date
NO20055649D0 NO20055649D0 (no) 2005-11-30
NO20055649L NO20055649L (no) 2006-01-31
NO333265B1 NO333265B1 (no) 2013-04-22
NO333265B3 true NO333265B3 (no) 2019-06-03

Family

ID=33305099

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20055649A NO333265B3 (no) 2003-05-02 2005-11-30 Substituerte dihydrokinazoliner, fremgangsmåte for fremstilling derav, anvendelse av en slik forbindelse samt medikament inneholdende denne.
NO2018022C NO2018022I1 (no) 2003-05-02 2018-07-04 Letermovir, eller dets salt, solvat eller solvat av dets salt

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO2018022C NO2018022I1 (no) 2003-05-02 2018-07-04 Letermovir, eller dets salt, solvat eller solvat av dets salt

Country Status (39)

Country Link
US (4) US7196086B2 (no)
EP (1) EP1622880B3 (no)
JP (1) JP4733631B2 (no)
KR (1) KR100927063B1 (no)
CN (1) CN100393706C (no)
AR (1) AR044078A1 (no)
AT (1) ATE355280T1 (no)
AU (1) AU2004233978B2 (no)
BR (1) BRPI0410029B8 (no)
CA (1) CA2524069C (no)
CL (1) CL2004000930A1 (no)
CO (1) CO5700764A2 (no)
CY (2) CY1106476T1 (no)
DE (2) DE10319612A1 (no)
DK (1) DK1622880T6 (no)
EC (1) ECSP056138A (no)
EG (1) EG25273A (no)
ES (1) ES2284007T7 (no)
FR (1) FR18C1029I2 (no)
HK (1) HK1092463A1 (no)
HN (1) HN2004000146A (no)
HU (2) HUS1800018I1 (no)
IL (1) IL171513A (no)
MA (1) MA27794A1 (no)
MX (1) MXPA05011707A (no)
MY (1) MY144616A (no)
NL (1) NL300933I2 (no)
NO (2) NO333265B3 (no)
NZ (1) NZ543317A (no)
PE (1) PE20050145A1 (no)
PL (1) PL1622880T6 (no)
PT (1) PT1622880E (no)
RU (1) RU2360912C2 (no)
SI (1) SI1622880T1 (no)
TW (1) TWI335912B (no)
UA (1) UA82519C2 (no)
UY (1) UY28294A1 (no)
WO (1) WO2004096778A1 (no)
ZA (1) ZA200508710B (no)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10319612A1 (de) 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
DE10305785A1 (de) * 2003-02-12 2004-08-26 Bayer Healthcare Ag Dihydrochinazoline
DE10320780A1 (de) * 2003-05-09 2005-01-20 Bayer Healthcare Ag Heterocyclyl-substituierte Dihydrochinazoline
DE10352499A1 (de) * 2003-11-11 2005-06-09 Bayer Healthcare Ag Substituierte Dihydrochinazoline II
DE102004022672A1 (de) 2004-05-07 2005-11-24 Bayer Healthcare Ag Substituierte Azachinazoline
DE102005027517A1 (de) * 2005-06-15 2006-12-21 Bayer Healthcare Ag Verfahren zur Herstellung von Dihydrochinazolinen
DE102011101446A1 (de) * 2011-05-10 2012-11-15 Aicuris Gmbh & Co. Kg Herstellung von "Dense Bodies" (DB)
DE102012101659A1 (de) * 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Salze eines Dihydrochinazolinderivats
DE102012101680A1 (de) * 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Pharmazeutische Zubereitung enthaltend ein antiviral wirksames Dihydrochinazolinderivat
DE102012101673A1 (de) 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Salze eines Dihydrochinazolinderivats
EP3010891B1 (en) * 2013-06-19 2019-04-10 AiCuris Anti-infective Cures GmbH Amorphous letermovir and solid pharmaceutical formulations thereof for oral administration
US9890128B2 (en) 2013-12-12 2018-02-13 Merck Sharp & Dohme Corp. Process for making substituted quinazoline compounds
US10392353B2 (en) * 2015-11-24 2019-08-27 Merck Sharp & Dohme Corp. Processes for making substituted quinazoline compounds using hydrogen bonding catalysts
WO2018028556A1 (zh) * 2016-08-08 2018-02-15 南京明德新药研发股份有限公司 抗hcmv病毒化合物
US11174270B2 (en) 2018-02-08 2021-11-16 Phaeno Therapeutics Co., Ltd. Crystal form of 3,4-dihydrothieno[3,2-d]pyrimidine compound and preparation method thereof
EP3527209A1 (en) * 2018-02-16 2019-08-21 UCB Biopharma SPRL Pharmaceutical 6,5 heterobicyclic ring derivatives
AU2019339777B2 (en) 2018-09-12 2022-09-01 Novartis Ag Antiviral pyridopyrazinedione compounds
KR20220070005A (ko) 2019-09-26 2022-05-27 노파르티스 아게 항바이러스성 피라졸로피리디논 화합물
UY39096A (es) 2020-02-27 2021-09-30 Aic246 Gmbh & Co Kg Un método para producir una forma cristalina de 2-[(4s)-8- fluoro-2-[4-(3-metoxifenil)piperazin-1-il]-3-[2-metoxi-5- (trifluorometil)fenil]-4h-quinazolin-4-il]acetato de sodio trihidrato
UY39098A (es) * 2020-02-27 2021-09-30 Aic246 Gmbh & Co Kg 2-[(4s)-8-fluoro-2-[4-(3-metoxifenil)piperazin-1-il]-3-[2-metoxi-5- (trifluorometil)fenil]-4h-quinazolin-4-il] acetato de sodio monohidrato, su preparación y uso
AR121438A1 (es) 2020-02-27 2022-06-08 Aic246 Gmbh & Co Kg Composiciones farmacéuticas que comprenden acetato de 2-[(4s)-8-fluoro-2-[4-(3-metoxifenil)piperazin-1-il]-3-[2-metoxi-5-(trifluorometil)fenil]-4h-quinazolin-4-il] e iones de sodio
UY39099A (es) 2020-02-27 2021-08-31 Aic246 Gmbh & Co Kg 2-[(4s)-8-fluoro-2-[4-(3-metoxifenil)piperazin-1-il]-3-[2-metoxi-5-(trifluorometil)fenil]-4h-quinazolin-4-il] acetato de sodio y composiciones farmacéuticas del mismo
AR121437A1 (es) 2020-02-27 2022-06-08 Aic246 Gmbh & Co Kg Sal de potasio del ácido 2-[(4s)-8-fluoro-2-[4-(3-metoxifenil)piperazin-1-il]-3-[2-metoxi-5-(trifluorometil)fenil]-4h-quinazolin-4-il]acético
EP3906929A1 (en) 2020-05-08 2021-11-10 AiCuris GmbH & Co. KG Letermovir for use in the prevention and the treatment of coronavirus infections
CA3189271A1 (en) 2020-08-17 2022-02-24 Girij Pal Singh A precipitation process for amorphous letermovir
CN115403528A (zh) * 2021-05-27 2022-11-29 南京正大天晴制药有限公司 无定形3,4-二氢喹唑啉衍生物的制备方法
CN114031560B (zh) * 2021-11-16 2022-10-04 山东诚创蓝海医药科技有限公司 一种来特莫韦钠盐的制备方法
AR128035A1 (es) 2021-12-21 2024-03-20 Aic246 Ag & Co Kg Composiciones farmacéuticas que comprenden acetato de 2-[(4s)-8-fluoro-2-[4-(3-metoxifenil)piperazin-1-il]-3-[2-metoxi-5-(trifluorometil)fenil]-4h-quinazolin-4-il] e iones de potasio
WO2023185597A1 (zh) * 2022-04-01 2023-10-05 上海迪赛诺化学制药有限公司 莱特莫韦中间体及其制备方法
CN115322157B (zh) * 2022-06-02 2023-12-05 浙江车头制药股份有限公司 来特莫韦中间体化合物及其制备方法和应用
CN117229223A (zh) * 2022-06-08 2023-12-15 苏州远智医药科技有限公司 一种杂环衍生物及其药物组合物、应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1201765A2 (en) * 2000-10-16 2002-05-02 Axxima Pharmaceuticals Aktiengesellschaft Cellular kinases involved in cytomegalovirus infection and their inhibition

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4320347A1 (de) 1993-06-19 1994-12-22 Boehringer Mannheim Gmbh Quinazolin-Derivate und diese enthaltende Arzneimittel
US5854245A (en) * 1996-06-28 1998-12-29 Merck & Co., Inc. Fibrinogen receptor antagonists
DE19802437A1 (de) 1998-01-23 1999-07-29 Bayer Ag Verwendung von substituierten Sulfonamiden als anitvirale Mittel und neue Stoffe
KR20010041015A (ko) 1998-02-17 2001-05-15 윌리엄 제이. 리플린 항바이러스성 피리미딘 유도체
KR20010113820A (ko) 1999-04-19 2001-12-28 시오노 요시히코 옥사디아졸 고리를 갖는 술폰아미드 유도체
DE19930075A1 (de) 1999-06-30 2001-01-04 Bayer Ag Neue Amino- und Amidosulfonamide als antivirale Mittel
US6730682B2 (en) * 2000-07-12 2004-05-04 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
KR100539139B1 (ko) * 2000-07-31 2005-12-26 에프. 호프만-라 로슈 아게 피페라진 유도체
EE200300515A (et) 2001-04-19 2004-02-16 Bayer Aktiengeshellschaft Arüülsulfoonamiidid kui viirusevastased ained
DE10138578A1 (de) 2001-08-06 2003-02-27 Bayer Ag Heterocyclylarylsulfonamide
DE10251914A1 (de) 2002-11-08 2004-05-19 Bayer Ag Substituierte Chinazoline
DE10319612A1 (de) 2003-05-02 2004-11-18 Bayer Healthcare Ag Substituierte Dihydrochinazoline
DE10305785A1 (de) * 2003-02-12 2004-08-26 Bayer Healthcare Ag Dihydrochinazoline
DE10320780A1 (de) * 2003-05-09 2005-01-20 Bayer Healthcare Ag Heterocyclyl-substituierte Dihydrochinazoline
DE10352499A1 (de) * 2003-11-11 2005-06-09 Bayer Healthcare Ag Substituierte Dihydrochinazoline II
KR100610731B1 (ko) 2004-02-24 2006-08-09 한국과학기술연구원 T-형 칼슘 채널 차단제로서 유용한 3,4-디히드로퀴나졸린유도체 및 그의 제조 방법
DE102004022672A1 (de) * 2004-05-07 2005-11-24 Bayer Healthcare Ag Substituierte Azachinazoline
JP5139083B2 (ja) * 2005-01-25 2013-02-06 プロレキシーズ ファーマシューティカルズ インコーポレイテッド 抗腫瘍剤としてのキノキサリン誘導体
DE102005027517A1 (de) 2005-06-15 2006-12-21 Bayer Healthcare Ag Verfahren zur Herstellung von Dihydrochinazolinen
KR100962723B1 (ko) * 2005-07-21 2010-06-09 에프. 호프만-라 로슈 아게 단백질 티로신 포스파타제1b 억제제로서의피리도[2,3-d]피리미딘-2,4-다이아민 화합물
DE102006009928A1 (de) 2006-03-03 2007-09-06 Aicuris Gmbh & Co. Kg Substituierte Arylsulfonamide
DE102012101673A1 (de) 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Salze eines Dihydrochinazolinderivats
DE102012101680A1 (de) * 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Pharmazeutische Zubereitung enthaltend ein antiviral wirksames Dihydrochinazolinderivat
DE102012101659A1 (de) * 2012-02-29 2013-08-29 Aicuris Gmbh & Co. Kg Salze eines Dihydrochinazolinderivats
EP3010891B1 (en) * 2013-06-19 2019-04-10 AiCuris Anti-infective Cures GmbH Amorphous letermovir and solid pharmaceutical formulations thereof for oral administration

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1201765A2 (en) * 2000-10-16 2002-05-02 Axxima Pharmaceuticals Aktiengesellschaft Cellular kinases involved in cytomegalovirus infection and their inhibition

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MARINEZ, A. ET AL.Benzothiadiazine dioxide human cytomegalovirus inhibitors: synthesis and antiviral evaluation of main heterocycle modified derivatives.Antiviral Chemistry & Chemotherapy. 2003, 14(2) s. 107-114., Dated: 01.01.0001 *

Also Published As

Publication number Publication date
EP1622880B1 (de) 2007-02-28
ES2284007T7 (es) 2018-06-20
NZ543317A (en) 2008-05-30
CN100393706C (zh) 2008-06-11
CY1106476T1 (el) 2012-01-25
NO20055649L (no) 2006-01-31
MY144616A (en) 2011-10-14
HUS1800028I1 (hu) 2018-07-30
DK1622880T3 (da) 2007-06-25
HN2004000146A (es) 2008-06-24
JP4733631B2 (ja) 2011-07-27
NO2018022I1 (no) 2018-07-04
MXPA05011707A (es) 2006-02-13
CY2018019I1 (el) 2018-12-12
PT1622880E (pt) 2007-06-04
ECSP056138A (es) 2006-04-19
HK1092463A1 (en) 2007-02-09
AU2004233978A1 (en) 2004-11-11
RU2360912C2 (ru) 2009-07-10
ZA200508710B (en) 2006-12-27
UA82519C2 (uk) 2008-04-25
JP2006525249A (ja) 2006-11-09
CL2004000930A1 (es) 2005-03-18
CY2018019I2 (el) 2018-12-12
MA27794A1 (fr) 2006-03-01
KR100927063B1 (ko) 2009-11-13
NL300933I2 (nl) 2018-04-26
EG25273A (en) 2011-12-04
USRE49698E1 (en) 2023-10-17
CN1784390A (zh) 2006-06-07
RU2005137276A (ru) 2006-07-27
FR18C1029I1 (no) 2018-08-17
EP1622880A1 (de) 2006-02-08
USRE46791E1 (en) 2018-04-17
AR044078A1 (es) 2005-08-24
PL1622880T3 (pl) 2007-08-31
BRPI0410029A (pt) 2006-04-25
US20070191387A1 (en) 2007-08-16
UY28294A1 (es) 2004-11-30
NO20055649D0 (no) 2005-11-30
KR20060009883A (ko) 2006-02-01
ATE355280T1 (de) 2006-03-15
FR18C1029I2 (fr) 2020-07-17
CA2524069A1 (en) 2004-11-11
US7196086B2 (en) 2007-03-27
ES2284007T3 (es) 2007-11-01
TWI335912B (en) 2011-01-11
NO333265B1 (no) 2013-04-22
US8513255B2 (en) 2013-08-20
TW200510343A (en) 2005-03-16
BRPI0410029B8 (pt) 2021-06-15
PE20050145A1 (es) 2005-05-22
DE502004003052D1 (de) 2007-04-12
SI1622880T1 (sl) 2007-08-31
US20050065160A1 (en) 2005-03-24
DK1622880T6 (da) 2018-06-18
EP1622880B3 (de) 2018-05-23
AU2004233978B2 (en) 2010-02-11
CO5700764A2 (es) 2006-11-30
WO2004096778A1 (de) 2004-11-11
BRPI0410029B1 (pt) 2019-12-31
CA2524069C (en) 2011-11-08
IL171513A (en) 2011-11-30
HUS1800018I1 (hu) 2018-05-28
DE10319612A1 (de) 2004-11-18
PL1622880T6 (pl) 2018-08-31

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