MXPA04004974A - Composiciones farmaceuticas que comprenden metformina y glibenclamida para tratamiento de diabetes mellitus tipo ii. - Google Patents
Composiciones farmaceuticas que comprenden metformina y glibenclamida para tratamiento de diabetes mellitus tipo ii.Info
- Publication number
- MXPA04004974A MXPA04004974A MXPA04004974A MXPA04004974A MXPA04004974A MX PA04004974 A MXPA04004974 A MX PA04004974A MX PA04004974 A MXPA04004974 A MX PA04004974A MX PA04004974 A MXPA04004974 A MX PA04004974A MX PA04004974 A MXPA04004974 A MX PA04004974A
- Authority
- MX
- Mexico
- Prior art keywords
- glibenclamide
- treatment
- type
- pharmaceutical compositions
- diabetes mellitus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Se describen composiciones farmaceuticas que son suministrables por la via oral en forma de comprimidos para el tratamiento de la diabetes mellitus tipo II, que comprenden glibenclamida y metformina, o sus sales farmaceuticamente aceptables, como ingredientes activos, mantenidos en forma separada entre si dentro de la misma composicion.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2001FI000230A ITFI20010230A1 (it) | 2001-11-29 | 2001-11-29 | Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii |
PCT/EP2002/013497 WO2003045355A1 (en) | 2001-11-29 | 2002-11-29 | Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-ii diabetes mellitus |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA04004974A true MXPA04004974A (es) | 2004-08-11 |
Family
ID=11442301
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA04004974A MXPA04004974A (es) | 2001-11-29 | 2002-11-29 | Composiciones farmaceuticas que comprenden metformina y glibenclamida para tratamiento de diabetes mellitus tipo ii. |
Country Status (40)
Country | Link |
---|---|
US (1) | US20050053661A1 (es) |
EP (1) | EP1458364B1 (es) |
JP (1) | JP4474162B2 (es) |
KR (1) | KR20040079898A (es) |
CN (1) | CN1596103B (es) |
AR (1) | AR037407A1 (es) |
AT (1) | ATE387190T1 (es) |
AU (1) | AU2002358061B2 (es) |
BR (1) | BR0214403A (es) |
CA (1) | CA2466677A1 (es) |
CO (1) | CO5590906A2 (es) |
CY (1) | CY1107966T1 (es) |
DE (1) | DE60225331T2 (es) |
DK (1) | DK1458364T3 (es) |
EA (1) | EA006766B1 (es) |
EG (1) | EG24124A (es) |
ES (1) | ES2302862T3 (es) |
HK (1) | HK1069974A1 (es) |
HN (1) | HN2002000341A (es) |
HR (1) | HRP20040501A2 (es) |
HU (1) | HUP0402154A3 (es) |
IL (1) | IL162143A0 (es) |
IT (1) | ITFI20010230A1 (es) |
MA (1) | MA27087A1 (es) |
MX (1) | MXPA04004974A (es) |
MY (1) | MY141243A (es) |
NO (1) | NO20042713L (es) |
NZ (1) | NZ533779A (es) |
PA (1) | PA8559801A1 (es) |
PE (1) | PE20030580A1 (es) |
PL (1) | PL206016B1 (es) |
PT (1) | PT1458364E (es) |
RS (1) | RS50937B (es) |
SI (1) | SI1458364T1 (es) |
SV (1) | SV2004001415A (es) |
TN (1) | TNSN04095A1 (es) |
UA (1) | UA81615C2 (es) |
UY (1) | UY27549A1 (es) |
WO (1) | WO2003045355A1 (es) |
ZA (1) | ZA200404880B (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL362687A1 (en) * | 2001-01-12 | 2004-11-02 | Sun Pharmaceutical Industries Limited | Spaced drug delivery system |
US8911781B2 (en) | 2002-06-17 | 2014-12-16 | Inventia Healthcare Private Limited | Process of manufacture of novel drug delivery system: multilayer tablet composition of thiazolidinedione and biguanides |
US9060941B2 (en) | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US7785627B2 (en) | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
DK2316456T3 (en) | 2003-04-29 | 2017-09-11 | Orexigen Therapeutics Inc | Compositions for affecting weight loss comprising an opioid antagonist and bupropion |
UY29445A1 (es) * | 2005-03-30 | 2006-10-02 | Generex Pharm Inc | Composiciones para la transmisión transmucosa oral de la metformina |
TWI471145B (zh) * | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
KR101735466B1 (ko) * | 2006-11-09 | 2017-05-15 | 오렉시젠 세러퓨틱스 인크. | 신속하게 용해되는 중간층을 포함하는 층상의 약제학적 제형 |
ITMI20062254A1 (it) * | 2006-11-24 | 2008-05-25 | Acraf | Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca |
JP2011521973A (ja) | 2008-05-30 | 2011-07-28 | オレキシジェン・セラピューティクス・インコーポレーテッド | 内臓脂肪の状態を処置するための方法 |
CA2638240C (en) | 2008-08-29 | 2010-02-02 | Alexander Macgregor | Method of treating dysglycemia and glucose excursions |
CN102724878A (zh) | 2010-01-11 | 2012-10-10 | 奥雷西根治疗公司 | 在重度抑郁症患者中提供体重减轻疗法的方法 |
RU2483717C2 (ru) * | 2010-11-22 | 2013-06-10 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Фармацевтическая композиция для лечения диабета (варианты) |
US11974971B2 (en) | 2011-01-07 | 2024-05-07 | Anji Pharmaceuticals Inc. | Compositions and methods for treating metabolic disorders |
US11759441B2 (en) | 2011-01-07 | 2023-09-19 | Anji Pharmaceuticals Inc. | Biguanide compositions and methods of treating metabolic disorders |
US9572784B2 (en) | 2011-01-07 | 2017-02-21 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
WO2013103919A2 (en) | 2012-01-06 | 2013-07-11 | Elcelyx Therapeutics, Inc. | Compositions and methods for treating metabolic disorders |
US8796338B2 (en) | 2011-01-07 | 2014-08-05 | Elcelyx Therapeutics, Inc | Biguanide compositions and methods of treating metabolic disorders |
KR20140035331A (ko) | 2011-01-07 | 2014-03-21 | 엘셀릭스 테라퓨틱스 인코포레이티드 | 화학감각 수용체 리간드-기반 요법 |
US9211263B2 (en) | 2012-01-06 | 2015-12-15 | Elcelyx Therapeutics, Inc. | Compositions and methods of treating metabolic disorders |
US9480663B2 (en) | 2011-01-07 | 2016-11-01 | Elcelyx Therapeutics, Inc. | Biguanide compositions and methods of treating metabolic disorders |
KR102035879B1 (ko) | 2012-01-06 | 2019-10-23 | 엘셀릭스 테라퓨틱스 인코포레이티드 | 바이구아나이드 조성물 및 대사 장애를 치료하는 방법 |
LT3730132T (lt) | 2012-06-06 | 2022-08-25 | Nalpropion Pharmaceuticals Llc | Kompozicija, skirta panaudoti pacientų su didele širdies ir kraujagyslių ligų rizika antsvorio ir nutukimo gydymo būde |
WO2016076280A1 (ja) | 2014-11-11 | 2016-05-19 | 塩野義製薬株式会社 | 光に対して不安定な薬物を含有する多層錠剤 |
KR101750690B1 (ko) * | 2015-10-28 | 2017-06-27 | 주식회사 종근당 | 메트포르민 및 로베글리타존을 포함하는 약제학적 조성물 |
CN105596339A (zh) * | 2015-12-23 | 2016-05-25 | 青岛海之源智能技术有限公司 | 一种二甲双胍阿昔莫司复方组合物及制备方法 |
CN110128305A (zh) * | 2019-05-10 | 2019-08-16 | 天津大学 | 二甲双胍-甲苯磺丁脲新盐型、其制备方法及医药用途 |
JP2021120357A (ja) * | 2020-01-30 | 2021-08-19 | サンノーバ株式会社 | 錠剤 |
GB2599950A (en) * | 2020-10-16 | 2022-04-20 | Zentiva Ks | Pharmaceutical compositions with low amounts of nitrosamine impurities and methods for producing the same |
CN113143940A (zh) * | 2020-12-30 | 2021-07-23 | 成都恒瑞制药有限公司 | 一种抗糖尿病药物组合物的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2347531A1 (de) * | 1973-09-21 | 1975-04-30 | Hoechst Ag | Arzneizubereitungen zur oralen diabetes-behandlung |
IT1276130B1 (it) * | 1995-11-14 | 1997-10-27 | Gentili Ist Spa | Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo |
NZ506202A (en) * | 1998-03-19 | 2003-10-31 | Bristol Myers Squibb Co | Biphasic controlled release delivery system for high solubility pharmaceuticals and method |
DK0974356T3 (da) * | 1998-07-15 | 2003-10-27 | Merck Sante Sas | Tabletter omfattende en kombination af metformin og glibenclamid |
US6780432B1 (en) * | 2000-05-01 | 2004-08-24 | Aeropharm Technology, Inc. | Core formulation |
PL362687A1 (en) * | 2001-01-12 | 2004-11-02 | Sun Pharmaceutical Industries Limited | Spaced drug delivery system |
-
2001
- 2001-11-29 IT IT2001FI000230A patent/ITFI20010230A1/it unknown
-
2002
- 2002-11-22 AR ARP020104498A patent/AR037407A1/es unknown
- 2002-11-25 MY MYPI20024393A patent/MY141243A/en unknown
- 2002-11-26 PE PE2002001140A patent/PE20030580A1/es not_active Application Discontinuation
- 2002-11-26 UY UY27549A patent/UY27549A1/es not_active Application Discontinuation
- 2002-11-27 EG EG2002111281A patent/EG24124A/xx active
- 2002-11-28 SV SV2002001415A patent/SV2004001415A/es not_active Application Discontinuation
- 2002-11-29 EA EA200400664A patent/EA006766B1/ru not_active IP Right Cessation
- 2002-11-29 DK DK02791739T patent/DK1458364T3/da active
- 2002-11-29 MX MXPA04004974A patent/MXPA04004974A/es active IP Right Grant
- 2002-11-29 DE DE60225331T patent/DE60225331T2/de not_active Expired - Lifetime
- 2002-11-29 SI SI200230693T patent/SI1458364T1/sl unknown
- 2002-11-29 UA UA20040504085A patent/UA81615C2/ru unknown
- 2002-11-29 HN HN2002000341A patent/HN2002000341A/es unknown
- 2002-11-29 CN CN028236920A patent/CN1596103B/zh not_active Expired - Fee Related
- 2002-11-29 WO PCT/EP2002/013497 patent/WO2003045355A1/en active IP Right Grant
- 2002-11-29 KR KR10-2004-7006874A patent/KR20040079898A/ko not_active Application Discontinuation
- 2002-11-29 PL PL369851A patent/PL206016B1/pl not_active IP Right Cessation
- 2002-11-29 BR BR0214403-4A patent/BR0214403A/pt not_active IP Right Cessation
- 2002-11-29 AU AU2002358061A patent/AU2002358061B2/en not_active Ceased
- 2002-11-29 PA PA20028559801A patent/PA8559801A1/es unknown
- 2002-11-29 PT PT02791739T patent/PT1458364E/pt unknown
- 2002-11-29 CA CA002466677A patent/CA2466677A1/en not_active Abandoned
- 2002-11-29 HU HU0402154A patent/HUP0402154A3/hu unknown
- 2002-11-29 JP JP2003546858A patent/JP4474162B2/ja not_active Expired - Lifetime
- 2002-11-29 NZ NZ533779A patent/NZ533779A/en not_active IP Right Cessation
- 2002-11-29 AT AT02791739T patent/ATE387190T1/de not_active IP Right Cessation
- 2002-11-29 IL IL16214302A patent/IL162143A0/xx not_active IP Right Cessation
- 2002-11-29 US US10/497,022 patent/US20050053661A1/en not_active Abandoned
- 2002-11-29 EP EP02791739A patent/EP1458364B1/en not_active Expired - Lifetime
- 2002-11-29 ES ES02791739T patent/ES2302862T3/es not_active Expired - Lifetime
-
2004
- 2004-05-24 MA MA27696A patent/MA27087A1/fr unknown
- 2004-05-28 TN TNP2004000095A patent/TNSN04095A1/en unknown
- 2004-05-28 RS YUP-473/04A patent/RS50937B/sr unknown
- 2004-06-04 HR HRP20040501 patent/HRP20040501A2/hr not_active Application Discontinuation
- 2004-06-21 ZA ZA200404880A patent/ZA200404880B/en unknown
- 2004-06-28 NO NO20042713A patent/NO20042713L/no not_active Application Discontinuation
- 2004-06-29 CO CO04061363A patent/CO5590906A2/es not_active Application Discontinuation
-
2005
- 2005-03-18 HK HK05102373A patent/HK1069974A1/xx not_active IP Right Cessation
-
2008
- 2008-05-26 CY CY20081100543T patent/CY1107966T1/el unknown
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Legal Events
Date | Code | Title | Description |
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FG | Grant or registration |