NO20024198L - Fremgangsmåte ved fremstilling av citalopram - Google Patents

Fremgangsmåte ved fremstilling av citalopram

Info

Publication number
NO20024198L
NO20024198L NO20024198A NO20024198A NO20024198L NO 20024198 L NO20024198 L NO 20024198L NO 20024198 A NO20024198 A NO 20024198A NO 20024198 A NO20024198 A NO 20024198A NO 20024198 L NO20024198 L NO 20024198L
Authority
NO
Norway
Prior art keywords
group
citalopram
cyano
cor
hydrogen
Prior art date
Application number
NO20024198A
Other languages
English (en)
Other versions
NO20024198D0 (no
Inventor
Hans Petersen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO20024198L publication Critical patent/NO20024198L/no
Publication of NO20024198D0 publication Critical patent/NO20024198D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Cephalosporin Compounds (AREA)
NO20024198A 2000-03-14 2002-09-03 Fremgangsmåte ved fremstilling av citalopram NO20024198D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000415 2000-03-14
PCT/DK2001/000162 WO2001068630A1 (en) 2000-03-14 2001-03-09 Method for the preparation of citalopram

Publications (2)

Publication Number Publication Date
NO20024198L true NO20024198L (no) 2002-09-03
NO20024198D0 NO20024198D0 (no) 2002-09-03

Family

ID=8159331

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20024198A NO20024198D0 (no) 2000-03-14 2002-09-03 Fremgangsmåte ved fremstilling av citalopram

Country Status (26)

Country Link
US (1) US6806376B2 (no)
EP (1) EP1265882B1 (no)
JP (1) JP2003527386A (no)
KR (1) KR20020080476A (no)
CN (1) CN1418205A (no)
AT (1) ATE257832T1 (no)
AU (1) AU2001239213A1 (no)
BG (1) BG107051A (no)
BR (1) BR0109268A (no)
CA (1) CA2402557A1 (no)
DE (1) DE60101786T2 (no)
DK (1) DK1265882T3 (no)
EA (1) EA005094B1 (no)
ES (1) ES2214400T3 (no)
HR (1) HRP20020740A2 (no)
HU (1) HUP0300178A2 (no)
IL (1) IL151488A0 (no)
IS (1) IS6527A (no)
MX (1) MXPA02008653A (no)
NO (1) NO20024198D0 (no)
PL (1) PL360107A1 (no)
PT (1) PT1265882E (no)
SK (1) SK14512002A3 (no)
TR (2) TR200400611T4 (no)
WO (1) WO2001068630A1 (no)
ZA (1) ZA200206897B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1142926C (zh) * 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NZ521201A (en) 2000-03-13 2004-02-27 H Method for the preparation of citalopram
EP1265881A1 (en) 2000-03-13 2002-12-18 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
PE20040991A1 (es) 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
TWI339651B (en) 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (no) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
DE1015416T1 (de) 1997-07-08 2000-10-05 Lundbeck A S Kobenhavn Valby H Verfahren zur herstellung von citalopram
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
JP3813820B2 (ja) 1997-11-11 2006-08-23 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
EA003057B1 (ru) 1998-12-23 2002-12-26 Х.Лундбекк А/С Способ получения 5-цианофталида
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
CN1142926C (zh) 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
EP1228056B1 (en) 1999-10-25 2004-09-22 H. Lundbeck A/S Method for the preparation of citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
PT1246812E (pt) 1999-12-28 2004-08-31 Lundbeck & Co As H Metodo para a preparacao de citalopram
EP1246813B1 (en) 1999-12-30 2003-11-05 H. Lundbeck A/S Method for the preparation of citalopram
ATE252570T1 (de) 2000-01-14 2003-11-15 Lundbeck & Co As H Verfahren zur herstellung von 5-cyanophthalid
US6433196B1 (en) 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
NZ521201A (en) 2000-03-13 2004-02-27 H Method for the preparation of citalopram
EA200200982A1 (ru) 2000-03-16 2003-02-27 Х.Лундбекк А/С Способ получения 5-циано-1-(4-фторфенил)-1,3-дигидроизобензофуранов
CZ2002832A3 (cs) 2000-07-06 2002-05-15 H. Lundbeck A/S Způsob výroby citalopramu
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
CA2360303C (en) 2000-12-22 2003-08-12 Marco Villa Process for the preparation of pure citalopram
PT1181272E (pt) 2000-12-28 2003-01-31 Lundbeck & Co As H Processo para a preparacao de citalopram puro

Also Published As

Publication number Publication date
TR200400611T4 (tr) 2004-04-21
AU2001239213A1 (en) 2001-09-24
IS6527A (is) 2002-08-27
DE60101786D1 (de) 2004-02-19
MXPA02008653A (es) 2003-02-24
SK14512002A3 (sk) 2003-03-04
IL151488A0 (en) 2003-04-10
US6806376B2 (en) 2004-10-19
HRP20020740A2 (en) 2004-12-31
US20030050484A1 (en) 2003-03-13
CN1418205A (zh) 2003-05-14
ES2214400T3 (es) 2004-09-16
CA2402557A1 (en) 2001-09-20
EP1265882A1 (en) 2002-12-18
PL360107A1 (en) 2004-09-06
DE60101786T2 (de) 2004-07-15
BG107051A (en) 2003-05-30
NO20024198D0 (no) 2002-09-03
TR200202155T2 (tr) 2002-12-23
WO2001068630A1 (en) 2001-09-20
EP1265882B1 (en) 2004-01-14
BR0109268A (pt) 2002-12-03
EA005094B1 (ru) 2004-10-28
HUP0300178A2 (en) 2003-05-28
ATE257832T1 (de) 2004-01-15
JP2003527386A (ja) 2003-09-16
PT1265882E (pt) 2004-06-30
KR20020080476A (ko) 2002-10-23
EA200200970A1 (ru) 2003-02-27
ZA200206897B (en) 2003-08-28
DK1265882T3 (da) 2004-06-01

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application