NL8002126A - 7-/2-(2-amino-4-thiazolyl)-2-(1-carboxy-1,1-dialkyl)- -alkoxy-imino/aceetamido/cefem-sulfoxyden. - Google Patents

7-/2-(2-amino-4-thiazolyl)-2-(1-carboxy-1,1-dialkyl)- -alkoxy-imino/aceetamido/cefem-sulfoxyden. Download PDF

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Publication number
NL8002126A
NL8002126A NL8002126A NL8002126A NL8002126A NL 8002126 A NL8002126 A NL 8002126A NL 8002126 A NL8002126 A NL 8002126A NL 8002126 A NL8002126 A NL 8002126A NL 8002126 A NL8002126 A NL 8002126A
Authority
NL
Netherlands
Prior art keywords
aceetamido
cefem
sulfoxides
imino
thiazolyl
Prior art date
Application number
NL8002126A
Other languages
English (en)
Dutch (nl)
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of NL8002126A publication Critical patent/NL8002126A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL8002126A 1979-04-12 1980-04-11 7-/2-(2-amino-4-thiazolyl)-2-(1-carboxy-1,1-dialkyl)- -alkoxy-imino/aceetamido/cefem-sulfoxyden. NL8002126A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/029,417 US4237128A (en) 1979-04-12 1979-04-12 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides

Publications (1)

Publication Number Publication Date
NL8002126A true NL8002126A (nl) 1980-10-14

Family

ID=21848908

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8002126A NL8002126A (nl) 1979-04-12 1980-04-11 7-/2-(2-amino-4-thiazolyl)-2-(1-carboxy-1,1-dialkyl)- -alkoxy-imino/aceetamido/cefem-sulfoxyden.

Country Status (20)

Country Link
US (1) US4237128A (xx)
JP (1) JPS55141489A (xx)
AU (1) AU538177B2 (xx)
BE (1) BE882758A (xx)
CA (1) CA1147323A (xx)
CH (1) CH653035A5 (xx)
DE (1) DE3013966A1 (xx)
DK (1) DK157580A (xx)
FR (1) FR2465737A1 (xx)
GB (1) GB2049675B (xx)
HU (1) HU182686B (xx)
IE (1) IE49657B1 (xx)
IT (1) IT1149833B (xx)
LU (1) LU82352A1 (xx)
NL (1) NL8002126A (xx)
NO (1) NO801052L (xx)
NZ (1) NZ193317A (xx)
PH (4) PH15386A (xx)
SE (1) SE8002769L (xx)
ZA (1) ZA801787B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
AR229882A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para preparar antibioticos de cefalosporina
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
IE49211B1 (en) * 1978-11-17 1985-08-21 Glaxo Group Ltd Cephalosporin antibiotics
US4275062A (en) * 1979-09-19 1981-06-23 E. R. Squibb & Sons, Inc. Aminothiazolyl ureido sulfoxide cephalosporins
FR2501209B1 (fr) * 1981-03-03 1986-07-04 Sanofi Sa Nouveaux derives des cephalosporines et medicaments antibiotiques contenant lesdits derives
GR75706B (xx) * 1980-06-30 1984-08-02 Sanofi Sa
DE3045805A1 (de) 1980-12-05 1982-07-08 Basf Ag, 6700 Ludwigshafen Diphenylether, verfahren zu ihrer herstellung und ihre verwendung als herbizide
US4336253A (en) * 1981-03-11 1982-06-22 Eli Lilly And Company Cephalosporin antibiotics
JPS5859991A (ja) * 1981-09-14 1983-04-09 Fujisawa Pharmaceut Co Ltd 新規セフェム化合物
FR2516515A1 (fr) * 1981-11-16 1983-05-20 Sanofi Sa Nouveaux derives de pyridinium thiomethyl cephalosporines, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2517309A1 (fr) * 1981-12-01 1983-06-03 Sanofi Sa Nouveaux derives de cephalosporines substitues en position 3 par un groupe heterocycle thiomethyl; procede de preparation desdits composes et compositions pharmaceutiques en contenant
US4394503A (en) * 1981-12-07 1983-07-19 Bristol-Myers Company Cephalosporin derivatives
US4474954A (en) * 1981-12-07 1984-10-02 Bristol-Myers Company Intermediates for cephalosporin derivatives
US4704457A (en) * 1982-06-21 1987-11-03 E. R. Squibb & Sons, Inc. Process for the preparation of (3S)-3-[[[2-(protected amino)-4-thiazolyl]-oxoacetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof
US4783443A (en) * 1986-03-03 1988-11-08 The University Of Chicago Amino acyl cephalosporin derivatives
BRPI0413908A (pt) * 2003-08-25 2006-10-24 Revaax Pharmaceuticals Llc formulação farmacêutica neuroterapêutica em forma de dosagem oral, composto, e, método de tratamento de um distúrbio comportamental ou um distúrbio cognitivo

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641014A (en) * 1968-10-03 1972-02-08 Lilly Co Eli Reduction of delta**3-cephalosporin sulfoxides
US3971778A (en) * 1972-05-12 1976-07-27 Glaxo Laboratories Limited Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position
US4138555A (en) * 1971-05-14 1979-02-06 Glaxo Laboratories, Limited (6R,7R)-7-[2-aryl-2-(etherified oximino)acetamido]-3-carbamoyloxymethylceph-3-em-4-carboxylic acid 1-oxides
US4092477A (en) * 1971-05-14 1978-05-30 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins
US4075337A (en) * 1972-07-18 1978-02-21 Gist-Brocades N.V. Methods of combatting bacterial infections in warm-blooded animal with cephalsporin R-sulfoxide
US4084049A (en) * 1972-10-20 1978-04-11 Fujisawa Pharmaceutical Co., Ltd. Cepham derivatives
US4095021A (en) * 1973-12-21 1978-06-13 Glaxo Laboratories Limited 3-Carbamoyloxymethyl or N-methyl-carbamoyloxymethyl-7-[2-carboxymethoxyimino-2-(fur-2-yl or thien-2-yl)acetamido]ceph-3-em-4-carboxylic acids and derivatives thereof
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
SE439312B (sv) 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
AR229883A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
NL7904125A (nl) * 1978-05-26 1979-11-28 Glaxo Group Ltd Cefalosporineverbindingen.
NZ190556A (en) * 1978-05-26 1982-05-25 Glaxo Group Ltd Cephalosporin antibiotics and pharmaceutical compositions
AR229882A1 (es) * 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para preparar antibioticos de cefalosporina

Also Published As

Publication number Publication date
IT8021343A0 (it) 1980-04-11
NZ193317A (en) 1984-04-27
DE3013966A1 (de) 1980-11-20
CA1147323A (en) 1983-05-31
BE882758A (fr) 1980-10-13
IE800669L (en) 1980-10-12
IE49657B1 (en) 1985-11-13
FR2465737A1 (fr) 1981-03-27
CH653035A5 (de) 1985-12-13
HU182686B (en) 1984-02-28
FR2465737B1 (xx) 1984-04-27
PH19111A (en) 1986-01-06
US4237128A (en) 1980-12-02
LU82352A1 (fr) 1980-12-16
IT1149833B (it) 1986-12-10
ZA801787B (en) 1981-03-25
DK157580A (da) 1980-10-13
SE8002769L (sv) 1980-12-12
PH18939A (en) 1985-11-14
AU538177B2 (en) 1984-08-02
GB2049675A (en) 1980-12-31
PH17514A (en) 1984-09-07
PH15386A (en) 1982-12-23
NO801052L (no) 1980-10-13
AU5695380A (en) 1980-10-16
JPS55141489A (en) 1980-11-05
GB2049675B (en) 1983-05-18

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BV The patent application has lapsed