NL7708741A - Werkwijze ter bereiding van prostaanzuurderiva- ten alsmede farmaceutische preparaten die deze derivaten als actieve component bevatten. - Google Patents

Werkwijze ter bereiding van prostaanzuurderiva- ten alsmede farmaceutische preparaten die deze derivaten als actieve component bevatten.

Info

Publication number
NL7708741A
NL7708741A NL7708741A NL7708741A NL7708741A NL 7708741 A NL7708741 A NL 7708741A NL 7708741 A NL7708741 A NL 7708741A NL 7708741 A NL7708741 A NL 7708741A NL 7708741 A NL7708741 A NL 7708741A
Authority
NL
Netherlands
Prior art keywords
derivatives
preparation
active component
pharmaceutical preparations
preparations containing
Prior art date
Application number
NL7708741A
Other languages
English (en)
Dutch (nl)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NL7708741A publication Critical patent/NL7708741A/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/535—Organo-phosphoranes
    • C07F9/5352—Phosphoranes containing the structure P=C-

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Ink Jet (AREA)
  • Materials For Photolithography (AREA)
  • Polarising Elements (AREA)
NL7708741A 1976-08-06 1977-08-08 Werkwijze ter bereiding van prostaanzuurderiva- ten alsmede farmaceutische preparaten die deze derivaten als actieve component bevatten. NL7708741A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762635985 DE2635985A1 (de) 1976-08-06 1976-08-06 Prostansaeurederivat und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
NL7708741A true NL7708741A (nl) 1978-02-08

Family

ID=5985150

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7708741A NL7708741A (nl) 1976-08-06 1977-08-08 Werkwijze ter bereiding van prostaanzuurderiva- ten alsmede farmaceutische preparaten die deze derivaten als actieve component bevatten.

Country Status (12)

Country Link
US (3) US4284646A (da)
JP (1) JPS5340740A (da)
BE (1) BE857541A (da)
CH (2) CH637376A5 (da)
DE (1) DE2635985A1 (da)
DK (1) DK334577A (da)
FR (1) FR2392971A1 (da)
GB (1) GB1590654A (da)
IE (1) IE45863B1 (da)
IT (1) IT1085354B (da)
LU (1) LU77916A1 (da)
NL (1) NL7708741A (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1078774B (it) * 1976-09-07 1985-05-08 Lpb Ist Farm Derivato dell acido 19 metil 9 cheto 15 idrossi prost 18 enoico
US4257983A (en) * 1979-04-02 1981-03-24 The Upjohn Company 2-Decarboxy-2-aminomethyl-19,20-didehydro-PG1 compounds
US4257981A (en) * 1979-04-02 1981-03-24 The Upjohn Company 2-Decarboxy-2-aminomethyl-19,20-didehydro-PG2 compounds
US4276427A (en) * 1979-04-02 1981-06-30 The Upjohn Company 19,20-Didehydro-PG1 compounds
US4259529A (en) * 1979-04-02 1981-03-31 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-19,20-didehydro-13,14-dihydro-PG1 compounds
US4257982A (en) * 1979-04-02 1981-03-24 The Upjohn Company 2-Decarboxy-2-aminomethyl-19,20-didehydro-13,14-dihydro-PG2 compounds
US4276428A (en) * 1979-04-02 1981-06-30 The Upjohn Company 19,20-Didehydro-13,14-dihydro-PG1 compounds
US4284795A (en) * 1979-04-02 1981-08-18 The Upjohn Company 19,20-Didehydro-PG2 compounds
US4257980A (en) * 1979-04-02 1981-03-24 The Upjohn Company 2-Decarboxy-2-aminomethyl-19,20-didehydro-13,14-dihydro-PG1 compounds
US4243611A (en) * 1979-04-02 1981-01-06 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-19,20-didehydro PG2 compounds
US4269995A (en) * 1979-04-02 1981-05-26 The Upjohn Company 19,20-Didehydro-13,14-dihydro-PG2 compounds
US4257979A (en) * 1979-04-02 1981-03-24 The Upjohn Company 2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-PG compounds
US4278818A (en) * 1979-04-02 1981-07-14 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-19,20-didehydro-13,14-dihydro-PG2 compounds
US4251463A (en) * 1979-05-01 1981-02-17 The Upjohn Company 2-Decarboxy-2-aminomethyl-9-deoxy-9-methylene-5,6-didehydro-PGF1 compounds
US4254058A (en) * 1979-07-05 1981-03-03 The Upjohn Company 2-Decarboxy-2-aminomethyl-19-hydroxy-6a-carba-PGI2 compounds
US4256667A (en) * 1979-07-05 1981-03-17 The Upjohn Company 2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6a-carba-PGI2 compounds
US4251464A (en) * 1979-07-05 1981-02-17 The Upjohn Company 2-Decarboxy-2-aminomethyl-19-hydroxy-6-oxo-PGE1 compounds
US4255354A (en) * 1979-07-05 1981-03-10 The Upjohn Company 2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6-oxo-PGF1 compounds
FI71308C (fi) * 1981-02-13 1986-12-19 Schering Ag Analogifoerfarande foer framstaellning av terapeutiskt anvaendbara (13e)-(8r,11r,12r)-11,15-dihydroxi-16,19-dimetyl-9-oxo-13,18-prostadiensyraderivat och av deras salter
CA2109109A1 (en) * 1991-04-22 1992-10-23 Fumie Sato Prostaglandin e1 analogues
CA2088128C (en) * 1992-01-31 2002-10-29 Katsuhiro Imaki Salts of glucopyranose derivatives and its intermediate
US5545665A (en) 1993-12-28 1996-08-13 Allergan Cyclopentane(ene) heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
JP4834224B2 (ja) 1999-03-05 2011-12-14 デューク ユニバーシティ Ｃ１６不飽和ｆｐ−選択的プロスタグランジン類縁体
US6894175B1 (en) * 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20090148527A1 (en) * 2007-12-07 2009-06-11 Robinson Michael R Intraocular formulation
US8722739B2 (en) * 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) * 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US10486881B2 (en) 2016-12-09 2019-11-26 Fres-Co System Usa, Inc. Flexible packages with clog resistant degassing valve and methods of making the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3419285A (en) * 1967-05-02 1968-12-31 Earl P. Morehouse Towing hitch
US3919285A (en) * 1971-02-02 1975-11-11 Upjohn Co PGE{HD 3 {B analogs
US3932479A (en) * 1973-04-27 1976-01-13 American Cyanamid Company Lithium 3-triphenylmethoxy-1-trans-alkenyl-dialkyl alanates
US4064351A (en) * 1974-09-19 1977-12-20 Sankyo Company Limited 9-OXO-15 ξ-HYDROXY-20-ALKYLIDENEPROST-13(TRANS)-ENOIC ACID DERIVATIVES
GB1499018A (en) * 1974-09-19 1978-01-25 Sankyo Co Pharmaceutically useful prostenoic acid derivatives
IT1078774B (it) * 1976-09-07 1985-05-08 Lpb Ist Farm Derivato dell acido 19 metil 9 cheto 15 idrossi prost 18 enoico

Also Published As

Publication number Publication date
BE857541A (fr) 1978-02-06
IE45863L (en) 1978-02-06
US4359467A (en) 1982-11-16
FR2392971B1 (da) 1980-02-15
CH637376A5 (de) 1983-07-29
JPS5340740A (en) 1978-04-13
FR2392971A1 (fr) 1978-12-29
US4489092A (en) 1984-12-18
LU77916A1 (da) 1977-11-14
CH641158A5 (de) 1984-02-15
IE45863B1 (en) 1982-12-15
DK334577A (da) 1978-02-07
IT1085354B (it) 1985-05-28
US4284646A (en) 1981-08-18
GB1590654A (en) 1981-06-03
DE2635985A1 (de) 1978-02-09

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BB A search report has been drawn up
A85 Still pending on 85-01-01
BV The patent application has lapsed