MY8700055A - 10 - alknyl steroids - Google Patents

10 - alknyl steroids

Info

Publication number
MY8700055A
MY8700055A MY55/87A MY8700055A MY8700055A MY 8700055 A MY8700055 A MY 8700055A MY 55/87 A MY55/87 A MY 55/87A MY 8700055 A MY8700055 A MY 8700055A MY 8700055 A MY8700055 A MY 8700055A
Authority
MY
Malaysia
Prior art keywords
alknyl
steroids
alknyl steroids
Prior art date
Application number
MY55/87A
Other languages
English (en)
Inventor
Brian W Metcalf
J O Neal Johnston
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of MY8700055A publication Critical patent/MY8700055A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MY55/87A 1980-06-27 1987-12-30 10 - alknyl steroids MY8700055A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16345180A 1980-06-27 1980-06-27

Publications (1)

Publication Number Publication Date
MY8700055A true MY8700055A (en) 1987-12-31

Family

ID=22590066

Family Applications (1)

Application Number Title Priority Date Filing Date
MY55/87A MY8700055A (en) 1980-06-27 1987-12-30 10 - alknyl steroids

Country Status (23)

Country Link
US (1) US4322416A (es)
JP (1) JPS5738797A (es)
AT (1) AT385510B (es)
AU (1) AU542273B2 (es)
BE (1) BE889401A (es)
CA (1) CA1173431A (es)
CH (1) CH646984A5 (es)
DE (1) DE3124780A1 (es)
DK (2) DK161151C (es)
ES (1) ES8302025A1 (es)
FR (1) FR2485543A1 (es)
GB (2) GB2078749B (es)
HK (1) HK72686A (es)
IE (1) IE51351B1 (es)
IL (1) IL63143A (es)
IT (1) IT1171339B (es)
MY (1) MY8700055A (es)
NL (1) NL8103101A (es)
NO (1) NO156693C (es)
NZ (1) NZ197494A (es)
PH (1) PH16787A (es)
SE (1) SE452325B (es)
ZA (1) ZA814220B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3362176D1 (en) * 1982-07-14 1986-03-27 Akzo Nv Novel 19-thio-androstane derivatives
DE3378208D1 (en) * 1982-12-21 1988-11-17 Ciba Geigy Ag Substituted azabicycloalkanes, their use, pharmaceutical preparations containing these compounds and process for preparing these compounds
DE3323321A1 (de) * 1983-06-24 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Prophylaxe und therapie von koronaren herzkrankheiten durch senkung des oestrogenspiegels
DE3338212C2 (de) * 1983-10-18 1995-05-18 Schering Ag 1-Methyl-androsta-1,4,6-trien-3,17-dione, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
US4634694A (en) * 1984-01-14 1987-01-06 Akzo N.V. Novel Δ4 - and Δ5 -androstene derivatives and pharmaceutical compositions containing these derivatives
US4546098A (en) * 1984-04-13 1985-10-08 The Rockefeller University Estrogen synthesis inhibitors
FR2569408B1 (fr) * 1984-08-24 1986-10-03 Roussel Uclaf Nouveaux steroides substitues en position 10 par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
GB8531747D0 (en) * 1985-12-24 1986-02-05 Erba Farmitalia 10beta-alkynylestrene derivatives
FR2594829B1 (fr) * 1986-02-24 1988-06-03 Roussel Uclaf Nouveaux steroides 9 (11) satures substitues en position 10 par un radical comportant une triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
FR2594830B1 (fr) * 1986-02-24 1988-06-03 Roussel Uclaf Nouveaux 13 epi ou d-homo steroides substitues en position 10b par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
US4874891A (en) * 1986-05-01 1989-10-17 Washington University Open "D" ring hormone analogs
US4910191A (en) * 1988-06-28 1990-03-20 Merrell Dow Pharmaceuticals Inc. 19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
US4882322A (en) * 1988-10-27 1989-11-21 Merrell Dow Pharmaceuticals Inc. 3β,17β-hydroxy-substituted steroids and related steroidal compounds
FR2640976B1 (es) * 1988-12-22 1994-10-28 Roussel Uclaf
US5162337A (en) * 1990-10-05 1992-11-10 Merck & Co., Inc. Animal growth promotion
US5166201A (en) * 1990-11-30 1992-11-24 Merrell Dow Pharmaceuticals Inc. 2β,19-ethylene bridged steroids as aromatase inhibitors
US5126488A (en) * 1990-11-30 1992-06-30 Merrell Dow Pharmaceuticals Inc. 2β,19-methyleneamino bridged steroids as aromatase inhibitors
CH683151A5 (de) * 1991-04-24 1994-01-31 Ciba Geigy Ag Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
FR2677027B1 (fr) * 1991-05-27 1993-09-10 Roussel Uclaf Nouveaux produits sterouides substitues en position 6, et comportant, en position 10, un radical thioethyle, leur procede de preparation leurs intermediaires, leur application comme medicaments.
DE4435368A1 (de) * 1994-09-22 1996-03-28 Schering Ag Verwendung von Aromatasehemmern zur Herstellung eines Arzneimittels zur Behandlung eines relativen Androgenmangels beim Mann
US5866558A (en) * 1997-05-08 1999-02-02 Regents Of The University Of Minnesota 6-alkynyl steroids
EP1854465A1 (en) * 2006-05-12 2007-11-14 Alexander Tobias Teichmann Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers
AU2011237592B2 (en) 2010-04-08 2016-10-27 Emory University Substituted androst-4-ene diones
EP3666276A1 (en) 2018-12-14 2020-06-17 dcic Biopharmaceutical Limited Medication against estrogen-receptor beta (erbeta) positive breast tumor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3127427A (en) * 1962-07-17 1964-03-31 Hoffmann La Roche 10-alkenyl-steroids and process therefor
US3218316A (en) * 1963-08-26 1965-11-16 Syntex Corp 10beta-ethynyl-19-norandrostane derivatives

Also Published As

Publication number Publication date
ATA285781A (de) 1987-09-15
IE51351B1 (en) 1986-12-10
ES503345A0 (es) 1983-01-01
IT1171339B (it) 1987-06-10
DE3124780A1 (de) 1982-06-03
SE8103963L (sv) 1981-12-28
JPS5738797A (en) 1982-03-03
NL192455C (es) 1997-08-04
GB2135314A (en) 1984-08-30
GB2078749B (en) 1983-11-16
NO156693B (no) 1987-07-27
GB2135314B (en) 1985-04-17
DK162447C (da) 1992-03-23
NO156693C (no) 1987-11-04
DE3124780C2 (es) 1992-04-23
DK161151C (da) 1991-11-18
BE889401A (fr) 1981-12-28
AT385510B (de) 1988-04-11
AU542273B2 (en) 1985-02-14
DK75190D0 (da) 1990-03-22
FR2485543B1 (es) 1983-12-23
GB2078749A (en) 1982-01-13
PH16787A (en) 1984-02-22
NZ197494A (en) 1984-11-09
DK274681A (da) 1981-12-28
IL63143A (en) 1984-10-31
ES8302025A1 (es) 1983-01-01
IE811434L (en) 1981-12-27
CA1173431A (en) 1984-08-28
NL192455B (es) 1997-04-01
IL63143A0 (en) 1981-09-13
CH646984A5 (de) 1984-12-28
DK162447B (da) 1991-10-28
AU7237081A (en) 1982-01-07
NL8103101A (nl) 1982-01-18
US4322416A (en) 1982-03-30
IT8148780A0 (it) 1981-06-26
HK72686A (en) 1986-10-03
NO812197L (no) 1981-12-28
GB8316702D0 (en) 1983-07-20
FR2485543A1 (fr) 1981-12-31
SE452325B (sv) 1987-11-23
ZA814220B (en) 1982-07-28
DK161151B (da) 1991-06-03
DK75190A (da) 1990-03-22
JPH021159B2 (es) 1990-01-10

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