NO20024276L - TIR smaksreseptorer samt gener som koder for disse - Google Patents

TIR smaksreseptorer samt gener som koder for disse

Info

Publication number
NO20024276L
NO20024276L NO20024276A NO20024276A NO20024276L NO 20024276 L NO20024276 L NO 20024276L NO 20024276 A NO20024276 A NO 20024276A NO 20024276 A NO20024276 A NO 20024276A NO 20024276 L NO20024276 L NO 20024276L
Authority
NO
Norway
Prior art keywords
methods
genes
receptors
taste
mammal
Prior art date
Application number
NO20024276A
Other languages
English (en)
Other versions
NO20024276D0 (no
Inventor
Jon Elliot Adler
Sergey Zozulya
Shawn M O'connel
Xiaocong Li
Lena Staszewski
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of NO20024276D0 publication Critical patent/NO20024276D0/no
Publication of NO20024276L publication Critical patent/NO20024276L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Confectionery (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
NO20024276A 2000-03-07 2002-09-06 TIR smaksreseptorer samt gener som koder for disse NO20024276L (no)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US18754600P 2000-03-07 2000-03-07
US19553600P 2000-04-07 2000-04-07
US20984000P 2000-06-06 2000-06-06
US21421300P 2000-06-23 2000-06-23
US22644800P 2000-08-17 2000-08-17
US25922701P 2001-01-03 2001-01-03
PCT/US2001/007265 WO2001066563A2 (en) 2000-03-07 2001-03-07 T1r taste receptors and genes encoding same

Publications (2)

Publication Number Publication Date
NO20024276D0 NO20024276D0 (no) 2002-09-06
NO20024276L true NO20024276L (no) 2002-11-06

Family

ID=27558784

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20024276A NO20024276L (no) 2000-03-07 2002-09-06 TIR smaksreseptorer samt gener som koder for disse

Country Status (16)

Country Link
US (25) US7244835B2 (no)
EP (4) EP2143732B1 (no)
JP (2) JP5403842B2 (no)
CN (3) CN1543474A (no)
AT (2) ATE456577T1 (no)
AU (2) AU4008601A (no)
CA (1) CA2402214C (no)
DE (3) DE01914732T1 (no)
DK (3) DK1944319T3 (no)
ES (3) ES2311508T3 (no)
HK (1) HK1139965A1 (no)
IL (1) IL151578A0 (no)
MX (1) MXPA02008724A (no)
NO (1) NO20024276L (no)
TW (1) TW201006846A (no)
WO (1) WO2001066563A2 (no)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
US6383778B1 (en) 1998-07-28 2002-05-07 The Regents Of The University Of California Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
TW201006846A (en) * 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
AU2001255681A1 (en) * 2000-04-28 2001-11-12 The Monell Chemical Senses Center Gene and sequence variation associated with sensing carbohydrate compounds and other sweeteners
GB2364058A (en) * 2000-05-05 2002-01-16 Smithkline Beecham Corp AXOR79, a G-protein coupled receptor
WO2001090359A2 (en) * 2000-05-22 2001-11-29 Incyte Genomics, Inc. G-protein coupled receptors
JP2004513614A (ja) * 2000-06-16 2004-05-13 インサイト・ゲノミックス・インコーポレイテッド Ｇタンパク質結合受容体
AU2001295578A1 (en) * 2000-09-25 2002-04-02 Bayer Aktiengesellschaft Regulation of human g protein-coupled receptor
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US20080244761A1 (en) * 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7309577B2 (en) * 2001-03-07 2007-12-18 Senomyx, Inc. Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
US6955887B2 (en) 2001-03-30 2005-10-18 Senomyx, Inc. Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US7763431B1 (en) 2001-03-07 2010-07-27 Senomyx, Inc. Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
IL158488A0 (en) * 2001-04-20 2004-05-12 Sinai School Medicine Tir3 a novel taste receptor
WO2003001876A2 (en) * 2001-06-26 2003-01-09 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
JP2005505262A (ja) 2001-07-03 2005-02-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 哺乳動物の甘味およびアミノ酸のヘテロダイマー性の味覚レセプター
US20040029789A1 (en) * 2001-07-05 2004-02-12 Anderson David W. Novel proteins and nucleic acids encoding same
US7314725B2 (en) 2001-07-20 2008-01-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Phenylthiocarbamide (PTC) taste receptor
WO2003025137A2 (en) * 2001-09-18 2003-03-27 Irm, Llc Sweet taste receptors
EP1507801A1 (en) * 2002-05-20 2005-02-23 TVD Taste Virtual Dimensions, Inc. Antibodies and their use for the modulation of taste sensation
AU2004258071A1 (en) 2003-06-19 2005-01-27 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Variants of human taste receptor genes
CN103275058B (zh) * 2003-08-06 2016-02-24 西诺米克斯公司 调味剂、味道调节剂、促味剂、味觉增强剂、鲜味剂或甜味剂和/或增强剂及其用途
US20050244810A1 (en) * 2003-09-29 2005-11-03 Egan Josephine M Taste signaling in gastrointestinal cells
US20050106571A1 (en) 2003-10-02 2005-05-19 The Regents Of The University Of California Mammalian T1R3 sweet taste receptors
US20060045953A1 (en) * 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
WO2006068745A1 (en) 2004-12-22 2006-06-29 Cargill, Incorporated Methods for determining cellular response to stimuli
WO2006084184A2 (en) * 2005-02-04 2006-08-10 Senomyx, Inc. Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
JP4734346B2 (ja) 2005-02-04 2011-07-27 セノミックス インコーポレイテッド 連結ヘテロアリール部分を含む化合物、ならびに食用組成物のための新規なうまみフレーバー改変剤、味物質および味覚増強剤としての使用
WO2006113422A2 (en) 2005-04-13 2006-10-26 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Services Human sweet and umami taste receptor variants
CN101179943B (zh) 2005-05-23 2013-06-26 卡夫食品环球品牌有限责任公司 填充液体的咀嚼型胶基糖组合物
WO2006127935A1 (en) 2005-05-23 2006-11-30 Cadbury Adams Usa Llc Taste potentiator compositions and beverages containing same
US7851005B2 (en) 2005-05-23 2010-12-14 Cadbury Adams Usa Llc Taste potentiator compositions and beverages containing same
US7851006B2 (en) 2005-05-23 2010-12-14 Cadbury Adams Usa Llc Taste potentiator compositions and beverages containing same
AR055329A1 (es) * 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
US20110097741A1 (en) * 2006-04-20 2011-04-28 Jay Patrick Slack Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays
EP3235811B1 (en) 2006-04-21 2018-07-25 Senomyx, Inc. Process of preparing oxalamides
EP2015638A4 (en) * 2006-04-28 2010-09-29 Redpoint Bio Corp TRIARYL-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE AS TASTE INHIBITORS
WO2008008224A2 (en) * 2006-07-10 2008-01-17 Duke University Sour taste receptor compositions and methods
EP2087358A2 (en) * 2006-11-15 2009-08-12 Redpoint Bio Corporation Spicematrix technology for taste compound identification
US9603848B2 (en) * 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
US8633186B2 (en) 2007-06-08 2014-01-21 Senomyx Inc. Modulation of chemosensory receptors and ligands associated therewith
US7928111B2 (en) * 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
GB0713297D0 (en) 2007-07-10 2007-08-15 Cadbury Schweppes Plc Chocolate compositions having improved flavour characteristics
US9714941B2 (en) * 2007-07-31 2017-07-25 Massachusetts Institute Of Technology Bio-sensing nanodevice
US8609173B2 (en) 2008-07-31 2013-12-17 Senomyx Inc. Compositions comprising sweetness enhancers and methods of making them
WO2010014903A1 (en) 2008-07-31 2010-02-04 Massachusetts Institute Of Technology Multiplexed olfactory receptor-based microsurface plasmon polariton detector
MY153622A (en) 2008-07-31 2015-02-27 Senomyx Inc Processes and intermediates for making sweet taste enhancers
US20120184465A1 (en) * 2009-07-20 2012-07-19 Verdezyne, Inc. Combinatorial methods for optimizing engineered microorganism function
JP2013512664A (ja) 2009-12-02 2013-04-18 ユニリーバー・ナームローゼ・ベンノートシヤープ 味覚受容体の潜在的モジュレーター化合物をスクリーニングする改善された方法
RU2576451C2 (ru) 2010-08-12 2016-03-10 Синомикс, Инк. Способ улучшения стабильности усилителей сладкого вкуса и композиция, содержащая стабилизированный усилитель сладкого вкуса
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
PL2701532T3 (pl) 2011-04-29 2018-04-30 Intercontinental Great Brands Llc Enkapsulowany kwas, sposób jego przygotowania oraz zawierająca go guma do żucia
EP2742350B1 (en) 2011-08-08 2019-10-30 The Coca-Cola Company Cell lines comprising endogenous taste receptors and their uses
US9254099B2 (en) 2013-05-23 2016-02-09 Medibotics Llc Smart watch and food-imaging member for monitoring food consumption
US9456916B2 (en) 2013-03-12 2016-10-04 Medibotics Llc Device for selectively reducing absorption of unhealthy food
US9042596B2 (en) 2012-06-14 2015-05-26 Medibotics Llc Willpower watch (TM)—a wearable food consumption monitor
US9536449B2 (en) 2013-05-23 2017-01-03 Medibotics Llc Smart watch and food utensil for monitoring food consumption
US10314492B2 (en) 2013-05-23 2019-06-11 Medibotics Llc Wearable spectroscopic sensor to measure food consumption based on interaction between light and the human body
US9442100B2 (en) 2013-12-18 2016-09-13 Medibotics Llc Caloric intake measuring system using spectroscopic and 3D imaging analysis
AU2013299859B2 (en) 2012-08-06 2017-06-15 Firmenich Incorporated Sweet flavor modifier
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
US9067070B2 (en) 2013-03-12 2015-06-30 Medibotics Llc Dysgeusia-inducing neurostimulation for modifying consumption of a selected nutrient type
US9011365B2 (en) 2013-03-12 2015-04-21 Medibotics Llc Adjustable gastrointestinal bifurcation (AGB) for reduced absorption of unhealthy food
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
US9529385B2 (en) 2013-05-23 2016-12-27 Medibotics Llc Smart watch and human-to-computer interface for monitoring food consumption
US9826662B2 (en) 2013-12-12 2017-11-21 General Electric Company Reusable phase-change thermal interface structures
US10660571B2 (en) * 2013-12-19 2020-05-26 Kent State University Thermochromic fabrics utilizing cholesteric liquid crystal material
EP3104712B1 (en) 2014-02-12 2020-05-06 Firmenich Incorporated Improved process for the synthesis of substituted 1-benzyl-3-(1-(isoxazol-4-ylmethyl)-1h-pyrazol-4-yl)imidazolidine-2,4-diones
WO2015163905A1 (en) 2014-04-25 2015-10-29 General Mills, Inc. Food products having sweetness enhancer
JP6383704B2 (ja) * 2015-07-02 2018-08-29 日立オートモティブシステムズ株式会社 電池制御装置
BR112021002261A2 (pt) 2018-08-07 2021-05-04 Firmenich Incorporated 2,2-dióxidos de 4-amino-1h-benzo[c][1,2,6]tiadiazina 5-substituídos e formulações e usos dos mesmos
EP3693975A1 (en) 2019-02-06 2020-08-12 Tata Consultancy Services Limited System and method for evaluation of at least one potential tastant from a plurality of tastants
WO2021150686A1 (en) 2020-01-22 2021-07-29 Firmenich Incorporated High-sensitivity detection of gpcr activity and uses thereof
US11297861B2 (en) * 2020-06-25 2022-04-12 Mycotechnology, Inc. Sweet protein from truffle
CN116554350B (zh) * 2023-04-26 2024-01-09 之江实验室 基于人类甜味受体蛋白的生物传感器及其应用

Family Cites Families (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US788470A (en) * 1903-06-16 1905-04-25 Edouard Jehn Changing mechanism for picture-exhibitors.
US1733847A (en) * 1927-03-11 1929-10-29 Variety Fire Door Company Door-latch retainer
JPS5825980B2 (ja) 1976-02-12 1983-05-31 ヤマサ醤油株式会社 サイクリックヌクレオチドの定量法
US4391904A (en) 1979-12-26 1983-07-05 Syva Company Test strip kits in immunoassays and compositions therein
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4517288A (en) 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4661768A (en) * 1983-09-14 1987-04-28 Johnson Service Company Capacitance transducing method and apparatus
US5506337A (en) 1985-03-15 1996-04-09 Antivirals Inc. Morpholino-subunit combinatorial library and method
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
CA1291031C (en) 1985-12-23 1991-10-22 Nikolaas C.J. De Jaeger Method for the detection of specific binding agents and their correspondingbindable substances
US5010175A (en) 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
KR0176693B1 (ko) 1989-12-22 1999-04-01 레지널드 디. 쇼트보그; 제롬 반 쥘렌 조절요소를 사용한 내인성 유전자의 발현을 변형시키는 방법
US5272071A (en) 1989-12-22 1993-12-21 Applied Research Systems Ars Holding N.V. Method for the modification of the expression characteristics of an endogenous gene of a given cell line
EP0466874A1 (fr) 1990-02-09 1992-01-22 Asulab S.A. Micromoteur electrostatique a champ radial realise par microfabrication photolithographique et procede de realisation d'un tel micromoteur
IE66205B1 (en) 1990-06-14 1995-12-13 Paul A Bartlett Polypeptide analogs
US5650489A (en) 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
US5401629A (en) 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal
JPH06509702A (ja) 1991-04-05 1994-11-02 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク 匂い物質受容体およびその使用
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US6270989B1 (en) 1991-11-05 2001-08-07 Transkaryotic Therapies, Inc. Protein production and delivery
NZ245015A (en) 1991-11-05 1995-12-21 Transkaryotic Therapies Inc Delivery of human growth hormone through the administration of transfected cell lines encoding human growth hormone, which are physically protected from host immune response; the transfected cells and their production
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US6664107B1 (en) 1993-05-26 2003-12-16 Ontario Cancer Institute, University Health Network CD45 disrupted nucleic acid
US5426039A (en) 1993-09-08 1995-06-20 Bio-Rad Laboratories, Inc. Direct molecular cloning of primer extended DNA containing an alkane diol
EP0720650B1 (en) * 1993-09-20 2004-12-01 Novartis AG Human metabotropic glutamate receptor subtype hmglur7 and related dna compounds
IL108205A0 (en) 1993-12-28 1994-04-12 Yeda Res & Dev Olfactory genes and receptors
US5519134A (en) 1994-01-11 1996-05-21 Isis Pharmaceuticals, Inc. Pyrrolidine-containing monomers and oligomers
US5593853A (en) 1994-02-09 1997-01-14 Martek Corporation Generation and screening of synthetic drug libraries
US5691188A (en) 1994-02-14 1997-11-25 American Cyanamid Company Transformed yeast cells expressing heterologous G-protein coupled receptor
US5539083A (en) 1994-02-23 1996-07-23 Isis Pharmaceuticals, Inc. Peptide nucleic acid combinatorial libraries and improved methods of synthesis
US5525735A (en) 1994-06-22 1996-06-11 Affymax Technologies Nv Methods for synthesizing diverse collections of pyrrolidine compounds
US5549974A (en) 1994-06-23 1996-08-27 Affymax Technologies Nv Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof
JPH10510433A (ja) 1995-06-06 1998-10-13 アイシス・ファーマシューティカルス・インコーポレーテッド 高いキラル純度のホスホロチオエート結合を有するオリゴヌクレオチド
US5985662A (en) 1995-07-13 1999-11-16 Isis Pharmaceuticals Inc. Antisense inhibition of hepatitis B virus replication
AU1118197A (en) 1995-11-09 1997-05-29 Johns Hopkins University School Of Medicine, The Novel sperm receptors
US5874243A (en) 1997-03-28 1999-02-23 Smithkline Beecham Corporation OLRCC15 receptor
US5993778A (en) * 1997-05-07 1999-11-30 Firestein; Stuart J. Functional expression of, and assay for, functional cellular receptors in vivo
US5940153A (en) * 1998-04-03 1999-08-17 Motorola, Inc. Display assembly having LCD and seal captured between interlocking lens cover and lightpipe
FR2780405B1 (fr) 1998-06-25 2001-12-28 Centre Nat Rech Scient Nouveaux recepteurs olfactifs et leurs utilisations
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
US6383778B1 (en) 1998-07-28 2002-05-07 The Regents Of The University Of California Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
WO2000006719A1 (en) 1998-07-28 2000-02-10 The Regents Of The University Of California Nucleic acids encoding proteins involved in sensory transduction
AU5022399A (en) 1998-07-28 2000-02-21 Canadian Inovatech, Inc. Methods and compositions for inhibiting microbial growth in wine
KR100602857B1 (ko) * 1998-07-28 2006-07-20 더 리전트 오브 더 유니버시티 오브 캘리포니아 감각 정보 전달과 관련된 ｇ-단백질 커플링된 수용체를암호화하는 핵산
EP1100867B1 (en) 1998-07-28 2004-12-01 Victoria Ann Heslop Digester
US6106555A (en) 1998-12-15 2000-08-22 Av Healing Llc Method for tissue fixation
WO2000038536A2 (en) 1998-12-23 2000-07-06 Mount Sinai School Of Medicine Of New York University Inhibitors of the bitter taste response
US6558910B2 (en) 1999-09-10 2003-05-06 The Regents Of The University Of California SF, a novel family of taste receptors
WO2001018050A2 (en) 1999-09-10 2001-03-15 The Regents Of The University Of California T2r taste receptor family
US20030036089A1 (en) * 1999-12-20 2003-02-20 Applera Corporation Isolated human G-protein coupled receptors, nucleic acid molecules encoding human GPCR proteins, and uses thereof
WO2001064882A2 (en) * 2000-02-29 2001-09-07 Millennium Pharmaceuticals, Inc. 1983, 52881, 2398, 45449, 50289, and 52872, g protein-coupled receptors and uses therefor
TW201006846A (en) * 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
US6608176B2 (en) 2000-03-31 2003-08-19 University Of Miami Taste receptor for umami (monosodium glutamate) taste
IL152137A0 (en) 2000-04-07 2003-05-29 Senomyx Inc Tr2 taste receptors and genes encoding same
AU2001255681A1 (en) * 2000-04-28 2001-11-12 The Monell Chemical Senses Center Gene and sequence variation associated with sensing carbohydrate compounds and other sweeteners
JP2004513614A (ja) 2000-06-16 2004-05-13 インサイト・ゲノミックス・インコーポレイテッド Ｇタンパク質結合受容体
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US20080244761A1 (en) * 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US6955887B2 (en) 2001-03-30 2005-10-18 Senomyx, Inc. Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling
US7309577B2 (en) * 2001-03-07 2007-12-18 Senomyx, Inc. Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
US7763431B1 (en) 2001-03-07 2010-07-27 Senomyx, Inc. Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
WO2003001876A2 (en) 2001-06-26 2003-01-09 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
DK2327985T3 (en) * 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
JP2005505262A (ja) * 2001-07-03 2005-02-24 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 哺乳動物の甘味およびアミノ酸のヘテロダイマー性の味覚レセプター
WO2003025137A2 (en) 2001-09-18 2003-03-27 Irm, Llc Sweet taste receptors
CN1296374C (zh) * 2001-11-08 2007-01-24 北兴化学工业株式会社 生产三有机基－单烷氧基硅烷的方法以及生产三有机基－单氯硅烷的方法
US7208290B2 (en) * 2001-12-14 2007-04-24 Senomyx, Inc. Methods of co-expressing umami taste receptors and chimeric Gα15 variants
US7107837B2 (en) * 2002-01-22 2006-09-19 Baxter International Inc. Capacitance fluid volume measurement
US7441104B2 (en) 2002-03-30 2008-10-21 Hewlett-Packard Development Company, L.P. Parallel subword instructions with distributed results
US20070142748A1 (en) * 2002-04-19 2007-06-21 Ajay Deshmukh Tissue penetration device
US9314194B2 (en) * 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
IL165669A0 (en) 2002-07-29 2006-01-15 Senomyx Inc Identification of a novel bitter taste receptor t2r76
WO2004069191A2 (en) * 2003-02-03 2004-08-19 Senomyx Inc. Identification of t1r and t2r modulators
CN103275058B (zh) 2003-08-06 2016-02-24 西诺米克斯公司 调味剂、味道调节剂、促味剂、味觉增强剂、鲜味剂或甜味剂和/或增强剂及其用途
US7906627B2 (en) 2003-08-06 2011-03-15 Senomyx, Inc. Chimeric human sweet-umami and umami-sweet taste receptors
US20050106571A1 (en) 2003-10-02 2005-05-19 The Regents Of The University Of California Mammalian T1R3 sweet taste receptors
EP1680014A4 (en) * 2003-10-14 2009-01-21 Pelikan Technologies Inc METHOD AND APPARATUS PROVIDING A VARIABLE USER INTERFACE
EP1737345A1 (en) * 2004-04-15 2007-01-03 Roche Diagnostics GmbH Integrated spot monitoring device with fluid sensor
US20060045953A1 (en) 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
TWI399228B (zh) * 2006-07-21 2013-06-21 Alcon Inc 低黏性的眼科與耳鼻喉科裝置材料（二）
US20080047764A1 (en) * 2006-08-28 2008-02-28 Cypress Semiconductor Corporation Temperature compensation method for capacitive sensors
US20090061456A1 (en) 2007-08-30 2009-03-05 Allard William J Method for predicting progression free and overall survival at each follow-up time point during therapy of metastatic breast cancer patients using circulating tumor cells
US7936111B2 (en) 2008-08-07 2011-05-03 Samsung Electronics Co., Ltd. Apparatus for generating electrical energy and method for manufacturing the same
TWI552751B (zh) 2011-06-20 2016-10-11 Ｈ 朗德貝克公司 投予４－（（１ｒ，３ｓ）－６－氯－３－苯基－二氫茚－１－基）－１，２，２－三甲基－哌及其鹽用於治療精神***症的方法

Also Published As

Publication number Publication date
ES2396681T3 (es) 2013-02-25
US20110081658A1 (en) 2011-04-07
US20190085051A1 (en) 2019-03-21
US20090093051A1 (en) 2009-04-09
AU2001240086B2 (en) 2008-01-03
US20110207133A1 (en) 2011-08-25
US20100330590A1 (en) 2010-12-30
AU4008601A (en) 2001-09-17
US7524637B2 (en) 2009-04-28
EP2143732B1 (en) 2012-10-03
US20040132075A1 (en) 2004-07-08
US8247542B2 (en) 2012-08-21
EP1309606A4 (en) 2004-06-09
US20150299293A1 (en) 2015-10-22
US20040171042A1 (en) 2004-09-02
US20090233807A1 (en) 2009-09-17
ATE403669T1 (de) 2008-08-15
CA2402214A1 (en) 2001-09-13
US8314224B2 (en) 2012-11-20
ATE456577T1 (de) 2010-02-15
WO2001066563A8 (en) 2004-06-24
US8815525B2 (en) 2014-08-26
ES2311508T3 (es) 2009-02-16
US7842785B2 (en) 2010-11-30
US20090029455A1 (en) 2009-01-29
US7244835B2 (en) 2007-07-17
US20170313761A1 (en) 2017-11-02
TW201006846A (en) 2010-02-16
EP1944319B1 (en) 2010-01-27
CN101445800A (zh) 2009-06-03
US7223551B2 (en) 2007-05-29
US7737254B2 (en) 2010-06-15
EP2143732A1 (en) 2010-01-13
NO20024276D0 (no) 2002-09-06
DE60135229D1 (de) 2008-09-18
US20110207212A1 (en) 2011-08-25
US7799905B2 (en) 2010-09-21
WO2001066563A2 (en) 2001-09-13
JP2004513608A (ja) 2004-05-13
DE60141237D1 (de) 2010-03-18
US9637536B2 (en) 2017-05-02
CA2402214C (en) 2013-10-15
DK2298802T3 (da) 2013-01-02
US20090004676A1 (en) 2009-01-01
EP1944319A1 (en) 2008-07-16
US20090176657A1 (en) 2009-07-09
US7507544B2 (en) 2009-03-24
US20090053730A1 (en) 2009-02-26
EP1309606B1 (en) 2008-08-06
EP1309606A1 (en) 2003-05-14
US7452685B2 (en) 2008-11-18
US7705121B2 (en) 2010-04-27
JP5403842B2 (ja) 2014-01-29
WO2001066563A3 (en) 2004-05-27
US8263341B2 (en) 2012-09-11
DE01914732T1 (de) 2004-04-15
US20080213880A1 (en) 2008-09-04
US8816057B2 (en) 2014-08-26
US20110244563A1 (en) 2011-10-06
ES2338497T3 (es) 2010-05-07
US8802379B2 (en) 2014-08-12
CN1766108A (zh) 2006-05-03
EP2298802A1 (en) 2011-03-23
DK1309606T3 (da) 2008-11-24
US20130065235A1 (en) 2013-03-14
HK1139965A1 (en) 2010-09-30
US20040191805A1 (en) 2004-09-30
US7772385B2 (en) 2010-08-10
US7847080B2 (en) 2010-12-07
US20030008344A1 (en) 2003-01-09
US20080026404A1 (en) 2008-01-31
JP2013247957A (ja) 2013-12-12
DK1944319T3 (da) 2010-05-10
US20040229239A1 (en) 2004-11-18
US20080038741A1 (en) 2008-02-14
CN1543474A (zh) 2004-11-03
US20080233596A1 (en) 2008-09-25
US10544204B2 (en) 2020-01-28
US7927823B2 (en) 2011-04-19
US20130171727A1 (en) 2013-07-04
AU2001240086B9 (en) 2001-09-17
IL151578A0 (en) 2003-04-10
US10093718B2 (en) 2018-10-09
EP2298802B1 (en) 2012-10-24
US9040247B2 (en) 2015-05-26
JP5903078B2 (ja) 2016-04-13
US7834165B2 (en) 2010-11-16
US7790848B2 (en) 2010-09-07
MXPA02008724A (es) 2004-09-06

Similar Documents

Publication Publication Date Title
NO20024276D0 (no) TIR smaksreseptorer samt gener som koder for disse
NO20033030D0 (no) T1R smaksreseptorer og gener som koder for disse
MXPA02009843A (es) Receptores t2r del sabor y genes que codifican para los mismos.
WO2001068805A8 (en) Human olfactory receptors and genes encoding same
AU5301201A (en) Methods of modulating hair growth
DE60322426D1 (no)
ES2185560T3 (es) Sistema interactivo.
CY1110557T1 (el) Αντισωματα ιντερλευκινης-10
MX9301511A (es) Metodo y aparato para estimar los parametros de peso de la señal en un receptor de diversidades
ATE186738T1 (de) Kohlenhydratmodifizierte cytostatika
ATE483810T1 (de) Entkopplung von dna-propagierung und proteinexpression für phagen-display
ATE360701T1 (de) Putrescin-n-methyltransferasepromotor
DE69840637D1 (de) Zusammensetzungen zur steigerung der effizienz von impfstoffen unter verwendung von chemokinen
DK1685471T3 (da) Individuel gyldighedsperiode for password, PIN-kode og kodefrase
ATE361376T1 (de) Membranfraktionen von mit 1,2-sn-diacylglycerol angereicherten zellen
SG140586A1 (en) Methods
HRPK20030026B3 (en) Flying saucer

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application