NO301168B1 - Fremgangsmåte for fremstilling av et konjugat av et antistoff rettet mot antigen - Google Patents

Fremgangsmåte for fremstilling av et konjugat av et antistoff rettet mot antigen Download PDF

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Publication number
NO301168B1
NO301168B1 NO901986A NO901986A NO301168B1 NO 301168 B1 NO301168 B1 NO 301168B1 NO 901986 A NO901986 A NO 901986A NO 901986 A NO901986 A NO 901986A NO 301168 B1 NO301168 B1 NO 301168B1
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NO
Norway
Prior art keywords
tnf
cells
antibody
antigen
tumor
Prior art date
Application number
NO901986A
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English (en)
Norwegian (no)
Other versions
NO901986L (no
NO901986D0 (no
Inventor
Michael G Rosenblum
Clyde William Wellen
Original Assignee
Res Dev Foundation
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Filing date
Publication date
Application filed by Res Dev Foundation filed Critical Res Dev Foundation
Publication of NO901986D0 publication Critical patent/NO901986D0/no
Publication of NO901986L publication Critical patent/NO901986L/no
Publication of NO301168B1 publication Critical patent/NO301168B1/no

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Materials For Medical Uses (AREA)
NO901986A 1989-05-05 1990-05-04 Fremgangsmåte for fremstilling av et konjugat av et antistoff rettet mot antigen NO301168B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34823789A 1989-05-05 1989-05-05

Publications (3)

Publication Number Publication Date
NO901986D0 NO901986D0 (no) 1990-05-04
NO901986L NO901986L (no) 1990-11-06
NO301168B1 true NO301168B1 (no) 1997-09-22

Family

ID=23367161

Family Applications (1)

Application Number Title Priority Date Filing Date
NO901986A NO301168B1 (no) 1989-05-05 1990-05-04 Fremgangsmåte for fremstilling av et konjugat av et antistoff rettet mot antigen

Country Status (19)

Country Link
EP (1) EP0396387B1 (ja)
JP (1) JP3589459B2 (ja)
KR (1) KR0181294B1 (ja)
CN (1) CN1072505C (ja)
AT (1) ATE98873T1 (ja)
AU (1) AU645747B2 (ja)
CA (1) CA2015060C (ja)
DE (1) DE69005352T2 (ja)
DK (1) DK0396387T3 (ja)
ES (1) ES2060947T3 (ja)
FI (1) FI100092B (ja)
HK (1) HK1006678A1 (ja)
IE (1) IE63847B1 (ja)
IL (1) IL94167A (ja)
NO (1) NO301168B1 (ja)
NZ (1) NZ233413A (ja)
PT (1) PT93966B (ja)
SA (1) SA90110099B1 (ja)
ZA (1) ZA902949B (ja)

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