NI202000050A - Anticuerpos de cadena pesada que se unen a cd22 - Google Patents

Anticuerpos de cadena pesada que se unen a cd22

Info

Publication number
NI202000050A
NI202000050A NI202000050A NI202000050A NI202000050A NI 202000050 A NI202000050 A NI 202000050A NI 202000050 A NI202000050 A NI 202000050A NI 202000050 A NI202000050 A NI 202000050A NI 202000050 A NI202000050 A NI 202000050A
Authority
NI
Nicaragua
Prior art keywords
heavy chain
joining
chain antibodies
antibodies
compositions
Prior art date
Application number
NI202000050A
Other languages
English (en)
Inventor
Force Aldred Shelley
Van Schooten Wim
Anne N Ogana Heather
Marie Davison Laura
Harris Katherine
Rangaswamy Udaya
D Trinklein Nathan
Original Assignee
Teneobio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teneobio Inc filed Critical Teneobio Inc
Publication of NI202000050A publication Critical patent/NI202000050A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/522—CH1 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Se describen anticuerpos anti-CD22 de cadena pesada (p. ej., UniAbsTM) junto con método para elaborar dichos anticuerpos, composiciones, incluidas las composiciones farmacéuticas que comprenden dichos anticuerpos, y su uso para tratar trastornos de linfocitos B que se caracterizan por la expresión de CD22.
NI202000050A 2017-12-22 2020-06-22 Anticuerpos de cadena pesada que se unen a cd22 NI202000050A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762609759P 2017-12-22 2017-12-22

Publications (1)

Publication Number Publication Date
NI202000050A true NI202000050A (es) 2020-12-04

Family

ID=65041936

Family Applications (1)

Application Number Title Priority Date Filing Date
NI202000050A NI202000050A (es) 2017-12-22 2020-06-22 Anticuerpos de cadena pesada que se unen a cd22

Country Status (21)

Country Link
US (2) US11873336B2 (es)
EP (1) EP3728319A1 (es)
JP (2) JP7486421B2 (es)
KR (1) KR20200104342A (es)
CN (1) CN111683966B (es)
AU (1) AU2018392088A1 (es)
BR (1) BR112020012554A2 (es)
CA (1) CA3086665A1 (es)
CL (2) CL2020001703A1 (es)
CO (1) CO2020008925A2 (es)
CR (1) CR20200322A (es)
EA (1) EA202091557A1 (es)
EC (1) ECSP20042489A (es)
IL (1) IL275498A (es)
JO (1) JOP20200157A1 (es)
MX (1) MX2020006494A (es)
NI (1) NI202000050A (es)
PE (1) PE20201171A1 (es)
PH (1) PH12020550964A1 (es)
SG (1) SG11202005880XA (es)
WO (1) WO2019126756A1 (es)

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CA3029209A1 (en) 2016-06-21 2017-12-28 Teneobio, Inc. Cd3 binding antibodies
BR112019004873A2 (pt) 2016-09-14 2019-06-11 Teneobio Inc anticorpos de ligação a cd3
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EP3728319A1 (en) 2017-12-22 2020-10-28 TeneoBio, Inc. Heavy chain antibodies binding to cd22
WO2020252366A1 (en) 2019-06-14 2020-12-17 Teneobio, Inc. Multispecific heavy chain antibodies binding to cd22 and cd3
KR20210143097A (ko) * 2020-05-19 2021-11-26 (주)이노베이션바이오 Cd22에 특이적인 항체 및 이의 용도
US20230250184A1 (en) * 2020-07-16 2023-08-10 Nanjing Legend Biotech Co., Ltd. Cd22 binding molecules and uses thereof

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Also Published As

Publication number Publication date
EP3728319A1 (en) 2020-10-28
EA202091557A1 (ru) 2020-11-18
AU2018392088A2 (en) 2020-08-27
ECSP20042489A (es) 2020-11-30
CL2022002247A1 (es) 2023-02-24
WO2019126756A1 (en) 2019-06-27
CN111683966A (zh) 2020-09-18
PH12020550964A1 (en) 2021-03-22
AU2018392088A1 (en) 2020-08-13
CR20200322A (es) 2021-01-12
US11873336B2 (en) 2024-01-16
WO2019126756A9 (en) 2019-10-17
IL275498A (en) 2020-08-31
CN111683966B (zh) 2023-07-11
RU2020124188A (ru) 2022-01-24
CL2020001703A1 (es) 2020-11-06
JP7486421B2 (ja) 2024-05-17
US20240117046A1 (en) 2024-04-11
JOP20200157A1 (ar) 2022-10-30
CO2020008925A2 (es) 2020-10-30
JP2021506325A (ja) 2021-02-22
BR112020012554A2 (pt) 2020-11-24
MX2020006494A (es) 2020-11-24
CA3086665A1 (en) 2019-06-27
PE20201171A1 (es) 2020-10-28
US20210095022A1 (en) 2021-04-01
KR20200104342A (ko) 2020-09-03
SG11202005880XA (en) 2020-07-29
JP2024062992A (ja) 2024-05-10

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