NO20064933L - Makrosykliske forbindelser som inhibitorer av viral replikasjon - Google Patents

Makrosykliske forbindelser som inhibitorer av viral replikasjon

Info

Publication number
NO20064933L
NO20064933L NO20064933A NO20064933A NO20064933L NO 20064933 L NO20064933 L NO 20064933L NO 20064933 A NO20064933 A NO 20064933A NO 20064933 A NO20064933 A NO 20064933A NO 20064933 L NO20064933 L NO 20064933L
Authority
NO
Norway
Prior art keywords
methods
inhibitors
viral replication
macrocyclic compounds
compound
Prior art date
Application number
NO20064933A
Other languages
English (en)
Inventor
Steven Wade Andrews
Lawrence M Blatt
Steven Mark Wenglowsky
Yutong Jiang
April Layne Kennedy
Kevin Ronald Condroski
John Anthony Josey
Peter J Stengel
George Andrew Doherty
Benjamin T Woodard
Machender R Madduru
Original Assignee
Intermune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intermune Inc filed Critical Intermune Inc
Publication of NO20064933L publication Critical patent/NO20064933L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Det tilveiebringes forbindelser med den generelle formel I, så vel som preparater inkludert farmasøytiske preparater, inneholdende en slik forbindelse. Det tilveiebringes videre behandlingsmetoder inkludert metoder for behanding av flaviviral infeksjon, inkludert hepatitt C-virusinfeksjon, samt metoder for behandling av leverfibrose, der metodene generelt inkluderer administrering til et individ som trenger det, av en effektiv mengde av en angjeldende forbindelse eller et preparat inneholdende en slik.
NO20064933A 2004-03-30 2006-10-27 Makrosykliske forbindelser som inhibitorer av viral replikasjon NO20064933L (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US55816104P 2004-03-30 2004-03-30
US56241804P 2004-04-14 2004-04-14
US61238104P 2004-09-22 2004-09-22
US61246004P 2004-09-22 2004-09-22
PCT/US2005/010494 WO2005095403A2 (en) 2004-03-30 2005-03-29 Macrocyclic compounds as inhibitors of viral replication

Publications (1)

Publication Number Publication Date
NO20064933L true NO20064933L (no) 2006-12-15

Family

ID=35005653

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20064933A NO20064933L (no) 2004-03-30 2006-10-27 Makrosykliske forbindelser som inhibitorer av viral replikasjon

Country Status (16)

Country Link
EP (1) EP1749007A2 (no)
JP (1) JP4950026B2 (no)
AP (1) AP2006003763A0 (no)
AR (1) AR050321A1 (no)
AU (1) AU2005228894B9 (no)
BR (1) BRPI0509467A (no)
CA (1) CA2560897C (no)
CU (1) CU23787B7 (no)
EA (1) EA012389B1 (no)
EC (1) ECSP066959A (no)
GE (1) GEP20104926B (no)
IL (1) IL177917A0 (no)
MA (1) MA28548B1 (no)
NO (1) NO20064933L (no)
NZ (1) NZ549697A (no)
WO (1) WO2005095403A2 (no)

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Also Published As

Publication number Publication date
AP2006003763A0 (en) 2006-10-31
ECSP066959A (es) 2006-12-20
BRPI0509467A (pt) 2007-09-11
AU2005228894A1 (en) 2005-10-13
WO2005095403A3 (en) 2005-12-01
EA200601467A1 (ru) 2007-06-29
IL177917A0 (en) 2006-12-31
CA2560897C (en) 2012-06-12
EP1749007A2 (en) 2007-02-07
GEP20104926B (en) 2010-03-25
MA28548B1 (fr) 2007-04-03
AU2005228894B9 (en) 2011-10-13
AR050321A1 (es) 2006-10-18
JP2007531749A (ja) 2007-11-08
CU23787B7 (es) 2012-03-15
CU20090209A7 (es) 2011-04-26
NZ549697A (en) 2009-12-24
WO2005095403A2 (en) 2005-10-13
EA012389B1 (ru) 2009-10-30
CA2560897A1 (en) 2005-10-13
JP4950026B2 (ja) 2012-06-13
AU2005228894B2 (en) 2011-08-25

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