MX9202129A - Proteina compuesta de dos cadenas unidas de disulfuro, proceso para su preparacion y composicion farmaceutica que la contiene. - Google Patents

Proteina compuesta de dos cadenas unidas de disulfuro, proceso para su preparacion y composicion farmaceutica que la contiene.

Info

Publication number
MX9202129A
MX9202129A MX9202129A MX9202129A MX9202129A MX 9202129 A MX9202129 A MX 9202129A MX 9202129 A MX9202129 A MX 9202129A MX 9202129 A MX9202129 A MX 9202129A MX 9202129 A MX9202129 A MX 9202129A
Authority
MX
Mexico
Prior art keywords
chains
disulfide
united
preparation
pharmaceutical composition
Prior art date
Application number
MX9202129A
Other languages
English (en)
Inventor
Paolo Comoglio
Tiziana Crepaldi
Maria Prat
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919110202A external-priority patent/GB9110202D0/en
Priority claimed from GB919124896A external-priority patent/GB9124896D0/en
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of MX9202129A publication Critical patent/MX9202129A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
MX9202129A 1991-05-10 1992-05-07 Proteina compuesta de dos cadenas unidas de disulfuro, proceso para su preparacion y composicion farmaceutica que la contiene. MX9202129A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919110202A GB9110202D0 (en) 1991-05-10 1991-05-10 Truncated forms of the hepatocyte growth factor(hgf)receptor
GB919124896A GB9124896D0 (en) 1991-11-22 1991-11-22 Truncated forms of the hepatocyte growth factor(hgf)receptor

Publications (1)

Publication Number Publication Date
MX9202129A true MX9202129A (es) 1992-11-01

Family

ID=26298888

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9202129A MX9202129A (es) 1991-05-10 1992-05-07 Proteina compuesta de dos cadenas unidas de disulfuro, proceso para su preparacion y composicion farmaceutica que la contiene.

Country Status (18)

Country Link
US (1) US5571509A (es)
EP (2) EP0584125B1 (es)
JP (1) JP3293823B2 (es)
AT (1) ATE155525T1 (es)
AU (1) AU651452B2 (es)
CA (1) CA2102595C (es)
DE (1) DE69220940T2 (es)
DK (1) DK0584125T3 (es)
ES (1) ES2104914T3 (es)
FI (1) FI934934A (es)
GR (1) GR3024998T3 (es)
HU (1) HUT67009A (es)
IE (1) IE921485A1 (es)
IL (1) IL101809A0 (es)
MX (1) MX9202129A (es)
MY (1) MY108614A (es)
NZ (1) NZ242645A (es)
WO (1) WO1992020792A1 (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6344321B1 (en) * 1990-06-11 2002-02-05 Gilead Sciences, Inc. Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met
RU2146262C1 (ru) * 1993-06-30 2000-03-10 Фармация Энд Апджон С.П.А. Пептиды, способ их получения, фармацевтическая композиция и способ ее получения
US5464815A (en) * 1993-09-08 1995-11-07 Genentech, Inc. Inhibition of heparin-binding
US5646036A (en) * 1995-06-02 1997-07-08 Genentech, Inc. Nucleic acids encoding hepatocyte growth factor receptor antagonist antibodies
US5686292A (en) 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
US5855918A (en) * 1995-09-12 1999-01-05 Genentech, Inc. Cystic fibrosis therapy
AU7389496A (en) * 1995-10-05 1997-04-28 Genentech Inc. Methods and compositions for treating vascular stenosis
AU7254896A (en) * 1995-10-05 1997-04-28 Genentech Inc. Improved angiogenesis using hepatocyte growth factor
JP2000515735A (ja) * 1996-07-03 2000-11-28 ジェネンテック インコーポレーテッド 肝細胞成長因子レセプターアゴニスト
US5874306A (en) * 1996-12-12 1999-02-23 The Regents Of The University Of California Culturing human pancreatic endocrine cells in medium containing extracellular matrix from human bladder carcinoma cells
US6759206B1 (en) 1997-02-27 2004-07-06 Cellomics, Inc. System for cell-based screening
US6031155A (en) * 1997-06-05 2000-02-29 Cameron-Mills; Verena Arabinoxylan degradation
US20030118585A1 (en) 2001-10-17 2003-06-26 Agy Therapeutics Use of protein biomolecular targets in the treatment and visualization of brain tumors
AU2760602A (en) * 2001-03-23 2002-09-26 Agouron Pharmaceuticals, Inc. Catalytic domains of the human hepatocyte growth factor receptor tyrosine kinase, and materials and methods for identification of inhibitors thereof
US20100183573A1 (en) * 2001-09-14 2010-07-22 Compugen Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
US7678769B2 (en) * 2001-09-14 2010-03-16 Compugen, Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
US20070082337A1 (en) * 2004-01-27 2007-04-12 Compugen Ltd. Methods of identifying putative gene products by interspecies sequence comparison and biomolecular sequences uncovered thereby
US20040142325A1 (en) * 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
US20040248157A1 (en) * 2001-09-14 2004-12-09 Michal Ayalon-Soffer Novel polynucleotides encoding soluble polypeptides and methods using same
ITMI20031127A1 (it) 2003-06-05 2004-12-06 Uni Degli Studi Del Piemont E Orientale Am Anticorpi anti-hgf-r e loro uso
EP2367008A3 (en) * 2003-06-06 2014-12-24 Genentech, Inc. Modulating the interaction between HGF beta chain and C-Met
CA2548282A1 (en) * 2003-12-11 2005-06-30 Genentech, Inc. Methods and compositions for inhibiting c-met dimerization and activation
US20060147946A1 (en) * 2004-01-27 2006-07-06 Pinchas Akiva Novel calcium channel variants and methods of use thereof
SI1773885T1 (sl) 2004-08-05 2010-08-31 Genentech Inc Humanizirani anti-CMET antagonisti
MX2007012687A (es) 2005-04-15 2008-03-14 Genentech Inc Variantes de cadena beta de hgf.
EP1934256A2 (en) * 2005-09-30 2008-06-25 Compugen Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
CA2646048A1 (en) 2006-03-30 2007-11-08 Novartis Ag Compositions and methods of use for antibodies of c-met
EP2245055A2 (en) * 2008-01-31 2010-11-03 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
IL198545A0 (en) * 2008-05-14 2011-07-31 Metheresis Translational Res Sa High affinity binding site of hgfr and methods for identification of antagonists thereof
PA8849001A1 (es) 2008-11-21 2010-06-28 Lilly Co Eli Anticuerpos de c-met
KR101671378B1 (ko) * 2009-10-30 2016-11-01 삼성전자 주식회사 ｃ-Ｍｅｔ에 특이적으로 결합하는 항체 및 그의 용도
US20130315895A1 (en) 2010-07-01 2013-11-28 Takeda Pharmaceutical Company Limited COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET
WO2013003680A1 (en) 2011-06-30 2013-01-03 Genentech, Inc. Anti-c-met antibody formulations
WO2013043452A1 (en) 2011-09-20 2013-03-28 Eli Lilly And Company Anti-c-met antibodies
BR112016021383A2 (pt) 2014-03-24 2017-10-03 Genentech Inc Método para identificar um paciente com câncer que é susceptível ou menos susceptível a responder ao tratamento com um antagonista de cmet, método para identificar um paciente apresentando câncer previamente tratado, método para determinar a expressão do biomarcador hgf, antagonista anti-c-met e seu uso, kit de diagnóstico e seu método de preparo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2070995A1 (en) * 1989-12-27 1991-06-28 Thomas E. Kmiecik Diagnostic probe for detecting human stomach cancer
US5648273A (en) * 1989-12-27 1997-07-15 The United States Of America, As Represented By The Department Of Health And Human Services Hepatic growth factor receptor is the MET proto-oncogene

Also Published As

Publication number Publication date
IL101809A0 (en) 1992-12-30
IE921485A1 (en) 1992-11-18
GR3024998T3 (en) 1998-01-30
JP3293823B2 (ja) 2002-06-17
EP0520158A1 (en) 1992-12-30
HUT67009A (en) 1995-01-30
ATE155525T1 (de) 1997-08-15
HU9303182D0 (en) 1994-03-28
US5571509A (en) 1996-11-05
MY108614A (en) 1996-10-31
AU1672092A (en) 1992-12-30
JPH06508508A (ja) 1994-09-29
NZ242645A (en) 1994-11-25
DK0584125T3 (da) 1997-09-08
WO1992020792A1 (en) 1992-11-26
DE69220940T2 (de) 1998-01-15
CA2102595A1 (en) 1992-11-11
ES2104914T3 (es) 1997-10-16
FI934934A (fi) 1994-01-05
DE69220940D1 (de) 1997-08-21
EP0584125A1 (en) 1994-03-02
CA2102595C (en) 2003-01-14
EP0584125B1 (en) 1997-07-16
FI934934A0 (fi) 1993-11-08
AU651452B2 (en) 1994-07-21

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