NO20053864L - Fremgangsmater og blandinger for behandling av gastrointestinale forstyrrelser. - Google Patents
Fremgangsmater og blandinger for behandling av gastrointestinale forstyrrelser.Info
- Publication number
- NO20053864L NO20053864L NO20053864A NO20053864A NO20053864L NO 20053864 L NO20053864 L NO 20053864L NO 20053864 A NO20053864 A NO 20053864A NO 20053864 A NO20053864 A NO 20053864A NO 20053864 L NO20053864 L NO 20053864L
- Authority
- NO
- Norway
- Prior art keywords
- disorders
- constipation
- conditions
- compositions
- gastrointestinal disorders
- Prior art date
Links
- 208000018522 Gastrointestinal disease Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 206010010774 Constipation Diseases 0.000 abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 208000035475 disorder Diseases 0.000 abstract 3
- 102100034605 Atrial natriuretic peptide receptor 3 Human genes 0.000 abstract 2
- 101000924488 Homo sapiens Atrial natriuretic peptide receptor 3 Proteins 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 208000021302 gastroesophageal reflux disease Diseases 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 206010009900 Colitis ulcerative Diseases 0.000 abstract 1
- 201000005078 Colonic Pseudo-Obstruction Diseases 0.000 abstract 1
- 208000011231 Crohn disease Diseases 0.000 abstract 1
- 206010017943 Gastrointestinal conditions Diseases 0.000 abstract 1
- 208000017228 Gastrointestinal motility disease Diseases 0.000 abstract 1
- 206010021518 Impaired gastric emptying Diseases 0.000 abstract 1
- 201000006704 Ulcerative Colitis Diseases 0.000 abstract 1
- 208000014797 chronic intestinal pseudoobstruction Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 201000006549 dyspepsia Diseases 0.000 abstract 1
- 208000001288 gastroparesis Diseases 0.000 abstract 1
- 230000002981 neuropathic effect Effects 0.000 abstract 1
- 229940127240 opiate Drugs 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Foreliggende oppfinnelse angår blandinger og relaterte fremgangsmåter for behandling av IBS og andre gastrointestinale forstyrrelser og tilstander (for eksempel gastrointestinale motilitetsfortyrrelser, funksjonelle gastrointestinale forstyrrelser, gastroøsofagal reflukssykdom (GERD), Crohns sykdom, colitis ulcerosa, inflammatorisk tarmsykdom, funksjonell kardialgi, dyspepsi (inkludert funksjonell dyspepsi og non-ulcer dyspepsi), gastroparese, kronisk intestinal pseudoobstruksjon (eller colonisk pseudoobstruksjon), og lidelser og tilstander forbundet med konstipasjon, for eksempel konstipasjon forbundet med anvendelse av opiat smertestillende, post-kirurgisk konstipasjon, og konstipasjon forbundet med neuropatiske lidelser så vel som andre tilstander og forstyrrelser ved anvendelse av peptider og andre agenser som aktiverer guanylat syklase C (GCC)-reseptoren.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44309803P | 2003-01-28 | 2003-01-28 | |
US47128803P | 2003-05-15 | 2003-05-15 | |
US51946003P | 2003-11-12 | 2003-11-12 | |
PCT/US2004/002390 WO2004069165A2 (en) | 2003-01-28 | 2004-01-28 | Methods and compositions for the treatment of gastrointestinal disorders |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20053864D0 NO20053864D0 (no) | 2005-08-18 |
NO20053864L true NO20053864L (no) | 2005-10-26 |
NO334112B1 NO334112B1 (no) | 2013-12-09 |
Family
ID=32854294
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20053864A NO334112B1 (no) | 2003-01-28 | 2005-08-18 | Renset polypeptid og farmasøytisk blanding anvendelig for behandling av gastrointestinale forstyrrelser. |
NO20130460A NO336768B1 (no) | 2003-01-28 | 2013-04-05 | Farmasøytisk preparat, fremgangsmåte for fremstilling og produsering av et polypeptid, samt polypeptidet. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20130460A NO336768B1 (no) | 2003-01-28 | 2013-04-05 | Farmasøytisk preparat, fremgangsmåte for fremstilling og produsering av et polypeptid, samt polypeptidet. |
Country Status (29)
Country | Link |
---|---|
US (3) | US20040266989A1 (no) |
EP (3) | EP2246360B1 (no) |
JP (3) | JP4584911B2 (no) |
KR (2) | KR101227627B1 (no) |
CN (2) | CN100589839C (no) |
AT (2) | ATE365174T1 (no) |
AU (2) | AU2004210161B2 (no) |
BE (1) | BE2013C032I2 (no) |
BR (2) | BR122018074353B8 (no) |
CA (1) | CA2514507C (no) |
CY (5) | CY1110905T1 (no) |
DE (2) | DE602004028678D1 (no) |
DK (3) | DK2246360T3 (no) |
ES (3) | ES2350123T3 (no) |
FR (2) | FR13C0029I2 (no) |
HK (1) | HK1078768A1 (no) |
HU (1) | HUS1300022I1 (no) |
IL (2) | IL169863A (no) |
LT (1) | LTC1594517I2 (no) |
LU (2) | LU92201I2 (no) |
MX (1) | MXPA05008097A (no) |
NL (1) | NL300593I2 (no) |
NO (2) | NO334112B1 (no) |
NZ (2) | NZ570134A (no) |
PT (3) | PT1911763E (no) |
RU (2) | RU2353383C2 (no) |
SG (2) | SG168407A1 (no) |
SI (3) | SI2246360T1 (no) |
WO (1) | WO2004069165A2 (no) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2944648B1 (en) | 2001-03-29 | 2019-11-13 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists for the treatment of organ inflammation |
US20060281682A1 (en) * | 2003-01-28 | 2006-12-14 | Currie Mark G | Methods and compositions for the treatment of gastrointestinal disorders |
US7371727B2 (en) * | 2003-01-28 | 2008-05-13 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US7304036B2 (en) | 2003-01-28 | 2007-12-04 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
MXPA05008097A (es) * | 2003-01-28 | 2006-02-08 | Microbia Inc | Metodos y composiciones para el tratamiento de desordenes gastrointestinales. |
US7772188B2 (en) * | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
DK1644021T3 (da) | 2003-06-13 | 2012-10-29 | Ironwood Pharmaceuticals Inc | Fremgangsmåder og sammensætninger til behandlingen af gastrointestinale sygdomme |
US7494979B2 (en) * | 2003-06-13 | 2009-02-24 | Ironwood Pharmaceuticals, Inc. | Method for treating congestive heart failure and other disorders |
US20050266028A1 (en) * | 2004-05-25 | 2005-12-01 | University Of Georgia Research Foundation, Inc. | Compositions and methods for modulating an immune response |
EP1813271A4 (en) * | 2004-10-26 | 2008-05-21 | Ajinomoto Kk | PREVENTIVE / THERAPEUTIC AGENT FOR VISCERAL PAIN |
EP1940441A4 (en) * | 2005-08-19 | 2010-01-27 | Ironwood Pharmaceuticals Inc | COMPOSITIONS AND METHODS FOR TREATING GASTROINTESTINAL DISORDERS |
PT1937262T (pt) | 2005-09-29 | 2019-08-21 | Ipsen Pharma Sas | Composição para utilização no tratamento de dismotilidade gastrointestinal |
EP1996218A4 (en) * | 2006-02-24 | 2012-07-11 | Ironwood Pharmaceuticals Inc | METHODS AND COMPOSITIONS FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS |
WO2008106429A2 (en) * | 2007-02-26 | 2008-09-04 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of heart failure and other disorders |
MX2009011898A (es) * | 2007-05-04 | 2009-11-18 | Ironwood Pharmaceuticals Inc | Composiciones y metodos para tratar trastornos asociados con retencion de sal o fluido. |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
CA2688161C (en) | 2007-06-04 | 2020-10-20 | Kunwar Shailubhai | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
ES2522968T3 (es) | 2008-06-04 | 2014-11-19 | Synergy Pharmaceuticals Inc. | Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
WO2009149278A1 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US20110306125A1 (en) * | 2008-06-30 | 2011-12-15 | Ironwood Pharmaceuticals, Inc. | Protein Expression Methods |
ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
CA2732892C (en) * | 2008-08-15 | 2020-12-15 | Forest Laboratories Holdings Limited | Stable solid formulation of a gc-c receptor agonist polypeptide suitable for oral administration |
US8222201B2 (en) | 2008-11-19 | 2012-07-17 | Ritesh Sanghvi | Crystalline form of linaclotide |
ES2608050T3 (es) * | 2008-12-03 | 2017-04-05 | Synergy Pharmaceuticals Inc. | Formulaciones de agonistas de guanilato ciclasa C y métodos de uso |
ES2439998T3 (es) | 2009-04-10 | 2014-01-27 | Corden Pharma Colorado, Inc. | Procedimiento para aislar linaclotida |
US8748573B2 (en) * | 2009-08-06 | 2014-06-10 | Ironwood Pharmaceuticals, Inc. | Formulations comprising linaclotide |
RU2012109415A (ru) * | 2009-08-13 | 2013-09-20 | Айронвуд Фармасьютикалз, Инк. | Способ модуляции фармакодинамического эффекта перорально вводимых агонистов рецептора гуанилатциклазы |
EP2499154B1 (en) * | 2009-11-09 | 2016-12-21 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
KR20120103689A (ko) * | 2009-12-07 | 2012-09-19 | 아이언우드 파마슈티컬스, 인코포레이티드 | 위장 장애의 치료 |
AU2011218009B2 (en) | 2010-02-17 | 2016-11-03 | Ironwood Pharmaceuticals, Inc | Treatments for gastrointestinal disorders |
WO2011145062A1 (en) | 2010-05-21 | 2011-11-24 | Link Research & Grants Corporation | Treatment of tinnitus and related auditory dysfunctions |
US8748575B2 (en) * | 2010-06-09 | 2014-06-10 | Combimab, Inc. | Therapeutic peptides |
PL2603232T3 (pl) | 2010-08-11 | 2020-05-18 | Ironwood Pharmaceuticals, Inc. | Stabilne formulacje linaklotydu |
CA2810243C (en) | 2010-09-15 | 2021-04-20 | Synergy Pharmaceuticals Inc. | Formulations of guanylate cyclase c agonists and methods of use |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
CA2835624A1 (en) | 2011-05-11 | 2012-11-15 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
US9303066B2 (en) | 2011-05-11 | 2016-04-05 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
US9527887B2 (en) | 2011-06-08 | 2016-12-27 | Ironwood Pharmaceutical, Inc. | Treatments for gastrointestinal disorders |
US9617305B2 (en) | 2011-06-08 | 2017-04-11 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
MD480Z (en) * | 2011-07-07 | 2012-09-30 | Elvira Andon | Method for treating acute ulcerative nonspecific colitis |
EP2776055B1 (en) | 2011-08-17 | 2016-12-14 | Ironwood Pharmaceuticals, Inc. | Treatments for gastrointestinal disorders |
EA022546B1 (ru) * | 2011-09-28 | 2016-01-29 | Федеральное Государственное Бюджетное Учреждение Науки Институт Биоорганической Химии Им. Академиков М.М. Шемякина И Ю.А. Овчинникова Российской Академии Наук | Способ торможения роста карциномы эрлиха у лабораторного животного |
JP2016521249A (ja) * | 2012-07-12 | 2016-07-21 | フォレスト ラボラトリーズ ホールディングス リミテッド | リナクロチド組成物 |
RU2528641C2 (ru) * | 2012-08-22 | 2014-09-20 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежская государственная медицинская академия им. Н.Н. Бурденко" Министерства здравоохранения и социального развития Российской Федерации | Способ лечения больных с синдромом диспепсии в сочетании с избыточной массой тела |
CN102875655B (zh) * | 2012-09-29 | 2014-12-17 | 深圳翰宇药业股份有限公司 | 一种合成利那洛肽的方法 |
EP2950803A1 (en) | 2013-01-30 | 2015-12-09 | Sandoz AG | Crystalline form of linaclotide |
EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
MX2016001714A (es) | 2013-08-09 | 2016-10-03 | Ardelyx Inc | Compuestos y metodos para inhibir el transporte de fosfato. |
FI3288578T3 (fi) * | 2015-05-01 | 2023-05-03 | Ironwood Pharmaceuticals Inc | Koostumuksia paksusuolen puhdistukseen ja gastrointestinaalisten häiriöiden hoitoon |
EP3430056A4 (en) * | 2016-03-15 | 2019-11-20 | The Regents of the University of California | METHOD AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF ALPHA-8-BETA-1-INTEGRIN ASSOCIATED DISEASES |
CN107929718A (zh) * | 2017-10-19 | 2018-04-20 | 南京星银药业集团有限公司 | Glp‑1类似物及gc‑c受体激动剂组合物缓释制剂及其制备方法 |
CN117599320A (zh) * | 2018-10-23 | 2024-02-27 | 艾比科生物医学公司 | 输送装置 |
CN109467606A (zh) * | 2018-11-15 | 2019-03-15 | 大连理工大学 | 一种大肠杆菌肠毒素STa-LTB-STb融合蛋白及其编码基因和应用 |
WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
RU2712761C1 (ru) * | 2019-07-02 | 2020-01-31 | Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) | Средство для стимуляции регенерации эндотелия легких при сочетании метаболического синдрома и хронической обструктивной болезни легких |
CN111265653B (zh) * | 2020-02-09 | 2023-05-09 | 华中科技大学同济医学院附属协和医院 | 心房利钠肽在制备炎症性肠病治疗药物中的应用 |
WO2021191865A1 (en) * | 2020-03-26 | 2021-09-30 | Dusa Pharmaceuticals, Inc. | Management of dermal neurofibromatosis lesions |
WO2023144292A1 (en) | 2022-01-28 | 2023-08-03 | Fresenius Kabi Ipsum S.R.L. | Process for the preparation of linaclotide |
Family Cites Families (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US266989A (en) * | 1882-11-07 | Automatic fire | ||
US152868A (en) * | 1874-07-07 | Improvement in type-setting machines | ||
US258687A (en) * | 1882-05-30 | Grain-binder | ||
US232013A (en) * | 1880-09-07 | Henry h | ||
US32684A (en) * | 1861-07-02 | Stump-extkactob | ||
US73628A (en) * | 1868-01-21 | mitchell | ||
US121961A (en) * | 1871-12-19 | Improvement in devices for supporting pipe-cores | ||
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
US6342373B1 (en) * | 1983-11-21 | 2002-01-29 | Ucp Gen-Pharma Ag | Process for preparing recombinant eglin, protease inhibitor |
IT1217123B (it) | 1987-02-05 | 1990-03-14 | Rotta Research Lab | Derivati otticamente attivi dell acido 5 pentilammino 5 oxo pentanoico r ad attivita antagonista della colecistochinina e procedimento per la loro preparazione |
GB2209937B (en) | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
CH679207A5 (no) | 1989-07-28 | 1992-01-15 | Debiopharm Sa | |
CA2046830C (en) | 1990-07-19 | 1999-12-14 | Patrick P. Deluca | Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer |
HUT64023A (en) | 1991-03-22 | 1993-11-29 | Sandoz Ag | Process for producing aminoguanidine derivatives and pharmaceutical compositions comprising such compounds |
FR2674849B1 (fr) | 1991-04-02 | 1994-12-23 | Logeais Labor Jacques | Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique. |
CH683149A5 (fr) | 1991-07-22 | 1994-01-31 | Debio Rech Pharma Sa | Procédé pour la préparation de microsphères en matériau polymère biodégradable. |
US5140102A (en) | 1991-09-23 | 1992-08-18 | Monsanto Company | Pentadecapeptide, guanylin, which stimulates intestinal guanylate cyclase |
CA2124958C (en) * | 1991-12-02 | 2007-02-13 | Vanitha Ramakrishnan | Inhibitory immunoglobulin polypeptides to human pdgf beta receptor |
CA2151741C (en) | 1991-12-30 | 2001-12-11 | Alan Justice | Methods of producing analgesia and enhancing opiate analgesia |
US5824645A (en) | 1991-12-30 | 1998-10-20 | Neurex Corporation | Method of treating inflammation |
GB9211268D0 (en) | 1992-05-28 | 1992-07-15 | Ici Plc | Salts of basic peptides with carboxyterminated polyesters |
US5969097A (en) | 1992-06-23 | 1999-10-19 | G. D. Searle & Co. | Human guanylin |
PL174772B1 (pl) | 1993-01-06 | 1998-09-30 | Kinerton Ltd | Kompozycja farmaceutyczna zawierająca jonowy konjugat cząsteczkowy |
US5672659A (en) | 1993-01-06 | 1997-09-30 | Kinerton Limited | Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides |
US5395490A (en) | 1993-05-14 | 1995-03-07 | Intertec, Ltd. | Method for treating materials by the application of electromagnetic energy at resonant absorption frequencies |
CA2174928C (en) * | 1993-10-26 | 2011-08-16 | Scott A. Waldman | Compositions that specifically bind to colorectal cancer cells and methods of using the same |
US5489670A (en) * | 1993-10-29 | 1996-02-06 | G. D. Searle & Co. | Human uroguanylin |
US5610145A (en) | 1994-04-15 | 1997-03-11 | Warner-Lambert Company | Tachykinin antagonists |
US5612052A (en) | 1995-04-13 | 1997-03-18 | Poly-Med, Inc. | Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof |
PT835126E (pt) | 1995-06-27 | 2003-07-31 | Elan Pharm Inc | Composicoes e formulacoes para a producao de analgesia e para a inibicao de patologias dolorosas neuropaticas |
US6054429A (en) | 1996-03-08 | 2000-04-25 | Elan Pharmaceuticals, Inc. | Epidural method of producing analgesia |
US5795864A (en) | 1995-06-27 | 1998-08-18 | Neurex Corporation | Stable omega conopetide formulations |
US6277862B1 (en) | 1995-11-24 | 2001-08-21 | Smithkline Beecham S.P.A. | Quinoline derivatives |
GB9524104D0 (en) | 1995-11-24 | 1996-01-24 | Smithkline Beecham Spa | Novel compounds |
CA2250981C (en) | 1996-04-23 | 2002-07-02 | Kinerton Limited | Acidic polylactic polymers |
US6589750B2 (en) | 1997-02-20 | 2003-07-08 | Institut Pasteur | Therapeutic use of the SMR1 protein, the SMR1 maturation products, specifically the QHNPR pentapeptide as well as its biologically active derivatives |
ES2302350T3 (es) | 1997-02-28 | 2008-07-01 | Nycomed Gmbh | Combinacion sinergica de inhibidores de pde y agonistas de adenilatociclasa o agonistas de guanililciclasa. |
US5893985A (en) | 1997-03-14 | 1999-04-13 | The Lincoln Electric Company | Plasma arc torch |
NZ329807A (en) | 1997-04-23 | 2000-07-28 | Pfizer | NK-1 receptor antagonists and P receptor antagonists 2-Diarylmethyl-3-amino-1-azabicyclo[2.2.2]octane derivatives and amino substituted N-containing rings as agents for treating irritable bowel syndrome |
EP1012188B1 (de) | 1997-09-12 | 2004-08-18 | Pharis Biotec GmbH | Zusammensetzung zur therapie von diabetes mellitus und fettsucht |
US20010006972A1 (en) | 1998-04-21 | 2001-07-05 | Stephen A. Williams | Nk-1 receptor antagonists for the treatment of symptoms of irritable bowel syndrome |
IT1304152B1 (it) | 1998-12-10 | 2001-03-08 | Mediolanum Farmaceutici Srl | Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato |
PT1593387E (pt) | 1999-06-23 | 2009-03-18 | Pasteur Institut | Composições para o tratamento de desordens comportamentais e deficiências interpessoais. |
WO2001012233A2 (en) | 1999-08-18 | 2001-02-22 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Sustained release formulation of a peptide |
SE9903291D0 (sv) | 1999-09-15 | 1999-09-15 | Astra Ab | New process |
JP2003516316A (ja) | 1999-10-06 | 2003-05-13 | ファルマシア コーポレイション | 腸癌阻止剤としてのウログアニリン |
DE60013630T2 (de) | 1999-11-01 | 2005-09-15 | John Cardiff Rhodes | Arzneimittel zur behandlung von darmverstopfung und reizkolon |
AUPQ514600A0 (en) | 2000-01-18 | 2000-02-10 | James Cook University | Brain injury treatment |
AU3580001A (en) | 2000-03-01 | 2001-09-12 | University College London | Modulators of the endocannabinoid uptake and of the vallinoid receptors |
DE60018085T2 (de) | 2000-12-22 | 2005-07-07 | Institut Pasteur | Prozess zum Screening von Molekülen, die spezifisch an die NEP-Bindungsstelle des QHNPR-pentapeptides binden |
AU2002235520A1 (en) | 2001-02-02 | 2002-08-19 | Pharmacia Corporation | Uroguanylin and cyclooxygenase-2 inhibitor combinations for inhibition of intestinal cancer |
EP2944648B1 (en) * | 2001-03-29 | 2019-11-13 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists for the treatment of organ inflammation |
EP1451211A2 (en) * | 2001-03-30 | 2004-09-01 | University of Copenhagen | Compositions and methods for modulating guanylyl cyclase signaling receptor (gc-c) activity and for treating meniere's disease |
MY134211A (en) | 2001-05-18 | 2007-11-30 | Smithkline Beecham Corp | Novel use |
WO2002098912A2 (de) * | 2001-06-05 | 2002-12-12 | Yalcin Cetin | Luftseitig verabreichte guanylat cyclase c liganden für atemwegserkrankungen |
FR2830451B1 (fr) | 2001-10-09 | 2004-04-30 | Inst Nat Sante Rech Med | Utilisation de peptides analogues de la thymuline(pat)pour la fabrication de medicaments contre la douleur |
EP1321142A1 (en) | 2001-12-21 | 2003-06-25 | Novartis AG | Solid pharmaceutical composition for oral administration of Tegaserod |
US20040121961A1 (en) * | 2002-02-04 | 2004-06-24 | Jaime Masferrer | Uroguanylin and cyclooxygenase-2 inhibitor combinations for inhibition of intestinal cancer |
US20030232013A1 (en) * | 2002-02-22 | 2003-12-18 | Gary Sieckman | Therapeutic and diagnostic targeting of cancers cells with tumor homing peptides |
EP1531846A4 (en) | 2002-02-27 | 2006-04-19 | Us Gov Health & Human Serv | CONJUGATES OF LIGAND, LINK AND CYTOTOXIC AGENS, AND RELATED COMPOSITIONS AND USE PROCESSES |
WO2003077897A1 (en) | 2002-03-15 | 2003-09-25 | Cypress Bioscience, Inc. | Ne and 5-ht reuptake inhibitors for treating visceral pain syndromes |
PL371596A1 (en) | 2002-05-17 | 2005-06-27 | Merck Patent Gmbh | Use of compounds that are effective as selective opiate receptor modulators |
US20060281682A1 (en) * | 2003-01-28 | 2006-12-14 | Currie Mark G | Methods and compositions for the treatment of gastrointestinal disorders |
US7304036B2 (en) * | 2003-01-28 | 2007-12-04 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
MXPA05008097A (es) * | 2003-01-28 | 2006-02-08 | Microbia Inc | Metodos y composiciones para el tratamiento de desordenes gastrointestinales. |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US7371727B2 (en) * | 2003-01-28 | 2008-05-13 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
US8206704B2 (en) * | 2003-02-10 | 2012-06-26 | Thomas Jefferson University | Use of GCC ligands |
EP1940441A4 (en) | 2005-08-19 | 2010-01-27 | Ironwood Pharmaceuticals Inc | COMPOSITIONS AND METHODS FOR TREATING GASTROINTESTINAL DISORDERS |
-
2004
- 2004-01-28 MX MXPA05008097A patent/MXPA05008097A/es active IP Right Grant
- 2004-01-28 PT PT07011869T patent/PT1911763E/pt unknown
- 2004-01-28 JP JP2006503109A patent/JP4584911B2/ja not_active Expired - Lifetime
- 2004-01-28 NZ NZ570134A patent/NZ570134A/en not_active IP Right Cessation
- 2004-01-28 PT PT10170038T patent/PT2246360E/pt unknown
- 2004-01-28 DK DK10170038.3T patent/DK2246360T3/da active
- 2004-01-28 ES ES07011869T patent/ES2350123T3/es not_active Expired - Lifetime
- 2004-01-28 RU RU2005127058/15A patent/RU2353383C2/ru active
- 2004-01-28 BR BR122018074353A patent/BR122018074353B8/pt active IP Right Grant
- 2004-01-28 NZ NZ541595A patent/NZ541595A/en not_active IP Right Cessation
- 2004-01-28 DE DE602004028678T patent/DE602004028678D1/de not_active Expired - Lifetime
- 2004-01-28 SI SI200431918T patent/SI2246360T1/sl unknown
- 2004-01-28 EP EP10170038A patent/EP2246360B1/en not_active Expired - Lifetime
- 2004-01-28 SG SG200705302-8A patent/SG168407A1/en unknown
- 2004-01-28 SI SI200430401T patent/SI1594517T1/sl unknown
- 2004-01-28 DE DE602004007105T patent/DE602004007105T2/de not_active Expired - Lifetime
- 2004-01-28 EP EP07011869A patent/EP1911763B1/en not_active Expired - Lifetime
- 2004-01-28 PT PT04706011T patent/PT1594517E/pt unknown
- 2004-01-28 AT AT04706011T patent/ATE365174T1/de active
- 2004-01-28 US US10/766,735 patent/US20040266989A1/en not_active Abandoned
- 2004-01-28 ES ES04706011T patent/ES2285417T3/es not_active Expired - Lifetime
- 2004-01-28 SG SG2012003802A patent/SG192300A1/en unknown
- 2004-01-28 CN CN200480008533A patent/CN100589839C/zh not_active Expired - Lifetime
- 2004-01-28 CA CA2514507A patent/CA2514507C/en not_active Expired - Lifetime
- 2004-01-28 AT AT07011869T patent/ATE477268T1/de active
- 2004-01-28 EP EP04706011A patent/EP1594517B1/en not_active Expired - Lifetime
- 2004-01-28 DK DK07011869.0T patent/DK1911763T3/da active
- 2004-01-28 BR BRPI0407071A patent/BRPI0407071B8/pt active IP Right Grant
- 2004-01-28 DK DK04706011T patent/DK1594517T3/da active
- 2004-01-28 ES ES10170038T patent/ES2387848T3/es not_active Expired - Lifetime
- 2004-01-28 CN CN2009102662250A patent/CN101787073B/zh not_active Expired - Lifetime
- 2004-01-28 RU RU2008147983/15A patent/RU2543350C2/ru active
- 2004-01-28 SI SI200431521T patent/SI1911763T1/sl unknown
- 2004-01-28 KR KR1020117019764A patent/KR101227627B1/ko active IP Right Grant
- 2004-01-28 AU AU2004210161A patent/AU2004210161B2/en active Active
- 2004-01-28 KR KR1020057013966A patent/KR101227626B1/ko active IP Right Grant
- 2004-01-28 WO PCT/US2004/002390 patent/WO2004069165A2/en active Application Filing
-
2005
- 2005-07-25 IL IL169863A patent/IL169863A/en active IP Right Grant
- 2005-08-18 NO NO20053864A patent/NO334112B1/no not_active IP Right Cessation
- 2005-11-23 HK HK05110618A patent/HK1078768A1/xx not_active IP Right Cessation
-
2007
- 2007-08-09 CY CY20071101072T patent/CY1110905T1/el unknown
- 2007-10-31 US US11/930,696 patent/US7704947B2/en not_active Expired - Lifetime
-
2009
- 2009-11-10 AU AU2009235993A patent/AU2009235993B2/en active Active
-
2010
- 2010-04-05 US US12/754,138 patent/US8080526B2/en not_active Expired - Lifetime
- 2010-06-22 JP JP2010141519A patent/JP5563384B2/ja not_active Expired - Lifetime
- 2010-11-04 CY CY20101101000T patent/CY1111058T1/el unknown
-
2012
- 2012-08-09 IL IL221380A patent/IL221380A0/en active IP Right Grant
- 2012-09-19 CY CY20121100859T patent/CY1113217T1/el unknown
-
2013
- 2013-02-28 JP JP2013038602A patent/JP5748791B2/ja not_active Expired - Lifetime
- 2013-04-05 NO NO20130460A patent/NO336768B1/no not_active IP Right Cessation
- 2013-05-22 LT LTPA2013013C patent/LTC1594517I2/lt unknown
- 2013-05-22 HU HUS1300022 patent/HUS1300022I1/hu unknown
- 2013-05-22 LU LU92201C patent/LU92201I2/fr unknown
- 2013-05-22 NL NL300593C patent/NL300593I2/nl unknown
- 2013-05-22 LU LU92200C patent/LU92200I2/fr unknown
- 2013-05-23 FR FR13C0029C patent/FR13C0029I2/fr active Active
- 2013-05-23 FR FR13C0030C patent/FR13C0030I1/fr active Active
- 2013-05-24 CY CY2013022C patent/CY2013022I1/el unknown
- 2013-05-24 CY CY2013021C patent/CY2013021I1/el unknown
- 2013-05-24 BE BE2013C032C patent/BE2013C032I2/nl unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20053864L (no) | Fremgangsmater og blandinger for behandling av gastrointestinale forstyrrelser. | |
NO20064121L (no) | Fremgangsmate og sammensetninger for behandling av gastrointestinale forstyrrelser | |
WO2007022531A3 (en) | Methods and compositions for the treatment of gastrointestinal disorders | |
WO2006086653A3 (en) | Methods and compositions for the treatment of gastrointestinal disorders | |
WO2005016244A3 (en) | Methods and compositions for the treatment of gastrointestinal disorders | |
WO2007101158A3 (en) | Methods and compositions for the treatment of gastrointestinal disorders | |
WO2008002971A3 (en) | Methods and compositions for the treatment of gastrointestinal disorders | |
WO2011103311A3 (en) | Treatments for gastrointestinal disorders | |
MX2014001798A (es) | Tratamientos para trastornos gastrointestinales. | |
WO2005074575A3 (en) | Methods and compositions for the treatment of gastrointestinal disorders | |
TW200745031A (en) | Acyl indoles, compositions containing such compounds and methods of use | |
WO2006102069A3 (en) | Methods and compositions for the treatment of hypertension and gastrointestinal disorders | |
WO2007062168A3 (en) | Methods and compositions for the treatment of gastrointestinal disorders | |
CY1113569T1 (el) | Μεθοδοι και συνθεσεις για την αγωγη γαστρεντερικων διαταραχων |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
SPCG | Granted supplementary protection certificate |
Free format text: PRODUCT NAME: LINACLOTIDE; REG. NO/DATE: EU/1/12/801/001-004 20121126 Spc suppl protection certif: 2014013 Filing date: 20140521 Extension date: 20271128 |
|
MK1K | Patent expired |