NL192740B - Oxadethiacefalosporinederivaat met antibacteriële werking, alsmede bereidingswijze daarvoor en antibacteriaal preparaat daaruit. - Google Patents

Oxadethiacefalosporinederivaat met antibacteriële werking, alsmede bereidingswijze daarvoor en antibacteriaal preparaat daaruit.

Info

Publication number
NL192740B
NL192740B NL8304409A NL8304409A NL192740B NL 192740 B NL192740 B NL 192740B NL 8304409 A NL8304409 A NL 8304409A NL 8304409 A NL8304409 A NL 8304409A NL 192740 B NL192740 B NL 192740B
Authority
NL
Netherlands
Prior art keywords
preparation
antibacterial
oxadethiacephalosporin
derivative
well
Prior art date
Application number
NL8304409A
Other languages
English (en)
Other versions
NL192740C (nl
NL8304409A (nl
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of NL8304409A publication Critical patent/NL8304409A/nl
Publication of NL192740B publication Critical patent/NL192740B/nl
Application granted granted Critical
Publication of NL192740C publication Critical patent/NL192740C/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D505/00Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
NL8304409A 1982-12-23 1983-12-22 Oxadethiacefalosporinederivaat met antibacteriële werking, alsmede bereidingswijze daarvoor en antibacteriaal preparaat daaruit. NL192740C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP57234472A JPS59139385A (ja) 1982-12-23 1982-12-23 フルオロメチルチオオキサセフアロスポリン
JP23447282 1982-12-23

Publications (3)

Publication Number Publication Date
NL8304409A NL8304409A (nl) 1984-07-16
NL192740B true NL192740B (nl) 1997-09-01
NL192740C NL192740C (nl) 1998-01-06

Family

ID=16971542

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8304409A NL192740C (nl) 1982-12-23 1983-12-22 Oxadethiacefalosporinederivaat met antibacteriële werking, alsmede bereidingswijze daarvoor en antibacteriaal preparaat daaruit.

Country Status (26)

Country Link
US (1) US4532233A (nl)
JP (1) JPS59139385A (nl)
KR (1) KR890000095B1 (nl)
AT (1) AT383807B (nl)
AU (1) AU558547B2 (nl)
BE (1) BE898541A (nl)
CA (1) CA1236099A (nl)
CH (1) CH656619A5 (nl)
DE (1) DE3345989A1 (nl)
DK (1) DK159447C (nl)
ES (6) ES8506024A1 (nl)
FI (1) FI74016C (nl)
FR (1) FR2538391B1 (nl)
GB (1) GB2132198B (nl)
HK (1) HK89988A (nl)
HU (1) HU189014B (nl)
IE (1) IE56401B1 (nl)
IL (1) IL70488A (nl)
IT (1) IT1160238B (nl)
NL (1) NL192740C (nl)
NO (1) NO167740C (nl)
NZ (1) NZ206413A (nl)
PH (1) PH19352A (nl)
PT (1) PT77831B (nl)
SE (2) SE461527B (nl)
ZA (1) ZA838920B (nl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045514A (ja) * 1983-08-22 1985-03-12 Shionogi & Co Ltd 安定な抗菌性凍結乾燥製剤
JP2004168775A (ja) * 2002-11-08 2004-06-17 Orchid Chemicals & Pharmaceuticals Ltd オキサセファロスポリンの改良合成法
JP4530287B2 (ja) * 2004-02-20 2010-08-25 塩野義製薬株式会社 オキサセフェムの結晶
EP1996595A2 (en) * 2006-03-15 2008-12-03 CARTHESIA s.a.s. DI EMANUELA MIGLIAVACCA & C. PROCESS FOR THE PREPARATION OF (1-OXA- OR l-THIA-)3- CEPHEM DERIVATIVES AND RELATED INTERMEDIATES
CN102952149B (zh) * 2012-11-09 2015-06-24 浙江新和成股份有限公司 一种氟氧头孢中间体的一锅合成法
KR101314500B1 (ko) * 2012-12-28 2013-10-07 제일약품주식회사 안정성이 개선된 옥사세펨 제제 및 그 제조방법
CN103524534B (zh) * 2013-09-02 2016-08-17 上海龙翔生物医药开发有限公司 氟氧头孢钠的制备方法
CN104327100B (zh) * 2014-09-30 2016-09-28 华北制药河北华民药业有限责任公司 高纯度氟氧头孢钠制备工艺
CN105399755B (zh) * 2015-11-03 2018-05-11 浙江永宁药业股份有限公司 一种氟氧头孢酸的合成方法
CN105801601B (zh) * 2016-04-02 2018-01-26 丽珠医药集团股份有限公司 一种氟氧头孢钠合成方法
CN108424418A (zh) * 2017-02-15 2018-08-21 山东致纯医药科技有限公司 一种氟氧头孢钠杂质
KR102115644B1 (ko) * 2017-09-13 2020-05-27 주식회사 동도물산 7α-알콕시옥사세펨 중간체의 제조방법
CN110028522A (zh) * 2019-04-22 2019-07-19 山西千岫制药有限公司 一种氟氧头孢母核的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5419990A (en) * 1977-07-14 1979-02-15 Shionogi & Co Ltd Dihydrotriazinylthioxacephalosporin
JPS5690088A (en) * 1979-11-02 1981-07-21 Meiji Seika Kaisha Ltd Novel cephalosporin analog compound
JPS56103185A (en) * 1980-01-22 1981-08-18 Shionogi & Co Ltd Malonamidoxa-dethia-cephem compound

Also Published As

Publication number Publication date
DK159447C (da) 1991-04-08
ES534290A0 (es) 1985-06-01
CH656619A5 (de) 1986-07-15
BE898541A (fr) 1984-04-16
KR890000095B1 (ko) 1989-03-07
ES8708227A1 (es) 1987-10-01
FI834682A0 (fi) 1983-12-19
FR2538391A1 (fr) 1984-06-29
ES534289A0 (es) 1985-06-01
SE8802008D0 (sv) 1988-05-30
NO167740B (no) 1991-08-26
NL192740C (nl) 1998-01-06
AU2211383A (en) 1984-06-28
AU558547B2 (en) 1987-02-05
IT1160238B (it) 1987-03-04
HUT34200A (en) 1985-02-28
DK589583A (da) 1984-06-24
JPS59139385A (ja) 1984-08-10
ES8505670A1 (es) 1985-06-01
ES534291A0 (es) 1987-02-16
IE832951L (en) 1984-06-23
DK589583D0 (da) 1983-12-21
FI74016B (fi) 1987-08-31
NL8304409A (nl) 1984-07-16
ES534288A0 (es) 1985-06-01
GB2132198A (en) 1984-07-04
ES556846A0 (es) 1987-10-01
IL70488A (en) 1988-03-31
HU189014B (en) 1986-06-30
GB2132198B (en) 1986-10-01
DE3345989C2 (nl) 1992-09-24
ES527595A0 (es) 1985-06-16
PT77831B (en) 1986-03-26
ES8505671A1 (es) 1985-06-01
ATA446883A (de) 1987-01-15
NO167740C (no) 1991-12-04
ES8703458A1 (es) 1987-02-16
IL70488A0 (en) 1984-03-30
AT383807B (de) 1987-08-25
FI834682A (fi) 1984-06-24
ES8506024A1 (es) 1985-06-16
PH19352A (en) 1986-04-02
FI74016C (fi) 1987-12-10
CA1236099A (en) 1988-05-03
NZ206413A (en) 1986-05-09
SE8802008L (sv) 1988-05-30
PT77831A (en) 1984-01-01
HK89988A (en) 1988-11-11
ES8505672A1 (es) 1985-06-01
FR2538391B1 (fr) 1986-12-19
JPS6225671B2 (nl) 1987-06-04
IE56401B1 (en) 1991-07-17
US4532233A (en) 1985-07-30
GB8333186D0 (en) 1984-01-18
NO834729L (no) 1984-06-25
DK159447B (da) 1990-10-15
IT8368343A0 (it) 1983-12-22
SE8307079D0 (sv) 1983-12-21
KR840007007A (ko) 1984-12-04
SE470132B (sv) 1993-11-15
SE461527B (sv) 1990-02-26
DE3345989A1 (de) 1984-06-28
CA1259989C (nl) 1989-09-26
ZA838920B (en) 1984-07-25
SE8307079L (sv) 1984-06-24

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20031222