NO167292C - PROCEDURE FOR THE PREPARATION OF CEFUROXIM 1 ACETOXYLYL ESTE. - Google Patents

PROCEDURE FOR THE PREPARATION OF CEFUROXIM 1 ACETOXYLYL ESTE.

Info

Publication number
NO167292C
NO167292C NO843055A NO843055A NO167292C NO 167292 C NO167292 C NO 167292C NO 843055 A NO843055 A NO 843055A NO 843055 A NO843055 A NO 843055A NO 167292 C NO167292 C NO 167292C
Authority
NO
Norway
Prior art keywords
acetoxylyl
cefuroxim
este
procedure
preparation
Prior art date
Application number
NO843055A
Other languages
Norwegian (no)
Other versions
NO167292B (en
NO843055L (en
Inventor
Harold Alfred Crisp
Michael Wright
John Peter Turnbull
John Francis Oughton
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO843055L publication Critical patent/NO843055L/en
Publication of NO167292B publication Critical patent/NO167292B/en
Publication of NO167292C publication Critical patent/NO167292C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO843055A 1983-07-29 1984-07-27 PROCEDURE FOR THE PREPARATION OF CEFUROXIM 1 ACETOXYLYL ESTE. NO167292C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838320521A GB8320521D0 (en) 1983-07-29 1983-07-29 Chemical process

Publications (3)

Publication Number Publication Date
NO843055L NO843055L (en) 1985-01-30
NO167292B NO167292B (en) 1991-07-15
NO167292C true NO167292C (en) 1991-10-23

Family

ID=10546505

Family Applications (1)

Application Number Title Priority Date Filing Date
NO843055A NO167292C (en) 1983-07-29 1984-07-27 PROCEDURE FOR THE PREPARATION OF CEFUROXIM 1 ACETOXYLYL ESTE.

Country Status (21)

Country Link
JP (1) JPH0613526B2 (en)
KR (1) KR910008377B1 (en)
AT (1) AT392470B (en)
AU (2) AU582121B2 (en)
BE (1) BE900241A (en)
CA (1) CA1265511A (en)
CH (1) CH662121A5 (en)
DE (1) DE3427828A1 (en)
DK (1) DK165505C (en)
ES (1) ES534695A0 (en)
FI (1) FI76808C (en)
FR (1) FR2549837B1 (en)
GB (2) GB8320521D0 (en)
IE (1) IE57726B1 (en)
IL (1) IL72536A (en)
NL (1) NL8402372A (en)
NO (1) NO167292C (en)
NZ (1) NZ209046A (en)
PT (1) PT78985B (en)
SE (1) SE463263B (en)
ZA (1) ZA845830B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
GB8524001D0 (en) * 1985-09-30 1985-11-06 Glaxo Group Ltd Pharmaceutical composition
US5063224A (en) * 1990-07-09 1991-11-05 Eli Lilly And Company R-cefuroxime axetil
IT1277426B1 (en) * 1995-08-03 1997-11-10 Acs Dobfar Spa BIOAVAILABLE CRYSTALLINE FORM OF CEFUROXIMA AXETIL
CN1111537C (en) * 1997-05-15 2003-06-18 第一制糖株式会社 The preparation method of highly pure crystalline form of cefuroxime axetil
KR100228264B1 (en) * 1997-08-02 1999-11-01 김선진 The synthetic method of crystalline cefuroxime axetil
CA2209868C (en) * 1997-08-15 2001-08-14 Bernard Charles Sherman Pharmaceutical compositions comprising cefuroxime axetil
IN186539B (en) * 1997-09-29 2001-09-29 Ranbaxy Lab Ltd
EP0937727B1 (en) * 1998-02-20 2002-01-30 Fako Ilaclari A.S. Process of preparation of soluble crystalline cefuroxime axetil
IN190849B (en) 2000-07-17 2003-08-23 Ranbaxy Lab Ltd
AT411996B (en) 2000-09-11 2004-08-26 Sandoz Ag METHOD FOR PRODUCING CEFUROXIME IN THE FORM OF ITS N-BUTYL LAMONIUM SALTS
ITMI20011763A1 (en) * 2001-08-10 2003-02-10 Antibioticos Spa HIGH-PURITY CEFUROXIME AXELITE PREPARATION PROCESS
ITMI20011925A1 (en) * 2001-09-14 2003-03-14 Antibioticos Spa METHOD APPLICABLE ON INDUSTRIAL SCALE FOR THE PREPARATION OF CEFUROXIME AXETILE CRISTALLINO
TWI328006B (en) * 2003-12-26 2010-08-01 Nissan Chemical Ind Ltd Crystal form of quinoline compound and process for its production
CN100448879C (en) * 2004-07-22 2009-01-07 北京化工大学 Method for preparing unformed cefuroxime axetil
DE102005019458A1 (en) 2005-04-25 2006-10-26 Grünenthal GmbH Composition, useful in the preparation of pellets and the multi-particular-presentation form, comprises cefuroximaxetil and carrageenan of the group of lambda carrageenan, tau carrageenan and kappa carrageenan

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1094545A (en) * 1976-02-16 1981-01-27 Michael Gregson Cephalosporin antibiotics
GB1571683A (en) * 1976-02-16 1980-07-16 Glaxo Operations Ltd Ester derivatives of cefuroxime
GB1598568A (en) * 1977-04-19 1981-09-23 Glaxo Lab Ltd Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid
JPS577485A (en) * 1980-06-13 1982-01-14 Takeda Chem Ind Ltd Cephalosporin
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics

Also Published As

Publication number Publication date
DK366684A (en) 1985-01-30
AU582121B2 (en) 1989-03-16
FI843011A (en) 1985-01-30
GB2145409B (en) 1987-02-18
ZA845830B (en) 1986-03-26
IE841938L (en) 1985-01-29
NO167292B (en) 1991-07-15
SE463263B (en) 1990-10-29
PT78985B (en) 1986-10-23
KR910008377B1 (en) 1991-10-12
GB8320521D0 (en) 1983-09-01
FR2549837B1 (en) 1986-12-26
NZ209046A (en) 1988-02-29
KR850001221A (en) 1985-03-16
FI76808C (en) 1988-12-12
FR2549837A1 (en) 1985-02-01
AU3660189A (en) 1989-10-05
IL72536A (en) 1988-01-31
IL72536A0 (en) 1984-11-30
AT392470B (en) 1991-04-10
BE900241A (en) 1985-01-28
DK165505B (en) 1992-12-07
PT78985A (en) 1984-08-01
DK366684D0 (en) 1984-07-27
JPS6075484A (en) 1985-04-27
IE57726B1 (en) 1993-03-24
AU634965B2 (en) 1993-03-11
ES8601869A1 (en) 1985-11-01
ATA244484A (en) 1990-09-15
GB2145409A (en) 1985-03-27
GB8419202D0 (en) 1984-08-30
DK165505C (en) 1993-04-19
CH662121A5 (en) 1987-09-15
DE3427828A1 (en) 1985-02-14
FI76808B (en) 1988-08-31
SE8403897D0 (en) 1984-07-27
NO843055L (en) 1985-01-30
SE8403897L (en) 1985-01-30
NL8402372A (en) 1985-02-18
JPH0613526B2 (en) 1994-02-23
ES534695A0 (en) 1985-11-01
FI843011A0 (en) 1984-07-27
AU3125684A (en) 1985-01-31
CA1265511A (en) 1990-02-06

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Free format text: LAPSED IN JANUARY 2003