MX9706841A - Variantes de proteinasa k que tienen adsorcion reducida e hidrolisis incrementada. - Google Patents

Variantes de proteinasa k que tienen adsorcion reducida e hidrolisis incrementada.

Info

Publication number
MX9706841A
MX9706841A MX9706841A MX9706841A MX9706841A MX 9706841 A MX9706841 A MX 9706841A MX 9706841 A MX9706841 A MX 9706841A MX 9706841 A MX9706841 A MX 9706841A MX 9706841 A MX9706841 A MX 9706841A
Authority
MX
Mexico
Prior art keywords
proteinase
variants
loop region
wild
acid sequence
Prior art date
Application number
MX9706841A
Other languages
English (en)
Inventor
Philip Frederick Brode Iii
Bobby Lee Barnett
Donn Nelton Rubingh
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MX9706841A publication Critical patent/MX9706841A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0047—Detergents in the form of bars or tablets
    • C11D17/0065—Solid detergents containing builders
    • C11D17/0073—Tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0047—Detergents in the form of bars or tablets
    • C11D17/0065—Solid detergents containing builders
    • C11D17/0069—Laundry bars
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0047—Detergents in the form of bars or tablets
    • C11D17/0065—Solid detergents containing builders
    • C11D17/0073—Tablets
    • C11D17/0078—Multilayered tablets
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0052—Gas evolving or heat producing compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invencion se refiere a variantes de proteinasa K que tienen una secuencia de amioácido modificada de secuencia de aminoácidos de proteinasa K de tipo silvestre, la secuencia de aminoácidos de tipo silvestre comprendiendo una primera region de lazo, una segunda region de lazo, una tercera region de lazo, una cuarta region de lazo; en la que la secuencia de aminoácidos comprende diferentes aminoácidos a los que ocurren en la proteinasa K de tipo silvestre (es decir, sustitucion) en posiciones identificadas específicas en una o más de las regiones de lazo, por medio de las cuales la variante de proteinasa K tiene adsorcion reducida con la proteinasa K de tipo silvestre; la presente invencion se refiere también a secuencias de ADN que codifican tales variantes de proteinasa K para una variante de superficies.
MX9706841A 1995-03-09 1996-03-06 Variantes de proteinasa k que tienen adsorcion reducida e hidrolisis incrementada. MX9706841A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40157495A 1995-03-09 1995-03-09
PCT/US1996/003005 WO1996028556A2 (en) 1995-03-09 1996-03-06 Proteinase k variants having decreased adsorption and increased hydrolysis

Publications (1)

Publication Number Publication Date
MX9706841A true MX9706841A (es) 1997-11-29

Family

ID=23588288

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9706841A MX9706841A (es) 1995-03-09 1996-03-06 Variantes de proteinasa k que tienen adsorcion reducida e hidrolisis incrementada.

Country Status (14)

Country Link
US (1) US6451574B1 (es)
EP (1) EP0813601A2 (es)
JP (1) JPH11501814A (es)
CN (1) CN1183809A (es)
AU (1) AU5092796A (es)
BR (1) BR9607677A (es)
CA (1) CA2214395C (es)
CZ (1) CZ279997A3 (es)
HU (1) HUP9801638A3 (es)
IL (1) IL117350A0 (es)
MA (1) MA23820A1 (es)
MX (1) MX9706841A (es)
WO (1) WO1996028556A2 (es)
ZA (1) ZA961820B (es)

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CN109280656B (zh) * 2018-10-23 2021-06-15 大连博格林生物科技有限公司 重组布氏白僵菌蛋白酶k突变体pk-m1及制备方法
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CN112592931A (zh) * 2020-12-31 2021-04-02 安徽丰原发酵技术工程研究有限公司 一种生产重组蛋白酶k的方法
CN113913412B (zh) * 2021-10-13 2023-10-03 湖北大学 蛋白酶k突变体及其制备方法
CN114196656B (zh) * 2021-12-29 2023-10-24 南京巨匠生物科技有限公司 一种蛋白酶k突变体及其表达载体的构建和应用
CN115775591B (zh) * 2023-01-10 2023-06-09 华测检测认证集团股份有限公司 一种引物设计方法、装置、设备及可读存储介质

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Also Published As

Publication number Publication date
HUP9801638A2 (hu) 1998-10-28
IL117350A0 (en) 1996-07-23
WO1996028556A3 (en) 1997-07-17
MA23820A1 (fr) 1996-10-01
HUP9801638A3 (en) 2001-01-29
ZA961820B (en) 1996-09-10
CZ279997A3 (cs) 1998-01-14
AU5092796A (en) 1996-10-02
EP0813601A2 (en) 1997-12-29
BR9607677A (pt) 1998-07-07
US6451574B1 (en) 2002-09-17
WO1996028556A2 (en) 1996-09-19
CA2214395C (en) 2001-10-30
CA2214395A1 (en) 1996-09-19
CN1183809A (zh) 1998-06-03
JPH11501814A (ja) 1999-02-16

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TH41969A (th) โปรทิเอสดัดแปลงชนิดแทนที่หลายตำแหน่งซึ่งมีประจุสุทธิเปลี่ยนแปลงสำหรับการใช้ประโยชน์ในสารซักฟอก