MX9305467A - Compuestos intermedios, quirales, de quinolona y procedimiento para su preparacion. - Google Patents

Compuestos intermedios, quirales, de quinolona y procedimiento para su preparacion.

Info

Publication number
MX9305467A
MX9305467A MX9305467A MX9305467A MX9305467A MX 9305467 A MX9305467 A MX 9305467A MX 9305467 A MX9305467 A MX 9305467A MX 9305467 A MX9305467 A MX 9305467A MX 9305467 A MX9305467 A MX 9305467A
Authority
MX
Mexico
Prior art keywords
quiral
procedure
preparation
quinolone compounds
quinolone
Prior art date
Application number
MX9305467A
Other languages
English (en)
Inventor
Daniel T Chu
Qun Li
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX9305467A publication Critical patent/MX9305467A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C07C255/25—Aminoacetonitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

En la presente invención se describen compuestos quirales que tienen las fórmulas: (Ver fórmula); útiles en la síntesis de compuestos intermedios de quinolona.
MX9305467A 1992-09-11 1993-09-07 Compuestos intermedios, quirales, de quinolona y procedimiento para su preparacion. MX9305467A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/943,946 US5252747A (en) 1992-09-11 1992-09-11 Chiral quinolone intermediates

Publications (1)

Publication Number Publication Date
MX9305467A true MX9305467A (es) 1994-08-31

Family

ID=25480529

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9305467A MX9305467A (es) 1992-09-11 1993-09-07 Compuestos intermedios, quirales, de quinolona y procedimiento para su preparacion.

Country Status (6)

Country Link
US (1) US5252747A (es)
EP (1) EP0659178A4 (es)
JP (1) JPH08501306A (es)
CA (1) CA2135889A1 (es)
MX (1) MX9305467A (es)
WO (1) WO1994006766A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI220143B (en) * 1998-05-13 2004-08-11 Solvay Pharm Gmbh Method for stereochemically controlled production of isomerically pure highly substituted azacyclic compounds and novel cyclic compounds, and intermediate products
KR20030020646A (ko) * 2001-09-04 2003-03-10 한미약품공업 주식회사 2-(에스)-아미노-4-페닐부틸산의 개선된 제조방법
US8278313B2 (en) * 2008-03-11 2012-10-02 Abbott Laboratories Macrocyclic spiro pyrimidine derivatives
US8436005B2 (en) * 2008-04-03 2013-05-07 Abbott Laboratories Macrocyclic pyrimidine derivatives
EP2578732B1 (de) 2011-10-05 2014-04-30 Groz-Beckert KG Webschaft mit einem Leichtbau-Schaftstab

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210660A (en) * 1978-12-20 1980-07-01 Yamanouchi Pharmaceutical Co., Ltd. Benzamide derivatives
DE2855853C2 (de) * 1978-12-22 1986-09-11 Yamanouchi Pharmaceutical Co., Ltd., Tokio/Tokyo N-(1-Benzyl-2-methyl-3-pyrrolidinyl)-5-chlor-2-methoxy-4-methylaminobenzamid dessen Säureadditionssalze, Verfahren zu deren Herstellung und ihre Verwendung
JPS57197264A (en) * 1981-05-29 1982-12-03 Res Dev Corp Of Japan (2s,4s)-2-(anilinomethyl)-1-ethyl-4-hydroxypyrrolidine and its synthesis
JPS62246595A (ja) * 1986-04-17 1987-10-27 Eisai Co Ltd 気菅支拡張作用・降圧作用ペプタイド
JPS62246551A (ja) * 1987-02-04 1987-10-27 Teikoku Hormone Mfg Co Ltd 新規な置換フエノキシプロピルアミン誘導体
US5144072A (en) * 1988-10-21 1992-09-01 American Home Products Corporation Anti-arrhythmic agents
JP2739506B2 (ja) * 1989-09-28 1998-04-15 ダイソー株式会社 新規ヒドロキシピロリジン化合物、その製造用中間体およびそれらの製造方法
JPH0776209B2 (ja) * 1990-04-11 1995-08-16 高砂香料工業株式会社 光学活性３―ヒドロキシピロリジン誘導体の製造方法
IE911472A1 (en) * 1990-05-02 1991-11-06 Abbott Lab Quinolizinone type compounds
JP3086837B2 (ja) * 1991-06-06 2000-09-11 三協化学株式会社 ３−アミノピロリジン類の製造方法

Also Published As

Publication number Publication date
JPH08501306A (ja) 1996-02-13
WO1994006766A1 (en) 1994-03-31
EP0659178A1 (en) 1995-06-28
EP0659178A4 (en) 1996-03-27
CA2135889A1 (en) 1994-03-31
US5252747A (en) 1993-10-12

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees