NO1994023I1 - Sumatriptan - Google Patents

Sumatriptan

Info

Publication number
NO1994023I1
NO1994023I1 NO1994023C NO1994023C NO1994023I1 NO 1994023 I1 NO1994023 I1 NO 1994023I1 NO 1994023 C NO1994023 C NO 1994023C NO 1994023 C NO1994023 C NO 1994023C NO 1994023 I1 NO1994023 I1 NO 1994023I1
Authority
NO
Norway
Prior art keywords
sumatriptan
Prior art date
Application number
NO1994023C
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10564759&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO1994023(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO1994023I1 publication Critical patent/NO1994023I1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C07D203/14—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom with carbocyclic rings directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO1994023C 1984-08-01 1994-11-09 Sumatriptan NO1994023I1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848419575A GB8419575D0 (en) 1984-08-01 1984-08-01 Chemical compounds

Publications (1)

Publication Number Publication Date
NO1994023I1 true NO1994023I1 (no) 1994-11-09

Family

ID=10564759

Family Applications (2)

Application Number Title Priority Date Filing Date
NO853046A NO164653C (no) 1984-08-01 1985-08-01 Analogifremgangsmaate for fremstilling av et terapeutisk aktivt indol-derivat.
NO1994023C NO1994023I1 (no) 1984-08-01 1994-11-09 Sumatriptan

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO853046A NO164653C (no) 1984-08-01 1985-08-01 Analogifremgangsmaate for fremstilling av et terapeutisk aktivt indol-derivat.

Country Status (42)

Country Link
US (1) US5037845A (no)
JP (1) JPH0623197B2 (no)
KR (1) KR930003759B1 (no)
AT (1) AT386196B (no)
AU (1) AU573878B2 (no)
BE (1) BE903006A (no)
CA (1) CA1241004A (no)
CH (1) CH666026A5 (no)
CZ (1) CZ280530B6 (no)
DE (1) DE3527648A1 (no)
DK (1) DK158942C (no)
DO (1) DOP1989004759A (no)
EC (1) ECSP941096A (no)
EG (1) EG17283A (no)
ES (6) ES8700234A1 (no)
FI (1) FI78466C (no)
FR (1) FR2568571B1 (no)
GB (1) GB8419575D0 (no)
GR (1) GR851850B (no)
HK (1) HK33289A (no)
HU (1) HU201738B (no)
IE (1) IE58122B1 (no)
IL (1) IL75986A (no)
IS (1) IS1430B6 (no)
IT (1) IT1207325B (no)
JO (1) JO1379B1 (no)
KE (1) KE3858A (no)
LU (2) LU86032A1 (no)
MA (1) MA20499A1 (no)
MX (2) MX159672A (no)
NL (2) NL188642C (no)
NO (2) NO164653C (no)
NZ (1) NZ212948A (no)
PH (2) PH22850A (no)
PL (1) PL146005B1 (no)
PT (1) PT80900B (no)
SE (1) SE452460B (no)
SK (1) SK404191A3 (no)
SU (1) SU1498386A3 (no)
UA (1) UA6329A1 (no)
ZA (1) ZA855818B (no)
ZW (1) ZW12485A1 (no)

Families Citing this family (65)

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US5270333A (en) * 1986-01-28 1993-12-14 Glaxo Group Limited Indole derivatives
US5155218A (en) * 1990-05-08 1992-10-13 Neurogenetic Corporation Dna encoding human 5-ht1d receptors
US5935925A (en) * 1990-05-08 1999-08-10 Synaptic Pharmaceutical Corporation Methods of treating migraine and compounds useful for such methods
GB9013845D0 (en) * 1990-06-21 1990-08-15 Glaxo Group Ltd Process
GB9022250D0 (en) * 1990-10-12 1990-11-28 Glaxo Group Ltd Medicaments
GB9101592D0 (en) * 1991-01-24 1991-03-06 Glaxo Group Ltd Compositions
GB9102579D0 (en) * 1991-01-24 1991-03-27 Glaxo Group Ltd Compositions
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
GB9104890D0 (en) * 1991-03-08 1991-04-24 Glaxo Group Ltd Compositions
AT399870B (de) * 1991-06-06 1995-08-25 Vita Invest Sa Verfahren zur herstellung von 3-(2-(dimethylamino)ethyl)-n-methyl-1h-indol-5- ethansulfonamid
GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
ES2059236B1 (es) * 1992-06-18 1995-06-16 Imidex S A Procedimiento para la sintesis de la 3-(2-dimetilamino) etil)-n-metil-1h-indol-5-metanosulfonamida.
ES2055651B1 (es) * 1992-07-20 1995-03-01 Vita Invest Sa Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles.
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
AT399871B (de) * 1993-02-15 1995-08-25 Vita Invest Sa Verfahren zur herstellung von 2-carboxy-3-(2- (dimethylamino)ethyl)-n-methyl-1h-indol-5- methansulfonamid und dessen niederalkylestern
US5807571A (en) * 1993-05-06 1998-09-15 Lts Lohmann Therapie-Systeme Gmbh Transdermal therapeutic systems for administering indole serotonin agonists
GB9401436D0 (en) * 1994-01-26 1994-03-23 Wellcome Found Therapeutic heterocyclic compounds
ES2084560B1 (es) * 1994-03-09 1997-01-16 Almirall Lab Procedimiento de preparacion de derivados el indol.
ES2079323B1 (es) * 1994-06-21 1996-10-16 Vita Invest Sa Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes.
EP0804434A1 (en) * 1994-08-02 1997-11-05 MERCK SHARP & DOHME LTD. Azetidine, pyrrolidine and piperidine derivatives
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US8022095B2 (en) 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
WO1998011895A1 (en) * 1996-09-18 1998-03-26 Eli Lilly And Company A method for the prevention of migraine
JP2001501946A (ja) * 1996-10-08 2001-02-13 イーライ・リリー・アンド・カンパニー 新規セロトニン５―ｈｔ▲下１ｆ▼アゴニスト
GB9714383D0 (en) * 1997-07-08 1997-09-10 Pfizer Ltd Improved process
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US6066092A (en) * 1997-11-06 2000-05-23 Cady; Roger K. Preemptive prophylaxis of migraine device and method
US6416472B1 (en) 1997-11-06 2002-07-09 Edus Inc. Method and device for measuring cognitive efficiency
AT500063A1 (de) * 1999-11-23 2005-10-15 Sandoz Ag Beschichtete tablettenkerne
JP4959907B2 (ja) * 2001-03-27 2012-06-27 ワーナー チルコット（アイルランド）リミティド 抗菌剤投与のための膣内用ドラッグデリバリーデバイス
ES2312585T3 (es) * 2001-06-05 2009-03-01 Ronald Aung-Din Terapia contra la migraña por via topica.
US8329734B2 (en) * 2009-07-27 2012-12-11 Afgin Pharma Llc Topical therapy for migraine
FR2827287B1 (fr) * 2001-07-13 2003-10-31 Servier Lab Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
US20060106227A1 (en) * 2002-06-13 2006-05-18 Dr Reddy's Laboratories Limited 3-'2-(Dimethylamino) ethyl!-n-methyl-1h-indole-5-methanesulfonamide and the succinate thereof
US20040068000A1 (en) * 2002-10-02 2004-04-08 Mintong Guo Compression coated tablets
CN1176649C (zh) * 2002-10-16 2004-11-24 上海医药工业研究院 舒马普坦干粉吸入剂及其制备方法
JP4897221B2 (ja) 2002-12-20 2012-03-14 チバ ホールディング インコーポレーテッド アミン類の合成及びその合成のための中間体
US20080213363A1 (en) * 2003-01-23 2008-09-04 Singh Nikhilesh N Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa
WO2004076403A1 (en) * 2003-02-24 2004-09-10 Transform Pharmaceuticals, Inc. Sumatriptan crystalline forms, pharmaceutical compositions and methods
US20070054953A1 (en) * 2003-05-12 2007-03-08 Potluri Ramesh B A novel process for preparation of indole derivatives
US20070184109A1 (en) * 2003-06-06 2007-08-09 Floyd Alison G Compositions comprising triptans and nsaids
US20070065463A1 (en) * 2003-06-20 2007-03-22 Ronald Aung-Din Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions
GB2407498B (en) * 2003-10-30 2008-06-11 Cipla Ltd Oral formulations for 5-HT receptor agonists with reduced degradation of active ingredient
EP1765300A2 (en) * 2004-06-10 2007-03-28 Duramed Pharmaceuticals, Inc. Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same
PL1883451T3 (pl) 2005-04-13 2011-05-31 Neuraxon Inc Podstawione związki indolowe mające aktywność hamowania NOS
US20070166336A1 (en) * 2005-12-13 2007-07-19 David Delmarre Stable and palatable oral liquid sumatriptan compositions
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US20090076121A1 (en) * 2007-09-14 2009-03-19 Protia, Llc Deuterium-enriched sumatriptan
US20090131503A1 (en) * 2007-11-16 2009-05-21 Annedi Subhash C 3,5 - substituted indole compounds having nos and norepinephrine reuptake inhibitory activity
AU2008321353A1 (en) * 2007-11-16 2009-05-22 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for treating visceral pain
CN101910157B (zh) * 2007-11-16 2014-05-07 纽尔亚商股份有限公司 吲哚化合物和治疗内脏痛的方法
WO2009128089A2 (en) * 2008-02-11 2009-10-22 Matrix Laboratories Limited Novel solvate form of sumatriptan succinate and process for preparing sumatriptan salt employing the same
US20090252791A1 (en) * 2008-04-02 2009-10-08 Venkata Nookaraju Sreedharala Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug
KR101517415B1 (ko) 2008-05-14 2015-05-07 에스케이바이오팜 주식회사 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물
US8592424B2 (en) * 2008-06-30 2013-11-26 Afgin Pharma Llc Topical regional neuro-affective therapy
WO2010046399A1 (en) * 2008-10-22 2010-04-29 Novartis Ag Combinations for the treatment of migraine
NZ599344A (en) 2009-09-25 2015-02-27 Reddy’S Lab Ltd Dr Formulations comprising triptan compounds
US11337962B2 (en) 2009-09-25 2022-05-24 Upsher-Smith Laboratories, Llc Formulations comprising triptan compounds
JP5660817B2 (ja) * 2010-07-21 2015-01-28 高田製薬株式会社 スマトリプタンコハク酸塩を含有する内用液剤
CN102432520B (zh) * 2011-11-21 2013-10-09 山东新华制药股份有限公司 3-[2-（二甲氨基）乙基]-n-甲基吲哚-5-甲烷磺酰胺琥珀酸盐的制备方法
WO2016141056A1 (en) 2015-03-02 2016-09-09 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoids
US10383816B2 (en) 2015-03-02 2019-08-20 Afgin Pharma, Llc Topical regional neuro-affective therapy with cannabinoid combination products
US20180049994A1 (en) 2016-08-16 2018-02-22 Afgin Pharma, Llc Topical regional neuro-affective therapy with caryophyllene

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DE311728C (no) *
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IT1036004B (it) * 1968-05-21 1979-10-30 Abc Ist Biolog Chem Spa Acidt 3 indolil adetoidrossamici
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CH651551A5 (fr) * 1980-08-12 1985-09-30 Glaxo Group Ltd Derives de l'indole, leur preparation et compositions pharmaceutiques les contenant.
IT1170387B (it) * 1982-06-07 1987-06-03 Glaxo Group Ltd Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
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HU196752B (en) * 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds

Also Published As

Publication number Publication date
IS1430B6 (is) 1990-07-16
MX14221A (es) 1993-10-01
HUT40077A (en) 1986-11-28
ZA855818B (en) 1986-04-30
PH22850A (en) 1989-01-19
HK33289A (en) 1989-04-28
PT80900B (pt) 1987-12-30
IE851918L (en) 1986-02-01
NL930065I1 (nl) 1993-09-01
SU1498386A3 (ru) 1989-07-30
KR860001788A (ko) 1986-03-22
PH24117A (en) 1990-03-05
DOP1989004759A (es) 1999-02-06
PL146005B1 (en) 1988-12-31
LU86032A1 (fr) 1986-02-18
ZW12485A1 (en) 1986-02-26
KE3858A (en) 1989-06-02
MX159672A (es) 1989-08-02
ES545810A0 (es) 1986-10-16
DK158942C (da) 1991-01-21
AU573878B2 (en) 1988-06-23
KR930003759B1 (ko) 1993-05-10
ES557483A0 (es) 1988-02-16
JPS6147464A (ja) 1986-03-07
CH666026A5 (fr) 1988-06-30
DE3527648A1 (de) 1986-02-13
ATA226685A (de) 1987-12-15
CA1241004A (en) 1988-08-23
SE452460B (sv) 1987-11-30
EG17283A (en) 1992-06-30
SK277952B6 (en) 1995-09-13
FI78466C (fi) 1989-08-10
US5037845A (en) 1991-08-06
DK351185D0 (da) 1985-08-01
JO1379B1 (en) 1986-11-30
FI78466B (fi) 1989-04-28
DK158942B (da) 1990-08-06
NL930065I2 (nl) 1993-10-01
NO164653B (no) 1990-07-23
GB8419575D0 (en) 1984-09-05
IS3034A7 (is) 1986-02-02
IT8548435A0 (it) 1985-08-01
PL254800A1 (en) 1986-10-21
MA20499A1 (fr) 1986-04-01
ES8801790A1 (es) 1988-02-16
IL75986A (en) 1989-02-28
UA6329A1 (uk) 1994-12-29
FI852969L (fi) 1986-02-02
AT386196B (de) 1988-07-11
IL75986A0 (en) 1985-12-31
DE3527648C2 (no) 1993-08-26
CZ280530B6 (cs) 1996-02-14
IE58122B1 (en) 1993-07-14
ES8801788A1 (es) 1988-02-16
NL8502171A (nl) 1986-03-03
PT80900A (en) 1985-09-01
NZ212948A (en) 1989-05-29
ES8801789A1 (es) 1988-02-16
ES8700234A1 (es) 1986-10-16
BE903006A (fr) 1986-02-03
GR851850B (no) 1985-11-26
ECSP941096A (es) 1995-01-16
ES557480A0 (es) 1988-02-16
ES557482A0 (es) 1988-03-01
ES557481A0 (es) 1988-02-16
IT1207325B (it) 1989-05-17
FR2568571A1 (fr) 1986-02-07
DK351185A (da) 1986-02-02
FI852969A0 (fi) 1985-08-01
SK404191A3 (en) 1995-09-13
ES552047A0 (es) 1987-12-16
FR2568571B1 (fr) 1988-09-23
ES8801204A1 (es) 1987-12-16
LU88266I2 (no) 1994-02-03
NO853046L (no) 1986-02-03
HU201738B (en) 1990-12-28
JPH0623197B2 (ja) 1994-03-30
CZ404191A3 (en) 1993-04-14
AU4568985A (en) 1986-02-06
ES8801900A1 (es) 1988-03-01
SE8503680L (sv) 1986-02-02
SE8503680D0 (sv) 1985-08-01
NO164653C (no) 1990-11-07
NL188642C (nl) 1992-08-17

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