NO20084674L - 1- [ (4-(benzoyl (metyl) amino] -3- (fenyl) butyl] azetidinderivater for behandling av gastrointestinale lidelser - Google Patents

1- [ (4-(benzoyl (metyl) amino] -3- (fenyl) butyl] azetidinderivater for behandling av gastrointestinale lidelser

Info

Publication number: NO20084674L
Authority: NO; Norway
Prior art keywords: treatment; gastrointestinal disorders; benzoyl; phenyl; butyl
Prior art date: 2006-05-18

Application number

NO20084674A

Other languages

English (en)

Norwegian (no)

Inventor

Carl-Gustaf Sigfridsson

Anders Johansson

Johan Johansson

Original Assignee

Albireo Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-05-18

Filing date

2008-11-06

Publication date

2009-01-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38723558&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20084674(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-11-06 Application filed by Albireo Ab filed Critical Albireo Ab

2009-01-29 Publication of NO20084674L publication Critical patent/NO20084674L/no

Links

208000018522 Gastrointestinal disease Diseases 0.000 title abstract 2
150000001539 azetidines Chemical class 0.000 title 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 title 1
125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 title 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 title 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 5
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000002464 receptor antagonist Substances 0.000 abstract 1
229940044551 receptor antagonist Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

NO20084674A 2006-05-18 2008-11-06 1- [ (4-(benzoyl (metyl) amino] -3- (fenyl) butyl] azetidinderivater for behandling av gastrointestinale lidelser NO20084674L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US80157706P	2006-05-18	2006-05-18
PCT/SE2007/000482 WO2007136324A1 (en)	2006-05-18	2007-05-16	1- [ (4- [benzoyl (methyl) amino] -3- (phenyl) butyl] azetidine derivatives for the treatment of gastrointestinal disorders 1

Publications (1)

Publication Number	Publication Date
NO20084674L true NO20084674L (no)	2009-01-29

Family

ID=38723558

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20084674A NO20084674L (no)	2006-05-18	2008-11-06	1- [ (4-(benzoyl (metyl) amino] -3- (fenyl) butyl] azetidinderivater for behandling av gastrointestinale lidelser

Country Status (24)

Country	Link
US (1)	US8106208B2 (pl)
EP (1)	EP2024354B1 (pl)
JP (1)	JP5196381B2 (pl)
KR (1)	KR101429779B1 (pl)
CN (1)	CN101472910B (pl)
AR (1)	AR060956A1 (pl)
AT (1)	ATE525355T1 (pl)
AU (1)	AU2007253666B2 (pl)
BR (1)	BRPI0712405A2 (pl)
CA (1)	CA2652443C (pl)
DK (1)	DK2024354T3 (pl)
ES (1)	ES2373335T3 (pl)
HK (1)	HK1121758A1 (pl)
IL (1)	IL195197A (pl)
MX (1)	MX2008014686A (pl)
MY (1)	MY147474A (pl)
NO (1)	NO20084674L (pl)
PL (1)	PL2024354T3 (pl)
PT (1)	PT2024354E (pl)
RU (1)	RU2439067C2 (pl)
TW (1)	TW200813006A (pl)
UY (1)	UY30356A1 (pl)
WO (1)	WO2007136324A1 (pl)
ZA (1)	ZA200809909B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR057828A1 (es) *	2005-09-29	2007-12-19	Astrazeneca Ab	Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
CA2663280A1 (en) *	2006-09-14	2008-03-20	Neuromed Pharmaceuticals Ltd.	Diaryl piperidine compounds as calcium channel blockers
CN101790512A (zh) *	2007-03-08	2010-07-28	阿尔比里奥公司	2-取代-3-苯基丙酸衍生物及其在炎性肠病治疗中的用途
US8691804B2 (en) *	2008-05-08	2014-04-08	Evotec Ag	Azetidines and cyclobutanes as histamine H3 receptor antagonists
JP2013540159A (ja) *	2010-10-22	2013-10-31	ヤンセンファーマシューティカエヌ．ベー．	モノアシルグリセロールリパーゼ阻害剤としてのピペリジン−４−イル−アゼチジンジアミド
JP2014528427A (ja) *	2011-09-30	2014-10-27	ヤンセンファーマシューティカエヌ．ベー．	（１−（４−フルオロフェニル）−１ｈ−インドール−５−イル）−（３−（４−（チアゾール−２−カルボニル）ピペラジン−１−イル）アゼチジン−１−イル）メタノンの結晶性塩酸塩、並びに疼痛及び代謝障害の処置におけるその使用
CN104529833B (zh) *	2014-12-10	2016-04-20	广东东阳光药业有限公司	取代的环丁烷羧酸类化合物及其用途
KR102476938B1 (ko)	2017-12-07	2022-12-13	기초과학연구원	핫전자 기반의 산화물-금속 하이브리드 역촉매

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9310066D0 (en)	1993-05-17	1993-06-30	Zeneca Ltd	Alkyl substituted heterocycles
GB9310713D0 (en)	1993-05-24	1993-07-07	Zeneca Ltd	Aryl substituted heterocycles
GB9317104D0 (en)	1993-08-17	1993-09-29	Zeneca Ltd	Therapeutic heterocycles
GB9322643D0 (en)	1993-11-03	1993-12-22	Zeneca Ltd	Lactam derivatives
GB9325074D0 (en)	1993-12-07	1994-02-02	Zeneca Ltd	Bicyclic heterocycles
TW432061B (en)	1994-08-09	2001-05-01	Pfizer Res & Dev	Lactams
GB9502644D0 (en)	1995-02-10	1995-03-29	Zeneca Ltd	Heterocyclic derivatives
GB9600235D0 (en)	1996-01-05	1996-03-06	Pfizer Ltd	Therapeutic agents
GB9601202D0 (en)	1996-01-22	1996-03-20	Pfizer Ltd	Piperidones
GB9601680D0 (en)	1996-01-27	1996-03-27	Pfizer Ltd	Therapeutic agents
GB9601697D0 (en)	1996-01-27	1996-03-27	Pfizer Ltd	Therapeutic agents
GB9714129D0 (en)	1997-07-04	1997-09-10	Pfizer Ltd	Azetidines
GB9812037D0 (en)	1998-06-04	1998-07-29	Pfizer Ltd	Piperidones
US6365602B1 (en)	1998-07-10	2002-04-02	Astra Zeneca Ab	N-substituted naphthalene carboxamides as neurokinin-receptor antagonists
GB9922519D0 (en)	1998-10-07	1999-11-24	Zeneca Ltd	Compounds
GB9922521D0 (en)	1998-10-07	1999-11-24	Zeneca Ltd	Compounds
GB9924141D0 (en)	1998-10-30	1999-12-15	Zeneca Ltd	Treatment of gastric asthma
GB9826941D0 (en)	1998-12-09	1999-02-03	Zeneca Pharmaceuticals	Compounds
SE0004827D0 (sv)	2000-12-22	2000-12-22	Astrazeneca Ab	Therapeutic compounds
SE0103795D0 (sv)	2001-11-02	2001-11-02	Astrazeneca Ab	Compounds and method for the treatment of överactive bladder
TW200508221A (en) *	2003-06-13	2005-03-01	Astrazeneca Ab	New azetidine compounds
CN101208327A (zh) *	2005-06-23	2008-06-25	阿斯利康(瑞典)有限公司	作为神经激肽受体拮抗剂用于治疗胃肠疾病的新氮杂环丁烷衍生物
CN101203511A (zh) *	2005-06-23	2008-06-18	阿斯利康(瑞典)有限公司	作为神经激肽受体拮抗剂用于治疗胃肠疾病的新氮杂环丁烷衍生物
AR057828A1 (es) *	2005-09-29	2007-12-19	Astrazeneca Ab	Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
AR056087A1 (es) *	2005-09-29	2007-09-19	Astrazeneca Ab	Derivados de azetidina como antagonistas de receptores de neuroquina nk

2007
- 2007-05-11 US US11/747,322 patent/US8106208B2/en not_active Expired - Fee Related
- 2007-05-14 TW TW096117067A patent/TW200813006A/zh unknown
- 2007-05-16 CA CA2652443A patent/CA2652443C/en not_active Expired - Fee Related
- 2007-05-16 PT PT07748146T patent/PT2024354E/pt unknown
- 2007-05-16 BR BRPI0712405-8A patent/BRPI0712405A2/pt not_active IP Right Cessation
- 2007-05-16 CN CN200780022773.8A patent/CN101472910B/zh not_active Expired - Fee Related
- 2007-05-16 EP EP07748146A patent/EP2024354B1/en not_active Not-in-force
- 2007-05-16 RU RU2008149927/04A patent/RU2439067C2/ru not_active IP Right Cessation
- 2007-05-16 KR KR1020087029057A patent/KR101429779B1/ko not_active IP Right Cessation
- 2007-05-16 WO PCT/SE2007/000482 patent/WO2007136324A1/en active Application Filing
- 2007-05-16 AU AU2007253666A patent/AU2007253666B2/en not_active Ceased
- 2007-05-16 DK DK07748146.3T patent/DK2024354T3/da active
- 2007-05-16 AT AT07748146T patent/ATE525355T1/de not_active IP Right Cessation
- 2007-05-16 PL PL07748146T patent/PL2024354T3/pl unknown
- 2007-05-16 ES ES07748146T patent/ES2373335T3/es active Active
- 2007-05-16 MX MX2008014686A patent/MX2008014686A/es active IP Right Grant
- 2007-05-16 AR ARP070102113A patent/AR060956A1/es not_active Application Discontinuation
- 2007-05-16 JP JP2009510922A patent/JP5196381B2/ja not_active Expired - Fee Related
- 2007-05-16 UY UY30356A patent/UY30356A1/es unknown
2008
- 2008-11-06 NO NO20084674A patent/NO20084674L/no not_active Application Discontinuation
- 2008-11-10 IL IL195197A patent/IL195197A/en not_active IP Right Cessation
- 2008-11-11 MY MYPI20084521A patent/MY147474A/en unknown
- 2008-11-20 ZA ZA200809909A patent/ZA200809909B/xx unknown
2009
- 2009-02-23 HK HK09101710.8A patent/HK1121758A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU2007253666A1 (en)	2007-11-29
AR060956A1 (es)	2008-07-23
CA2652443C (en)	2014-01-14
CN101472910A (zh)	2009-07-01
IL195197A0 (en)	2009-08-03
AU2007253666B2 (en)	2012-03-15
ES2373335T3 (es)	2012-02-02
PT2024354E (pt)	2011-12-19
US8106208B2 (en)	2012-01-31
DK2024354T3 (da)	2012-01-16
CN101472910B (zh)	2014-03-26
UY30356A1 (es)	2008-01-02
BRPI0712405A2 (pt)	2012-10-16
JP5196381B2 (ja)	2013-05-15
IL195197A (en)	2013-10-31
JP2009537516A (ja)	2009-10-29
MY147474A (en)	2012-12-14
KR20090018926A (ko)	2009-02-24
EP2024354B1 (en)	2011-09-21
US20070270398A1 (en)	2007-11-22
MX2008014686A (es)	2009-02-10
CA2652443A1 (en)	2007-11-29
EP2024354A4 (en)	2009-11-11
KR101429779B1 (ko)	2014-08-19
PL2024354T3 (pl)	2012-02-29
ATE525355T1 (de)	2011-10-15
WO2007136324A1 (en)	2007-11-29
RU2439067C2 (ru)	2012-01-10
TW200813006A (en)	2008-03-16
RU2008149927A (ru)	2010-06-27
EP2024354A1 (en)	2009-02-18
ZA200809909B (en)	2009-08-26
HK1121758A1 (en)	2009-04-30

Legal Events

Date	Code	Title	Description
2017-12-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO20084674L (no)	2009-01-29	1- [ (4-(benzoyl (metyl) amino] -3- (fenyl) butyl] azetidinderivater for behandling av gastrointestinale lidelser
NO20063470L (no)	2006-11-17	Tetrazolforbindelser og deres anvendelse av metabotrofe glutamatreseptorantagonister
NO20063599L (no)	2006-10-27	Ytterligere heterosykliske forbindelser og deres anvendelse som metabotrofiske glutamatreseptorantagonister
NO20063468L (no)	2006-11-15	Triazolforbindelser og deres anvendelse som metabotrofe glutamatreseptorantagonister
NO341591B1 (no)	2017-12-11	3-Z-[1-(4-(N-((4-metyl-piperazin-1-yl)-metylkarbonyl)-N-metyl-amino)-anilino)-1-fenyl-metylen]-6-metoksykarbonyl-2-indolinon, tautomerene, diastereomerene, enantiomerene, blandinger derav og saltene derav, og i kombinasjon med en ytterligere farmakologisk aktiv substans, for anvendelse i forebygging eller behandling av fibrose ved revmatoid artritt
NO20073663L (no)	2007-09-03	Tiazol-4-karboksamid-derivater som mGluR5 antagonister
PE20060748A1 (es)	2006-10-01	Derivados de indolcarboxamida como inhibidores de quinasa ikk2
NO20091590L (no)	2009-05-08	Heterocykliske amidforbindelser anvendbare som kinaseinhibitorer
NO20071140L (no)	2007-04-19	Nye piperidinderivater som histamin H3 reseptorligander for behandling av depresjon
NO20063597L (no)	2006-10-10	Acetylinske piperazinforbindelser og deres anvendelse som metabotrofiske glutamatreseptorantagonister
NO20063469L (no)	2006-11-15	Polyeheterosykliske forbindelser og deres anvendelse som metabotrofe glutamat reseptorantagonister
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NO20084403L (no)	2008-11-14	Cykloheksylpyrazol-lactamderivater som inhibitorer av II-beta-hydroksysteroid dehydrogenase I
NO20071593L (no)	2007-05-22	Pyrimidinderivater
NO20083514L (no)	2008-10-30	Heterobicykliske sulfonamidderivater for behandling av diabetes
NZ594597A (en)	2014-02-28	Substituted piperidines as ccr3 antagonists
NO20080670L (no)	2008-04-01	Substituerte piperaziner som metabotrofiske glutamatreseptorantagonister
NO20084418L (no)	2008-12-23	Azolopyridin-3-on derivater som inhibitorer av endoteliallipase
NO20085068L (no)	2009-02-04	Fenylamino-benzoksazolsubstituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter
NO20055688L (no)	2006-01-09	Organiske forbindelser
NO20076424L (no)	2008-03-18	N-koblete heterocykliske antagonister av P2Y1 reseptoren nyttige for behandling av tromboseforstyrrelser
NO20070336L (no)	2007-02-13	Indolderivater som histamin-reseptorantagonister
NO20080445L (no)	2008-01-23	Nye azetidinderivater som neurokininreseptorantagonister for behandling av gastrointestinale sykdommer