FI934934A - Stympade former av hepatocytvaextfaktorreceptor - Google Patents

Stympade former av hepatocytvaextfaktorreceptor Download PDF

Info

Publication number
FI934934A
FI934934A FI934934A FI934934A FI934934A FI 934934 A FI934934 A FI 934934A FI 934934 A FI934934 A FI 934934A FI 934934 A FI934934 A FI 934934A FI 934934 A FI934934 A FI 934934A
Authority
FI
Finland
Prior art keywords
chain
kda
stympade
hepatocytvaextfaktorreceptor
former
Prior art date
Application number
FI934934A
Other languages
English (en)
Other versions
FI934934A0 (fi
Inventor
Paolo Comoglio
Tiziana Crepaldi
Maria Prat
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919110202A external-priority patent/GB9110202D0/en
Priority claimed from GB919124896A external-priority patent/GB9124896D0/en
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of FI934934A0 publication Critical patent/FI934934A0/fi
Publication of FI934934A publication Critical patent/FI934934A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82Translation products from oncogenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
FI934934A 1991-05-10 1993-11-08 Stympade former av hepatocytvaextfaktorreceptor FI934934A (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919110202A GB9110202D0 (en) 1991-05-10 1991-05-10 Truncated forms of the hepatocyte growth factor(hgf)receptor
GB919124896A GB9124896D0 (en) 1991-11-22 1991-11-22 Truncated forms of the hepatocyte growth factor(hgf)receptor
PCT/EP1992/000937 WO1992020792A1 (en) 1991-05-10 1992-04-30 Truncated forms of the hepatocyte growth factor (hgf) receptor

Publications (2)

Publication Number Publication Date
FI934934A0 FI934934A0 (fi) 1993-11-08
FI934934A true FI934934A (fi) 1994-01-05

Family

ID=26298888

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934934A FI934934A (fi) 1991-05-10 1993-11-08 Stympade former av hepatocytvaextfaktorreceptor

Country Status (18)

Country Link
US (1) US5571509A (fi)
EP (2) EP0584125B1 (fi)
JP (1) JP3293823B2 (fi)
AT (1) ATE155525T1 (fi)
AU (1) AU651452B2 (fi)
CA (1) CA2102595C (fi)
DE (1) DE69220940T2 (fi)
DK (1) DK0584125T3 (fi)
ES (1) ES2104914T3 (fi)
FI (1) FI934934A (fi)
GR (1) GR3024998T3 (fi)
HU (1) HUT67009A (fi)
IE (1) IE921485A1 (fi)
IL (1) IL101809A0 (fi)
MX (1) MX9202129A (fi)
MY (1) MY108614A (fi)
NZ (1) NZ242645A (fi)
WO (1) WO1992020792A1 (fi)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6344321B1 (en) * 1990-06-11 2002-02-05 Gilead Sciences, Inc. Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met
RU2146262C1 (ru) * 1993-06-30 2000-03-10 Фармация Энд Апджон С.П.А. Пептиды, способ их получения, фармацевтическая композиция и способ ее получения
US5464815A (en) * 1993-09-08 1995-11-07 Genentech, Inc. Inhibition of heparin-binding
US5686292A (en) 1995-06-02 1997-11-11 Genentech, Inc. Hepatocyte growth factor receptor antagonist antibodies and uses thereof
US5646036A (en) * 1995-06-02 1997-07-08 Genentech, Inc. Nucleic acids encoding hepatocyte growth factor receptor antagonist antibodies
JPH11512435A (ja) * 1995-09-12 1999-10-26 ジェネンテック インコーポレーテッド 嚢胞性繊維症の治療
WO1997012629A1 (en) * 1995-10-05 1997-04-10 Genentech, Inc. Improved angiogenesis using hepatocyte growth factor
WO1997012628A1 (en) * 1995-10-05 1997-04-10 Genentech, Inc. Methods and compositions for treating vascular stenosis
CA2258153C (en) * 1996-07-03 2004-08-17 Genentech, Inc. Hepatocyte growth factor receptor agonists and uses thereof
US5874306A (en) * 1996-12-12 1999-02-23 The Regents Of The University Of California Culturing human pancreatic endocrine cells in medium containing extracellular matrix from human bladder carcinoma cells
US6759206B1 (en) 1997-02-27 2004-07-06 Cellomics, Inc. System for cell-based screening
US6031155A (en) * 1997-06-05 2000-02-29 Cameron-Mills; Verena Arabinoxylan degradation
US20030118585A1 (en) 2001-10-17 2003-06-26 Agy Therapeutics Use of protein biomolecular targets in the treatment and visualization of brain tumors
AU2760602A (en) * 2001-03-23 2002-09-26 Agouron Pharmaceuticals, Inc. Catalytic domains of the human hepatocyte growth factor receptor tyrosine kinase, and materials and methods for identification of inhibitors thereof
US20060068405A1 (en) * 2004-01-27 2006-03-30 Alex Diber Methods and systems for annotating biomolecular sequences
US20040248157A1 (en) * 2001-09-14 2004-12-09 Michal Ayalon-Soffer Novel polynucleotides encoding soluble polypeptides and methods using same
US20100183573A1 (en) * 2001-09-14 2010-07-22 Compugen Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
US7678769B2 (en) * 2001-09-14 2010-03-16 Compugen, Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
WO2007036945A2 (en) * 2005-09-30 2007-04-05 Compugen Ltd. Hepatocyte growth factor receptor splice variants and methods of using same
US20040142325A1 (en) * 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
ITMI20031127A1 (it) * 2003-06-05 2004-12-06 Uni Degli Studi Del Piemont E Orientale Am Anticorpi anti-hgf-r e loro uso
PL1636593T3 (pl) * 2003-06-06 2009-08-31 Genentech Inc Modulowanie oddziaływania pomiędzy łańcuchem beta HGF i c-met.
JP2008507252A (ja) * 2003-12-11 2008-03-13 ジェネンテック・インコーポレーテッド C−met二量体化及び活性化を阻害するための方法と組成物
AU2005206389A1 (en) * 2004-01-27 2005-08-04 Compugen Ltd. Methods of identifying putative gene products by interspecies sequence comparison and biomolecular sequences uncovered thereby
AU2005267720B2 (en) 2004-08-05 2012-02-23 Genentech, Inc. Humanized anti-cmet antagonists
SG161281A1 (en) 2005-04-15 2010-05-27 Genentech Inc Hgf beta chain variants
EP2004693B1 (en) 2006-03-30 2012-06-06 Novartis AG Compositions and methods of use for antibodies of c-met
US20110052501A1 (en) * 2008-01-31 2011-03-03 Liat Dassa Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
IL198545A0 (en) 2008-05-14 2011-07-31 Metheresis Translational Res Sa High affinity binding site of hgfr and methods for identification of antagonists thereof
PA8849001A1 (es) * 2008-11-21 2010-06-28 Lilly Co Eli Anticuerpos de c-met
KR101671378B1 (ko) * 2009-10-30 2016-11-01 삼성전자 주식회사 c-Met에 특이적으로 결합하는 항체 및 그의 용도
WO2012003338A1 (en) 2010-07-01 2012-01-05 Takeda Pharmaceutical Company Limited COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET
US20130004484A1 (en) 2011-06-30 2013-01-03 Genentech, Inc. Anti-c-met antibody formulations
JP2014530201A (ja) 2011-09-20 2014-11-17 イーライ リリー アンド カンパニー 抗c−Met抗体
RU2016141385A (ru) 2014-03-24 2018-04-28 Дженентек, Инк. Лечение рака антагонистами с-мет и их корреляция с экспрессией hgf

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0507868A4 (en) * 1989-12-27 1992-11-04 Us Commerce Diagnostic probe for detecting human stomach cancer
US5648273A (en) * 1989-12-27 1997-07-15 The United States Of America, As Represented By The Department Of Health And Human Services Hepatic growth factor receptor is the MET proto-oncogene

Also Published As

Publication number Publication date
EP0584125B1 (en) 1997-07-16
WO1992020792A1 (en) 1992-11-26
MX9202129A (es) 1992-11-01
US5571509A (en) 1996-11-05
MY108614A (en) 1996-10-31
DE69220940D1 (de) 1997-08-21
ATE155525T1 (de) 1997-08-15
CA2102595C (en) 2003-01-14
IL101809A0 (en) 1992-12-30
NZ242645A (en) 1994-11-25
HUT67009A (en) 1995-01-30
FI934934A0 (fi) 1993-11-08
HU9303182D0 (en) 1994-03-28
DK0584125T3 (da) 1997-09-08
GR3024998T3 (en) 1998-01-30
ES2104914T3 (es) 1997-10-16
JP3293823B2 (ja) 2002-06-17
IE921485A1 (en) 1992-11-18
CA2102595A1 (en) 1992-11-11
EP0520158A1 (en) 1992-12-30
EP0584125A1 (en) 1994-03-02
DE69220940T2 (de) 1998-01-15
JPH06508508A (ja) 1994-09-29
AU1672092A (en) 1992-12-30
AU651452B2 (en) 1994-07-21

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Owner name: PHARMACIA & UPJOHN S.P.A.