MXPA05009717A - Usos de agonistas y antagonistas de interleucina-23; reactivos relacionados. - Google Patents

Usos de agonistas y antagonistas de interleucina-23; reactivos relacionados.

Info

Publication number
MXPA05009717A
MXPA05009717A MXPA05009717A MXPA05009717A MXPA05009717A MX PA05009717 A MXPA05009717 A MX PA05009717A MX PA05009717 A MXPA05009717 A MX PA05009717A MX PA05009717 A MXPA05009717 A MX PA05009717A MX PA05009717 A MXPA05009717 A MX PA05009717A
Authority
MX
Mexico
Prior art keywords
agonists
antagonists
related reagents
methods
reagents
Prior art date
Application number
MXPA05009717A
Other languages
English (en)
Inventor
Terrill K Mcclanahan
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MXPA05009717A publication Critical patent/MXPA05009717A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se proveen metodos de tratamiento de tumores; en particular, se proveen metodos para la modulacion de la actividad de una molecula de citocina y su receptor.
MXPA05009717A 2003-03-10 2004-03-09 Usos de agonistas y antagonistas de interleucina-23; reactivos relacionados. MXPA05009717A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45367203P 2003-03-10 2003-03-10
PCT/US2004/007198 WO2004081190A2 (en) 2003-03-10 2004-03-09 Uses of il-23 agonists and antagonists; related reagents

Publications (1)

Publication Number Publication Date
MXPA05009717A true MXPA05009717A (es) 2005-10-18

Family

ID=32990805

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05009717A MXPA05009717A (es) 2003-03-10 2004-03-09 Usos de agonistas y antagonistas de interleucina-23; reactivos relacionados.

Country Status (23)

Country Link
US (4) US7282204B2 (es)
EP (2) EP2108658B1 (es)
JP (4) JP4605798B2 (es)
CN (1) CN1759123B (es)
AT (1) ATE440864T1 (es)
AU (2) AU2004219625B9 (es)
BR (1) BRPI0408247A (es)
CA (1) CA2518262C (es)
CL (1) CL2004000467A1 (es)
CY (1) CY1109468T1 (es)
DE (1) DE602004022781D1 (es)
DK (1) DK1601694T3 (es)
ES (1) ES2330220T3 (es)
HK (1) HK1076477A1 (es)
MX (1) MXPA05009717A (es)
NO (1) NO20054630L (es)
NZ (2) NZ541898A (es)
PL (1) PL1601694T3 (es)
PT (1) PT1601694E (es)
SI (1) SI1601694T1 (es)
TW (2) TWI357336B (es)
WO (1) WO2004081190A2 (es)
ZA (1) ZA200506879B (es)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
KR101053412B1 (ko) * 2002-10-30 2011-08-01 제넨테크, 인크. Ｉｌ―１７ 생성의 억제
MXPA05009717A (es) * 2003-03-10 2005-10-18 Schering Corp Usos de agonistas y antagonistas de interleucina-23; reactivos relacionados.
CN101052726A (zh) * 2003-05-09 2007-10-10 森托科尔公司 IL－23p40特异性免疫球蛋白衍生蛋白、组合物、方法和用途
AU2005215527B2 (en) * 2004-02-17 2011-04-07 Merck Sharp & Dohme Corp. Methods of modulating IL-23 activity; related reagents
US20060193821A1 (en) * 2004-03-05 2006-08-31 Diener John L Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
JP2007527246A (ja) * 2004-03-05 2007-09-27 アーケミックス コーポレイション ヒトｉｌ−１２サイトカインファミリーに対するアプタマーおよび自己免疫疾患の治療剤としてのそれらの使用
AR051444A1 (es) 2004-09-24 2007-01-17 Centocor Inc Proteinas derivadas de inmunoglobulina especifica de il-23p40, composiciones, epitopos, metodos y usos
EP1853707A2 (en) 2004-12-20 2007-11-14 Schering Corporation Uses of il-23 antagonists in the treatment of diabetes mellitus
AU2006265898A1 (en) * 2005-06-30 2007-01-11 Archemix Corp. Polynucleotides and polypeptides of the IL-12 family of cytokines
WO2007005955A2 (en) * 2005-06-30 2007-01-11 Centocor, Inc. Anti-il-23 antibodies, compositions, methods and uses
AU2012258409B2 (en) * 2005-06-30 2016-01-07 Centocor, Inc. Anti-IL-23 antibodies, compositions, methods and uses
PT1937721E (pt) * 2005-08-25 2010-09-17 Lilly Co Eli Anticorpos anti-il-23
JP5350793B2 (ja) 2005-08-31 2013-11-27 メルク・シャープ・アンド・ドーム・コーポレーション 改変抗ｉｌ−２３抗体
JP2009507023A (ja) 2005-09-01 2009-02-19 シェーリング コーポレイション 自己免疫性眼炎症性疾患を処置するためのｉｌ−２３およびｉｌ−１７のアンタゴニストの使用
EA035459B1 (ru) * 2005-12-29 2020-06-19 Сентокор, Инк. Антитело против il-23p19
US7910703B2 (en) 2006-03-10 2011-03-22 Zymogenetics, Inc. Antagonists to IL-17A, IL-17F, and IL-23P19 and methods of use
EP2044118A2 (en) 2006-06-13 2009-04-08 Zymogenetics, Inc. Il-17 and il-23 antagonists and methods of using the same
EP1882699A1 (en) * 2006-07-27 2008-01-30 Heinfried Radeke Regulation of interleukin-23
TWI426918B (zh) * 2007-02-12 2014-02-21 Merck Sharp & Dohme Ｉｌ-２３拮抗劑於治療感染之用途
ATE554791T1 (de) 2007-02-23 2012-05-15 Schering Corp Gentechnisch hergestellte anti-il-23p19- antikörper
CN103396489A (zh) 2007-02-23 2013-11-20 默沙东公司 工程改造的抗IL-23p19抗体
CA2679400A1 (en) * 2007-02-28 2008-09-04 Schering Corporation Combination therapy for treatment of immune disorders
EP2057194B1 (en) 2007-02-28 2013-03-20 Merck Sharp & Dohme Corp. Engineered anti-il-23r antibodies
JP2011501941A (ja) * 2007-07-06 2011-01-20 バロリゼイション エイチエスジェイ， ソシエテ アン コマンディテ Ｉｌ−２３レセプターのアンタゴニストおよびその使用
AR068723A1 (es) * 2007-10-05 2009-12-02 Glaxo Group Ltd Proteina que se une a antigenos que se une a il-23 humana y sus usos
JPWO2009054454A1 (ja) 2007-10-24 2011-03-03 国立大学法人 東京医科歯科大学 カテプシン阻害剤を有効成分として含有するＴｏｌｌ様受容体のシグナル伝達の調整剤
NZ623706A (en) 2008-05-05 2015-12-24 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
US20110158992A1 (en) * 2008-08-27 2011-06-30 Schering Corporation Engineered Anti-IL-23R Antibodies
US20110183859A1 (en) * 2008-09-25 2011-07-28 The United States Of America, As Represented By The Secretary, Inflammatory genes and microrna-21 as biomarkers for colon cancer prognosis
PL2350316T3 (pl) * 2008-10-20 2014-10-31 Valipharma Sposoby i zastosowania obejmujące aberracje genetyczne NAV3 i nieprawidłową ekspresję wielu genów
JP2012522749A (ja) * 2009-04-01 2012-09-27 グラクソ グループ リミテッド 抗ｉｌ−２３免疫グロブリン
MX348013B (es) 2009-05-05 2017-05-23 Novimmune Sa Anticuerpos anti il-17f y metodos de uso de los mismos.
EP2456787A4 (en) * 2009-07-24 2013-01-30 Univ Leland Stanford Junior CYTOKINE COMPOSITIONS AND METHODS OF USE
US20110086806A1 (en) * 2009-10-09 2011-04-14 Anaphore, Inc. Polypeptides that Bind IL-23R
JO3244B1 (ar) 2009-10-26 2018-03-08 Amgen Inc بروتينات ربط مستضادات il – 23 البشرية
US20110311527A1 (en) 2010-06-16 2011-12-22 Allergan, Inc. IL23p19 ANTIBODY INHIBITOR FOR TREATING OCULAR AND OTHER CONDITIONS
BR112013011065B1 (pt) 2010-11-04 2022-03-15 Boehringer Ingelheim International Gmbh Anticorpo anti-il-23p19 humanizado ou seu fragmento de ligação ao antígeno, seu uso e composição farmacêutica
USRE49026E1 (en) 2011-06-14 2022-04-12 Medical Diagnostic Laboratories, Llc Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof
US8946150B2 (en) 2011-06-14 2015-02-03 Medical Diagnostic Laboratories, LLC. Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof
CA2871985C (en) 2012-05-03 2023-10-10 Boehringer Ingelheim International Gmbh Anti-il-23p19 antibodies
EP2866833B1 (en) 2012-06-27 2019-05-15 Merck Sharp & Dohme Corp. Crystalline anti-human il-23 antibodies
UA117466C2 (uk) 2012-12-13 2018-08-10 Мерк Шарп Енд Доме Корп. СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
TWI636063B (zh) 2013-03-08 2018-09-21 美國禮來大藥廠 結合ｉｌ－２３之抗體
WO2016014775A1 (en) 2014-07-24 2016-01-28 Boehringer Ingelheim International Gmbh Biomarkers useful in the treatment of il-23a related diseases
MY192824A (en) 2014-09-03 2022-09-12 Boehringer Ingelheim Int Compound targeting il-23a and tnf-alpha and uses thereof
AR102417A1 (es) 2014-11-05 2017-03-01 Lilly Co Eli Anticuerpos biespecíficos anti-tnf- / anti-il-23
CA2979210A1 (en) * 2015-03-11 2016-09-15 Rush University Medical Center Compositions and methods for treating cancer
JOP20190260A1 (ar) 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
RU2019138507A (ru) 2017-05-02 2021-06-02 Мерк Шарп И Доум Корп. Составы антител против lag3 и совместные составы антител против lag3 и антител против pd-1
AU2019383017A1 (en) 2018-11-20 2021-06-03 Janssen Biotech, Inc. Safe and effective method of treating psoriasis with anti-IL-23 specific antibody
BR112021023295A2 (pt) 2019-05-23 2022-02-08 Janssen Biotech Inc Método de tratamento de doença inflamatória intestinal com uma terapia de combinação de anticorpos para il-23 e tnf-alfa
WO2021212083A2 (en) * 2020-04-17 2021-10-21 The Board Of Trustees Of The Leland Stanford Junior University Engineered il-12 and il-23 polypeptides and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6176962B1 (en) 1990-02-28 2001-01-23 Aclara Biosciences, Inc. Methods for fabricating enclosed microchannel structures
US5783415A (en) 1991-03-29 1998-07-21 Genentech, Inc. Method of producing an IL-8 receptor polypeptide
US6132764A (en) 1994-08-05 2000-10-17 Targesome, Inc. Targeted polymerized liposome diagnostic and treatment agents
AU6501296A (en) 1995-07-21 1997-02-18 General Hospital Corporation, The Method and apparatus of enhancing the delivery of a pharmaceutical formulation
US6056973A (en) 1996-10-11 2000-05-02 Sequus Pharmaceuticals, Inc. Therapeutic liposome composition and method of preparation
US6060284A (en) * 1997-07-25 2000-05-09 Schering Corporation DNA encoding interleukin-B30
US5842787A (en) 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
US6326482B1 (en) 1999-04-23 2001-12-04 Genentech, Inc. SH2 domain-containing peptides
MXPA01005515A (es) 1998-12-01 2003-07-14 Protein Design Labs Inc Anticuerpos humanizados para gamma-interferon.
HU230679B1 (en) * 1999-09-09 2017-08-28 Merck Sharp & Dohme Mammalian interleukin-12 p40 and interleukin b30, combinations thereof, antibodies, uses in pharmaceutical compositions
CN101654479A (zh) * 2000-05-10 2010-02-24 先灵公司 哺乳动物细胞因子受体亚单位蛋白、相关试剂及方法
JP2005507632A (ja) * 2000-10-06 2005-03-24 イミュネックス・コーポレーション ヘマトポエチン受容体、ｈｐｒ１およびｈｐｒ２
AU2002314825A1 (en) * 2001-05-30 2002-12-09 Centocor, Inc. Anti-p40 immunoglobulin derived proteins, compositions, methods and uses
MXPA05009717A (es) * 2003-03-10 2005-10-18 Schering Corp Usos de agonistas y antagonistas de interleucina-23; reactivos relacionados.

Also Published As

Publication number Publication date
ATE440864T1 (de) 2009-09-15
SI1601694T1 (sl) 2010-01-29
EP1601694B1 (en) 2009-08-26
EP2108658A1 (en) 2009-10-14
US20080057058A1 (en) 2008-03-06
AU2010212372B2 (en) 2012-12-20
TW201141521A (en) 2011-12-01
NZ567860A (en) 2009-11-27
JP4605798B2 (ja) 2011-01-05
US20040223969A1 (en) 2004-11-11
AU2010212372A1 (en) 2010-09-09
TWI357336B (en) 2012-02-01
WO2004081190A3 (en) 2005-02-03
US8034341B2 (en) 2011-10-11
BRPI0408247A (pt) 2006-03-01
EP2108658B1 (en) 2016-06-08
CN1759123A (zh) 2006-04-12
NZ541898A (en) 2008-07-31
CN1759123B (zh) 2011-04-13
TW200505479A (en) 2005-02-16
PL1601694T3 (pl) 2010-02-26
PT1601694E (pt) 2009-12-03
CA2518262A1 (en) 2004-09-23
JP2011032275A (ja) 2011-02-17
AU2004219625B2 (en) 2010-08-19
ES2330220T3 (es) 2009-12-07
AU2004219625B9 (en) 2010-12-23
NO20054630D0 (no) 2005-10-07
TWI439285B (zh) 2014-06-01
DK1601694T3 (da) 2009-12-14
WO2004081190A2 (en) 2004-09-23
JP2006520781A (ja) 2006-09-14
JP2014005286A (ja) 2014-01-16
HK1076477A1 (en) 2006-01-20
CL2004000467A1 (es) 2005-05-06
CA2518262C (en) 2014-05-06
NO20054630L (no) 2005-10-07
AU2004219625A1 (en) 2004-09-23
EP1601694A2 (en) 2005-12-07
ZA200506879B (en) 2006-05-31
JP2007197453A (ja) 2007-08-09
DE602004022781D1 (de) 2009-10-08
CY1109468T1 (el) 2014-08-13
US7282204B2 (en) 2007-10-16
US20100003251A1 (en) 2010-01-07
US20120034219A1 (en) 2012-02-09

Similar Documents

Publication Publication Date Title
TW200505479A (en) Uses of IL-23 agonists and antagonists; related reagents
ZA200606620B (en) Methods of modulating IL-23 activity ; related reagents
TWI372628B (en) Methods of modulating cytokine activity; related reagents
TW200531679A (en) Methods of modulating cytokine activity; related reagents
CY1108645T1 (el) Θεραπεια και διαγνωση νεοπλασματων χρησιμοποιωντας θυμικη στρωματικη λεμφοποιητινη
TW200644685A (en) Techniques to manage roaming
ZA200701656B (en) Humanized anti-cment antagonists
NO20053590D0 (no) Dobbel modusenhet for kortdistanse, hoyrate og langstanse, lavere dataratekommunikasjon.
TW200604843A (en) Location processing apparatus, systems, and methods
WO2006052409A3 (en) Peptide and small molecule agonists of epha and their uses
HK1074670A1 (en) Sets of digital antibodies directed against short epitopes, and methods using same
WO2004058191A3 (en) Multivalent lymphotoxin beta receptor agonists and therapeutic uses thereof
WO2003104425A3 (en) NEW STABLE ANTI-CD22 ANTIBODIES
EP1589998A4 (en) USES OF MAMMALIAN CYTOKINE AND RELATED REAGENTS
MY133625A (en) Peptide deformylase inhibitors
WO2006104761A3 (en) Unique sequence hybridization probes (usp)
GB2399991B (en) Mobile communication methods, systems and apparatus for use therein
MXPA05012297A (es) Indazol que tiene actividad analgesica.
AU2003304490A1 (en) Peptide deformylase inhibitors
AU2002258437A1 (en) Peptide deformylase inhibitors
WO2005005456A3 (en) Peptide deformylase inhibitors
IL163899A0 (en) Peptide deformylase inhibitors
WO2005060998A3 (en) Methods of modulating cytokine activity; related reagents
AU2002322035A1 (en) Peptide deformylase inhibitors
AU2002255635A1 (en) Peptide deformylase inhibitors

Legal Events

Date Code Title Description
FG Grant or registration
HC Change of company name or juridical status