NO20035399L - Pyrrolidinoksadiazol- og tiadiazolderivater - Google Patents

Pyrrolidinoksadiazol- og tiadiazolderivater

Info

Publication number: NO20035399L
Authority: NO; Norway
Prior art keywords: thiadiazole derivatives; pyrrolidine oxadiazole; oxadiazole; pyrrolidine; thiadiazole
Prior art date: 2001-06-18

Application number

NO20035399A

Other languages

English (en)

Other versions

NO20035399D0 (no

Inventor

Matthias Schwarz

Russel J Thomas

Anna Quattorpani

Patrick Page

Vincent Pomel

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-18

Filing date

2003-12-04

Publication date

2004-02-17

2003-12-04 Application filed by Applied Research Systems filed Critical Applied Research Systems

2003-12-04 Publication of NO20035399D0 publication Critical patent/NO20035399D0/no

2004-02-17 Publication of NO20035399L publication Critical patent/NO20035399L/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

NO20035399A 2001-06-18 2003-12-04 Pyrrolidinoksadiazol- og tiadiazolderivater NO20035399L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01113632		2001-06-18
PCT/EP2002/006629 WO2002102799A2 (en)	2001-06-18	2002-06-14	Pyrrolidine oxadiazole- and thiadiazole oxime derivatives being oxytocin receptor antagonists

Publications (2)

Publication Number	Publication Date
NO20035399D0 NO20035399D0 (no)	2003-12-04
NO20035399L true NO20035399L (no)	2004-02-17

Family

ID=8177641

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20035399A NO20035399L (no)	2001-06-18	2003-12-04	Pyrrolidinoksadiazol- og tiadiazolderivater

Country Status (27)

Country	Link
US (2)	US7115639B2 (no)
EP (1)	EP1444225B1 (no)
JP (1)	JP4426284B2 (no)
KR (1)	KR20040030678A (no)
CN (1)	CN100564378C (no)
AR (1)	AR036108A1 (no)
AU (1)	AU2002319237B2 (no)
BG (1)	BG108424A (no)
BR (1)	BR0211030A (no)
CA (1)	CA2449578C (no)
CZ (1)	CZ20033475A3 (no)
EA (1)	EA006212B1 (no)
EE (1)	EE200400022A (no)
ES (1)	ES2397305T3 (no)
HK (1)	HK1074204A1 (no)
HR (1)	HRP20031017A2 (no)
HU (1)	HUP0400238A2 (no)
IL (1)	IL159219A0 (no)
MX (1)	MXPA03011441A (no)
MY (1)	MY128890A (no)
NO (1)	NO20035399L (no)
PL (1)	PL367275A1 (no)
RS (1)	RS99503A (no)
SK (1)	SK15552003A3 (no)
UA (1)	UA75145C2 (no)
WO (1)	WO2002102799A2 (no)
ZA (1)	ZA200309402B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20040030678A (ko)	2001-06-18	2004-04-09	어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이.	피롤리딘 옥사디아졸 및 티아디아졸 유도체
US7557136B2 (en) *	2003-02-27	2009-07-07	Laboratoires Serono Sa	Pyrrolidine derivatives as oxytocin antagonists
EP1725526B1 (en) *	2004-02-26	2007-12-12	Laboratoires Serono SA	Method for preparing pyrrolidine oximes
KR101562549B1 (ko)	2005-05-10	2015-10-23	인사이트 홀딩스 코포레이션	인돌아민 2,3-디옥시게나제의 조절제 및 이의 사용방법
TWI382974B (zh)	2005-12-20	2013-01-21	Incyte Corp	作為吲哚胺２，３-二氧化酶調節劑之ｎ-羥基甲脒基雜環化物
US20080125470A1 (en)	2006-09-19	2008-05-29	Incyte Corporation	N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
CL2007002650A1 (es)	2006-09-19	2008-02-08	Incyte Corp	Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
PE20110308A1 (es)	2008-07-08	2011-06-10	Incyte Corp	1,2,5-oxadiazoles como inhibidores de indolamina 2,3-dioxigenasa
EP2845850A1 (en)	2013-09-10	2015-03-11	ObsEva S.A.	Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists
EP3066085B1 (en)	2013-11-08	2020-05-13	Incyte Holdings Corporation	Process for the synthesis of an indoleamine 2,3-dioxygenase inhibitor
EP2886107A1 (en)	2013-12-17	2015-06-24	ObsEva S.A.	Oral formulations of pyrrolydine derivatives
CN114105850A (zh)	2014-07-02	2022-03-01	奥布赛瓦股份公司	治疗ot-r活性相关的病症的方法中可用的晶体

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2722190B1 (fr)	1994-07-05	1996-10-04	Sanofi Sa	Derives de 1-benzyl-1,3-dihydro-2h-benzimidazol-2-one, leur preparation, les compositions pharmaceutique en contenant
AU4763896A (en)	1995-01-24	1996-08-14	Merck & Co., Inc.	Tocolytic oxytocin receptor antagonists
US5756497A (en)	1996-03-01	1998-05-26	Merck & Co., Inc.	Tocolytic oxytocin receptor antagonists
FR2757157B1 (fr)	1996-12-13	1999-12-31	Sanofi Sa	Derives d'indolin-2-one, procede pour leur preparation et compositions pharmaceutiques les contenant
JP2002543129A (ja)	1999-05-05	2002-12-17	メルクエンドカムパニーインコーポレーテッド	抗微生物剤としての新規なプロリン類
WO2001074769A1 (en) *	2000-03-27	2001-10-11	Applied Research Systems Ars Holding N.V.	Pharmaceutically active pyrrolidine derivatives as bax inhibitors
AU2001256209B2 (en) *	2000-03-27	2006-02-16	Merck Serono Sa	Pharmaceutically active pyrrolidine derivatives
AU1401902A (en) *	2000-10-17	2002-04-29	Applied Research Systems	Pharmaceutically active sulfanilide derivatives
ATE394371T1 (de) *	2001-03-20	2008-05-15	Serono Lab	Pyrrolidinesterderivate mit oxytocinmodulierender wirkung
KR20040030678A (ko)	2001-06-18	2004-04-09	어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이.	피롤리딘 옥사디아졸 및 티아디아졸 유도체
WO2003053437A1 (en) *	2001-12-20	2003-07-03	Applied Research Systems Ars Holding N.V.	Triazoles as oxytocin antagonists
UA78058C2 (en) *	2002-07-05	2007-02-15	Applied Research Systems	Pyrrolidine derivative as oxitocin antagonists

2002
- 2002-06-14 KR KR10-2003-7016485A patent/KR20040030678A/ko not_active Application Discontinuation
- 2002-06-14 CN CNB028159446A patent/CN100564378C/zh not_active Expired - Fee Related
- 2002-06-14 IL IL15921902A patent/IL159219A0/xx unknown
- 2002-06-14 UA UA20031211897A patent/UA75145C2/uk unknown
- 2002-06-14 WO PCT/EP2002/006629 patent/WO2002102799A2/en not_active Application Discontinuation
- 2002-06-14 RS YU99503A patent/RS99503A/sr unknown
- 2002-06-14 HU HU0400238A patent/HUP0400238A2/hu unknown
- 2002-06-14 MX MXPA03011441A patent/MXPA03011441A/es active IP Right Grant
- 2002-06-14 US US10/480,992 patent/US7115639B2/en not_active Expired - Fee Related
- 2002-06-14 SK SK1555-2003A patent/SK15552003A3/sk not_active Application Discontinuation
- 2002-06-14 JP JP2003506272A patent/JP4426284B2/ja not_active Expired - Fee Related
- 2002-06-14 BR BR0211030-0A patent/BR0211030A/pt not_active IP Right Cessation
- 2002-06-14 EP EP02748785A patent/EP1444225B1/en not_active Expired - Lifetime
- 2002-06-14 EE EEP200400022A patent/EE200400022A/xx unknown
- 2002-06-14 PL PL02367275A patent/PL367275A1/xx not_active Application Discontinuation
- 2002-06-14 CZ CZ20033475A patent/CZ20033475A3/cs unknown
- 2002-06-14 AU AU2002319237A patent/AU2002319237B2/en not_active Ceased
- 2002-06-14 CA CA2449578A patent/CA2449578C/en not_active Expired - Fee Related
- 2002-06-14 ES ES02748785T patent/ES2397305T3/es not_active Expired - Lifetime
- 2002-06-14 EA EA200400049A patent/EA006212B1/ru not_active IP Right Cessation
- 2002-06-18 MY MYPI20022260A patent/MY128890A/en unknown
- 2002-06-21 AR ARP020102353A patent/AR036108A1/es unknown
2003
- 2003-12-03 ZA ZA200309402A patent/ZA200309402B/en unknown
- 2003-12-04 NO NO20035399A patent/NO20035399L/no unknown
- 2003-12-08 HR HR20031017A patent/HRP20031017A2/xx not_active Application Discontinuation
- 2003-12-08 BG BG108424A patent/BG108424A/xx unknown
2005
- 2005-09-16 HK HK05108106.9A patent/HK1074204A1/xx not_active IP Right Cessation
2006
- 2006-06-09 US US11/449,802 patent/US20060229343A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1444225B1 (en)	2012-10-10
EA200400049A1 (ru)	2004-08-26
EE200400022A (et)	2004-04-15
JP4426284B2 (ja)	2010-03-03
NO20035399D0 (no)	2003-12-04
HUP0400238A2 (hu)	2004-07-28
MY128890A (en)	2007-02-28
JP2004534804A (ja)	2004-11-18
KR20040030678A (ko)	2004-04-09
CA2449578A1 (en)	2002-12-27
US7115639B2 (en)	2006-10-03
ZA200309402B (en)	2004-12-03
CA2449578C (en)	2011-12-13
US20060229343A1 (en)	2006-10-12
AR036108A1 (es)	2004-08-11
SK15552003A3 (sk)	2004-05-04
BG108424A (en)	2005-03-31
WO2002102799A2 (en)	2002-12-27
BR0211030A (pt)	2004-06-22
CZ20033475A3 (en)	2004-05-12
WO2002102799A3 (en)	2003-04-03
UA75145C2 (en)	2006-03-15
MXPA03011441A (es)	2004-07-01
HRP20031017A2 (en)	2004-04-30
ES2397305T3 (es)	2013-03-06
EP1444225A2 (en)	2004-08-11
AU2002319237B2 (en)	2008-01-03
RS99503A (en)	2006-12-15
PL367275A1 (en)	2005-02-21
CN1639155A (zh)	2005-07-13
HK1074204A1 (en)	2005-11-04
IL159219A0 (en)	2004-06-01
CN100564378C (zh)	2009-12-02
US20040220238A1 (en)	2004-11-04
EA006212B1 (ru)	2005-10-27

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