MX358095B - Medios de cultivo celular. - Google Patents

Medios de cultivo celular.

Info

Publication number
MX358095B
MX358095B MX2015006099A MX2015006099A MX358095B MX 358095 B MX358095 B MX 358095B MX 2015006099 A MX2015006099 A MX 2015006099A MX 2015006099 A MX2015006099 A MX 2015006099A MX 358095 B MX358095 B MX 358095B
Authority
MX
Mexico
Prior art keywords
cell culture
cysteine
tyrosine
culture media
culture med
Prior art date
Application number
MX2015006099A
Other languages
English (en)
Other versions
MX2015006099A (es
Inventor
Von Hagen Joerg
André Breuning Marcel
Jasper Christian
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of MX2015006099A publication Critical patent/MX2015006099A/es
Publication of MX358095B publication Critical patent/MX358095B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0025—Culture media for plant cell or plant tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C12N2500/33—Amino acids other than alpha-amino carboxylic acids, e.g. beta-amino acids, taurine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La presente invención se refiere a medios de cultivo celular que comprenden derivados de éster inorgánico de tirosina y/o cisteína. La pobre solubilidad de la tirosina y la estabilidad con frecuencia no suficiente de la cisteína en medios de cultivo celular es superada sustituyéndola con un derivado de éster inorgánico, por ejemplo con un derivado fosforilado. Un proceso de alimentación por lotes caracterizado porque el medio de alimentación comprende al menos un derivado de éster inorgánico de tirosina en una concentración entre 10 y 30mmol/L.
MX2015006099A 2012-11-14 2013-11-14 Medios de cultivo celular. MX358095B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12007711 2012-11-14
PCT/EP2013/003441 WO2014075807A1 (en) 2012-11-14 2013-11-14 Cell culture med

Publications (2)

Publication Number Publication Date
MX2015006099A MX2015006099A (es) 2015-08-06
MX358095B true MX358095B (es) 2018-08-06

Family

ID=47189690

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015006099A MX358095B (es) 2012-11-14 2013-11-14 Medios de cultivo celular.

Country Status (13)

Country Link
US (2) US10030225B2 (es)
EP (2) EP3401319B1 (es)
JP (2) JP6433429B2 (es)
KR (1) KR102170858B1 (es)
CN (1) CN104812891B (es)
AR (2) AR093460A1 (es)
BR (2) BR122020000038B1 (es)
CA (2) CA2891279C (es)
DK (2) DK3401319T3 (es)
ES (1) ES2827701T3 (es)
MX (1) MX358095B (es)
SG (2) SG11201503579RA (es)
WO (1) WO2014075807A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR093460A1 (es) * 2012-11-14 2015-06-10 Merck Patent Ges Mit Beschränkter Haftung Medios de cultivo celular
CN106146360B (zh) * 2015-03-31 2020-05-15 深圳翰宇药业股份有限公司 一种制备酪氨酸-o-磺酸盐的方法
US10626364B2 (en) * 2015-07-30 2020-04-21 Merck Patent Gmbh Method for increasing the glutathione level in cells
EP3331986B1 (en) * 2015-08-05 2020-07-01 Merck Patent GmbH Process for producing cell culture media
DK3430072T3 (da) * 2016-03-17 2020-08-31 Merck Patent Gmbh Fremgangsmåde til oprensning af poloxamerer
SG11201809408SA (en) 2016-04-28 2018-11-29 Merck Patent Gmbh Method for reducing the trisulfide level in proteins
WO2018018613A1 (zh) 2016-07-29 2018-02-01 广东东阳光药业有限公司 一种提高抗体纯度的细胞培养基和培养方法
CN110799639A (zh) * 2017-06-27 2020-02-14 味之素株式会社 含有核黄素衍生物的培养基
CN110945118A (zh) * 2017-07-28 2020-03-31 日产化学株式会社 培养基添加用组合物及培养基添加用化合物以及使用了它们的细胞或组织的培养方法
US20210171901A1 (en) * 2017-11-16 2021-06-10 Life Technologies Corporation Streamlined methods for making liquid media
CN108823173A (zh) * 2018-07-24 2018-11-16 郑州伊美诺生物技术有限公司 用于杂交瘤细胞培养的补料培养基及其制备方法
CN109053797B (zh) * 2018-09-05 2021-06-29 成都百事兴科技实业有限公司 一种氧磷酸-l-酪氨酸的改进合成方法
JP2022506745A (ja) 2018-11-12 2022-01-17 エボニック オペレーションズ ゲーエムベーハー ケト酸を含む培地
CN111304144B (zh) * 2019-11-30 2023-04-07 河南普诺易生物制品研究院有限公司 一种昆虫细胞培养基及其制备方法
WO2023120637A1 (ja) * 2021-12-24 2023-06-29 味の素株式会社 動物細胞培養用の組成物
WO2023190692A1 (ja) * 2022-03-30 2023-10-05 富士フイルム株式会社 混合粉体の製造方法、混合粉体、粉体、及び、粉体培地
CN115305208A (zh) * 2022-09-16 2022-11-08 苏州星寰生物科技有限公司 一种米根霉固态发酵培养基及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55144896A (en) * 1979-04-24 1980-11-12 Takeda Chem Ind Ltd Preparation of cephalosporin antibiotic
EP0756003B1 (en) * 1994-02-18 1999-03-24 Teijin Limited Method of culturing animal cells
DE10117834B4 (de) * 2001-04-03 2005-10-27 Eberhard-Karls-Universität Tübingen Universitätsklinikum Verwendung von Phosphotyrosin zum Schutz von biologischem Material sowie kosmetische Zusammensetzung und Kultivierungsmedium
WO2003053932A1 (fr) * 2001-12-21 2003-07-03 Tohru Koike Complexes de zinc capables de pieger des substances portant des substituants anioniques
GB0208041D0 (en) * 2002-04-08 2002-05-22 Lonza Biologics Plc Method of culturing animal cells
WO2006062238A1 (ja) * 2004-12-07 2006-06-15 Ajinomoto Co., Inc. アミノ酸の微粉末及びその懸濁液
CN103397065A (zh) * 2006-09-13 2013-11-20 雅培制药有限公司 细胞培养改良
EP3960854B1 (en) * 2008-03-06 2024-07-17 Halozyme, Inc. Large-scale production of soluble hyaluronidase
JP5359409B2 (ja) * 2009-03-12 2013-12-04 味の素株式会社 Ｌ−システイン生産菌及びｌ−システインの製造法
CN102369290A (zh) * 2009-04-03 2012-03-07 帝斯曼知识产权资产管理有限公司 发酵工艺
AR093460A1 (es) * 2012-11-14 2015-06-10 Merck Patent Ges Mit Beschränkter Haftung Medios de cultivo celular

Also Published As

Publication number Publication date
JP6433429B2 (ja) 2018-12-05
US20150337258A1 (en) 2015-11-26
KR102170858B1 (ko) 2020-10-28
CA3112061A1 (en) 2014-05-22
SG11201503579RA (en) 2015-06-29
JP6650011B2 (ja) 2020-02-19
EP2920296A1 (en) 2015-09-23
CN104812891A (zh) 2015-07-29
ES2827701T3 (es) 2021-05-24
CN104812891B (zh) 2018-10-12
JP2015535423A (ja) 2015-12-14
AR117697A2 (es) 2021-08-25
WO2014075807A1 (en) 2014-05-22
US10030225B2 (en) 2018-07-24
CA2891279A1 (en) 2014-05-22
CA3112061C (en) 2022-08-09
SG10201811616SA (en) 2019-02-27
EP2920296B1 (en) 2018-07-18
CA2891279C (en) 2022-01-25
MX2015006099A (es) 2015-08-06
US20180230422A1 (en) 2018-08-16
EP3401319B1 (en) 2020-07-22
BR112015010948B1 (pt) 2021-10-26
DK2920296T3 (en) 2018-10-22
EP3401319A1 (en) 2018-11-14
KR20150085834A (ko) 2015-07-24
BR122020000038B1 (pt) 2021-11-03
US10619131B2 (en) 2020-04-14
AR093460A1 (es) 2015-06-10
JP2019030334A (ja) 2019-02-28
DK3401319T3 (da) 2020-09-07
BR112015010948A2 (pt) 2017-07-11

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