DK351185A - Indolderivater - Google Patents

Indolderivater Download PDF

Info

Publication number: DK351185A
Authority: DK; Denmark
Prior art keywords: indole derivatives; indole; derivatives
Prior art date: 1984-08-01

Application number

DK351185A

Other languages

English (en)

Other versions

DK351185D0 (da

DK158942C (da

DK158942B (da

Inventor

Alexander William Oxford

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-08-01

Filing date

1985-08-01

Publication date

1986-02-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10564759&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK351185(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1985-08-01 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1985-08-01 Publication of DK351185D0 publication Critical patent/DK351185D0/da

1986-02-02 Publication of DK351185A publication Critical patent/DK351185A/da

1990-08-06 Publication of DK158942B publication Critical patent/DK158942B/da

1991-01-21 Application granted granted Critical

1991-01-21 Publication of DK158942C publication Critical patent/DK158942C/da

Links

0 CCC**(CC=C1*C1)C1[C@](CC)[C@]2[C@@](C)C2C1 Chemical compound CCC**(CC=C1*C1)C1[C@](CC)[C@]2[C@@](C)C2C1 0.000 description 3

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
- C07D203/14—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom with carbocyclic rings directly attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK351185A 1984-08-01 1985-08-01 3-(2-(dimethylamino)ethyl)-n-methyl-1h-indol-5-methansulfonamid, farmaceutiske praeparater indeholdende denne forbindelse samt fremgangsmaader til fremstilling af forbindelsen DK158942C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB8419575		1984-08-01
GB848419575A GB8419575D0 (en)	1984-08-01	1984-08-01	Chemical compounds

Publications (4)

Publication Number	Publication Date
DK351185D0 DK351185D0 (da)	1985-08-01
DK351185A true DK351185A (da)	1986-02-02
DK158942B DK158942B (da)	1990-08-06
DK158942C DK158942C (da)	1991-01-21

Family

ID=10564759

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK351185A DK158942C (da)	1984-08-01	1985-08-01	3-(2-(dimethylamino)ethyl)-n-methyl-1h-indol-5-methansulfonamid, farmaceutiske praeparater indeholdende denne forbindelse samt fremgangsmaader til fremstilling af forbindelsen

Country Status (42)

Country	Link
US (1)	US5037845A (da)
JP (1)	JPH0623197B2 (da)
KR (1)	KR930003759B1 (da)
AT (1)	AT386196B (da)
AU (1)	AU573878B2 (da)
BE (1)	BE903006A (da)
CA (1)	CA1241004A (da)
CH (1)	CH666026A5 (da)
CZ (1)	CZ280530B6 (da)
DE (1)	DE3527648A1 (da)
DK (1)	DK158942C (da)
DO (1)	DOP1989004759A (da)
EC (1)	ECSP941096A (da)
EG (1)	EG17283A (da)
ES (6)	ES8700234A1 (da)
FI (1)	FI78466C (da)
FR (1)	FR2568571B1 (da)
GB (1)	GB8419575D0 (da)
GR (1)	GR851850B (da)
HK (1)	HK33289A (da)
HU (1)	HU201738B (da)
IE (1)	IE58122B1 (da)
IL (1)	IL75986A (da)
IS (1)	IS1430B6 (da)
IT (1)	IT1207325B (da)
JO (1)	JO1379B1 (da)
KE (1)	KE3858A (da)
LU (2)	LU86032A1 (da)
MA (1)	MA20499A1 (da)
MX (2)	MX159672A (da)
NL (2)	NL188642C (da)
NO (2)	NO164653C (da)
NZ (1)	NZ212948A (da)
PH (2)	PH22850A (da)
PL (1)	PL146005B1 (da)
PT (1)	PT80900B (da)
SE (1)	SE452460B (da)
SK (1)	SK404191A3 (da)
SU (1)	SU1498386A3 (da)
UA (1)	UA6329A1 (da)
ZA (1)	ZA855818B (da)
ZW (1)	ZW12485A1 (da)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
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US5270333A (en) *	1986-01-28	1993-12-14	Glaxo Group Limited	Indole derivatives
US5155218A (en) *	1990-05-08	1992-10-13	Neurogenetic Corporation	Dna encoding human 5-ht1d receptors
US5935925A (en) *	1990-05-08	1999-08-10	Synaptic Pharmaceutical Corporation	Methods of treating migraine and compounds useful for such methods
GB9013845D0 (en) *	1990-06-21	1990-08-15	Glaxo Group Ltd	Process
GB9022250D0 (en) *	1990-10-12	1990-11-28	Glaxo Group Ltd	Medicaments
GB9101592D0 (en) *	1991-01-24	1991-03-06	Glaxo Group Ltd	Compositions
GB9102579D0 (en) *	1991-01-24	1991-03-27	Glaxo Group Ltd	Compositions
SK278998B6 (sk) *	1991-02-01	1998-05-06	Merck Sharp & Dohme Limited	Deriváty imidazolu, triazolu a tetrazolu, spôsob i
GB9104890D0 (en)	1991-03-08	1991-04-24	Glaxo Group Ltd	Compositions
AT399870B (de) *	1991-06-06	1995-08-25	Vita Invest Sa	Verfahren zur herstellung von 3-(2-(dimethylamino)ethyl)-n-methyl-1h-indol-5- ethansulfonamid
GB9209882D0 (en) *	1992-05-07	1992-06-24	Glaxo Lab Sa	Compositions
ES2059236B1 (es) *	1992-06-18	1995-06-16	Imidex S A	Procedimiento para la sintesis de la 3-(2-dimetilamino) etil)-n-metil-1h-indol-5-metanosulfonamida.
ES2055651B1 (es) *	1992-07-20	1995-03-01	Vita Invest Sa	Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles.
IL106445A (en) *	1992-07-30	1998-01-04	Merck Sharp & Dohme	History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
AT399871B (de) *	1993-02-15	1995-08-25	Vita Invest Sa	Verfahren zur herstellung von 2-carboxy-3-(2- (dimethylamino)ethyl)-n-methyl-1h-indol-5- methansulfonamid und dessen niederalkylestern
US5807571A (en) *	1993-05-06	1998-09-15	Lts Lohmann Therapie-Systeme Gmbh	Transdermal therapeutic systems for administering indole serotonin agonists
GB9401436D0 (en) *	1994-01-26	1994-03-23	Wellcome Found	Therapeutic heterocyclic compounds
ES2084560B1 (es) *	1994-03-09	1997-01-16	Almirall Lab	Procedimiento de preparacion de derivados el indol.
ES2079323B1 (es) *	1994-06-21	1996-10-16	Vita Invest Sa	Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes.
JPH10503768A (ja) *	1994-08-02	1998-04-07	メルクシヤープエンドドームリミテツド	アゼチジン、ピロリジンおよびピペリジン誘導体
US5521197A (en)	1994-12-01	1996-05-28	Eli Lilly And Company	3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists
US8022095B2 (en)	1996-08-16	2011-09-20	Pozen, Inc.	Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
AU4074897A (en) *	1996-09-18	1998-04-14	Eli Lilly And Company	A method for the prevention of migraine
US5792763A (en) *	1996-10-08	1998-08-11	Eli Lilly And Company	Serotonin 5-HT1F agonists
GB9714383D0 (en) *	1997-07-08	1997-09-10	Pfizer Ltd	Improved process
US6416472B1 (en)	1997-11-06	2002-07-09	Edus Inc.	Method and device for measuring cognitive efficiency
US7189753B1 (en)	1997-11-06	2007-03-13	Cady Roger K	Preemptive prophylaxis of migraine
US6066092A (en) *	1997-11-06	2000-05-23	Cady; Roger K.	Preemptive prophylaxis of migraine device and method
AT500063A1 (de) *	1999-11-23	2005-10-15	Sandoz Ag	Beschichtete tablettenkerne
EP1372605A2 (en) *	2001-03-27	2004-01-02	Galen (Chemicals) Limited	Intravaginal drug delivery devices for the administration of an antimicrobial agent
US8329734B2 (en) *	2009-07-27	2012-12-11	Afgin Pharma Llc	Topical therapy for migraine
ATE404193T1 (de) *	2001-06-05	2008-08-15	Ronald Aung-Din	Topische migränetherapie
FR2827287B1 (fr) *	2001-07-13	2003-10-31	Servier Lab	Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP1490090A4 (en)	2002-02-22	2006-09-20	New River Pharmaceuticals Inc	SYSTEMS FOR DELIVERING ACTIVE AGENTS AND METHODS FOR PROTECTING AND DELIVERING ACTIVE AGENTS
US20060106227A1 (en) *	2002-06-13	2006-05-18	Dr Reddy's Laboratories Limited	3-'2-(Dimethylamino) ethyl!-n-methyl-1h-indole-5-methanesulfonamide and the succinate thereof
US20040068000A1 (en) *	2002-10-02	2004-04-08	Mintong Guo	Compression coated tablets
CN1176649C (zh) *	2002-10-16	2004-11-24	上海医药工业研究院	舒马普坦干粉吸入剂及其制备方法
AU2003299227A1 (en) *	2002-12-20	2004-07-14	Ciba Specialty Chemicals Holding Inc.	Synthesis of amines and intermediates for the synthesis thereof
US20080213363A1 (en) *	2003-01-23	2008-09-04	Singh Nikhilesh N	Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa
WO2004076403A1 (en) *	2003-02-24	2004-09-10	Transform Pharmaceuticals, Inc.	Sumatriptan crystalline forms, pharmaceutical compositions and methods
US20070054953A1 (en) *	2003-05-12	2007-03-08	Potluri Ramesh B	A novel process for preparation of indole derivatives
CA2527368A1 (en) *	2003-06-06	2004-12-23	Glaxo Group Limited	Pharmaceutical composition
EP1644004A4 (en) *	2003-06-20	2010-10-06	Ronald Aung-Din	LOCAL THERAPY FOR THE TREATMENT OF MIGRAINS, MUSCLE CLARIFICATIONS, MUSCLE SPASMS, SPASTICITY AND RELATED CONDITIONS
GB2407498B (en) *	2003-10-30	2008-06-11	Cipla Ltd	Oral formulations for 5-HT receptor agonists with reduced degradation of active ingredient
WO2005123043A2 (en) *	2004-06-10	2005-12-29	Duramed Pharmaceuticals, Inc.	Formulations of sumatriptan for absorption across biological membranes, and methods of making and using the same
TWI466879B (zh)	2005-04-13	2015-01-01	Neuraxon Inc	具有一氧化氮合成酶抑制活性之取代的吲哚化合物
WO2007070504A2 (en) *	2005-12-13	2007-06-21	Morton Grove Pharmaceuticals, Inc.	Stable and palatable oral liquid sumatriptan compositions
TW200808780A (en) *	2006-04-13	2008-02-16	Neuraxon Inc	1,5 and 3,6- substituted indole compounds having NOS inhibitory activity
BRPI0715579A2 (pt) *	2006-10-19	2015-05-26	Auspex Pharmaceuticals Inc	"composto, composição farmacêutica e uso de um composto"
US20090076121A1 (en) *	2007-09-14	2009-03-19	Protia, Llc	Deuterium-enriched sumatriptan
EP2220074A4 (en) *	2007-11-16	2012-01-04	Neuraxon Inc	3,5-SUBSTITUTED INDOL COMPOUNDS WITH NOS AND NOREPINEPHRINE RECOVERY-HEMDERING EFFECT
WO2009064505A1 (en) *	2007-11-16	2009-05-22	The Arizona Board Of Regents On Behalf Of The University Of Arizona	Methods for treating visceral pain
NZ586082A (en) *	2007-11-16	2013-03-28	Neuraxon Inc	Indole compounds and methods for treating visceral pain
WO2009128089A2 (en) *	2008-02-11	2009-10-22	Matrix Laboratories Limited	Novel solvate form of sumatriptan succinate and process for preparing sumatriptan salt employing the same
US20090252791A1 (en) *	2008-04-02	2009-10-08	Venkata Nookaraju Sreedharala	Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug
KR101517415B1 (ko)	2008-05-14	2015-05-07	에스케이바이오팜 주식회사	난용성 항경련제를 함유하는 경비 항경련성 약학 조성물
EP2296652B1 (en) *	2008-06-30	2017-11-08	Afgin Pharma, Llc	Topical regional neuro-affective therapy
WO2010046399A1 (en) *	2008-10-22	2010-04-29	Novartis Ag	Combinations for the treatment of migraine
US11337962B2 (en)	2009-09-25	2022-05-24	Upsher-Smith Laboratories, Llc	Formulations comprising triptan compounds
RU2012116452A (ru)	2009-09-25	2013-10-27	Др. Редди'С Лабораторис Лимитед	Композиции, содержащие триптановые соединения
JP5660817B2 (ja) *	2010-07-21	2015-01-28	高田製薬株式会社	スマトリプタンコハク酸塩を含有する内用液剤
CN102432520B (zh) *	2011-11-21	2013-10-09	山东新华制药股份有限公司	3-[2-（二甲氨基）乙基]-n-甲基吲哚-5-甲烷磺酰胺琥珀酸盐的制备方法
CN107530318A (zh)	2015-03-02	2018-01-02	阿福金制药有限责任公司	用***素的局部区域神经影响性疗法
US10383816B2 (en)	2015-03-02	2019-08-20	Afgin Pharma, Llc	Topical regional neuro-affective therapy with cannabinoid combination products
US20180049994A1 (en)	2016-08-16	2018-02-22	Afgin Pharma, Llc	Topical regional neuro-affective therapy with caryophyllene

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DE311728C (da) *
US3322787A (en) *	1964-09-25	1967-05-30	Merck & Co Inc	Alpha-hydrazino-beta-(3-indolyl) alkanoic acid derivatives
IT1036004B (it) *	1968-05-21	1979-10-30	Abc Ist Biolog Chem Spa	Acidt 3 indolil adetoidrossamici
US4283410A (en) *	1978-06-15	1981-08-11	Miles Laboratories, Inc.	3-Amino or amido-2-(1H-indol-3-yl) propanoic acid derivatives
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
CH652394A5 (fr) *	1980-08-12	1985-11-15	Glaxo Group Ltd	Derives indoliques, leur preparation et medicaments les renfermant.
ZW19381A1 (en) *	1980-08-12	1983-03-09	Glaxo Group Ltd	Heterocyclic compounds
ZA815540B (en) *	1980-08-12	1983-03-30	Glaxo Group Ltd	Heterocyclic compounds
IT1170387B (it) *	1982-06-07	1987-06-03	Glaxo Group Ltd	Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
GB8332434D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Production of chemical compounds
GB8332435D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Chemical compounds

1984
- 1984-08-01 GB GB848419575A patent/GB8419575D0/en active Pending
1985
- 1985-07-26 GR GR851850A patent/GR851850B/el unknown
- 1985-07-30 CH CH3296/85A patent/CH666026A5/fr not_active IP Right Cessation
- 1985-07-30 JO JO19851379A patent/JO1379B1/en active
- 1985-07-31 IS IS3034A patent/IS1430B6/is unknown
- 1985-07-31 HU HU852945A patent/HU201738B/hu unknown
- 1985-08-01 PH PH32599A patent/PH22850A/en unknown
- 1985-08-01 PT PT80900A patent/PT80900B/pt unknown
- 1985-08-01 JP JP60168664A patent/JPH0623197B2/ja not_active Expired - Lifetime
- 1985-08-01 NZ NZ212948A patent/NZ212948A/xx unknown
- 1985-08-01 KR KR1019850005553A patent/KR930003759B1/ko not_active IP Right Cessation
- 1985-08-01 ES ES545810A patent/ES8700234A1/es not_active Expired
- 1985-08-01 MA MA20725A patent/MA20499A1/fr unknown
- 1985-08-01 CA CA000487992A patent/CA1241004A/en not_active Expired
- 1985-08-01 UA UA3935745A patent/UA6329A1/uk unknown
- 1985-08-01 ZW ZW124/85A patent/ZW12485A1/xx unknown
- 1985-08-01 EG EG460/85A patent/EG17283A/xx active
- 1985-08-01 LU LU86032A patent/LU86032A1/fr active Protection Beyond IP Right Term
- 1985-08-01 AT AT0226685A patent/AT386196B/de not_active IP Right Cessation
- 1985-08-01 PL PL1985254800A patent/PL146005B1/pl unknown
- 1985-08-01 BE BE0/215426A patent/BE903006A/fr not_active IP Right Cessation
- 1985-08-01 AU AU45689/85A patent/AU573878B2/en not_active Expired
- 1985-08-01 FI FI852969A patent/FI78466C/fi not_active IP Right Cessation
- 1985-08-01 IT IT8548435A patent/IT1207325B/it active Protection Beyond IP Right Term
- 1985-08-01 LU LU88266C patent/LU88266I2/xx unknown
- 1985-08-01 FR FR8511790A patent/FR2568571B1/fr not_active Expired
- 1985-08-01 IL IL75986A patent/IL75986A/xx not_active IP Right Cessation
- 1985-08-01 DK DK351185A patent/DK158942C/da not_active IP Right Cessation
- 1985-08-01 SE SE8503680A patent/SE452460B/sv not_active IP Right Cessation
- 1985-08-01 ZA ZA855818A patent/ZA855818B/xx unknown
- 1985-08-01 NL NLAANVRAGE8502171,A patent/NL188642C/xx not_active IP Right Cessation
- 1985-08-01 DE DE19853527648 patent/DE3527648A1/de active Granted
- 1985-08-01 NO NO853046A patent/NO164653C/no not_active IP Right Cessation
- 1985-08-01 IE IE191885A patent/IE58122B1/en not_active IP Right Cessation
- 1985-08-01 SU SU853935745A patent/SU1498386A3/ru active
- 1985-08-01 MX MX8273A patent/MX159672A/es unknown
1986
- 1986-02-14 ES ES552047A patent/ES8801204A1/es not_active Expired
- 1986-10-22 PH PH34399A patent/PH24117A/en unknown
1987
- 1987-03-31 ES ES557483A patent/ES8801790A1/es not_active Expired
- 1987-03-31 ES ES557482A patent/ES8801900A1/es not_active Expired
- 1987-03-31 ES ES557480A patent/ES8801788A1/es not_active Expired
- 1987-03-31 ES ES557481A patent/ES8801789A1/es not_active Expired
1988
- 1988-12-16 MX MX1422188A patent/MX14221A/es unknown
1989
- 1989-02-07 KE KE3858A patent/KE3858A/xx unknown
- 1989-03-01 US US07/317,682 patent/US5037845A/en not_active Expired - Lifetime
- 1989-04-20 HK HK332/89A patent/HK33289A/xx not_active IP Right Cessation
- 1989-11-17 DO DO1989004759A patent/DOP1989004759A/es unknown
1991
- 1991-12-23 SK SK4041-91A patent/SK404191A3/sk unknown
- 1991-12-23 CZ CS914041A patent/CZ280530B6/cs not_active IP Right Cessation
1993
- 1993-06-11 NL NL930065C patent/NL930065I2/nl unknown
1994
- 1994-05-26 EC EC1994001096A patent/ECSP941096A/es unknown
- 1994-11-09 NO NO1994023C patent/NO1994023I1/no unknown

Also Published As

Publication number	Publication date
ES8801789A1 (es)	1988-02-16
IS1430B6 (is)	1990-07-16
ES8801790A1 (es)	1988-02-16
IL75986A (en)	1989-02-28
PH22850A (en)	1989-01-19
ES8801900A1 (es)	1988-03-01
JO1379B1 (en)	1986-11-30
IE58122B1 (en)	1993-07-14
ES8801788A1 (es)	1988-02-16
PH24117A (en)	1990-03-05
NO164653B (no)	1990-07-23
ES557482A0 (es)	1988-03-01
KR930003759B1 (ko)	1993-05-10
SU1498386A3 (ru)	1989-07-30
US5037845A (en)	1991-08-06
DK351185D0 (da)	1985-08-01
FR2568571B1 (fr)	1988-09-23
JPH0623197B2 (ja)	1994-03-30
FI852969A0 (fi)	1985-08-01
CA1241004A (en)	1988-08-23
BE903006A (fr)	1986-02-03
HUT40077A (en)	1986-11-28
LU86032A1 (fr)	1986-02-18
SK277952B6 (en)	1995-09-13
DK158942C (da)	1991-01-21
HU201738B (en)	1990-12-28
ES557481A0 (es)	1988-02-16
NO164653C (no)	1990-11-07
NL8502171A (nl)	1986-03-03
MA20499A1 (fr)	1986-04-01
LU88266I2 (da)	1994-02-03
GR851850B (da)	1985-11-26
CH666026A5 (fr)	1988-06-30
ES8700234A1 (es)	1986-10-16
ES552047A0 (es)	1987-12-16
FI852969L (fi)	1986-02-02
GB8419575D0 (en)	1984-09-05
IT8548435A0 (it)	1985-08-01
IE851918L (en)	1986-02-01
KR860001788A (ko)	1986-03-22
DOP1989004759A (es)	1999-02-06
ZW12485A1 (en)	1986-02-26
MX14221A (es)	1993-10-01
JPS6147464A (ja)	1986-03-07
SE452460B (sv)	1987-11-30
PL254800A1 (en)	1986-10-21
AT386196B (de)	1988-07-11
NO1994023I1 (no)	1994-11-09
ATA226685A (de)	1987-12-15
PT80900A (en)	1985-09-01
AU573878B2 (en)	1988-06-23
EG17283A (en)	1992-06-30
DK158942B (da)	1990-08-06
UA6329A1 (uk)	1994-12-29
IS3034A7 (is)	1986-02-02
NL188642C (nl)	1992-08-17
NL930065I2 (nl)	1993-10-01
IL75986A0 (en)	1985-12-31
PT80900B (pt)	1987-12-30
SK404191A3 (en)	1995-09-13
CZ404191A3 (en)	1993-04-14
CZ280530B6 (cs)	1996-02-14
FR2568571A1 (fr)	1986-02-07
FI78466C (fi)	1989-08-10
DE3527648A1 (de)	1986-02-13
DE3527648C2 (da)	1993-08-26
SE8503680D0 (sv)	1985-08-01
IT1207325B (it)	1989-05-17
FI78466B (fi)	1989-04-28
AU4568985A (en)	1986-02-06
ES557483A0 (es)	1988-02-16
ES545810A0 (es)	1986-10-16
KE3858A (en)	1989-06-02
ZA855818B (en)	1986-04-30
ES557480A0 (es)	1988-02-16
NL930065I1 (nl)	1993-09-01
ECSP941096A (es)	1995-01-16
PL146005B1 (en)	1988-12-31
HK33289A (en)	1989-04-28
NO853046L (no)	1986-02-03
MX159672A (es)	1989-08-02
NZ212948A (en)	1989-05-29
SE8503680L (sv)	1986-02-02
ES8801204A1 (es)	1987-12-16

Legal Events

Date

Code

Title

Description

1993-09-13

CTFF

Application for supplementary protection certificate (spc) filed

Free format text: PRODUCT NAME: SUMATRIPTANSUCCINAT

Spc suppl protection certif: CA 1993 00016

Filing date: 19930428

1994-12-05