NO20076465L - PIGG YBAC som et verktoy for genetisk manipulasjon og analyser i vertebrater - Google Patents
PIGG YBAC som et verktoy for genetisk manipulasjon og analyser i vertebraterInfo
- Publication number
- NO20076465L NO20076465L NO20076465A NO20076465A NO20076465L NO 20076465 L NO20076465 L NO 20076465L NO 20076465 A NO20076465 A NO 20076465A NO 20076465 A NO20076465 A NO 20076465A NO 20076465 L NO20076465 L NO 20076465L
- Authority
- NO
- Norway
- Prior art keywords
- vertebrates
- ybac
- pigg
- tool
- analysis
- Prior art date
Links
- 241000251539 Vertebrata <Metazoa> Species 0.000 title abstract 2
- 238000012252 genetic analysis Methods 0.000 title 1
- 238000010353 genetic engineering Methods 0.000 title 1
- 230000009261 transgenic effect Effects 0.000 abstract 3
- 241000124008 Mammalia Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/90—Vectors containing a transposable element
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Environmental Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2005/000674 WO2006122442A1 (en) | 2005-05-14 | 2005-05-14 | Piggybac as a tool for genetic manipulation and analysis in vertebrates |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20076465L true NO20076465L (no) | 2008-02-04 |
Family
ID=37430916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20076465A NO20076465L (no) | 2005-05-14 | 2007-12-14 | PIGG YBAC som et verktoy for genetisk manipulasjon og analyser i vertebrater |
Country Status (11)
Country | Link |
---|---|
US (1) | US20100154070A1 (pt) |
EP (1) | EP1896578A4 (pt) |
JP (1) | JP2008545375A (pt) |
CN (1) | CN101297031B (pt) |
AU (1) | AU2005331864A1 (pt) |
BR (1) | BRPI0520212A2 (pt) |
CA (1) | CA2608481A1 (pt) |
IL (1) | IL187348A0 (pt) |
MX (1) | MX2007014139A (pt) |
NO (1) | NO20076465L (pt) |
WO (1) | WO2006122442A1 (pt) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10087463B2 (en) * | 2000-10-31 | 2018-10-02 | University Of Notre Dame Du Lac | Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac |
WO2008027384A1 (en) * | 2006-08-28 | 2008-03-06 | University Of Hawaii | Methods and compositions for transposon-mediated transgenesis |
US8546135B2 (en) | 2007-02-09 | 2013-10-01 | University Of Utah Research Foundation | In vivo genome-wide mutagenesis |
US20090042297A1 (en) * | 2007-06-01 | 2009-02-12 | George Jr Alfred L | Piggybac transposon-based vectors and methods of nucleic acid integration |
WO2009097006A2 (en) * | 2007-08-10 | 2009-08-06 | Medarex, Inc. | Hco32 and hco27 and related examples |
WO2010099296A1 (en) | 2009-02-26 | 2010-09-02 | Transposagen Biopharmaceuticals, Inc. | Hyperactive piggybac transposases |
US9445581B2 (en) | 2012-03-28 | 2016-09-20 | Kymab Limited | Animal models and therapeutic molecules |
EP2792236B2 (en) * | 2009-07-08 | 2023-03-22 | Kymab Limited | Animal models and therapeutic molecules |
CN101851637B (zh) * | 2010-01-15 | 2011-12-14 | 中国农业科学院北京畜牧兽医研究所 | 一种制备同时表达多个基因的转基因动物的方法 |
US9796788B2 (en) | 2010-02-08 | 2017-10-24 | Regeneron Pharmaceuticals, Inc. | Mice expressing a limited immunoglobulin light chain repertoire |
US20130045492A1 (en) | 2010-02-08 | 2013-02-21 | Regeneron Pharmaceuticals, Inc. | Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain |
HUE045591T2 (hu) | 2010-02-08 | 2019-12-30 | Regeneron Pharma | Közönséges könnyûláncú egér |
MY172718A (en) | 2011-08-05 | 2019-12-11 | Regeneron Pharma | Humanized universal light chain mice |
AU2012311288B2 (en) | 2011-09-19 | 2017-08-17 | Kymab Limited | Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics |
EP2761008A1 (en) | 2011-09-26 | 2014-08-06 | Kymab Limited | Chimaeric surrogate light chains (slc) comprising human vpreb |
US9253965B2 (en) | 2012-03-28 | 2016-02-09 | Kymab Limited | Animal models and therapeutic molecules |
GB2502127A (en) | 2012-05-17 | 2013-11-20 | Kymab Ltd | Multivalent antibodies and in vivo methods for their production |
US10251377B2 (en) | 2012-03-28 | 2019-04-09 | Kymab Limited | Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies |
CN102943092B (zh) * | 2012-11-20 | 2014-12-10 | 西北农林科技大学 | 一种通用型PiggyBac转座子转基因载体及其制备方法 |
US9788534B2 (en) | 2013-03-18 | 2017-10-17 | Kymab Limited | Animal models and therapeutic molecules |
US9783618B2 (en) | 2013-05-01 | 2017-10-10 | Kymab Limited | Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics |
US9783593B2 (en) | 2013-05-02 | 2017-10-10 | Kymab Limited | Antibodies, variable domains and chains tailored for human use |
US11707056B2 (en) | 2013-05-02 | 2023-07-25 | Kymab Limited | Animals, repertoires and methods |
WO2014196931A1 (en) * | 2013-06-06 | 2014-12-11 | Agency For Science, Technology And Research | A transposon for genome manipulation |
US9840718B2 (en) | 2013-07-12 | 2017-12-12 | University Of South Alabama | Minimal piggyBac vectors for genome integration |
WO2015049517A2 (en) | 2013-10-01 | 2015-04-09 | Kymab Limited | Animal models and therapeutic molecules |
CA2930315A1 (en) * | 2013-11-18 | 2015-05-21 | Yale University | Compositions and methods of using transposons |
WO2015108993A1 (en) * | 2014-01-14 | 2015-07-23 | Lam Therapeutics, Inc. | Mutagenesis methods |
WO2015143414A2 (en) | 2014-03-21 | 2015-09-24 | Regeneron Pharmaceuticals, Inc. | Non-human animals that make single domain binding proteins |
US20150291975A1 (en) | 2014-04-09 | 2015-10-15 | Dna2.0, Inc. | Enhanced nucleic acid constructs for eukaryotic gene expression |
US10233454B2 (en) | 2014-04-09 | 2019-03-19 | Dna2.0, Inc. | DNA vectors, transposons and transposases for eukaryotic genome modification |
CN107438622A (zh) | 2015-03-19 | 2017-12-05 | 瑞泽恩制药公司 | 选择结合抗原的轻链可变区的非人动物 |
CN106521638A (zh) * | 2015-09-09 | 2017-03-22 | 潘雨堃 | 一种基因突变大鼠资源库及其制备方法 |
CN106544359B (zh) * | 2015-09-22 | 2019-07-19 | 复旦大学 | Gpr45基因的用途 |
ES2891087T3 (es) | 2015-10-08 | 2022-01-26 | Dna Twopointo Inc | Vectores de ADN, trasposones y transposasas para la modificación del genoma eucariota |
MX2018007203A (es) * | 2015-12-14 | 2018-11-12 | Genomefrontier Therapeutics Inc | Sistema de transposon, kit que comprende el mismo, y sus usos. |
EP3433366B1 (en) * | 2016-03-25 | 2022-05-18 | GenomeFrontier Therapeutics, Inc. | Kit for constructing transposon and use thereof |
EP3556855A4 (en) * | 2016-12-14 | 2020-07-15 | Shinshu University | GENE-MODIFIED LYMPHOCYT WITH CHIMERAL ANTIGENT RECEPTOR WITH CELL-DESTRUCTING EFFECT |
JP7203367B2 (ja) * | 2017-12-14 | 2023-01-16 | 公益財団法人実験動物中央研究所 | 哺乳動物細胞用遺伝子導入ベクター |
EP3794128A1 (en) * | 2018-05-18 | 2021-03-24 | Sorbonne Universite | Molecular tools and methods for transgene integration and their transposition dependent expression |
EP3844272A1 (en) * | 2018-08-28 | 2021-07-07 | Flagship Pioneering Innovations VI, LLC | Methods and compositions for modulating a genome |
CN113348248A (zh) | 2018-10-24 | 2021-09-03 | 思兰克斯有限公司 | 表达***、重组细胞及其用途 |
CA3125047A1 (en) * | 2019-04-08 | 2020-10-15 | Dna Twopointo Inc. | Integration of nucleic acid constructs into eukaryotic cells with a transposase from oryzias |
CN112513277B (zh) * | 2019-04-08 | 2024-07-23 | Dna2.0股份有限公司 | 使用来自螟蛾属的转座酶将核酸构建体转座入真核基因组 |
CN111909986B (zh) * | 2019-05-10 | 2024-03-26 | 潘雨堃 | 一种基因治疗安全评估与毒副作用预防的方法 |
JP2021016370A (ja) * | 2019-07-23 | 2021-02-15 | 株式会社東芝 | 核酸導入キャリア、核酸導入キャリアセット、核酸導入組成物及び核酸導入方法 |
JP2021016371A (ja) * | 2019-07-23 | 2021-02-15 | 株式会社東芝 | Car−t細胞の製造方法、核酸導入キャリア及びキット |
WO2021164704A2 (en) * | 2020-02-19 | 2021-08-26 | Wuxi Biologics (Shanghai) Co., Ltd. | Enhanced expression system and methods of use thereof |
CN113584083A (zh) | 2020-04-30 | 2021-11-02 | 深圳市深研生物科技有限公司 | 用于逆转录病毒载体的生产细胞和包装细胞及其制备方法 |
CN111534542A (zh) * | 2020-05-07 | 2020-08-14 | 西南大学 | piggyBac转座子***介导的真核生物转基因细胞系及构建方法 |
CN113930446B (zh) * | 2020-07-13 | 2024-06-28 | 未来模式(苏州)生物科技有限公司 | 对非人动物基因改造的方法及构建的免疫缺陷动物模型 |
AU2022343729A1 (en) | 2021-09-09 | 2024-03-21 | Iovance Biotherapeutics, Inc. | Processes for generating til products using pd-1 talen knockdown |
WO2023147488A1 (en) | 2022-01-28 | 2023-08-03 | Iovance Biotherapeutics, Inc. | Cytokine associated tumor infiltrating lymphocytes compositions and methods |
WO2024112571A2 (en) | 2022-11-21 | 2024-05-30 | Iovance Biotherapeutics, Inc. | Two-dimensional processes for the expansion of tumor infiltrating lymphocytes and therapies therefrom |
WO2024118836A1 (en) | 2022-11-30 | 2024-06-06 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes with shortened rep step |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6218185B1 (en) * | 1996-04-19 | 2001-04-17 | The United States Of America As Represented By The Secretary Of Agriculture | Piggybac transposon-based genetic transformation system for insects |
US20030150007A1 (en) * | 2000-03-21 | 2003-08-07 | Charalambos Savakis | Method of generating transgenic organisms using transposons |
US6962810B2 (en) * | 2000-10-31 | 2005-11-08 | University Of Notre Dame Du Lac | Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac |
DK1465993T3 (da) * | 2002-01-09 | 2010-01-11 | Minos Biosystems Ltd | Inducerbar transposition hos transgen organisme ved anvendelse af transposonvektor |
CN1234871C (zh) * | 2003-03-27 | 2006-01-04 | 成都天创生物科技有限责任公司 | 一种解毒酶基因在家蚕中稳定表达***的构建方法 |
-
2005
- 2005-05-14 CN CN2005800510732A patent/CN101297031B/zh active Active
- 2005-05-14 US US11/920,410 patent/US20100154070A1/en not_active Abandoned
- 2005-05-14 JP JP2008510382A patent/JP2008545375A/ja not_active Abandoned
- 2005-05-14 CA CA002608481A patent/CA2608481A1/en not_active Abandoned
- 2005-05-14 BR BRPI0520212-4A patent/BRPI0520212A2/pt not_active IP Right Cessation
- 2005-05-14 WO PCT/CN2005/000674 patent/WO2006122442A1/en active Application Filing
- 2005-05-14 EP EP05745159A patent/EP1896578A4/en not_active Withdrawn
- 2005-05-14 MX MX2007014139A patent/MX2007014139A/es not_active Application Discontinuation
- 2005-05-14 AU AU2005331864A patent/AU2005331864A1/en not_active Abandoned
-
2007
- 2007-11-13 IL IL187348A patent/IL187348A0/en unknown
- 2007-12-14 NO NO20076465A patent/NO20076465L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL187348A0 (en) | 2008-04-13 |
WO2006122442A1 (en) | 2006-11-23 |
US20100154070A1 (en) | 2010-06-17 |
JP2008545375A (ja) | 2008-12-18 |
CN101297031B (zh) | 2013-06-05 |
CN101297031A (zh) | 2008-10-29 |
EP1896578A4 (en) | 2008-11-05 |
AU2005331864A1 (en) | 2006-11-23 |
CA2608481A1 (en) | 2006-11-23 |
BRPI0520212A2 (pt) | 2009-08-18 |
EP1896578A1 (en) | 2008-03-12 |
MX2007014139A (es) | 2008-10-09 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |