NO2015005I1 - Flutemetamol (18F) - Google Patents

Flutemetamol (18F)

Info

Publication number
NO2015005I1
NO2015005I1 NO2015005C NO2015005C NO2015005I1 NO 2015005 I1 NO2015005 I1 NO 2015005I1 NO 2015005 C NO2015005 C NO 2015005C NO 2015005 C NO2015005 C NO 2015005C NO 2015005 I1 NO2015005 I1 NO 2015005I1
Authority
NO
Norway
Prior art keywords
fluoromethamol
Prior art date
Application number
NO2015005C
Other languages
English (en)
Other versions
NO2015005I2 (no
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/388,173 external-priority patent/US7270800B2/en
Priority claimed from US10/645,847 external-priority patent/US20050043523A1/en
Priority claimed from PCT/US2004/007797 external-priority patent/WO2004083195A1/en
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Publication of NO2015005I2 publication Critical patent/NO2015005I2/no
Publication of NO2015005I1 publication Critical patent/NO2015005I1/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
NO2015005C 2003-03-14 2015-02-18 Flutemetamol (18F) NO2015005I1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/388,173 US7270800B2 (en) 2000-08-24 2003-03-14 Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US10/645,847 US20050043523A1 (en) 2003-08-22 2003-08-22 Benzothiazole derivative compounds, compositions and uses
PCT/US2004/007797 WO2004083195A1 (en) 2003-03-14 2004-03-15 Benzothiazole derivative compounds, compositions and uses

Publications (2)

Publication Number Publication Date
NO2015005I2 NO2015005I2 (no) 2015-02-18
NO2015005I1 true NO2015005I1 (no) 2015-03-02

Family

ID=35057877

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20054674A NO330861B1 (no) 2003-03-14 2005-10-11 Benzotiazolavledede forbindelser, preparater og anvendelser
NO20110980A NO20110980L (no) 2003-03-14 2011-07-06 Benzotiazolavledede forbindelser, preparater og anvendelser
NO2015005C NO2015005I1 (no) 2003-03-14 2015-02-18 Flutemetamol (18F)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO20054674A NO330861B1 (no) 2003-03-14 2005-10-11 Benzotiazolavledede forbindelser, preparater og anvendelser
NO20110980A NO20110980L (no) 2003-03-14 2011-07-06 Benzotiazolavledede forbindelser, preparater og anvendelser

Country Status (16)

Country Link
EP (1) EP1611115B1 (no)
JP (1) JP4875487B2 (no)
CN (2) CN1784392A (no)
AU (2) AU2004221897B2 (no)
BE (1) BE2015C005I2 (no)
BR (1) BRPI0408274B8 (no)
CY (2) CY1113334T1 (no)
DK (1) DK1611115T3 (no)
ES (1) ES2393921T3 (no)
HK (1) HK1086270A1 (no)
HU (1) HUS1500006I1 (no)
NO (3) NO330861B1 (no)
PL (1) PL1611115T3 (no)
PT (1) PT1611115E (no)
RU (1) RU2440995C2 (no)
SI (1) SI1611115T1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1334091T3 (da) * 2000-08-24 2012-10-15 Univ Pittsburgh Thioflavinderivater og deres anvendelse til diagnose og terapi af Alzheimer's sygdom
US7270800B2 (en) 2000-08-24 2007-09-18 University Of Pittsburgh Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
JP2007538103A (ja) * 2004-05-20 2007-12-27 ザ スクリップス リサーチ インスティテュート トランスサイレチン安定化
GB0516564D0 (en) * 2005-08-12 2005-09-21 Ge Healthcare Ltd Fluorination process
WO2008093057A1 (en) * 2007-01-30 2008-08-07 Ge Healthcare Limited Tools for aiding in the diagnosis of neurodegenerative diseases
CN101293878B (zh) * 2007-04-25 2010-12-15 中国科学院上海应用物理研究所 苯并噻唑苯胺类化合物及其制备方法和应用
EP2323697A2 (en) * 2008-07-24 2011-05-25 Siemens Medical Solutions USA, Inc. Imaging agents useful for identifying ad pathology
AU2009295701B2 (en) * 2008-09-23 2014-07-24 Wista Laboratories Ltd. Ligands for aggregated tau molecules
JP6182668B2 (ja) 2013-09-26 2017-08-16 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 画像化ツールとしてのイミダゾ［１，２−ａ］ピリジン−７−アミン
JP6260967B2 (ja) * 2013-11-06 2018-01-17 国立大学法人京都大学 放射性ヨウ素標識化合物、及び、これを含む放射性医薬
CN103613589B (zh) * 2013-11-29 2016-03-30 江苏华益科技有限公司 一种用于神经退行性疾病领域的新型pet显像剂前体及标准品的合成方法
AU2015308709B2 (en) * 2014-08-29 2020-01-02 Chdi Foundation, Inc. Probes for imaging huntingtin protein
CN109400615B (zh) * 2017-08-18 2021-07-16 上海交通大学医学院附属新华医院 一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用
GR1009516B (el) * 2018-03-22 2019-05-02 Εκεφε Δημοκριτος Τρικαρβονυλο-συμπλοκα μεταλλων μεταπτωσεως με βενζο-ετεροκυκλικο παραγωγο του κυκλοπενταδιενυλικου ανιοντος με υψηλη διαπερατοτητα του αιματοεγκεφαλικου φραγμου για εφαρμογες στη διαγνωση και θεραπεια νοσων του κνς

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID22275A (id) * 1996-11-22 1999-09-23 Elan Pharm Inc Komposisi farmasi yang terdiri dari derivat asam amino n-(aril atau heteroaril) dan metode untuk menghambat pelepasan b-amiloid peptida dan atau sintesisnya dengan menggunakan senyawa tersebut
GB9919673D0 (en) * 1999-08-20 1999-10-20 Cancer Res Campaign Tech 2-Arlybenzazole compounds
DK1334091T3 (da) * 2000-08-24 2012-10-15 Univ Pittsburgh Thioflavinderivater og deres anvendelse til diagnose og terapi af Alzheimer's sygdom
JP2004524289A (ja) * 2000-12-22 2004-08-12 アストラゼネカ・アクチエボラーグ 治療化合物
ES2274973T3 (es) * 2001-04-23 2007-06-01 The Trustees Of The University Of Pennsylvania Inhibidores de la agregacion de placas amiloides y agentes de obtencion de imagenes diagnosticas.
GB0229686D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase fluorination of benzothiazoles

Also Published As

Publication number Publication date
RU2440995C2 (ru) 2012-01-27
NO20110980L (no) 2005-12-13
EP1611115A1 (en) 2006-01-04
AU2011200667B2 (en) 2011-12-22
RU2005131872A (ru) 2006-02-27
AU2004221897A9 (en) 2009-08-20
NO20054674D0 (no) 2005-10-11
BRPI0408274A (pt) 2006-03-21
CY1113334T1 (el) 2015-12-09
AU2011200667A1 (en) 2011-03-10
AU2004221897A1 (en) 2004-09-30
CY2015007I1 (el) 2015-12-09
PT1611115E (pt) 2012-12-07
BRPI0408274B1 (pt) 2019-02-26
DK1611115T3 (da) 2012-11-26
BE2015C005I2 (no) 2023-03-07
NO2015005I2 (no) 2015-02-18
AU2004221897B2 (en) 2010-11-18
ES2393921T3 (es) 2013-01-02
CN1784392A (zh) 2006-06-07
SI1611115T1 (sl) 2012-12-31
JP2006522104A (ja) 2006-09-28
HUS1500006I1 (hu) 2015-02-18
CN102532055B (zh) 2016-05-11
PL1611115T3 (pl) 2013-01-31
NO330861B1 (no) 2011-08-01
HK1086270A1 (en) 2006-09-15
AU2004221897A2 (en) 2004-09-30
CN102532055A (zh) 2012-07-04
NO20054674L (no) 2005-12-13
BRPI0408274B8 (pt) 2021-05-25
JP4875487B2 (ja) 2012-02-15
EP1611115B1 (en) 2012-08-22

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