NO20041368L - Azabicyklus-substituerte kondenserte heteroarylforbindelser for behandling av sykdom - Google Patents
Azabicyklus-substituerte kondenserte heteroarylforbindelser for behandling av sykdomInfo
- Publication number
- NO20041368L NO20041368L NO20041368A NO20041368A NO20041368L NO 20041368 L NO20041368 L NO 20041368L NO 20041368 A NO20041368 A NO 20041368A NO 20041368 A NO20041368 A NO 20041368A NO 20041368 L NO20041368 L NO 20041368L
- Authority
- NO
- Norway
- Prior art keywords
- azabicycle
- disease
- treatment
- heteroaryl compounds
- substituted condensed
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 125000001072 heteroaryl group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32656501P | 2001-10-02 | 2001-10-02 | |
US32662901P | 2001-10-02 | 2001-10-02 | |
US33488601P | 2001-11-15 | 2001-11-15 | |
US33963301P | 2001-12-12 | 2001-12-12 | |
PCT/US2002/029827 WO2003029252A1 (en) | 2001-10-02 | 2002-10-01 | Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20041368D0 NO20041368D0 (no) | 2004-04-01 |
NO20041368L true NO20041368L (no) | 2004-06-01 |
Family
ID=27502335
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20041368A NO20041368L (no) | 2001-10-02 | 2004-04-01 | Azabicyklus-substituerte kondenserte heteroarylforbindelser for behandling av sykdom |
Country Status (31)
Country | Link |
---|---|
US (3) | US6911543B2 (no) |
EP (1) | EP1432707B1 (no) |
JP (1) | JP4371811B2 (no) |
KR (1) | KR100614900B1 (no) |
AP (1) | AP1635A (no) |
AR (1) | AR037740A1 (no) |
AT (1) | ATE551340T1 (no) |
BG (1) | BG108650A (no) |
BR (1) | BR0213612A (no) |
CA (1) | CA2462453C (no) |
CO (1) | CO5570667A2 (no) |
CZ (1) | CZ2004408A3 (no) |
DK (1) | DK1432707T3 (no) |
EA (1) | EA007429B1 (no) |
ES (1) | ES2383001T3 (no) |
GE (1) | GEP20063814B (no) |
HR (1) | HRP20040259A2 (no) |
HU (1) | HUP0402289A2 (no) |
IL (1) | IL160884A0 (no) |
IS (1) | IS7188A (no) |
MA (1) | MA27138A1 (no) |
MX (1) | MXPA04003007A (no) |
MY (1) | MY138252A (no) |
NO (1) | NO20041368L (no) |
NZ (1) | NZ531786A (no) |
OA (1) | OA12708A (no) |
PL (1) | PL369895A1 (no) |
RS (1) | RS28004A (no) |
SK (1) | SK1562004A3 (no) |
TN (1) | TNSN04052A1 (no) |
WO (1) | WO2003029252A1 (no) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR036040A1 (es) * | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
EP1515967B1 (de) * | 2002-06-10 | 2006-11-02 | Bayer HealthCare AG | 2-heteroarylcarbonsäureamide |
WO2004013137A1 (en) * | 2002-08-01 | 2004-02-12 | Pharmacia & Upjohn Company Llc | 1h-pyrazole and 1h-pyrrole-azabicyclic compounds with alfa-7 nachr activity |
ES2405594T3 (es) | 2002-09-25 | 2013-05-31 | Memory Pharmaceuticals Corporation | Idazoles, benzotiazoles y benzisotiazoles, y preparación y usos de los mismos |
WO2004039815A2 (en) * | 2002-11-01 | 2004-05-13 | Pharmacia & Upjohn Company Llc | Compounds having both alpha7 nachr agonist and 5ht antagonist activity for treatment of cns diseases |
AU2003269413A1 (en) * | 2002-11-01 | 2004-05-25 | Pharmacia & Upjohn Company Llc | Nicotinic acetylcholine agonists in the treatment of glaucoma and retinal neuropathy |
EP1581223B2 (en) * | 2002-12-06 | 2016-05-25 | The Feinstein Institute for Medical Research | Inhibition of inflamation using alpha 7 receptor-binding cholinergic agonists |
US7238715B2 (en) * | 2002-12-06 | 2007-07-03 | The Feinstein Institute For Medical Research | Treatment of pancreatitis using alpha 7 receptor-binding cholinergic agonists |
AU2004303826A1 (en) | 2003-12-11 | 2005-07-07 | Aventis Pharmaceuticals Inc. | Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase I Epsilon |
JP4824578B2 (ja) | 2003-12-22 | 2011-11-30 | メモリー・ファーマシューティカルズ・コーポレイション | インドール類、1,2−ベンズイソオキサゾール類、および1,2−ベンゾイソチアゾール類、ならびにそれらの製造と使用 |
EP1699488A2 (en) * | 2003-12-23 | 2006-09-13 | Pfizer Products Incorporated | Therapeutic combination for cognition enhancement and psychotic disorders |
BRPI0508771A (pt) | 2004-03-25 | 2007-08-14 | Memory Pharm Corp | indazóis, benzotiazóis, benzoisotiazóis, benzisoxazóis, e a preparação e usos dos mesmos |
ATE487716T1 (de) * | 2004-04-22 | 2010-11-15 | Memory Pharm Corp | Indole, 1h-indazole, 1,2-benzisoxazole, 1,2- benzoisothiazole, deren herstellung und verwendungen |
WO2005107719A2 (en) * | 2004-05-06 | 2005-11-17 | Sandoz Ag | Pharmaceutical composition comprising hydrophobic drug having improved solubility |
US7632831B2 (en) * | 2004-05-07 | 2009-12-15 | Memory Pharmaceuticals Corporation | 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof |
AU2005319248A1 (en) * | 2004-12-22 | 2006-06-29 | Memory Pharmaceuticals Corporation | Nicotinic alpha-7 receptor ligands and preparation and uses thereof |
MX2007011436A (es) * | 2005-03-18 | 2007-10-12 | Abbott Lab | Ligando del receptor nicotinico neuronal 7 y composiciones antipsicoticas. |
FR2884822B1 (fr) * | 2005-04-22 | 2007-06-29 | Aventis Pharma Sa | Derives de triazines, leur preparation et leur application en therapeutique |
WO2007027855A2 (en) * | 2005-09-01 | 2007-03-08 | Array Biopharma Inc. | Raf inhibitor compounds and methods of use thereof |
US8106066B2 (en) * | 2005-09-23 | 2012-01-31 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof |
US8316104B2 (en) | 2005-11-15 | 2012-11-20 | California Institute Of Technology | Method and apparatus for collaborative system |
RU2010107462A (ru) * | 2007-08-02 | 2011-09-10 | Таргасепт, Инк. (Us) | ЛЕЧЕНИЕ α7-СЕЛЕКТИВНЫМИ ЛИГАНДАМИ |
US8697722B2 (en) * | 2007-11-02 | 2014-04-15 | Sri International | Nicotinic acetylcholine receptor modulators |
CA3017886A1 (en) | 2008-11-19 | 2010-05-27 | Envivo Pharmaceuticals, Inc. | Treatment of cognitive disorders with (r)-7-chloro-n-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide and pharmaceutically acceptable salts thereof |
TW201031664A (en) | 2009-01-26 | 2010-09-01 | Targacept Inc | Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide |
MX2011011972A (es) * | 2009-05-11 | 2011-12-08 | Envivo Pharmaceuticals Inc | Tratamiento de trastornos cognitivos con determinados receptores de acido nicotinico alfa-7 en combinacion con inhibidores de acetilcolinesterasa. |
WO2011022692A2 (en) * | 2009-08-20 | 2011-02-24 | University Of Tennessee Research Foundation, The | Furanopyridine cannabinoid compounds and related methods of use |
CN102905527B (zh) | 2010-01-11 | 2016-08-24 | 阿斯特来亚治疗有限责任公司 | 烟碱型乙酰胆碱受体调节剂 |
GB201002563D0 (en) | 2010-02-15 | 2010-03-31 | Cambridge Entpr Ltd | Compounds |
DK3029039T3 (en) | 2010-05-17 | 2017-12-04 | Forum Pharmaceuticals Inc | PHARMACEUTICAL FORMS CONTAINING CRYSTALLINIC FORMS OF (R) -7-CHLOR-N- (QUINUCLIDIN-3-YL) BENZO (B) THIOPHEN-2-CARBOXAMIDE HYDROCHLORIDE MONOHYDRATE |
WO2013002365A1 (ja) | 2011-06-30 | 2013-01-03 | 東レ株式会社 | 止痒剤 |
WO2013169646A1 (en) | 2012-05-08 | 2013-11-14 | Envivo Pharmaceuticals, Inc. | Methods of maintaining, treating or improving cognitive function |
MD20150071A2 (ro) | 2013-02-19 | 2016-02-29 | Pfizer Inc. | Compuşi azabenzimidazolici ca inhibitori ai PDE4 izoenzimelor pentru tratamentul tulburărilor SNC şi altor afecţiuni |
PL3102576T3 (pl) | 2014-02-03 | 2019-12-31 | Vitae Pharmaceuticals, Llc | Dihydropirolopirydynowe inhibitory ror-gamma |
JP6713982B2 (ja) | 2014-07-24 | 2020-06-24 | ファイザー・インク | ピラゾロピリミジン化合物 |
JP6506833B2 (ja) | 2014-08-06 | 2019-04-24 | ファイザー・インク | イミダゾピリダジン化合物 |
UA118989C2 (uk) | 2014-10-14 | 2019-04-10 | Вітае Фармасьютікалс, Інк. | Дигідропіролопіридинові інгібітори ror-гамма |
US9845308B2 (en) | 2014-11-05 | 2017-12-19 | Vitae Pharmaceuticals, Inc. | Isoindoline inhibitors of ROR-gamma |
US9663515B2 (en) | 2014-11-05 | 2017-05-30 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
JP6612874B2 (ja) | 2014-12-16 | 2019-11-27 | アクソファント サイエンシーズ ゲーエムベーハー | α7−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換キヌクリジンアミド化合物 |
RU2017145964A (ru) | 2015-06-10 | 2019-07-10 | Аксовант Сайенсиз Гмбх | Аминобензизоксазольные соединения в качестве агонистов α7-никотиновых ацетилхолиновых рецепторов |
WO2017024018A1 (en) | 2015-08-05 | 2017-02-09 | Vitae Pharmaceuticals, Inc. | Modulators of ror-gamma |
US10428062B2 (en) | 2015-08-12 | 2019-10-01 | Axovant Sciences Gmbh | Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors |
WO2017087608A1 (en) | 2015-11-20 | 2017-05-26 | Vitae Pharmaceuticals, Inc. | Modulators of ror-gamma |
TWI757266B (zh) | 2016-01-29 | 2022-03-11 | 美商維它藥物有限責任公司 | ROR-γ調節劑 |
KR20180110132A (ko) * | 2016-02-16 | 2018-10-08 | 반더빌트유니버시티 | 무스카린성 아세틸콜린 수용체 m1의 양성 알로스테릭 조절제 |
US9481674B1 (en) | 2016-06-10 | 2016-11-01 | Vitae Pharmaceuticals, Inc. | Dihydropyrrolopyridine inhibitors of ROR-gamma |
US10899759B2 (en) | 2016-09-30 | 2021-01-26 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor M1 |
IL298639A (en) | 2017-07-24 | 2023-01-01 | Vitae Pharmaceuticals Llc | Inhibitors of gamma ror |
WO2019018975A1 (en) | 2017-07-24 | 2019-01-31 | Vitae Pharmaceuticals, Inc. | INHIBITORS OF ROR GAMMA |
CN113825543A (zh) | 2019-03-19 | 2021-12-21 | 勃林格殷格翰动物保健美国公司 | 驱虫的氮杂-苯并噻吩和氮杂-苯并呋喃化合物 |
PE20231205A1 (es) | 2020-05-29 | 2023-08-17 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos heterociclicos como anthelminticos |
Family Cites Families (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ194747A (en) | 1979-08-29 | 1988-11-29 | Schering Ag | 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives |
US4612319A (en) | 1982-04-14 | 1986-09-16 | Beecham Group P.L.C. | Bridged quinolizidinylbenzamides, compositions containing them and methods for their use |
FI74707C (fi) | 1982-06-29 | 1988-03-10 | Sandoz Ag | Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror. |
CH664567A5 (de) | 1983-08-26 | 1988-03-15 | Sandoz Ag | Aromatische carbonsaeure- und sulfonsaeureester oder -amide. |
US4888353A (en) | 1986-02-28 | 1989-12-19 | Erbamont, Inc. | Carboxamides useful as antiemetic or antipsychotic agents |
US4605652A (en) | 1985-02-04 | 1986-08-12 | A. H. Robins Company, Inc. | Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes |
EP0201165B1 (en) | 1985-03-14 | 1994-07-20 | Beecham Group Plc | Medicaments for the treatment of emesis |
US4937247A (en) | 1985-04-27 | 1990-06-26 | Beecham Group P.L.C. | 1-acyl indazoles |
GB8520616D0 (en) | 1985-08-16 | 1985-09-25 | Beecham Group Plc | Compounds |
US4910193A (en) | 1985-12-16 | 1990-03-20 | Sandoz Ltd. | Treatment of gastrointestinal disorders |
EP0254584B1 (en) | 1986-07-25 | 1992-10-07 | Beecham Group Plc | Azabicyclic compounds, process for their preparation, and their pharmaceutical use |
HU895334D0 (en) | 1986-07-30 | 1990-01-28 | Sandoz Ag | Process for the preparation of nasal pharmaceutical compositions |
US4985437A (en) | 1986-12-17 | 1991-01-15 | Glaxo Group Limited | Medicaments |
EP0278173B1 (en) | 1986-12-17 | 1993-11-03 | Glaxo Group Limited | Use of heterocyclic derivatives in the treatment of depressions |
US5322951A (en) | 1987-01-05 | 1994-06-21 | Beecham Group, P.L.C. | Certain 1-(2,3-dihydro-indole)carbonyl intermediates |
GB8701022D0 (en) | 1987-01-19 | 1987-02-18 | Beecham Group Plc | Treatment |
US4835162A (en) | 1987-02-12 | 1989-05-30 | Abood Leo G | Agonists and antagonists to nicotine as smoking deterents |
DE3852145T2 (de) | 1987-02-18 | 1995-04-06 | Beecham Group Plc | Indolderivate, Verfahren zu deren Herstellung und pharmazeutische Präparate, die diese enthalten. |
EP0289170B1 (en) | 1987-04-25 | 1993-06-23 | Beecham Group Plc | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
DE3822792C2 (de) | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
US4921982A (en) | 1988-07-21 | 1990-05-01 | Eli Lilly And Company | 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists |
AU611976B2 (en) | 1987-12-24 | 1991-06-27 | John Wyeth & Brother Limited | Aroyl urea and carbamic acid derivatives of azabicyclo compounds |
DE3810552A1 (de) | 1988-03-29 | 1989-10-19 | Sandoz Ag | Ester und amide von indol-, benzo(b)thiopen-, benzo(b)furancarbonsaeuren oder 4-amino-2-methoxy-benzolsaeuren mit n-heterocyclischen oder n-heterobicyclischen alkoholen oder aminen, verfahren zu deren herstellung sie enthaltende pharmazeutische zusammensetzungen sowie applikator zur verabreichung derselben |
US4920219A (en) | 1988-11-29 | 1990-04-24 | Rorer Pharmaceutical Corp. | Substituted saturated and unsaturated indole quinoline and benzazepine carboxamides and their use as pharmacological agents |
WO1990014347A1 (en) | 1989-05-24 | 1990-11-29 | Nippon Shinyaku Co., Ltd. | Indole derivatives and medicine |
EP0402056A3 (en) | 1989-06-06 | 1991-09-04 | Beecham Group p.l.c. | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them |
US4935511A (en) | 1989-09-26 | 1990-06-19 | Rorer Pharmaceutical Corporation | Benzoxazine and benzoxazepine carboxamide 5-HT3 antagonists |
GB8928837D0 (en) | 1989-12-21 | 1990-02-28 | Beecham Group Plc | Pharmaceuticals |
GB9009542D0 (en) | 1990-04-27 | 1990-06-20 | Beecham Group Plc | Novel compounds |
CA2090037A1 (en) | 1990-08-31 | 1992-03-01 | Shoichi Chokai | Indole derivatives and drugs |
US5200415A (en) | 1990-11-01 | 1993-04-06 | Asahi Kasei Kogyo Kabushiki Kaisha | Pyrazolo[1,5-a]pyridine-3-carboxylic acid derivatives and their pharmaceutical use |
GB9027098D0 (en) | 1990-12-13 | 1991-02-06 | Beecham Group Plc | Pharmaceuticals |
HU211081B (en) | 1990-12-18 | 1995-10-30 | Sandoz Ag | Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same |
IL100432A (en) | 1990-12-27 | 1996-01-19 | Erba Carlo Spa | Dihydrobenzopuran carboxamides, their preparation and pharmaceutical preparations containing them |
GB9028105D0 (en) | 1990-12-27 | 1991-02-13 | Erba Carlo Spa | Process for the preparation of substituted benzofuran derivatives |
US5260303A (en) | 1991-03-07 | 1993-11-09 | G. D. Searle & Co. | Imidazopyridines as serotonergic 5-HT3 antagonists |
DE4115215A1 (de) | 1991-05-10 | 1992-11-12 | Merck Patent Gmbh | Indolderivate |
JP2553020B2 (ja) | 1991-11-07 | 1996-11-13 | 吉富製薬株式会社 | キヌクリジン化合物およびその医薬用途 |
JP2699794B2 (ja) | 1992-03-12 | 1998-01-19 | 三菱化学株式会社 | チエノ〔3,2−b〕ピリジン誘導体 |
WO1993021189A1 (en) | 1992-04-10 | 1993-10-28 | Asahi Kasei Kogyo Kabushiki Kaisha | Tetrahydropyridine derivative having substituents on three rings |
SE9201478D0 (sv) | 1992-05-11 | 1992-05-11 | Kabi Pharmacia Ab | Heteroaromatic quinuclidinenes, their use and preparation |
US5977144A (en) | 1992-08-31 | 1999-11-02 | University Of Florida | Methods of use and compositions for benzylidene- and cinnamylidene-anabaseines |
IT1265057B1 (it) | 1993-08-05 | 1996-10-28 | Dompe Spa | Tropil 7-azaindolil-3-carbossiamidi |
GB9406857D0 (en) | 1994-04-07 | 1994-06-01 | Sandoz Ltd | Improvements in or relating to organic compounds |
GB9507882D0 (en) | 1995-04-18 | 1995-05-31 | Pharmacia Spa | Substituted dihydrobenzofuran derivatives as 5-ht4 agonists |
SE9600683D0 (sv) | 1996-02-23 | 1996-02-23 | Astra Ab | Azabicyclic esters of carbamic acids useful in therapy |
ES2109190B1 (es) | 1996-03-22 | 1998-07-01 | Univ Madrid Complutense | Nuevos derivados de bencimidazol con afinidad por los receptores serotoninergicos 5-ht /5-ht |
CZ298824B6 (cs) | 1997-05-30 | 2008-02-20 | Neurosearch A/S | Deriváty 8-azabicyklo[3.2.1]okt-2-enu, zpusob jejich prípravy a jejich použití |
FR2769915B1 (fr) | 1997-10-21 | 2000-10-13 | Synthelabo | Derives d'indazole tricycliques, leur preparation et leur application en therapeutique |
ATE255888T1 (de) | 1998-06-01 | 2003-12-15 | Ortho Mcneil Pharm Inc | Tetrahydronaphtalene verbindungen und deren verwendung zur behandlung von neurodegenerativen krankheiten |
SE9900100D0 (sv) * | 1999-01-15 | 1999-01-15 | Astra Ab | New compounds |
JP2003501022A (ja) | 1999-05-27 | 2003-01-14 | ファルマシア・アンド・アップジョン・カンパニー | イオンチャネルコンダクタンスを測定するための方法およびその組成物 |
SE9904176D0 (sv) * | 1999-11-18 | 1999-11-18 | Astra Ab | New use |
TWI256314B (en) * | 2000-02-09 | 2006-06-11 | Mitsubishi Pharma Corp | Preventive-therapeutical medicament for gastroesophageal reflux disease |
SE0000540D0 (sv) | 2000-02-18 | 2000-02-18 | Astrazeneca Ab | New compounds |
US20010036943A1 (en) | 2000-04-07 | 2001-11-01 | Coe Jotham W. | Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines |
JP4616971B2 (ja) | 2000-07-18 | 2011-01-19 | 田辺三菱製薬株式会社 | 1−アザビシクロアルカン化合物およびその医薬用途 |
US20020016334A1 (en) | 2000-07-31 | 2002-02-07 | Coe Jotham Wadsworth | Pharmaceutical composition for the treatment of attention deficit hyperactivity disorder (ADHD) |
JP2004506735A (ja) | 2000-08-18 | 2004-03-04 | ファルマシア・アンド・アップジョン・カンパニー | 疾患治療用キヌクリジン置換アリール化合物 |
AU2001284646A1 (en) * | 2000-08-21 | 2002-03-04 | Pharmacia And Upjohn Company | Quinuclidine-substituted heteroaryl moieties for treatment of disease |
AR036040A1 (es) * | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
DE10211415A1 (de) | 2002-03-15 | 2003-09-25 | Bayer Ag | Bicyclische N-Biarylamide |
CA2482312A1 (en) | 2002-04-18 | 2003-10-23 | Astrazeneca Ab | Thienyl compounds |
AU2003225456B2 (en) | 2002-04-18 | 2009-02-05 | Astrazeneca Ab | Furyl compounds |
EP1499616B1 (en) | 2002-04-18 | 2009-06-17 | AstraZeneca AB | Heterocyclic compounds |
-
2002
- 2002-10-01 US US10/262,257 patent/US6911543B2/en not_active Expired - Fee Related
- 2002-10-01 EP EP02778286A patent/EP1432707B1/en not_active Expired - Lifetime
- 2002-10-01 AT AT02778286T patent/ATE551340T1/de active
- 2002-10-01 HU HU0402289A patent/HUP0402289A2/hu unknown
- 2002-10-01 NZ NZ531786A patent/NZ531786A/en unknown
- 2002-10-01 WO PCT/US2002/029827 patent/WO2003029252A1/en active Application Filing
- 2002-10-01 IL IL16088402A patent/IL160884A0/xx unknown
- 2002-10-01 MX MXPA04003007A patent/MXPA04003007A/es unknown
- 2002-10-01 CZ CZ2004408A patent/CZ2004408A3/cs unknown
- 2002-10-01 ES ES02778286T patent/ES2383001T3/es not_active Expired - Lifetime
- 2002-10-01 EA EA200400387A patent/EA007429B1/ru unknown
- 2002-10-01 RS YUP-280/04A patent/RS28004A/sr unknown
- 2002-10-01 JP JP2003532500A patent/JP4371811B2/ja not_active Expired - Fee Related
- 2002-10-01 KR KR1020047004871A patent/KR100614900B1/ko not_active IP Right Cessation
- 2002-10-01 SK SK156-2004A patent/SK1562004A3/sk unknown
- 2002-10-01 CA CA002462453A patent/CA2462453C/en not_active Expired - Fee Related
- 2002-10-01 GE GE5551A patent/GEP20063814B/en unknown
- 2002-10-01 PL PL02369895A patent/PL369895A1/xx not_active Application Discontinuation
- 2002-10-01 DK DK02778286.1T patent/DK1432707T3/da active
- 2002-10-01 OA OA1200400087A patent/OA12708A/en unknown
- 2002-10-01 BR BR0213612-0A patent/BR0213612A/pt not_active IP Right Cessation
- 2002-10-01 AP APAP/P/2004/003002A patent/AP1635A/en active
- 2002-10-02 MY MYPI20023689A patent/MY138252A/en unknown
- 2002-10-02 AR ARP020103718A patent/AR037740A1/es unknown
-
2004
- 2004-03-17 HR HR20040259A patent/HRP20040259A2/hr not_active Application Discontinuation
- 2004-03-18 IS IS7188A patent/IS7188A/is unknown
- 2004-03-24 BG BG108650A patent/BG108650A/xx unknown
- 2004-03-30 CO CO04030193A patent/CO5570667A2/es not_active Application Discontinuation
- 2004-04-01 NO NO20041368A patent/NO20041368L/no not_active Application Discontinuation
- 2004-04-01 MA MA27603A patent/MA27138A1/fr unknown
- 2004-04-01 TN TNP2004000052A patent/TNSN04052A1/fr unknown
-
2005
- 2005-05-26 US US11/137,912 patent/US20050222196A1/en not_active Abandoned
- 2005-05-26 US US11/139,066 patent/US20050234092A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20041368D0 (no) | Azabicyklus-substituerte kondenserte heteroarylforbindelser for behandling av sykdom | |
NO20035522D0 (no) | Kinuklidin-substituerte multisykliske heteroaryler for behandling av sykdom | |
NO20042680L (no) | Fremgangsmater for fremstilling av O-demetylvenflaxine | |
NO20052580D0 (no) | Blandinger for behandling av infeksjon av Flavivirida viruser | |
EE200200716A (et) | Ühendid Alzheimeri tõve käitluseks | |
NO20021474D0 (no) | Forbindelser for behandling av ischemi | |
NO20031443D0 (no) | Forbindelser nyttige for behandling av inflammatoriske sykdommer | |
NO20040027L (no) | Fremgangsmate for fremstillingen av escitalopram | |
NO20033205D0 (no) | Terapeutiske kromanforbindelser | |
NO20033803D0 (no) | Karbamat for behandling av bevegelseslidelser | |
NO20033433D0 (no) | Fremgangsmåte for fremstilling av 2-(2-pyridylmetyl)sulfinyl- 1H-benzimidasol | |
NO20033804D0 (no) | Karbamatforbindelser for behandling av smerte | |
IS7163A (is) | Aðferðir til meðhöndlunar á lungnasjúkdómi | |
FI20011889A0 (fi) | Menetelmä ksylitolin valmistamiseksi | |
NO20034003D0 (no) | Fremgangsmåte for fremstilling av imidazol-forbindelser | |
NO20035538D0 (no) | Fremgangsmåte for fremstilling av zaleplon | |
NO20042640L (no) | Fremgangsmate for fremstilling av ekinocandinderivater | |
NO20042613L (no) | Ny anvendelse for behandling av gastroosofagial refluks | |
NO20042476L (no) | Anvendelse av desoxypeganin for behandling av klinisk depresjon | |
NO20042214L (no) | Aryl kondenserte azaplycykliske forbindelser | |
NO20012612L (no) | Isonipecotamider for behandlingen av integrin-formidlede sykdommer | |
NO20033290L (no) | Pyrrolderivater for behandling av cytokinformidlede sykdommer | |
NO20042166L (no) | Kombinasjonsterapi for behandling av sykdom | |
NO20041193L (no) | Fremgangsmåte til fremstilling av beta-ionylidenacetaldehyd | |
DK1401455T3 (da) | Anvendelse af phosphatadsorbent til behandling af karsygdomme |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |