CY1107966T1 - Φαρμακευτικες συνθεσεις οι οποιες περιλαμβανουν μετφορμινη και γλιβενκλαμιδη για τη θεραπεια του σακχαρωδους διαβητη τυπου ii - Google Patents

Φαρμακευτικες συνθεσεις οι οποιες περιλαμβανουν μετφορμινη και γλιβενκλαμιδη για τη θεραπεια του σακχαρωδους διαβητη τυπου ii

Info

Publication number
CY1107966T1
CY1107966T1 CY20081100543T CY081100543T CY1107966T1 CY 1107966 T1 CY1107966 T1 CY 1107966T1 CY 20081100543 T CY20081100543 T CY 20081100543T CY 081100543 T CY081100543 T CY 081100543T CY 1107966 T1 CY1107966 T1 CY 1107966T1
Authority
CY
Cyprus
Prior art keywords
glibenclamide
treatment
type
diabetes
metformine
Prior art date
Application number
CY20081100543T
Other languages
English (en)
Inventor
Alessandro Tosetti
Mauro Guiducci
Giovanni Viti
Original Assignee
Menarini International Operations
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11442301&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1107966(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Menarini International Operations filed Critical Menarini International Operations
Publication of CY1107966T1 publication Critical patent/CY1107966T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Στην παρούσα εφεύρεση περιγράφονται φαρμακευτικές συνθέσεις υπό την μορφή δισκίων, χορηγούμενες δια της στοματικής οδού, οι οποίες περιλαμβάνουν γλιβενκλαμίδη και μετφορμίνη ή φαρμακευτικώς αποδεκτά άλατα αυτών, ως δραστικές ουσίες, και διατηρούνται ξεχωριστά η μια από την άλλη μέσα στην ίδια σύνθεση, για την θεραπεία του σακχαρώδη διαβήτη τύπου II.
CY20081100543T 2001-11-29 2008-05-26 Φαρμακευτικες συνθεσεις οι οποιες περιλαμβανουν μετφορμινη και γλιβενκλαμιδη για τη θεραπεια του σακχαρωδους διαβητη τυπου ii CY1107966T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2001FI000230A ITFI20010230A1 (it) 2001-11-29 2001-11-29 Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
EP02791739A EP1458364B1 (en) 2001-11-29 2002-11-29 Pharmaceutical compositions comprising metformine and glibenclamide for the treatment of type-ii diabetes mellitus

Publications (1)

Publication Number Publication Date
CY1107966T1 true CY1107966T1 (el) 2013-09-04

Family

ID=11442301

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100543T CY1107966T1 (el) 2001-11-29 2008-05-26 Φαρμακευτικες συνθεσεις οι οποιες περιλαμβανουν μετφορμινη και γλιβενκλαμιδη για τη θεραπεια του σακχαρωδους διαβητη τυπου ii

Country Status (40)

Country Link
US (1) US20050053661A1 (el)
EP (1) EP1458364B1 (el)
JP (1) JP4474162B2 (el)
KR (1) KR20040079898A (el)
CN (1) CN1596103B (el)
AR (1) AR037407A1 (el)
AT (1) ATE387190T1 (el)
AU (1) AU2002358061B2 (el)
BR (1) BR0214403A (el)
CA (1) CA2466677A1 (el)
CO (1) CO5590906A2 (el)
CY (1) CY1107966T1 (el)
DE (1) DE60225331T2 (el)
DK (1) DK1458364T3 (el)
EA (1) EA006766B1 (el)
EG (1) EG24124A (el)
ES (1) ES2302862T3 (el)
HK (1) HK1069974A1 (el)
HN (1) HN2002000341A (el)
HR (1) HRP20040501A2 (el)
HU (1) HUP0402154A3 (el)
IL (1) IL162143A0 (el)
IT (1) ITFI20010230A1 (el)
MA (1) MA27087A1 (el)
MX (1) MXPA04004974A (el)
MY (1) MY141243A (el)
NO (1) NO20042713L (el)
NZ (1) NZ533779A (el)
PA (1) PA8559801A1 (el)
PE (1) PE20030580A1 (el)
PL (1) PL206016B1 (el)
PT (1) PT1458364E (el)
RS (1) RS50937B (el)
SI (1) SI1458364T1 (el)
SV (1) SV2004001415A (el)
TN (1) TNSN04095A1 (el)
UA (1) UA81615C2 (el)
UY (1) UY27549A1 (el)
WO (1) WO2003045355A1 (el)
ZA (1) ZA200404880B (el)

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EP1738751B1 (en) * 2001-01-12 2011-05-11 Sun Pharma Advanced Research Company Ltd Spaced drug delivery system
EP1515701B1 (en) 2002-06-17 2014-09-17 Inventia Healthcare Private Limited Process for the manufacture of multilayer tablet compositions comprising thiazolidinedione and biguanide
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
JP4343948B2 (ja) 2003-04-29 2009-10-14 オレキシジェン・セラピューティクス・インコーポレーテッド 体重減少に影響を及ぼすための組成物
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
TWI471145B (zh) * 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
DK2089005T3 (da) * 2006-11-09 2010-07-19 Orexigen Therapeutics Inc Lagdelte farmaceutiske formuleringer omfattende et hurtigt opløsende mellemlag
ITMI20062254A1 (it) * 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
CA2725930A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
CA2638240C (en) 2008-08-29 2010-02-02 Alexander Macgregor Method of treating dysglycemia and glucose excursions
CN102724878A (zh) 2010-01-11 2012-10-10 奥雷西根治疗公司 在重度抑郁症患者中提供体重减轻疗法的方法
RU2483717C2 (ru) * 2010-11-22 2013-06-10 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтическая композиция для лечения диабета (варианты)
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US9480663B2 (en) 2011-01-07 2016-11-01 Elcelyx Therapeutics, Inc. Biguanide compositions and methods of treating metabolic disorders
CA2823397C (en) 2011-01-07 2020-03-10 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
US9211263B2 (en) 2012-01-06 2015-12-15 Elcelyx Therapeutics, Inc. Compositions and methods of treating metabolic disorders
US9572784B2 (en) 2011-01-07 2017-02-21 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
US8796338B2 (en) 2011-01-07 2014-08-05 Elcelyx Therapeutics, Inc Biguanide compositions and methods of treating metabolic disorders
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
ES2832773T3 (es) 2012-01-06 2021-06-11 Anji Pharma Us Llc Composiciones de biguanida y métodos de tratamiento de trastornos metabólicos
MX2014008189A (es) 2012-01-06 2015-02-12 Elcelyx Therapeutics Inc Composiciones y metodos para tratar trastornos metabolicos.
EA201492175A1 (ru) 2012-06-06 2015-10-30 Орексиджен Терапьютикс, Инк. Способы лечения избыточного веса и ожирения
KR20170083071A (ko) 2014-11-11 2017-07-17 시오노기 앤드 컴파니, 리미티드 광에 대해서 불안정한 약물을 함유하는 다층 정제
KR101750690B1 (ko) * 2015-10-28 2017-06-27 주식회사 종근당 메트포르민 및 로베글리타존을 포함하는 약제학적 조성물
CN105596339A (zh) * 2015-12-23 2016-05-25 青岛海之源智能技术有限公司 一种二甲双胍阿昔莫司复方组合物及制备方法
CN110128305A (zh) * 2019-05-10 2019-08-16 天津大学 二甲双胍-甲苯磺丁脲新盐型、其制备方法及医药用途
JP2021120357A (ja) * 2020-01-30 2021-08-19 サンノーバ株式会社 錠剤
GB2599950A (en) * 2020-10-16 2022-04-20 Zentiva Ks Pharmaceutical compositions with low amounts of nitrosamine impurities and methods for producing the same
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

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DE2347531A1 (de) * 1973-09-21 1975-04-30 Hoechst Ag Arzneizubereitungen zur oralen diabetes-behandlung
IT1276130B1 (it) * 1995-11-14 1997-10-27 Gentili Ist Spa Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
CN1203846C (zh) * 1998-03-19 2005-06-01 布里斯托尔-迈尔斯斯奎布公司 高溶解性药物的双相控释递送***和方法
DK0974356T3 (da) * 1998-07-15 2003-10-27 Merck Sante Sas Tabletter omfattende en kombination af metformin og glibenclamid
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EP1738751B1 (en) * 2001-01-12 2011-05-11 Sun Pharma Advanced Research Company Ltd Spaced drug delivery system

Also Published As

Publication number Publication date
MY141243A (en) 2010-03-31
AU2002358061A1 (en) 2003-06-10
PL369851A1 (en) 2005-05-02
UA81615C2 (ru) 2008-01-25
EA006766B1 (ru) 2006-04-28
IL162143A0 (en) 2005-11-20
HK1069974A1 (en) 2005-06-10
HN2002000341A (es) 2009-12-07
JP2005518360A (ja) 2005-06-23
EP1458364B1 (en) 2008-02-27
WO2003045355A1 (en) 2003-06-05
PT1458364E (pt) 2008-05-26
AR037407A1 (es) 2004-11-10
CO5590906A2 (es) 2005-12-30
JP4474162B2 (ja) 2010-06-02
MXPA04004974A (es) 2004-08-11
EP1458364A1 (en) 2004-09-22
PL206016B1 (pl) 2010-06-30
US20050053661A1 (en) 2005-03-10
PE20030580A1 (es) 2003-09-05
RS47304A (en) 2006-10-27
UY27549A1 (es) 2003-06-30
KR20040079898A (ko) 2004-09-16
NO20042713L (no) 2004-07-16
MA27087A1 (fr) 2004-12-20
CA2466677A1 (en) 2003-06-05
DE60225331D1 (de) 2008-04-10
SI1458364T1 (sl) 2008-08-31
DE60225331T2 (de) 2009-02-26
TNSN04095A1 (en) 2006-06-01
ATE387190T1 (de) 2008-03-15
EA200400664A1 (ru) 2004-10-28
CN1596103A (zh) 2005-03-16
EG24124A (en) 2008-07-07
ITFI20010230A1 (it) 2003-05-29
PA8559801A1 (es) 2003-06-30
HUP0402154A2 (hu) 2005-02-28
HRP20040501A2 (en) 2004-12-31
BR0214403A (pt) 2004-10-19
SV2004001415A (es) 2004-05-07
ZA200404880B (en) 2005-07-29
RS50937B (sr) 2010-08-31
NZ533779A (en) 2007-02-23
CN1596103B (zh) 2010-06-16
AU2002358061B2 (en) 2007-01-11
DK1458364T3 (da) 2008-06-23
ES2302862T3 (es) 2008-08-01
HUP0402154A3 (en) 2008-04-28

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