NO20025720L - Nye forbindelser med antibakteriell, soppdrepende eller antitumoraktivitet - Google Patents

Nye forbindelser med antibakteriell, soppdrepende eller antitumoraktivitet

Info

Publication number
NO20025720L
NO20025720L NO20025720A NO20025720A NO20025720L NO 20025720 L NO20025720 L NO 20025720L NO 20025720 A NO20025720 A NO 20025720A NO 20025720 A NO20025720 A NO 20025720A NO 20025720 L NO20025720 L NO 20025720L
Authority
NO
Norway
Prior art keywords
antifungal
antibacterial
antitumor activity
new compounds
antitumor
Prior art date
Application number
NO20025720A
Other languages
English (en)
Other versions
NO20025720D0 (no
Inventor
Wentao Zhang
Sebastian Johannes R Liehr
Mark Douglas Velligan
Natalia B Dyatkina
Janos Botyanszki
Dong-Fang Shi
Christopher Don Roberts
Alexander Khorlin
Peter Harold Nelson
Joseph Martin Muchowski
Original Assignee
Genelabs Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genelabs Tech Inc filed Critical Genelabs Tech Inc
Publication of NO20025720D0 publication Critical patent/NO20025720D0/no
Publication of NO20025720L publication Critical patent/NO20025720L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
NO20025720A 2000-06-27 2002-11-28 Nye forbindelser med antibakteriell, soppdrepende eller antitumoraktivitet NO20025720L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21447800P 2000-06-27 2000-06-27
PCT/US2001/020334 WO2002000650A2 (en) 2000-06-27 2001-06-26 Novel compounds possessing antibacterial, antifungal or antitumor activity

Publications (2)

Publication Number Publication Date
NO20025720D0 NO20025720D0 (no) 2002-11-28
NO20025720L true NO20025720L (no) 2003-02-26

Family

ID=22799223

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20025720A NO20025720L (no) 2000-06-27 2002-11-28 Nye forbindelser med antibakteriell, soppdrepende eller antitumoraktivitet

Country Status (15)

Country Link
US (2) US6849713B2 (no)
EP (1) EP1294713A2 (no)
JP (1) JP2004501915A (no)
KR (1) KR20030011371A (no)
CN (1) CN1439006A (no)
AU (1) AU2001270183A1 (no)
BR (1) BR0112030A (no)
CA (1) CA2414512A1 (no)
IL (1) IL153119A0 (no)
MX (1) MXPA02012271A (no)
NO (1) NO20025720L (no)
NZ (1) NZ522839A (no)
RU (1) RU2003101969A (no)
WO (1) WO2002000650A2 (no)
ZA (1) ZA200209774B (no)

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AU2003275225A1 (en) * 2002-09-20 2004-04-08 Genelabs Technologies, Inc. Novel aromatic compounds possessing antifungal or antibacterial activity
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JP2006509027A (ja) 2002-12-10 2006-03-16 オーシェント ファーマシューティカルズ コーポレーション (ピロールカルボキサミド)−(ベンズアミド)−(イミダゾールカルボキサミド)モチーフを有する抗菌化合物
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WO2004099155A2 (en) * 2003-05-02 2004-11-18 Elan Pharmaceuticals, Inc. 4-bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carboxylic acid (phenyl) amide derivates and related compounds as bradykinin b1 receptor antagonists for the treatment of inflamatory diseases
CA2524269A1 (en) * 2003-05-02 2004-11-18 Elan Pharmaceuticals, Inc. 4- bromo - 5 - (2- chloro - benzoylamino) - 1h - pyrazole - 3 - carboxylic acid amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases
US9512125B2 (en) * 2004-11-19 2016-12-06 The Regents Of The University Of California Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
CA2647391C (en) * 2006-04-04 2015-12-29 The Regents Of The University Of California Kinase antagonists
KR101104666B1 (ko) * 2006-09-06 2012-01-13 에프. 호프만-라 로슈 아게 단백질 키나제 억제제로서의 헤테로아릴 유도체
GB0619325D0 (en) 2006-09-30 2006-11-08 Univ Strathclyde New compounds
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US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
MX2010007419A (es) 2008-01-04 2010-11-12 Intellikine Inc Ciertas entidades quimicas, composiciones y metodos.
EP2252293B1 (en) * 2008-03-14 2018-06-27 Intellikine, LLC Kinase inhibitors and methods of use
US8993580B2 (en) * 2008-03-14 2015-03-31 Intellikine Llc Benzothiazole kinase inhibitors and methods of use
WO2010006072A2 (en) 2008-07-08 2010-01-14 The Regents Of The University Of California Mtor modulators and uses thereof
CN102124009B (zh) * 2008-07-08 2014-07-23 因特利凯公司 激酶抑制剂及其使用方法
US8273900B2 (en) 2008-08-07 2012-09-25 Novartis Ag Organic compounds
US8703778B2 (en) 2008-09-26 2014-04-22 Intellikine Llc Heterocyclic kinase inhibitors
DK2358720T3 (en) 2008-10-16 2016-06-06 Univ California Heteroarylkinaseinhibitorer fused-ring
US8476282B2 (en) * 2008-11-03 2013-07-02 Intellikine Llc Benzoxazole kinase inhibitors and methods of use
JP5789252B2 (ja) 2009-05-07 2015-10-07 インテリカイン, エルエルシー 複素環式化合物およびその使用
US8980899B2 (en) 2009-10-16 2015-03-17 The Regents Of The University Of California Methods of inhibiting Ire1
US8604032B2 (en) 2010-05-21 2013-12-10 Infinity Pharmaceuticals, Inc. Chemical compounds, compositions and methods for kinase modulation
EP2637669A4 (en) 2010-11-10 2014-04-02 Infinity Pharmaceuticals Inc Heterocyclic compounds and their use
JP2014501790A (ja) 2011-01-10 2014-01-23 インフィニティー ファーマシューティカルズ, インコーポレイテッド イソキノリノンの調製方法及びイソキノリノンの固体形態
TWI592411B (zh) 2011-02-23 2017-07-21 英特爾立秦有限責任公司 激酶抑制劑之組合及其用途
CN103930422A (zh) 2011-07-19 2014-07-16 无限药品股份有限公司 杂环化合物及其用途
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CN102952062B (zh) * 2011-08-12 2016-06-08 中国医学科学院医药生物技术研究所 取代苯并杂环类化合物及其制备方法和应用
KR20140075693A (ko) 2011-08-29 2014-06-19 인피니티 파마슈티칼스, 인코포레이티드 헤테로사이클릭 화합물 및 그의 용도
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WO2015051241A1 (en) 2013-10-04 2015-04-09 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
DK3119397T3 (da) 2014-03-19 2022-03-28 Infinity Pharmaceuticals Inc Heterocykliske forbindelser til anvendelse i behandling af PI3K-gamma-medierede lidelser
US20150320755A1 (en) 2014-04-16 2015-11-12 Infinity Pharmaceuticals, Inc. Combination therapies
US9708348B2 (en) 2014-10-03 2017-07-18 Infinity Pharmaceuticals, Inc. Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof
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Also Published As

Publication number Publication date
WO2002000650A2 (en) 2002-01-03
NO20025720D0 (no) 2002-11-28
BR0112030A (pt) 2003-04-29
JP2004501915A (ja) 2004-01-22
EP1294713A2 (en) 2003-03-26
IL153119A0 (en) 2003-06-24
CN1439006A (zh) 2003-08-27
MXPA02012271A (es) 2004-09-06
CA2414512A1 (en) 2002-01-03
US6849713B2 (en) 2005-02-01
US20020037856A1 (en) 2002-03-28
RU2003101969A (ru) 2004-07-10
US6906103B2 (en) 2005-06-14
WO2002000650A3 (en) 2002-10-24
AU2001270183A1 (en) 2002-01-08
ZA200209774B (en) 2004-03-02
KR20030011371A (ko) 2003-02-07
US20030119749A1 (en) 2003-06-26
NZ522839A (en) 2004-11-26
WO2002000650A9 (en) 2003-03-06

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