NO302521B1 - Fremgangsmåte for fremstilling av derivater av baccatin-III og 10-desacetyl-baccatin-III - Google Patents

Fremgangsmåte for fremstilling av derivater av baccatin-III og 10-desacetyl-baccatin-III

Info

Publication number
NO302521B1
NO302521B1 NO934485A NO934485A NO302521B1 NO 302521 B1 NO302521 B1 NO 302521B1 NO 934485 A NO934485 A NO 934485A NO 934485 A NO934485 A NO 934485A NO 302521 B1 NO302521 B1 NO 302521B1
Authority
NO
Norway
Prior art keywords
baccatin
iii
preparation
derivatives
general formula
Prior art date
Application number
NO934485A
Other languages
English (en)
Other versions
NO934485L (no
Inventor
Augustin Hittinger
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO934485L publication Critical patent/NO934485L/no
Publication of NO302521B1 publication Critical patent/NO302521B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
NO934485A 1991-07-10 1993-12-08 Fremgangsmåte for fremstilling av derivater av baccatin-III og 10-desacetyl-baccatin-III NO302521B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9108673A FR2678930B1 (fr) 1991-07-10 1991-07-10 Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
PCT/FR1992/000649 WO1993001179A1 (fr) 1991-07-10 1992-07-08 Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii

Publications (2)

Publication Number Publication Date
NO934485L NO934485L (no) 1993-12-08
NO302521B1 true NO302521B1 (no) 1998-03-16

Family

ID=9414931

Family Applications (2)

Application Number Title Priority Date Filing Date
NO934485A NO302521B1 (no) 1991-07-10 1993-12-08 Fremgangsmåte for fremstilling av derivater av baccatin-III og 10-desacetyl-baccatin-III
NO934485D NO934485D0 (no) 1991-07-10 1993-12-08 Fremgangsmaate for fremstilling av derivater av baccatin-III og 10-des-acetyl-baccati n-III

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO934485D NO934485D0 (no) 1991-07-10 1993-12-08 Fremgangsmaate for fremstilling av derivater av baccatin-III og 10-des-acetyl-baccati n-III

Country Status (25)

Country Link
US (1) US5578739A (no)
EP (2) EP0522958A1 (no)
JP (1) JP3085710B2 (no)
KR (1) KR100206458B1 (no)
AT (1) ATE132145T1 (no)
AU (1) AU662346B2 (no)
CA (1) CA2111319C (no)
CZ (1) CZ281288B6 (no)
DE (1) DE69207194T2 (no)
DK (1) DK0593641T3 (no)
ES (1) ES2081120T3 (no)
FI (1) FI109792B (no)
FR (1) FR2678930B1 (no)
GR (1) GR3018543T3 (no)
HU (1) HU217115B (no)
IE (1) IE73637B1 (no)
MX (1) MX9204029A (no)
NO (2) NO302521B1 (no)
NZ (1) NZ243491A (no)
PL (1) PL169780B1 (no)
RU (1) RU2088578C1 (no)
SK (1) SK281560B6 (no)
WO (1) WO1993001179A1 (no)
YU (1) YU49175B (no)
ZA (1) ZA925098B (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
US5294637A (en) * 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
US5380751A (en) * 1992-12-04 1995-01-10 Bristol-Myers Squibb Company 6,7-modified paclitaxels
CA2111527C (en) * 1992-12-24 2000-07-18 Jerzy Golik Phosphonooxymethyl ethers of taxane derivatives
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
FR2703049B1 (fr) * 1993-03-22 1995-04-21 Rhone Poulenc Rorer Sa Procédé de purification des taxoïdes.
CA2129288C (en) * 1993-08-17 2000-05-16 Jerzy Golik Phosphonooxymethyl esters of taxane derivatives
FR2718135B1 (fr) * 1994-04-05 1996-04-26 Rhone Poulenc Rorer Sa Procédé de préparation d'hydroxy-7 taxanes.
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) * 1995-09-12 2000-04-18 Mayhew; Eric Liposomal hydrolysis-promoting hydrophobic taxane derivatives
FR2740451B1 (fr) 1995-10-27 1998-01-16 Seripharm Nouveaux intermediaires pour l'hemisynthese de taxanes, leurs procedes de preparation et leur utilisation dans la synthese generale des taxanes
FR2742751B1 (fr) * 1995-12-22 1998-01-30 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
CN1150149C (zh) 1997-08-21 2004-05-19 佛罗里达州立大学 紫杉烷类化合物的合成方法
US5917062A (en) * 1997-11-21 1999-06-29 Indena S.P.A Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
DK1068192T3 (da) * 1998-01-14 2002-10-14 Bristol Myers Squibb Co Hidtil ukendte krystallinske komplekser af baccatin III med imidazol, 2-methylimidazol eller isopropanol
IL139316A0 (en) * 1998-05-01 2001-11-25 Napro Biotherapeutics Inc Methods and intermediate compounds for preparing paclitaxel
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
IT1319168B1 (it) * 2000-03-17 2003-09-26 Indena Spa Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono.
EP2389946A1 (en) 2006-03-23 2011-11-30 Novartis AG Anti-tumor cell antigen antibody therapeutics
DE102008013929B3 (de) * 2008-03-12 2009-04-09 Wieland-Werke Ag Verdampferrohr mit optimierten Hinterschneidungen am Nutengrund
CN101531645B (zh) * 2009-04-29 2012-08-22 深圳万乐药业有限公司 一种多西他赛的合成方法
CN104582732A (zh) 2012-06-15 2015-04-29 布里格姆及妇女医院股份有限公司 治疗癌症的组合物及其制造方法
AU2015241198A1 (en) 2014-04-03 2016-11-17 Invictus Oncology Pvt. Ltd. Supramolecular combinatorial therapeutics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol

Also Published As

Publication number Publication date
FI940075A (fi) 1994-01-07
PL169780B1 (pl) 1996-08-30
EP0593641A1 (fr) 1994-04-27
NO934485D0 (no) 1993-12-08
WO1993001179A1 (fr) 1993-01-21
ES2081120T3 (es) 1996-02-16
DK0593641T3 (da) 1996-01-29
CZ281288B6 (cs) 1996-08-14
NO934485L (no) 1993-12-08
US5578739A (en) 1996-11-26
RU2088578C1 (ru) 1997-08-27
JPH06509082A (ja) 1994-10-13
FR2678930A1 (fr) 1993-01-15
ATE132145T1 (de) 1996-01-15
YU49175B (sh) 2004-07-15
KR100206458B1 (ko) 1999-07-01
IE73637B1 (en) 1997-06-18
CA2111319A1 (fr) 1993-01-21
NZ243491A (en) 1995-05-26
FR2678930B1 (fr) 1995-01-13
ZA925098B (en) 1993-04-28
SK1794A3 (en) 1994-11-09
HU217115B (hu) 1999-11-29
JP3085710B2 (ja) 2000-09-11
DE69207194D1 (de) 1996-02-08
GR3018543T3 (en) 1996-03-31
EP0522958A1 (fr) 1993-01-13
DE69207194T2 (de) 1996-09-05
FI940075A0 (fi) 1994-01-07
IE922234A1 (en) 1993-01-13
CZ3194A3 (en) 1994-04-13
AU662346B2 (en) 1995-08-31
YU68792A (sh) 1995-10-03
HU9400062D0 (en) 1994-05-30
SK281560B6 (sk) 2001-05-10
HUT66018A (en) 1994-08-29
AU2328092A (en) 1993-02-11
EP0593641B1 (fr) 1995-12-27
FI109792B (fi) 2002-10-15
CA2111319C (fr) 2003-04-08
MX9204029A (es) 1993-01-01

Similar Documents

Publication Publication Date Title
NO302521B1 (no) Fremgangsmåte for fremstilling av derivater av baccatin-III og 10-desacetyl-baccatin-III
MY119150A (en) Azetidine derivatives, their preparation and medicaments containing them
ATE338744T1 (de) Hydrazonderivate
RU94016161A (ru) Способ получения производных iii или 10-дезацетилбаккатина iii и их применение
HU9201288D0 (en) Kinoxalyne derivatives, process for their production and medical preparations containing them
FI932992A0 (fi) Fungisida fenylbenzamider och foerfaranden foer framstaellning daerav
FI881609A (fi) Dihydropyridinamider, foerfarande foer deras framstaellning och deras anvaendning i laekemedel.
FI944190A0 (fi) Menetelmä taksaanijohdannaisten valmistamiseksi
DK0623620T3 (da) 5-HT3-pyrrolopyrazinderivater
ATE170520T1 (de) Eburnan-derivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
NO932418L (no) Pyrimidinderivater, fremgangsmaate for deres fremstilling og terapeutiske anvendelse derav
ES2098517T3 (es) Derivados de 1,2,4-tiadiazino(3,4-b)benzotiazol, su preparacion y los medicamentos que los contienen.
ZA924888B (en) Process for the synthesis of enantiomers of 3-aminochroman compounds
SE9203824L (sv) Bensofuranylimidazol-derivat, foerfarande foer framstaellning daerav och terapeutiska kompositioner innehaallande desamma
DK0552631T3 (da) Alfa-Aryl-alfa-hydroxy-beta-imidazolinyl-propionsyreamider
ATE125790T1 (de) N-fumaramidsäurederivate und diese enthaltende fungizide.
ATE53839T1 (de) 2,3-dihydro-3-phenyl-benzofuran-2-onacetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
DE69407042D1 (de) Psoralen-derivate, deren herstellung und verwendung als arzneimittel

Legal Events

Date Code Title Description
MK1K Patent expired